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M. thermoresistible (build 8) TH_0675 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1440989 - 1442722
length: 578

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0675-100% (578)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1098c-0.071.88% (569) hypothetical protein Mb1098c
M. gilvum PYR-GCKMflv_2035-0.074.29% (564) hypothetical protein Mflv_2035
M. tuberculosis H37RvRv1069c-0.071.88% (569) hypothetical protein Rv1069c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1509-0.069.45% (563) hypothetical protein MAB_1509
M. marinum MMMAR_4397-0.071.58% (556) hypothetical protein MMAR_4397
M. avium 104MAV_1193-0.069.61% (566) hypothetical protein MAV_1193
M. smegmatis MC2 155MSMEG_5278-0.079.06% (554) membrane-spanning protein
M. ulcerans Agy99MUL_0211-0.071.10% (519) hypothetical protein MUL_0211
M. vanbaalenii PYR-1Mvan_4682-0.074.43% (567) hypothetical protein Mvan_4682

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2035|M.gilvum_PYR-GCK          ----------------MTTGEAP--------------AEALEETPAPVPE
Mvan_4682|M.vanbaalenii_PYR-1       ---------------MTDTGEAP--------------AALIEQTPAGTKT
MSMEG_5278|M.smegmatis_MC2_155      ---------MTGTKTTEDVDRSG--------------GEPHAARAAGHHE
TH_0675|M.thermoresistible__bu      ---------------VTATPDKT--------------AEHASEEVAPQEH
MAB_1509|M.abscessus_ATCC_1997      MDTQAGGIKKGVAMAIDRDIDKD--------------QDEEQETAPAAAS
Mb1098c|M.bovis_AF2122/97           -------MTEPAAATTTNASDEP----------ATGAEQAVDTAATPQTP
Rv1069c|M.tuberculosis_H37Rv        -------MTEPAAATTTNASDEP----------ATGAEQAVDTAATPQTP
MMAR_4397|M.marinum_M               -------MSDMDSATSTDASDEA----------APAADESVETSGSGETA
MUL_0211|M.ulcerans_Agy99           -------MSDMDSATSTDASDEA----------APAADESVETSGSGETA
MAV_1193|M.avium_104                -------MSEPGSATDTDTGDEPSQQQTAPDGTRTGAQTAVAEHPAPKAP
                                                                                 .    

Mflv_2035|M.gilvum_PYR-GCK          APSRRG----WWIRRYTFTGTAVGLVFLFLSLTPSLLPRGPLFQGLVSGG
Mvan_4682|M.vanbaalenii_PYR-1       TAPRRA----WWVRHYTFTGTAVGFVFLWLSLTPSLLPRGPLFQGLVSGG
MSMEG_5278|M.smegmatis_MC2_155      APDKPA----WWVRHYTFFGTATGLVFIWLSLTPSLLPRGPLFQGLVSGG
TH_0675|M.thermoresistible__bu      KSEPGA----WWTRHYTFFGTAVGLVFLWFSLTPSLLPRGPLFQGIVSGA
MAB_1509|M.abscessus_ATCC_1997      KTTRPG----WWVRQYTFTGTAVGLVFLWLSMTPSLLPRGPLFQALVSGG
Mb1098c|M.bovis_AF2122/97           EPQPIR--STWWIRHYTFTGTAMGLVFVWFSMTPSLLPRGPLFQGLVSGI
Rv1069c|M.tuberculosis_H37Rv        EPQPIR--STWWIRHYTFTGTAMGLVFVWFSMTPSLLPRGPLFQGLVSGI
MMAR_4397|M.marinum_M               APKTTR--NAWWVRHYTFTGSAVGLIFLWFSMTPSLLPRGPLFQGLVSGI
MUL_0211|M.ulcerans_Agy99           APKTTR--NAWWVRHYTFTGSAVGLIFLWFSMTPSLLPRGPLFQGLVSGI
MAV_1193|M.avium_104                APGTPQPEKPWWVRHYTFTGTTVGLVFIWFSLTPSLLPRGAIFQGLVSGI
                                     .        ** *:*** *:: *::*:::*:********.:**.:*** 

Mflv_2035|M.gilvum_PYR-GCK          AGAIGYALGVFGVWLVRFMRSKDTSPPAPRWAWPTLVTVGLIGLIVMVFR
Mvan_4682|M.vanbaalenii_PYR-1       AGAIGYSLGVFAVWLVRFMRSKDTSPPAPRRAWPVLGVIGVIGMVIMVIQ
MSMEG_5278|M.smegmatis_MC2_155      AGAIGYGLGVFGVWLVRYMCSADSSPKAPRWAWVALVVVGIVGQILMIVY
TH_0675|M.thermoresistible__bu      AGAAGYGIGVFGVWLVRFMASRDSSPRAPRWAWIALIVVGTVVQLLMINY
MAB_1509|M.abscessus_ATCC_1997      SGAIGYALGVLVVWLVRYMRSQDSSPKAPPVAWRILVVLGLIGTVLMIVW
Mb1098c|M.bovis_AF2122/97           CGAFGYGLGVFAVWLVRYMRSHNSSPPPPRWAWPPLIAVGAVGMVGMAVQ
Rv1069c|M.tuberculosis_H37Rv        CGAFGYGLGVFAVWLVRYMRSHNSSPPPPRWAWPPLIAVGAVGMVGMAVQ
MMAR_4397|M.marinum_M               SGAIGYGLGVFAVWLVRYMRSQDDSPPPPRWVWPPLIAVGGVGIVLMAIW
MUL_0211|M.ulcerans_Agy99           SGAIGYGLGVFAVWLVRYMRSQDDSPPPPRWVWPPLIAVGGVGIVLMAIW
MAV_1193|M.avium_104                SGAIGYGLGVFAVWLYRYLWAKPSSPPPPRWAWKILIPVGAVGMVLMAIW
                                    .** **.:**: *** *:: :   ** .*  .*  *  :* :  : *   

Mflv_2035|M.gilvum_PYR-GCK          FHSWQDDVRDLMGVPRLTFWDYPLAAAISVVTLFLFVEIGQLVGRLVRFL
Mvan_4682|M.vanbaalenii_PYR-1       FHNWQDDVRDLMGVPRLTFWDYPLAAAISVVTLFVLVEIGQLVGRFVRFL
MSMEG_5278|M.smegmatis_MC2_155      FHVWQDEIRDFMGVPRLKFWDHPLTAVLSIVVLYVLVEIGQLIGKLVRFL
TH_0675|M.thermoresistible__bu      FRIWQDEVRDFMGVPRLTFWDHPLAGALSIAFLFTLVEIGKLIGRAVRFL
MAB_1509|M.abscessus_ATCC_1997      FHFWQDRVRDLMGVPRLSFWAHPQTAVMSIIVLFVLVEMGQQIRRLILFL
Mb1098c|M.bovis_AF2122/97           FHVWQDDVRDLMGVEHLRWYDYPLAAALSLVVLFTLVEIGQFIRWLFRFL
Rv1069c|M.tuberculosis_H37Rv        FHVWQDDVRDLMGVEHLRWYDYPLAAALSLVVLFTLVEIGQFIRWLFRFL
MMAR_4397|M.marinum_M               FHFWQDDVRDLMGVVHLKWYDYPLTAVVSLIVLFAFVEVGQFIRRLFSFL
MUL_0211|M.ulcerans_Agy99           FHFWQDDVRDLMGVVHLKWYDYPLTAVVSLIVLFAFVEVGQFIRRLFSFL
MAV_1193|M.avium_104                FHVWQDKVRDLMGVAHLKWYDYPVAGVLSLVVLFTCVEIGQFTRWLVSFL
                                    *: *** :**:*** :* :: :* :..:*:  *:  **:*:     . **

Mflv_2035|M.gilvum_PYR-GCK          VRQVDRVAPPRIAAVVVVALLLALTIALLNGVVVRFAMSTINSTFASVND
Mvan_4682|M.vanbaalenii_PYR-1       DRQVKRVAPPRVSAVVVVTLLLALTIALLNGVVVRFAMSTINKTFAAVND
MSMEG_5278|M.smegmatis_MC2_155      VRQLDRVAPPRVSAVVVVALLLALSIALLNGVVARFAMSTINKTFAAVND
TH_0675|M.thermoresistible__bu      NGQLRRFAPPRVSAVVSVLLVVALIIAILNGIVVRWAMSTINSTFAAVNE
MAB_1509|M.abscessus_ATCC_1997      IERLNRVAPKRVSAVVAVTLVVVLAMALINGVVVRVAMDFLNNTFSAVNN
Mb1098c|M.bovis_AF2122/97           VGQVDRIAPFRVSAAIVVVLLVVLTITLLNGVVLKFAMNSMNSTFAAVNN
Rv1069c|M.tuberculosis_H37Rv        VGQVDRIAPFRVSAAIVVVLLVVLTITLLNGVVLKFAMNSMNSTFAAVNN
MMAR_4397|M.marinum_M               VRQLDRIAPFRLSATIVVVLLVTLTITVLNGVVLKFAMHSMNSTFASVND
MUL_0211|M.ulcerans_Agy99           VRQLDRIAPFRLSATIVVVLLVTLTITVLNGVVLKFAMHSMNSTFASVND
MAV_1193|M.avium_104                VGRLDRIAPFRLSATIVVALLVVLTITLLNGVVLKFAMRTMNNTFASANN
                                      :: *.** *::*.: * *::.* ::::**:* : **  :*.**::.*:

Mflv_2035|M.gilvum_PYR-GCK          ETDPDNPAPQSVLRSGGPESLVSWESLGHQGRVFVANGPTVDELTSFNGS
Mvan_4682|M.vanbaalenii_PYR-1       ETDPDFAAPDSDLRSGGPQSLVSWESLGHQGRVFISGGPSVEDLTEFNGD
MSMEG_5278|M.smegmatis_MC2_155      EDSPDFSAPTSPLRSGGPGSLASWESLGHQGRVFVASAPTVQQLSEFNGA
TH_0675|M.thermoresistible__bu      EDDPAFPAPTTPLRSGGPGSLVSWESLGHQGRIFVAAGPTVEQLSEFNGA
MAB_1509|M.abscessus_ATCC_1997      EENPDNPAPTTSLRSGGPGSLVSWASLGNQGRAFVGGGATAQELSAFNKT
Mb1098c|M.bovis_AF2122/97           EMNPDSAPPKTPLRSGGPGSLVSWESLGHQGRIFVHSGPTIADLTAFNGT
Rv1069c|M.tuberculosis_H37Rv        EMNPDSAPPKTPLRSGGPGSLVSWESLGHQGRIFVHSGPTIADLTAFNGT
MMAR_4397|M.marinum_M               ELDPNSAPPNTALRSGGPQSLVSWESLGHQGRVFVEGGPSRADLTAFNGS
MUL_0211|M.ulcerans_Agy99           ELDPNSAPPNTALRSGGPQSLVSWESLGHQGRVFVEGGPSRADLTAFNGS
MAV_1193|M.avium_104                EMSPDTAPPKTPLRSGGPESLVSWESLGHQGRVFIEGGPRVEQLTAFNGA
                                    * .*  ..* : ****** **.** ***:*** *:  ..   :*: **  

Mflv_2035|M.gilvum_PYR-GCK          PATEPIRAYAGLNSADGIKETAALAAQELQRTGGLQRAVVAVATTTGTGW
Mvan_4682|M.vanbaalenii_PYR-1       PATEPIRAYAGLNSADGIKETAALAAQELQRTGGLERAVVAVATTTGTGW
MSMEG_5278|M.smegmatis_MC2_155      PAVEPIRAYAGLHSADGIKATAALAARELERTGGLDRAVVAVATTTGTGW
TH_0675|M.thermoresistible__bu      PAVEPIRAYAGLNSANGIRETAALAARELQRTGGLNRQVVAVATTTGTGW
MAB_1509|M.abscessus_ATCC_1997      PATEPIRAYAGLESADGIKATAELAARELEREGGLHRKVVAVATTTGTGW
Mb1098c|M.bovis_AF2122/97           PAVEPIRTYAGLNSADGIMATAELAARELARTGGLRRAVVAVATSTGTGW
Rv1069c|M.tuberculosis_H37Rv        PAVEPIRTYAGLNSADGIMATAELAARELARTGGLRRAVVAVATSTGTGW
MMAR_4397|M.marinum_M               PATEPIRAYAGLNSANGIIATAELAARELQRTGGLQRAVVAVATTTGTGW
MUL_0211|M.ulcerans_Agy99           PATEPIRAYAGLNSANGIIATAELAARELQRTGGLQRAVVAVATTTGTGW
MAV_1193|M.avium_104                PATEPIRAYAGLNSADGITATAELAARELQRTGGLRRAVVAVATTTGTGW
                                    **.****:****.**:**  ** ***:** * *** * ******:*****

Mflv_2035|M.gilvum_PYR-GCK          INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
Mvan_4682|M.vanbaalenii_PYR-1       INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
MSMEG_5278|M.smegmatis_MC2_155      INNAEATALEYMYNGDTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
TH_0675|M.thermoresistible__bu      INEAEASALEYMFNGDTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MAB_1509|M.abscessus_ATCC_1997      INQAEADALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
Mb1098c|M.bovis_AF2122/97           INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARHAGEALFEA
Rv1069c|M.tuberculosis_H37Rv        INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARHAGEALFEA
MMAR_4397|M.marinum_M               INEAEASALEYMYNGNTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MUL_0211|M.ulcerans_Agy99           INEAEASALEYMYNGNTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MAV_1193|M.avium_104                INEAEATALEYMYNGNTAIVSMQYSFLPSWLSFLVDKENARHAGQALFEA
                                    **:*** *****:**:*********:***************:**:*****

Mflv_2035|M.gilvum_PYR-GCK          IDALVREMPEAQRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
Mvan_4682|M.vanbaalenii_PYR-1       VDALIREMPEAQRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
MSMEG_5278|M.smegmatis_MC2_155      VDELIRERPEADRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
TH_0675|M.thermoresistible__bu      VDALIREMPEAERPRLVVFGESLGSFGGEAPFLALNNLVARTDGALFSGP
MAB_1509|M.abscessus_ATCC_1997      VSARVRAMPEAVRPKLVVFGESLGSFGGEAPFLSVNNIVARTDGALFSGP
Mb1098c|M.bovis_AF2122/97           VDKLIRQLPESQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
Rv1069c|M.tuberculosis_H37Rv        VDKLIRQLPESQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MMAR_4397|M.marinum_M               VDKLIRQMPEFQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MUL_0211|M.ulcerans_Agy99           VDKLIRQMPEFQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MAV_1193|M.avium_104                VDRLVRQLPEAQRPKLVVFGESLGSFGGEAPFMSLNNVLARTDGALFSGP
                                    :.  :*  **  **:*****************: :**::***********

Mflv_2035|M.gilvum_PYR-GCK          TFNNTIWEDLTRNRDPGSPEWLPIYDRGENVRFVADPADFARPQDPWEQP
Mvan_4682|M.vanbaalenii_PYR-1       TFNNTIWTDLTRNRDAGSPEWLPVFDKGENVRFVAEPRDLQRPHDPWEQP
MSMEG_5278|M.smegmatis_MC2_155      TFNNTIWADLTRNRDPGSPEWLPIYDKGENVRFVAEAGDLGRPEDPWSTP
TH_0675|M.thermoresistible__bu      TFNNEIWAELTRTRDPGSPMWLPIYDRGANVRFVSRPDDLNRPDAPWGEP
MAB_1509|M.abscessus_ATCC_1997      TFNNSMWLEATHNRDDGSPEVLPIYDQGRNVRFVSRPEDLKRPADPWARP
Mb1098c|M.bovis_AF2122/97           TFNNTVWNSLTANRDAGSPQWLPIYDDGRNVRFVARARDLQRPDAPWGRP
Rv1069c|M.tuberculosis_H37Rv        TFNNTVWNSLTANRDAGSPQWLPIYDDGRNVRFVARARDLQRPDAPWGRP
MMAR_4397|M.marinum_M               TFNNTVWTELTANRDPGSPEWLPIYDDGYNVRFIARASDLQRPDAPWGKP
MUL_0211|M.ulcerans_Agy99           TFNNTVWTELTANRDPGSPEWLPIYDDGYNVRFIARASDLQRPDAPWGKP
MAV_1193|M.avium_104                TFNNTIWTDLTSTRDAGSPEWLPIYNDGRNVRFVARAANLARPKDPWDHP
                                    **** :* . * .** ***  **::: * ****:: . :: **  **  *

Mflv_2035|M.gilvum_PYR-GCK          RVVYLQHASDPIAWWNTDLLFTKPDWLREARGSDVSPNMEWIPVVTFLQV
Mvan_4682|M.vanbaalenii_PYR-1       RVVYLQHASDPIAWWNPDLLFARPDWLHEPRGYDVSPGMEWIPVVTFLQV
MSMEG_5278|M.smegmatis_MC2_155      RVVYLQHASDPIAWWNTDLLFSKPDWLREPRGYDVSPHTEWIPVVTFLQV
TH_0675|M.thermoresistible__bu      RVVYLQHASDPIAWWSPDLLFAEPDWLKEPRGYDVSGRTQWIPVVTFLQV
MAB_1509|M.abscessus_ATCC_1997      RIVYLQHASDPIAWFNPDLILSKPDWLREPRGYDVLPSMEWIPFVTFLQV
Mb1098c|M.bovis_AF2122/97           RVVYLQHASDPIAWWTPRLLFREPDWLREQRGYDVLPQTRWIPVVTFVQV
Rv1069c|M.tuberculosis_H37Rv        RVVYLQHASDPIAWWTPRLLFREPDWLREQRGYDVLPQTRWIPVVTFVQV
MMAR_4397|M.marinum_M               RVVYLQHASDPIAWWTPDLLFSEPDWLREKRGYDVLPQTRWIPLVTFLQV
MUL_0211|M.ulcerans_Agy99           RVVYLQHASDPIAWWTPDLLFSEPDWLREKRGYDVLPQTRWIPLVTFLQV
MAV_1193|M.avium_104                RVVYLQHASDPIAWWTTDLLFARPDWLKERRGYDVLPETTWIPVVTFLQV
                                    *:************:.. *:: .****:* ** **     ***.***:**

Mflv_2035|M.gilvum_PYR-GCK          SADMAVAVDVPDG-----------HGHVYVRNVAN------AWAAILEPP
Mvan_4682|M.vanbaalenii_PYR-1       SADMAVAVNVPDG-----------HGHVYVRNVAD------AWASIMLPP
MSMEG_5278|M.smegmatis_MC2_155      SADMAVAVDVPDG-----------HGHVYVKNVAD------AWAAIMRPP
TH_0675|M.thermoresistible__bu      AADMAVATQVPDG-----------HGHRYVHTVAD------AWAAVLQPP
MAB_1509|M.abscessus_ATCC_1997      SADMAVAVDVPDG-----------HGHVYVKAVAD------AWAAVLQPP
Mb1098c|M.bovis_AF2122/97           SADMAVATHVPDG-----------HGHRYVATVAD------GWAAVLSPP
Rv1069c|M.tuberculosis_H37Rv        SADMAVATHVPDG-----------HGHRYVATVAD------GWAAVLSPP
MMAR_4397|M.marinum_M               SADMAVAVDVPDG-----------HGHRYVSNVAN------GWAAVLSPP
MUL_0211|M.ulcerans_Agy99           SADMAVAVDVPDGMDTATSATSPTAGPRSCRRRAGPPRKPSGYDRCCAPT
MAV_1193|M.avium_104                SADMAVAQNVPDG-----------HGHHYVADVAD------AWAAVLSPP
                                    :****** .****            *       *.      .:     *.

Mflv_2035|M.gilvum_PYR-GCK          GWTPEKTEKLRTMLRSDENS-------
Mvan_4682|M.vanbaalenii_PYR-1       GWTQDKTEKLRGLLRSDENS-------
MSMEG_5278|M.smegmatis_MC2_155      GWTPEKTERLRPLLTNNESA-------
TH_0675|M.thermoresistible__bu      GWTHEKTERLRPLLHADAKPNEVSPTK
MAB_1509|M.abscessus_ATCC_1997      GWTPEKTQRLRPLLHSGA---------
Mb1098c|M.bovis_AF2122/97           GWTQQKTERLQPLLHANAKPFGS----
Rv1069c|M.tuberculosis_H37Rv        GWTQQKTERLQPLLHANAKPFGS----
MMAR_4397|M.marinum_M               GWTPEKTERLRPLLRAN----------
MUL_0211|M.ulcerans_Agy99           SGCGVGRRSGRPSIVSR----------
MAV_1193|M.avium_104                GWTPDKTDRLRPLLHANG---------
                                    .         :  :