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M. thermoresistible (build 8) TH_0674 (echA9)

annotation: POSSIBLE ENOYL-CoA HYDRATASE ECHA9 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
coordinates: 1439148 - 1440200
length: 351

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0674 echA9 - 100% (351) POSSIBLE ENOYL-CoA HYDRATASE ECHA9 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8) TH_4102 - 2e-21 30.19% (212) PUTATIVE short chain enoyl-CoA hydratase
M. thermoresistible (build 8) TH_2638 - 2e-18 30.77% (221) PUTATIVE enoyl-CoA hydratase PaaB

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1100c echA9 1e-145 71.88% (345) enoyl-CoA hydratase
M. gilvum PYR-GCK Mflv_2037 - 1e-145 70.52% (346) enoyl-CoA hydratase
M. tuberculosis H37Rv Rv1071c echA9 1e-145 71.88% (345) enoyl-CoA hydratase
M. leprae Br4923 MLBr_02401 - 1e-143 71.01% (345) 3-hydroxyisobutyryl-CoA hydrolase
M. abscessus ATCC 19977 MAB_1187c - 1e-135 69.82% (338) enoyl-CoA hydratase
M. marinum M MMAR_4395 echA9 1e-148 72.46% (345) enoyl-CoA hydratase EchA9
M. avium 104 MAV_1196 - 1e-145 73.04% (345) enoyl-CoA hydratase
M. smegmatis MC2 155 MSMEG_5276 - 1e-157 76.23% (345) enoyl-CoA hydratase
M. ulcerans Agy99 MUL_0209 echA9 1e-148 72.46% (345) enoyl-CoA hydratase
M. vanbaalenii PYR-1 Mvan_4680 - 1e-147 71.88% (345) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


TH_0674|M.thermoresistible__bu      -----------VTAKNEDVLVNVEGGVGLLTLNRPKAINSLTHGMVTTMA
MSMEG_5276|M.smegmatis_MC2_155      ------------MTENEDILVNVRNGVGILTLNRPKAINSLTEAMVAEIG
Mb1100c|M.bovis_AF2122/97           -----------MTGESHEVLTNVEGGVGFVTLNRPKAINSLNQTMVDLLA
Rv1071c|M.tuberculosis_H37Rv        -----------MTGESHEVLTNVEGGVGFVTLNRPKAINSLNQTMVDLLA
MMAR_4395|M.marinum_M               -----------MTGESDEVLTRVDGGVGFISLNRPKAINSLNQTMVDLLS
MUL_0209|M.ulcerans_Agy99           -----------MTGESDEVLTRVDGGVGFITLNRPKAINSLNQTMVDLLS
MAV_1196|M.avium_104                -----------MTDGSDEVLTQVDGNVGLITLNRPKAINSLNQPMIDALS
MLBr_02401|M.leprae_Br4923          -----------MAGESDEVLARVEAGIGLITLNRPKAINSLNQQMVDALT
MAB_1187c|M.abscessus_ATCC_199      -----------MT---DQIETRVEKGVGLLTLNRPKAINSLTYDMIAAMN
Mflv_2037|M.gilvum_PYR-GCK          MPSVGRRSTLHSVDENEDVLVTVANGIGRITLNRPKAINSLTHPMVTAID
Mvan_4680|M.vanbaalenii_PYR-1       ------------MDENKDVLVTVRNGIGRITLNRPKAINSLTHPMVTDIA
                                                    .:: . *  .:* ::**********.  *:  : 

TH_0674|M.thermoresistible__bu      ERLAAWENDDSVRAVLLTGAGERGLCAGGDVVAIYHSAKADGAEARRFWF
MSMEG_5276|M.smegmatis_MC2_155      KALHAWENDDSVHTVLLTGAGERGLCAGGDVVALYHSAKAGGADARRFWY
Mb1100c|M.bovis_AF2122/97           TVLMSWEHEDAVHAVVLSGAGERGLCAGGDVVAVYHSARKDGVEARRFWR
Rv1071c|M.tuberculosis_H37Rv        TVLMSWEHEDAVHAVVLSGAGERGLCAGGDVVAVYHSARKDGVEARRFWR
MMAR_4395|M.marinum_M               TVLTRWERDGEVRAVVVSGAGERGLCAGGDVVAVYHSARKDGAEARRFWR
MUL_0209|M.ulcerans_Agy99           TVFTRWERDGEVRAVVVSGAGERGLCAGGDVVAVYHSARKDGAEARRFWR
MAV_1196|M.avium_104                AVLTDWARDDKVRAVLLSGAGERGLCAGGDVVSIYHSARKDGVEARRFWR
MLBr_02401|M.leprae_Br4923          AILTSWADDDAVRAVVLSGAGERGLCAGGDVVAIYHSALKDGVEARRFWR
MAB_1187c|M.abscessus_ATCC_199      AVLAEWEADDAVRVVVLSGAGERGLCAGGDVVAVHDSAKIDGVAARRFFR
Mflv_2037|M.gilvum_PYR-GCK          ATLKTWQTDDSVTAVLVTGAGERGLCAGGDVVAIYHDAKVGGALTRRFWH
Mvan_4680|M.vanbaalenii_PYR-1       QALKAWETDDAVTAVIVSGAGDRGLCAGGDVVAIYHDARAGGSESRRFWH
                                      :  *  :. * .*:::***:**********:::..*  .*  :***: 

TH_0674|M.thermoresistible__bu      DEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVTDTTKMAMPE
MSMEG_5276|M.smegmatis_MC2_155      DEYLVNAYIGNYPKPYVAVMDGIVMGGGVGVAGHGSIRVVTDTTKMAMPE
Mb1100c|M.bovis_AF2122/97           HEYLLNALIGRFAKPYVALMDGIVMGGGVGVSAHANTRVVTDTSKVAMPE
Rv1071c|M.tuberculosis_H37Rv        HEYLLNALIGRFAKPYVALMDGIVMGGGVGVSAHANTRVVTDTSKVAMPE
MMAR_4395|M.marinum_M               DEYLMNGQIGRFSKPYVALMDGIVMGGGVGVSAHGDIRVVTDTSKVAMPE
MUL_0209|M.ulcerans_Agy99           DEYLMNGQIGRFSKPYVALMDGIVMGGGVGVSAHGDIRVVTDTSKVAMPE
MAV_1196|M.avium_104                DEYQLNAQISEFAKPYVAVMDGIVMGGGVGVSAHANTRVVTDTSKVAMPE
MLBr_02401|M.leprae_Br4923          SEYLLNSQIARFPKPYVSLMDGIVMGGGVGIGAHANTRVVTDTSQVAMPE
MAB_1187c|M.abscessus_ATCC_199      DEYVLNAQIARFPKPYVALMDGIVMGGGVGVGGHANIRIVTDTSKVAMPE
Mflv_2037|M.gilvum_PYR-GCK          DEYLLNSYIGRYPKPYVAIMNGITMGGGVGISAHGSVRVVTETTKMAMPE
Mvan_4680|M.vanbaalenii_PYR-1       DEYLLNAYIGRYPKPYVAIMNGITMGGGVGISAHGSVRVVTETTKMAMPE
                                     ** :*. *..:.****::*:**.******:..*.. *:**:*:::****

TH_0674|M.thermoresistible__bu      VGIGFIPDVGGTYLLSRAPGKLGLHAALTGAPFSGADAIVMGFADHYVPH
MSMEG_5276|M.smegmatis_MC2_155      VGIGFVPDVGGTYLLSRAPGALGLHAALTGAPFSGADAIAMGFADHYVPH
Mb1100c|M.bovis_AF2122/97           VGIGFIPDVGGVYLLSRAPGALGLHAALTGAPFSGADAIALGFADHFVPH
Rv1071c|M.tuberculosis_H37Rv        VGIGFIPDVGGVYLLSRAPGALGLHAALTGAPFSGADAIALGFADHFVPH
MMAR_4395|M.marinum_M               VGIGFIPDVGGAYLLSRAPGALGLHAALTGAPFSGADAIALGFADHFVPH
MUL_0209|M.ulcerans_Agy99           VGIGFIPDVGGAYLLSRAPGALGLHTALTGAPFSGADAIALGFADHFVPH
MAV_1196|M.avium_104                VGIGFIPDVGGVYLLSRAPGGLGLHAALTGAPFSGADAIAMGFADHYVPH
MLBr_02401|M.leprae_Br4923          VGIGFIPDVGGTYLLSRAPGALGLHVALTGAPFSGADAIELGFADHYVPH
MAB_1187c|M.abscessus_ATCC_199      VGIGFIPDVGGTYLLSRAPGQLGLHAALTGAPFSGADAIALGFADHYVPH
Mflv_2037|M.gilvum_PYR-GCK          VGIGFIPDVGGTFILSRTPGLLGVHAAMTGAPFSGADAIEMGFADHFVPQ
Mvan_4680|M.vanbaalenii_PYR-1       VGIGFIPDVGGTFILSRTPGLLGVHAALTGAAFSGADAIAMGFADHFVPQ
                                    *****:*****.::***:** **:*.*:***.******* :*****:**:

TH_0674|M.thermoresistible__bu      DKIDEFTRAVIADGVDAALAAHAQEPPASPLAEQRSWIDECYTGDTVADI
MSMEG_5276|M.smegmatis_MC2_155      DKLADFIESVVAEGVEQALSAHAVEPPASALMEQRAWIDESYAGATVADI
Mb1100c|M.bovis_AF2122/97           GDLDAFTQKIVTGGVESALAAHAVEPPPSTLAAQRDWIDECYAGDSVADI
Rv1071c|M.tuberculosis_H37Rv        GDLDAFTQKIVTGGVESALAAHAVEPPPSTLAAQRDWIDECYAGDSVADI
MMAR_4395|M.marinum_M               AELGAFSAAIASDGIESALAHHAVEPPPSGLAAQRGWIDECYAGDTVADI
MUL_0209|M.ulcerans_Agy99           AELGAFSAAIASDGIESALAHHAVEPPPSGLAAQRGWIDECYAGDTVADI
MAV_1196|M.avium_104                ADVEAFRRAVVADGVESALAKYAVEPPPGELAAQRDWIDECYAGQTVEDI
MLBr_02401|M.leprae_Br4923          SDLNAFTRAVVTDGVNSALAGYAIEPPPSYLAAQRDWIDECYVGETVKDI
MAB_1187c|M.abscessus_ATCC_199      DRLEKFTKAIIDSDIATALAVHGTNAPSSDLLAQRNWIDECYGGESVADI
Mflv_2037|M.gilvum_PYR-GCK          DQLEAFVAAVEADGVDAAVAAHAQQPPPSPLSAHREWIDSCYAAGTADDI
Mvan_4680|M.vanbaalenii_PYR-1       DRLAAFADAIEADGVDAAVAAFAQEPPPSALLAQRDWIDHCYAGETVADI
                                      :  *   :   .:  *:: .. :.*.. *  :* *** .* . :. **

TH_0674|M.thermoresistible__bu      IAALRAHDAPAAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTLRQE
MSMEG_5276|M.smegmatis_MC2_155      LAALQNHDAPEARAAADLIATRSPVALAVTLEAVRRAEKLDTLEEALRQE
Mb1100c|M.bovis_AF2122/97           VAALRKQGGEPAVNASDLIASRSPIALSVTLQAVRRAAKLDTLEDVLIQD
Rv1071c|M.tuberculosis_H37Rv        VAALRKQGGEPAVNASDLIASRSPIALSVTLQAVRRAAKLDTLEDVLIQD
MMAR_4395|M.marinum_M               IAALRGHDAGPANDAANVIASRSPIALSVTLEAVRRAAKLETLEDVLVQD
MUL_0209|M.ulcerans_Agy99           IAALRGHDAGPANDAADVIASRSPIALSVTLEAVRRAAKLETLEDVLVQD
MAV_1196|M.avium_104                VAALRAHGAGPAHDAADLIATRSPIALSVTLAAVRRAADLPTLKDVLVQD
MLBr_02401|M.leprae_Br4923          ITALRGHDAEPAEGAFNLIVSRSPVALSVTLEAMRRAAKLETLTDVLTQD
MAB_1187c|M.abscessus_ATCC_199      VAALQARGDERARAAADQILTRSPIALSVTLAAVRRARELPSLEAVLTQE
Mflv_2037|M.gilvum_PYR-GCK          VSALRAHGAQPATDAADLIASRSPVAVSVALEAVRRAAGLATLEDVLRQE
Mvan_4680|M.vanbaalenii_PYR-1       VVALRGHDAEPAIDAAELIESRSPVAASVTLEAVRRAAKLDTLEDVLRQE
                                    : **: :.   *  * : * :***:* :*:* ::***  * :*  .* *:

TH_0674|M.thermoresistible__bu      YRVSCASLKSHDLVEGIRAQLVDKDRNPKWRPATLAEVTEADVEAYFAPV
MSMEG_5276|M.smegmatis_MC2_155      YRISSAAVRSHDFVEGIRAQLVDKDRNPKWSPASIADVTQADIDAYFVPA
Mb1100c|M.bovis_AF2122/97           YRVSSASLRSHDLVEGIRAQLIDKDRNPNWSPATLDAITAADIEAYFEPV
Rv1071c|M.tuberculosis_H37Rv        YRVSSASLRSHDLVEGIRAQLIDKDRNPNWSPATLDAITAADIEAYFEPV
MMAR_4395|M.marinum_M               YRVSSASLRSHDLVEGIRAQLIDKDRNPKWSPATFAEITESDVAAYFAPV
MUL_0209|M.ulcerans_Agy99           YRVSSASLRSHDLVEGIRAQLIDKDRNPKWSPATFAEITESDVAAYFAPV
MAV_1196|M.avium_104                YRVSSASLRSHDLVEGIRAQLIDKDRNPQWSPARLADVTAADVEAYFAPV
MLBr_02401|M.leprae_Br4923          YRVSSASLHSHDLVEGIRAQLVHKDRNPQWAPTTLAEVTAADICGYFEPV
MAB_1187c|M.abscessus_ATCC_199      YRVSSQSVRSHDLVEGIRAQLVDKDRNPQWVPKTLAEVTKADVEEFFQPV
Mflv_2037|M.gilvum_PYR-GCK          FRTSIAALRSHDLVEGIRALLIDKDKNPQWSPATLADVTAADIEAYFVSA
Mvan_4680|M.vanbaalenii_PYR-1       FRTSVASLRSHDLVEGIRALLIDKDKNPQWSPASLSTVTPADIEAYFAPA
                                    :* *  :::***:****** *:.**:**:* *  :  :* :*:  :* ..

TH_0674|M.thermoresistible__bu      DPELTFEGETQ
MSMEG_5276|M.smegmatis_MC2_155      DPELEFEKEN-
Mb1100c|M.bovis_AF2122/97           DDDLSF-----
Rv1071c|M.tuberculosis_H37Rv        DDDLSF-----
MMAR_4395|M.marinum_M               DDDLSF-----
MUL_0209|M.ulcerans_Agy99           DDDLSF-----
MAV_1196|M.avium_104                DDDLSF-----
MLBr_02401|M.leprae_Br4923          DDDLSF-----
MAB_1187c|M.abscessus_ATCC_199      SDDLEWP----
Mflv_2037|M.gilvum_PYR-GCK          DPDINFEEQS-
Mvan_4680|M.vanbaalenii_PYR-1       DPDLTFDEE--
                                    . :: :

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0674	echA9	-	100% (351)	POSSIBLE ENOYL-CoA HYDRATASE ECHA9 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE)
M. thermoresistible (build 8)	TH_4102	-	2e-21	30.19% (212)	PUTATIVE short chain enoyl-CoA hydratase
M. thermoresistible (build 8)	TH_2638	-	2e-18	30.77% (221)	PUTATIVE enoyl-CoA hydratase PaaB