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M. thermoresistible (build 8) TH_0600 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1273301 - 1274230
length: 310

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0600-100% (310)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_0869-5e-0535.14% (111) heparin-binding hemagglutinin
M. thermoresistible (build 8)TH_2451-9e-0543.40% (53) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0962c-1e-13082.84% (268) hypothetical protein Mb0962c
M. gilvum PYR-GCKMflv_1826-1e-14880.43% (327) Ku domain-containing protein
M. tuberculosis H37RvRv0937c-1e-13082.84% (268) hypothetical protein Rv0937c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1032c-1e-12279.10% (268) hypothetical protein MAB_1032c
M. marinum MMMAR_4575-1e-14081.58% (304) hypothetical protein MMAR_4575
M. avium 104MAV_1050-1e-14281.61% (310) Ku protein
M. smegmatis MC2 155MSMEG_5580-1e-14783.92% (311) Ku protein
M. ulcerans Agy99MUL_4436-1e-13880.26% (304) hypothetical protein MUL_4436
M. vanbaalenii PYR-1Mvan_4917-1e-14481.61% (310) Ku domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0962c|M.bovis_AF2122/97           ----------MRAIWTGSIAFGLVNVPVKVYSATADHDIRFHQVHAKDNG
Rv0937c|M.tuberculosis_H37Rv        ----------MRAIWTGSIAFGLVNVPVKVYSATADHDIRFHQVHAKDNG
MMAR_4575|M.marinum_M               ----------MRSIWKGSIAFGLVNVPVKVYSATQDHDIKFHQVHAKDNG
MUL_4436|M.ulcerans_Agy99           ----------MRSIWKGSIAFGLVNVPVKVYSATQDHDIKFHQVHAKDNG
MAV_1050|M.avium_104                ----------MRSIWKGSIAFGLVNVPVKVYSATEDHDIKFHQVHAKDNG
Mflv_1826|M.gilvum_PYR-GCK          ----------MRSIWKGSIAFGLVNVPVKVYSATEDHDIKFHQVHEKDNG
Mvan_4917|M.vanbaalenii_PYR-1       ----------MRSIWKGSIAFGLVNVPVKVYSATEDHDIKFHQVHDKDNG
TH_0600|M.thermoresistible__bu      ----------MRSIWKGSIAFGLVNVPVKVYSATQDHDVKFHQVHAKDNG
MSMEG_5580|M.smegmatis_MC2_155      MNRAVRHTGLMRSIWKGSIAFGLVNVPVKVYSATEDHDIKFHQVHAKDNG
MAB_1032c|M.abscessus_ATCC_199      ----------MRSIWKGSLAFGLVNVPVKVYSATEDHDLKFHQVHNKDNG
                                              **:**.**:*************** ***::***** ****

Mb0962c|M.bovis_AF2122/97           RIRYKRVCEACGEVVDYRDLARAYESGDGQMVAITDDDIASLPEERSREI
Rv0937c|M.tuberculosis_H37Rv        RIRYKRVCEACGEVVDYRDLARAYESGDGQMVAITDDDIASLPEERSREI
MMAR_4575|M.marinum_M               RIRYKRVCEVCGEVVEYSDLARAFESDDGQMVIINDDDLATLPEDRSREI
MUL_4436|M.ulcerans_Agy99           RIRYKRVCEVCGEVVEYSDLARAFESDDGQMVIINDDDLATLPEDRSREI
MAV_1050|M.avium_104                RIRYQRVCELDGEVVEYRDIARAYESDDGQMVIITDDDIATLPEERSREI
Mflv_1826|M.gilvum_PYR-GCK          RIRYNRVCEVCGEVVEYRDIAKAYESDDGQTVIITDDDISTLPEERSREI
Mvan_4917|M.vanbaalenii_PYR-1       RIRYKRVCEVCGEVVEYRDIAKAYESDDGQTVIITDDDISTLPEERSREI
TH_0600|M.thermoresistible__bu      RIRYKRVCEVCGEVVEYRDIARAYESDDGQMVVITDEDLATLPEERSREI
MSMEG_5580|M.smegmatis_MC2_155      RIRYKRVCEVCGEVVEYRDINKAFESDDGQMVVITDEDIATLPEERSREI
MAB_1032c|M.abscessus_ATCC_199      RIRYKRTCEECGEVVEFRDINKAYEAEDGRTVVITDEDLASLPAESSREI
                                    ****:*.**  ****:: *: :*:*: **: * *.*:*:::** : ****

Mb0962c|M.bovis_AF2122/97           EVLEFVPAADVDPMMFDRSYFLEPDSKSSKSYVLLAKTLAETDRMAIVHF
Rv0937c|M.tuberculosis_H37Rv        EVLEFVPAADVDPMMFDRSYFLEPDSKSSKSYVLLAKTLAETDRMAIVHF
MMAR_4575|M.marinum_M               EVLEFVPAEEVDPMMIDRSYFLEPDSKSSKSYVLLAKTLAETERMAIVHF
MUL_4436|M.ulcerans_Agy99           EVLEFVPAEEVDPMMIDRSYFLEPDSESSKSYVLLAKTLAETERMAIVHF
MAV_1050|M.avium_104                EVLEFVPANEVDPMLFDRSYFLEPDSKSSKSYVLLAKTLAETDRMAIVHF
Mflv_1826|M.gilvum_PYR-GCK          EVLEFVPAADLDPLMYDRSYFLEPEGKSTKSYVLLAKTLAETDRVAIVNF
Mvan_4917|M.vanbaalenii_PYR-1       EVLEFVPAGDLDPLMYDRSYFLEPDGKSSKSYVLLAKTLMDTDRVAIVNF
TH_0600|M.thermoresistible__bu      EVVEFVPAEQLDPMMYDRSYFLEPDSKSSKSYVLLAKTLAQTDRIAIVHF
MSMEG_5580|M.smegmatis_MC2_155      EVVEFIPAEQLDPLMYDKSYFLEPDSKSSKSYVLLAKTLAETDRIAIVHF
MAB_1032c|M.abscessus_ATCC_199      EVLEFIPAAELDPLMYDKSYYLEPDSKSSKSYVLLAQTLAQTDRVAIVHF
                                    **:**:** ::**:: *:**:***:.:*:*******:** :*:*:***:*

Mb0962c|M.bovis_AF2122/97           TLRNKTRLAALRVKDFGKREVMMVHTLLWPDEIRDPDFPVLDQKVEIKPA
Rv0937c|M.tuberculosis_H37Rv        TLRNKTRLAALRVKDFGKREVMMVHTLLWPDEIRDPDFPVLDQKVEIKPA
MMAR_4575|M.marinum_M               TLRSKTRLAALRVKDFGKREVMVVHTLLWPDEIRDPDFPVLDKEVEIKPA
MUL_4436|M.ulcerans_Agy99           TLRSKTRLAALRAKDFGKREVMVVHTLLWLDEIRDPDFPVLDKEVEIKPA
MAV_1050|M.avium_104                TLRNKTRLAALRVKDFGKRDVMVIHTLLWPDEIRDPDFPILDKKVEIKPA
Mflv_1826|M.gilvum_PYR-GCK          ALRNKTRLAALRVKDFSKRDVMVIHTLLWPDEIRDPDFPVLDKDVDVKPA
Mvan_4917|M.vanbaalenii_PYR-1       ALRNKTRLAALRVKDFSKRDVMMIHTLLWPDEIRDPDFPVLDKKVDVKPA
TH_0600|M.thermoresistible__bu      SLRNKTRLGALRVKDFSKRDVMMIHTLLWPDEIRDPDFPVLDKEVEIKPA
MSMEG_5580|M.smegmatis_MC2_155      SLRNKSRLAALRVKDFSKRDVMMIHTLLWPDEIRDPDFPILDKEVQIKPA
MAB_1032c|M.abscessus_ATCC_199      ALRNKTRLAALRVKDFGERQVMIIHTLLWPDEIREPDFPVLDQEVKIKPA
                                    :**.*:**.***.***.:*:**::***** ****:****:**:.*.:***

Mb0962c|M.bovis_AF2122/97           ELKMAGQVVDSMADDFNPDRYHDTYQEQLQELIDTKLEGGQAFTAEDQPR
Rv0937c|M.tuberculosis_H37Rv        ELKMAGQVVDSMADDFNPDRYHDTYQEQLQELIDTKLEGGQAFTAEDQPR
MMAR_4575|M.marinum_M               ELKMAGQVVESMADDFNPDRYRDTYQEQLQELIDAKLEGGEAFTAEEQPA
MUL_4436|M.ulcerans_Agy99           ELKMAGQVVESMADDFNPDRYRDTYQEQLQELIDAKLEGGEAFTAEEQPA
MAV_1050|M.avium_104                ELKMAGQVVESMAEDFNPDRYHDDYQEQLHELVQAKLEGGEAFTTEEQPK
Mflv_1826|M.gilvum_PYR-GCK          ELKMASQVVDSMTDDFNPDRYHDDYQEQLRELVQAKLEGGEAFTTEEQPQ
Mvan_4917|M.vanbaalenii_PYR-1       ELKMASQVVDSMTDDFNPDRYHDDYQEQLHELIQAKLEGGEAFTTEEQPQ
TH_0600|M.thermoresistible__bu      ELKMAAQVVDSMTDDFHPDQYRDTYQEQLQELVQAKLEGGEAFTTEEQPT
MSMEG_5580|M.smegmatis_MC2_155      ELKMAGQVVESMTDDFKPDLYHDDYQEQLRELVQAKLEGGEAFSVEEQPA
MAB_1032c|M.abscessus_ATCC_199      ELAMAGQVVESMADDFDPSRYNDTYQSQLLEMVEAKLEGGEAFTKEEAPT
                                    ** **.***:**::**.*. *.* **.** *::::*****:**: *: * 

Mb0962c|M.bovis_AF2122/97           LLDE-PEDVSDLLAKLEASVKARS--------------------------
Rv0937c|M.tuberculosis_H37Rv        LLDE-PEDVSDLLAKLEASVKARS--------------------------
MMAR_4575|M.marinum_M               ELDE-TEDVSDLLAKLEASVKARSG-------------------------
MUL_4436|M.ulcerans_Agy99           ELDE-TEDVSDLLAKLEASVKARSG-------------------------
MAV_1050|M.avium_104                QLDE-TEDVSDLLAKLEASVKARSG-------------------------
Mflv_1826|M.gilvum_PYR-GCK          ELDE-SEDVSDLLAKLEASVKARKAQSSGKSSDSDDSDDSDDSDDSDDSD
Mvan_4917|M.vanbaalenii_PYR-1       ELDE-TEDVSDLLAKLEASVKARKAQGT----------------------
TH_0600|M.thermoresistible__bu      ELDE-TEDVSDLLAKLEASVKARRSGGSSKSS------------------
MSMEG_5580|M.smegmatis_MC2_155      ELDEGTEDVSDLLAKLEASVKARKGGKSDSKDDSDS------------ES
MAB_1032c|M.abscessus_ATCC_199      ELDA--TDVSDLLAKLEASVKKRQ--------------------------
                                     **    ************** *                           

Mb0962c|M.bovis_AF2122/97           ---KANSNVPTPP---------------------------
Rv0937c|M.tuberculosis_H37Rv        ---KANSNVPTPP---------------------------
MMAR_4575|M.marinum_M               -DGKSAAKKSTAEKAPAKKARAKQAAKS------------
MUL_4436|M.ulcerans_Agy99           -DGKSAAKKSTAERAPAKKARAKQAAKS------------
MAV_1050|M.avium_104                -DGKAPARKSPAKKTAAKKAPAKKGAAKKAPAKKAASRS-
Mflv_1826|M.gilvum_PYR-GCK          EKDDKPAKKVPAKKSAAKKAPAKK-AAKKAPAKKAAAKKG
Mvan_4917|M.vanbaalenii_PYR-1       QKDEPAAEKPAAKKPAAKKSPAKKTAAKKAPAKKAPAKK-
TH_0600|M.thermoresistible__bu      DADDGDKPKKSPAKKAAKKAPAKKAARKASAKKTAPKK--
MSMEG_5580|M.smegmatis_MC2_155      DSKESKSDSKPAKKAPAKKAAAKKSTAKKAPAKKAAAKKS
MAB_1032c|M.abscessus_ATCC_199      ------AEKASTN---------------------------
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