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VTGTKTTEDVDRSGGEPHAARAAGHHEAPDKPAWWVRHYTFFGTATGLVFIWLSLTPSLLPRGPLFQGLV SGGAGAIGYGLGVFGVWLVRYMCSADSSPKAPRWAWVALVVVGIVGQILMIVYFHVWQDEIRDFMGVPRL KFWDHPLTAVLSIVVLYVLVEIGQLIGKLVRFLVRQLDRVAPPRVSAVVVVALLLALSIALLNGVVARFA MSTINKTFAAVNDEDSPDFSAPTSPLRSGGPGSLASWESLGHQGRVFVASAPTVQQLSEFNGAPAVEPIR AYAGLHSADGIKATAALAARELERTGGLDRAVVAVATTTGTGWINNAEATALEYMYNGDTAIVSMQYSYL PSWLSFLVDKENARQAGQALFEAVDELIRERPEADRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALF SGPTFNNTIWADLTRNRDPGSPEWLPIYDKGENVRFVAEAGDLGRPEDPWSTPRVVYLQHASDPIAWWNT DLLFSKPDWLREPRGYDVSPHTEWIPVVTFLQVSADMAVAVDVPDGHGHVYVKNVADAWAAIMRPPGWTP EKTERLRPLLTNNESA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5278 | - | - | 100% (576) | membrane-spanning protein |
| M. smegmatis MC2 155 | MSMEG_5823 | - | e-121 | 44.40% (554) | membrane-spanning protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1098c | - | 0.0 | 71.08% (574) | hypothetical protein Mb1098c |
| M. gilvum PYR-GCK | Mflv_2035 | - | 0.0 | 80.91% (550) | hypothetical protein Mflv_2035 |
| M. tuberculosis H37Rv | Rv1069c | - | 0.0 | 71.08% (574) | hypothetical protein Rv1069c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1509 | - | 0.0 | 73.31% (562) | hypothetical protein MAB_1509 |
| M. marinum M | MMAR_4397 | - | 0.0 | 71.60% (574) | hypothetical protein MMAR_4397 |
| M. avium 104 | MAV_1193 | - | 0.0 | 71.97% (578) | hypothetical protein MAV_1193 |
| M. thermoresistible (build 8) | TH_0675 | - | 0.0 | 79.06% (554) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0211 | - | 0.0 | 71.32% (537) | hypothetical protein MUL_0211 |
| M. vanbaalenii PYR-1 | Mvan_4682 | - | 0.0 | 80.14% (554) | hypothetical protein Mvan_4682 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2035|M.gilvum_PYR-GCK ----------------MTTGEAP--------------AEALEETPAPVPE
Mvan_4682|M.vanbaalenii_PYR-1 ---------------MTDTGEAP--------------AALIEQTPAGTKT
MSMEG_5278|M.smegmatis_MC2_155 ---------MTGTKTTEDVDRSG--------------GEPHAARAAGHHE
TH_0675|M.thermoresistible__bu ---------------VTATPDKT--------------AEHASEEVAPQEH
MAB_1509|M.abscessus_ATCC_1997 MDTQAGGIKKGVAMAIDRDIDKD--------------QDEEQETAPAAAS
Mb1098c|M.bovis_AF2122/97 -------MTEPAAATTTNASDEP----------ATGAEQAVDTAATPQTP
Rv1069c|M.tuberculosis_H37Rv -------MTEPAAATTTNASDEP----------ATGAEQAVDTAATPQTP
MMAR_4397|M.marinum_M -------MSDMDSATSTDASDEA----------APAADESVETSGSGETA
MUL_0211|M.ulcerans_Agy99 -------MSDMDSATSTDASDEA----------APAADESVETSGSGETA
MAV_1193|M.avium_104 -------MSEPGSATDTDTGDEPSQQQTAPDGTRTGAQTAVAEHPAPKAP
.
Mflv_2035|M.gilvum_PYR-GCK APSRRG----WWIRRYTFTGTAVGLVFLFLSLTPSLLPRGPLFQGLVSGG
Mvan_4682|M.vanbaalenii_PYR-1 TAPRRA----WWVRHYTFTGTAVGFVFLWLSLTPSLLPRGPLFQGLVSGG
MSMEG_5278|M.smegmatis_MC2_155 APDKPA----WWVRHYTFFGTATGLVFIWLSLTPSLLPRGPLFQGLVSGG
TH_0675|M.thermoresistible__bu KSEPGA----WWTRHYTFFGTAVGLVFLWFSLTPSLLPRGPLFQGIVSGA
MAB_1509|M.abscessus_ATCC_1997 KTTRPG----WWVRQYTFTGTAVGLVFLWLSMTPSLLPRGPLFQALVSGG
Mb1098c|M.bovis_AF2122/97 EPQPIR--STWWIRHYTFTGTAMGLVFVWFSMTPSLLPRGPLFQGLVSGI
Rv1069c|M.tuberculosis_H37Rv EPQPIR--STWWIRHYTFTGTAMGLVFVWFSMTPSLLPRGPLFQGLVSGI
MMAR_4397|M.marinum_M APKTTR--NAWWVRHYTFTGSAVGLIFLWFSMTPSLLPRGPLFQGLVSGI
MUL_0211|M.ulcerans_Agy99 APKTTR--NAWWVRHYTFTGSAVGLIFLWFSMTPSLLPRGPLFQGLVSGI
MAV_1193|M.avium_104 APGTPQPEKPWWVRHYTFTGTTVGLVFIWFSLTPSLLPRGAIFQGLVSGI
. ** *:*** *:: *::*:::*:********.:**.:***
Mflv_2035|M.gilvum_PYR-GCK AGAIGYALGVFGVWLVRFMRSKDTSPPAPRWAWPTLVTVGLIGLIVMVFR
Mvan_4682|M.vanbaalenii_PYR-1 AGAIGYSLGVFAVWLVRFMRSKDTSPPAPRRAWPVLGVIGVIGMVIMVIQ
MSMEG_5278|M.smegmatis_MC2_155 AGAIGYGLGVFGVWLVRYMCSADSSPKAPRWAWVALVVVGIVGQILMIVY
TH_0675|M.thermoresistible__bu AGAAGYGIGVFGVWLVRFMASRDSSPRAPRWAWIALIVVGTVVQLLMINY
MAB_1509|M.abscessus_ATCC_1997 SGAIGYALGVLVVWLVRYMRSQDSSPKAPPVAWRILVVLGLIGTVLMIVW
Mb1098c|M.bovis_AF2122/97 CGAFGYGLGVFAVWLVRYMRSHNSSPPPPRWAWPPLIAVGAVGMVGMAVQ
Rv1069c|M.tuberculosis_H37Rv CGAFGYGLGVFAVWLVRYMRSHNSSPPPPRWAWPPLIAVGAVGMVGMAVQ
MMAR_4397|M.marinum_M SGAIGYGLGVFAVWLVRYMRSQDDSPPPPRWVWPPLIAVGGVGIVLMAIW
MUL_0211|M.ulcerans_Agy99 SGAIGYGLGVFAVWLVRYMRSQDDSPPPPRWVWPPLIAVGGVGIVLMAIW
MAV_1193|M.avium_104 SGAIGYGLGVFAVWLYRYLWAKPSSPPPPRWAWKILIPVGAVGMVLMAIW
.** **.:**: *** *:: : ** .* .* * :* : : *
Mflv_2035|M.gilvum_PYR-GCK FHSWQDDVRDLMGVPRLTFWDYPLAAAISVVTLFLFVEIGQLVGRLVRFL
Mvan_4682|M.vanbaalenii_PYR-1 FHNWQDDVRDLMGVPRLTFWDYPLAAAISVVTLFVLVEIGQLVGRFVRFL
MSMEG_5278|M.smegmatis_MC2_155 FHVWQDEIRDFMGVPRLKFWDHPLTAVLSIVVLYVLVEIGQLIGKLVRFL
TH_0675|M.thermoresistible__bu FRIWQDEVRDFMGVPRLTFWDHPLAGALSIAFLFTLVEIGKLIGRAVRFL
MAB_1509|M.abscessus_ATCC_1997 FHFWQDRVRDLMGVPRLSFWAHPQTAVMSIIVLFVLVEMGQQIRRLILFL
Mb1098c|M.bovis_AF2122/97 FHVWQDDVRDLMGVEHLRWYDYPLAAALSLVVLFTLVEIGQFIRWLFRFL
Rv1069c|M.tuberculosis_H37Rv FHVWQDDVRDLMGVEHLRWYDYPLAAALSLVVLFTLVEIGQFIRWLFRFL
MMAR_4397|M.marinum_M FHFWQDDVRDLMGVVHLKWYDYPLTAVVSLIVLFAFVEVGQFIRRLFSFL
MUL_0211|M.ulcerans_Agy99 FHFWQDDVRDLMGVVHLKWYDYPLTAVVSLIVLFAFVEVGQFIRRLFSFL
MAV_1193|M.avium_104 FHVWQDKVRDLMGVAHLKWYDYPVAGVLSLVVLFTCVEIGQFTRWLVSFL
*: *** :**:*** :* :: :* :..:*: *: **:*: . **
Mflv_2035|M.gilvum_PYR-GCK VRQVDRVAPPRIAAVVVVALLLALTIALLNGVVVRFAMSTINSTFASVND
Mvan_4682|M.vanbaalenii_PYR-1 DRQVKRVAPPRVSAVVVVTLLLALTIALLNGVVVRFAMSTINKTFAAVND
MSMEG_5278|M.smegmatis_MC2_155 VRQLDRVAPPRVSAVVVVALLLALSIALLNGVVARFAMSTINKTFAAVND
TH_0675|M.thermoresistible__bu NGQLRRFAPPRVSAVVSVLLVVALIIAILNGIVVRWAMSTINSTFAAVNE
MAB_1509|M.abscessus_ATCC_1997 IERLNRVAPKRVSAVVAVTLVVVLAMALINGVVVRVAMDFLNNTFSAVNN
Mb1098c|M.bovis_AF2122/97 VGQVDRIAPFRVSAAIVVVLLVVLTITLLNGVVLKFAMNSMNSTFAAVNN
Rv1069c|M.tuberculosis_H37Rv VGQVDRIAPFRVSAAIVVVLLVVLTITLLNGVVLKFAMNSMNSTFAAVNN
MMAR_4397|M.marinum_M VRQLDRIAPFRLSATIVVVLLVTLTITVLNGVVLKFAMHSMNSTFASVND
MUL_0211|M.ulcerans_Agy99 VRQLDRIAPFRLSATIVVVLLVTLTITVLNGVVLKFAMHSMNSTFASVND
MAV_1193|M.avium_104 VGRLDRIAPFRLSATIVVALLVVLTITLLNGVVLKFAMRTMNNTFASANN
:: *.** *::*.: * *::.* ::::**:* : ** :*.**::.*:
Mflv_2035|M.gilvum_PYR-GCK ETDPDNPAPQSVLRSGGPESLVSWESLGHQGRVFVANGPTVDELTSFNGS
Mvan_4682|M.vanbaalenii_PYR-1 ETDPDFAAPDSDLRSGGPQSLVSWESLGHQGRVFISGGPSVEDLTEFNGD
MSMEG_5278|M.smegmatis_MC2_155 EDSPDFSAPTSPLRSGGPGSLASWESLGHQGRVFVASAPTVQQLSEFNGA
TH_0675|M.thermoresistible__bu EDDPAFPAPTTPLRSGGPGSLVSWESLGHQGRIFVAAGPTVEQLSEFNGA
MAB_1509|M.abscessus_ATCC_1997 EENPDNPAPTTSLRSGGPGSLVSWASLGNQGRAFVGGGATAQELSAFNKT
Mb1098c|M.bovis_AF2122/97 EMNPDSAPPKTPLRSGGPGSLVSWESLGHQGRIFVHSGPTIADLTAFNGT
Rv1069c|M.tuberculosis_H37Rv EMNPDSAPPKTPLRSGGPGSLVSWESLGHQGRIFVHSGPTIADLTAFNGT
MMAR_4397|M.marinum_M ELDPNSAPPNTALRSGGPQSLVSWESLGHQGRVFVEGGPSRADLTAFNGS
MUL_0211|M.ulcerans_Agy99 ELDPNSAPPNTALRSGGPQSLVSWESLGHQGRVFVEGGPSRADLTAFNGS
MAV_1193|M.avium_104 EMSPDTAPPKTPLRSGGPESLVSWESLGHQGRVFIEGGPRVEQLTAFNGA
* .* ..* : ****** **.** ***:*** *: .. :*: **
Mflv_2035|M.gilvum_PYR-GCK PATEPIRAYAGLNSADGIKETAALAAQELQRTGGLQRAVVAVATTTGTGW
Mvan_4682|M.vanbaalenii_PYR-1 PATEPIRAYAGLNSADGIKETAALAAQELQRTGGLERAVVAVATTTGTGW
MSMEG_5278|M.smegmatis_MC2_155 PAVEPIRAYAGLHSADGIKATAALAARELERTGGLDRAVVAVATTTGTGW
TH_0675|M.thermoresistible__bu PAVEPIRAYAGLNSANGIRETAALAARELQRTGGLNRQVVAVATTTGTGW
MAB_1509|M.abscessus_ATCC_1997 PATEPIRAYAGLESADGIKATAELAARELEREGGLHRKVVAVATTTGTGW
Mb1098c|M.bovis_AF2122/97 PAVEPIRTYAGLNSADGIMATAELAARELARTGGLRRAVVAVATSTGTGW
Rv1069c|M.tuberculosis_H37Rv PAVEPIRTYAGLNSADGIMATAELAARELARTGGLRRAVVAVATSTGTGW
MMAR_4397|M.marinum_M PATEPIRAYAGLNSANGIIATAELAARELQRTGGLQRAVVAVATTTGTGW
MUL_0211|M.ulcerans_Agy99 PATEPIRAYAGLNSANGIIATAELAARELQRTGGLQRAVVAVATTTGTGW
MAV_1193|M.avium_104 PATEPIRAYAGLNSADGITATAELAARELQRTGGLRRAVVAVATTTGTGW
**.****:****.**:** ** ***:** * *** * ******:*****
Mflv_2035|M.gilvum_PYR-GCK INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
Mvan_4682|M.vanbaalenii_PYR-1 INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
MSMEG_5278|M.smegmatis_MC2_155 INNAEATALEYMYNGDTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
TH_0675|M.thermoresistible__bu INEAEASALEYMFNGDTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MAB_1509|M.abscessus_ATCC_1997 INQAEADALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARQAGQALFEA
Mb1098c|M.bovis_AF2122/97 INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARHAGEALFEA
Rv1069c|M.tuberculosis_H37Rv INEAEASALEYMYNGDTAIVSMQYSFLPSWLSFLVDKENARHAGEALFEA
MMAR_4397|M.marinum_M INEAEASALEYMYNGNTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MUL_0211|M.ulcerans_Agy99 INEAEASALEYMYNGNTAIVSMQYSYLPSWLSFLVDKENARQAGQALFEA
MAV_1193|M.avium_104 INEAEATALEYMYNGNTAIVSMQYSFLPSWLSFLVDKENARHAGQALFEA
**:*** *****:**:*********:***************:**:*****
Mflv_2035|M.gilvum_PYR-GCK IDALVREMPEAQRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
Mvan_4682|M.vanbaalenii_PYR-1 VDALIREMPEAQRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
MSMEG_5278|M.smegmatis_MC2_155 VDELIRERPEADRPKLVVFGESLGSFGGEAPFLALNNLIARTDGALFSGP
TH_0675|M.thermoresistible__bu VDALIREMPEAERPRLVVFGESLGSFGGEAPFLALNNLVARTDGALFSGP
MAB_1509|M.abscessus_ATCC_1997 VSARVRAMPEAVRPKLVVFGESLGSFGGEAPFLSVNNIVARTDGALFSGP
Mb1098c|M.bovis_AF2122/97 VDKLIRQLPESQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
Rv1069c|M.tuberculosis_H37Rv VDKLIRQLPESQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MMAR_4397|M.marinum_M VDKLIRQMPEFQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MUL_0211|M.ulcerans_Agy99 VDKLIRQMPEFQRPKLVVFGESLGSFGGEAPFMNLNNILARTDGALFSGP
MAV_1193|M.avium_104 VDRLVRQLPEAQRPKLVVFGESLGSFGGEAPFMSLNNVLARTDGALFSGP
:. :* ** **:*****************: :**::***********
Mflv_2035|M.gilvum_PYR-GCK TFNNTIWEDLTRNRDPGSPEWLPIYDRGENVRFVADPADFARPQDPWEQP
Mvan_4682|M.vanbaalenii_PYR-1 TFNNTIWTDLTRNRDAGSPEWLPVFDKGENVRFVAEPRDLQRPHDPWEQP
MSMEG_5278|M.smegmatis_MC2_155 TFNNTIWADLTRNRDPGSPEWLPIYDKGENVRFVAEAGDLGRPEDPWSTP
TH_0675|M.thermoresistible__bu TFNNEIWAELTRTRDPGSPMWLPIYDRGANVRFVSRPDDLNRPDAPWGEP
MAB_1509|M.abscessus_ATCC_1997 TFNNSMWLEATHNRDDGSPEVLPIYDQGRNVRFVSRPEDLKRPADPWARP
Mb1098c|M.bovis_AF2122/97 TFNNTVWNSLTANRDAGSPQWLPIYDDGRNVRFVARARDLQRPDAPWGRP
Rv1069c|M.tuberculosis_H37Rv TFNNTVWNSLTANRDAGSPQWLPIYDDGRNVRFVARARDLQRPDAPWGRP
MMAR_4397|M.marinum_M TFNNTVWTELTANRDPGSPEWLPIYDDGYNVRFIARASDLQRPDAPWGKP
MUL_0211|M.ulcerans_Agy99 TFNNTVWTELTANRDPGSPEWLPIYDDGYNVRFIARASDLQRPDAPWGKP
MAV_1193|M.avium_104 TFNNTIWTDLTSTRDAGSPEWLPIYNDGRNVRFVARAANLARPKDPWDHP
**** :* . * .** *** **::: * ****:: . :: ** ** *
Mflv_2035|M.gilvum_PYR-GCK RVVYLQHASDPIAWWNTDLLFTKPDWLREARGSDVSPNMEWIPVVTFLQV
Mvan_4682|M.vanbaalenii_PYR-1 RVVYLQHASDPIAWWNPDLLFARPDWLHEPRGYDVSPGMEWIPVVTFLQV
MSMEG_5278|M.smegmatis_MC2_155 RVVYLQHASDPIAWWNTDLLFSKPDWLREPRGYDVSPHTEWIPVVTFLQV
TH_0675|M.thermoresistible__bu RVVYLQHASDPIAWWSPDLLFAEPDWLKEPRGYDVSGRTQWIPVVTFLQV
MAB_1509|M.abscessus_ATCC_1997 RIVYLQHASDPIAWFNPDLILSKPDWLREPRGYDVLPSMEWIPFVTFLQV
Mb1098c|M.bovis_AF2122/97 RVVYLQHASDPIAWWTPRLLFREPDWLREQRGYDVLPQTRWIPVVTFVQV
Rv1069c|M.tuberculosis_H37Rv RVVYLQHASDPIAWWTPRLLFREPDWLREQRGYDVLPQTRWIPVVTFVQV
MMAR_4397|M.marinum_M RVVYLQHASDPIAWWTPDLLFSEPDWLREKRGYDVLPQTRWIPLVTFLQV
MUL_0211|M.ulcerans_Agy99 RVVYLQHASDPIAWWTPDLLFSEPDWLREKRGYDVLPQTRWIPLVTFLQV
MAV_1193|M.avium_104 RVVYLQHASDPIAWWTTDLLFARPDWLKERRGYDVLPETTWIPVVTFLQV
*:************:.. *:: .****:* ** ** ***.***:**
Mflv_2035|M.gilvum_PYR-GCK SADMAVAVDVPDG-----------HGHVYVRNVAN------AWAAILEPP
Mvan_4682|M.vanbaalenii_PYR-1 SADMAVAVNVPDG-----------HGHVYVRNVAD------AWASIMLPP
MSMEG_5278|M.smegmatis_MC2_155 SADMAVAVDVPDG-----------HGHVYVKNVAD------AWAAIMRPP
TH_0675|M.thermoresistible__bu AADMAVATQVPDG-----------HGHRYVHTVAD------AWAAVLQPP
MAB_1509|M.abscessus_ATCC_1997 SADMAVAVDVPDG-----------HGHVYVKAVAD------AWAAVLQPP
Mb1098c|M.bovis_AF2122/97 SADMAVATHVPDG-----------HGHRYVATVAD------GWAAVLSPP
Rv1069c|M.tuberculosis_H37Rv SADMAVATHVPDG-----------HGHRYVATVAD------GWAAVLSPP
MMAR_4397|M.marinum_M SADMAVAVDVPDG-----------HGHRYVSNVAN------GWAAVLSPP
MUL_0211|M.ulcerans_Agy99 SADMAVAVDVPDGMDTATSATSPTAGPRSCRRRAGPPRKPSGYDRCCAPT
MAV_1193|M.avium_104 SADMAVAQNVPDG-----------HGHHYVADVAD------AWAAVLSPP
:****** .**** * *. .: *.
Mflv_2035|M.gilvum_PYR-GCK GWTPEKTEKLRTMLRSDENS-------
Mvan_4682|M.vanbaalenii_PYR-1 GWTQDKTEKLRGLLRSDENS-------
MSMEG_5278|M.smegmatis_MC2_155 GWTPEKTERLRPLLTNNESA-------
TH_0675|M.thermoresistible__bu GWTHEKTERLRPLLHADAKPNEVSPTK
MAB_1509|M.abscessus_ATCC_1997 GWTPEKTQRLRPLLHSGA---------
Mb1098c|M.bovis_AF2122/97 GWTQQKTERLQPLLHANAKPFGS----
Rv1069c|M.tuberculosis_H37Rv GWTQQKTERLQPLLHANAKPFGS----
MMAR_4397|M.marinum_M GWTPEKTERLRPLLRAN----------
MUL_0211|M.ulcerans_Agy99 SGCGVGRRSGRPSIVSR----------
MAV_1193|M.avium_104 GWTPDKTDRLRPLLHANG---------
. : :