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M. thermoresistible (build 8) TH_0544 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1165006 - 1165404
length: 133

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0544-100% (133)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1254-1e-4372.88% (118) hypothetical protein Mb1254
M. gilvum PYR-GCKMflv_2201-2e-4770.77% (130) hypothetical protein Mflv_2201
M. tuberculosis H37RvRv1222-1e-4372.88% (118) hypothetical protein Rv1222
M. leprae Br4923MLBr_01077-2e-4366.39% (122) hypothetical protein MLBr_01077
M. abscessus ATCC 19977MAB_1363-1e-3665.81% (117) hypothetical protein MAB_1363
M. marinum MMMAR_4215-6e-4767.16% (134) hypothetical protein MMAR_4215
M. avium 104MAV_1365-7e-4466.67% (132) RNA polymerase sigma-70 factor
M. smegmatis MC2 155MSMEG_5071-7e-5474.24% (132) hypothetical protein MSMEG_5071
M. ulcerans Agy99MUL_4518-4e-4767.16% (134) hypothetical protein MUL_4518
M. vanbaalenii PYR-1Mvan_4495-2e-4872.31% (130) hypothetical protein Mvan_4495

CLUSTAL 2.0.9 multiple sequence alignment


Mb1254|M.bovis_AF2122/97            --------------------------------------------------
Rv1222|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01077|M.leprae_Br4923          --------------------------------------------------
MMAR_4215|M.marinum_M               --------------------------------------------------
MUL_4518|M.ulcerans_Agy99           --------------------------------------------------
MAV_1365|M.avium_104                MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHD
TH_0544|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5071|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2201|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4495|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1363|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1254|M.bovis_AF2122/97            --------------------------------------------------
Rv1222|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01077|M.leprae_Br4923          --------------------------------------------------
MMAR_4215|M.marinum_M               --------------------------------------------------
MUL_4518|M.ulcerans_Agy99           --------------------------------------------------
MAV_1365|M.avium_104                PSADGWAEPSDGLQGTAVFDATGDKTAMPSWDELVRQHADRVYRLAYRLS
TH_0544|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5071|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2201|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4495|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1363|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1254|M.bovis_AF2122/97            --------------------------------------------------
Rv1222|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01077|M.leprae_Br4923          --------------------------------------------------
MMAR_4215|M.marinum_M               --------------------------------------------------
MUL_4518|M.ulcerans_Agy99           --------------------------------------------------
MAV_1365|M.avium_104                GNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRSR
TH_0544|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5071|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2201|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4495|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1363|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1254|M.bovis_AF2122/97            --------------------------------------------------
Rv1222|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01077|M.leprae_Br4923          --------------------------------------------------
MMAR_4215|M.marinum_M               --------------------------------------------------
MUL_4518|M.ulcerans_Agy99           --------------------------------------------------
MAV_1365|M.avium_104                IRMEALPEDYERVPADEPNPEEIYHDSRLGPDLQAALDSLPPEFRAAVVL
TH_0544|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5071|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2201|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4495|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1363|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1254|M.bovis_AF2122/97            --------------------------------------------------
Rv1222|M.tuberculosis_H37Rv         --------------------------------------------------
MLBr_01077|M.leprae_Br4923          --------------------------------------------------
MMAR_4215|M.marinum_M               --------------------------------------------------
MUL_4518|M.ulcerans_Agy99           --------------------------------------------------
MAV_1365|M.avium_104                CDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAHPDHDALRASL
TH_0544|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5071|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_2201|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4495|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_1363|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb1254|M.bovis_AF2122/97            ------------------------------------------------MA
Rv1222|M.tuberculosis_H37Rv         ------------------------------------------------MA
MLBr_01077|M.leprae_Br4923          -----------------------------------------------MMA
MMAR_4215|M.marinum_M               ------------------------------------------------MA
MUL_4518|M.ulcerans_Agy99           ------------------------------------------------MA
MAV_1365|M.avium_104                GVVSARPANVRAAIQRLCGLGLGIGRPVALHSKKANKAAIRMNGKELAMP
TH_0544|M.thermoresistible__bu      ------------------------------------------------MA
MSMEG_5071|M.smegmatis_MC2_155      ------------------------------------------------MA
Mflv_2201|M.gilvum_PYR-GCK          ------------------------------------------MERGAVVF
Mvan_4495|M.vanbaalenii_PYR-1       -----------------------------------------------MVF
MAB_1363|M.abscessus_ATCC_1997      ------------------------------------------------MV
                                                                                    : 

Mb1254|M.bovis_AF2122/97            DPGSVGHVFRRAFS------WLPAQFASQSDAPVGAPRQFRSTEHLSIEA
Rv1222|M.tuberculosis_H37Rv         DPGSVGHVFRRAFS------WLPAQFASQSDAPVGAPRQFRSTEHLSIEA
MLBr_01077|M.leprae_Br4923          DRG---QVFRRVFS------WLPAQFASQNDAPVGAPRRFGSTEHLSVEA
MMAR_4215|M.marinum_M               DRG---HVFRRAFS------WLPAQFASQSDAPVGAPRRFRSTEHLSIEA
MUL_4518|M.ulcerans_Agy99           DRG---HVFRRAFS------WLPAQFASQSDAPVGAPRRFRSTEHLSIEA
MAV_1365|M.avium_104                DRG---HVFRRAFS------WLPAQFASQSDAPVGAPRQFGSTEHLSVEA
TH_0544|M.thermoresistible__bu      EPG---HLFRRAFS------WLPAQFAPQNDAPVGAPRQFGSTEHLSTEA
MSMEG_5071|M.smegmatis_MC2_155      DPG---HVFRRAFS------WLPSQFASQSDAPVGAPRQFGSTEHLSVEA
Mflv_2201|M.gilvum_PYR-GCK          DPGH---AFRRAFS------WLP----SQSDSPVG-PRQFGSTEHLSTEA
Mvan_4495|M.vanbaalenii_PYR-1       DPGH---AFRRAFS------WLPSQLASQSDDPVG-PRQFGSTEHLSIEA
MAB_1363|M.abscessus_ATCC_1997      DSG----SFRRAFSSFSSFSRLPSPFASQSGAPVGAPRQFGSTEHLSTEA
                                    : *     ***.**       **    .*.. *** **:* ****** **

Mb1254|M.bovis_AF2122/97            IAAFVDGELRMNAHLRAAHHLSLCAQCAAEVDDQSRARAALRDSHPIRIP
Rv1222|M.tuberculosis_H37Rv         IAAFVDGELRMNAHLRAAHHLSLCAQCAAEVDDQSRARAALRDSHPIRIP
MLBr_01077|M.leprae_Br4923          IAAFVDGELRMNAHLRAAHHISLCAQCAAEVDDQSRTRAALRDSHPIRIP
MMAR_4215|M.marinum_M               IAAFVDGELRMNAHLRAAHHLSMCPQCAAEVEDHTRARAALRDSHPIRIP
MUL_4518|M.ulcerans_Agy99           IAAFVDGELRMNAHLRAAHHLSMCPQCAAEVEDHTRARAALRDSHPIRIP
MAV_1365|M.avium_104                IAAFVDGELRMNAHLRAAHHLSQCAQCAAEVDDQSRARAALRDSRPIRIP
TH_0544|M.thermoresistible__bu      VAAFVDGELGMTAHLRAAHHLSLCPQCAAEVDAQAQARAALRESRPVDVP
MSMEG_5071|M.smegmatis_MC2_155      IAAFVDGELRMSAHLRAAHHLSLCPECAAEVDAQSQARTALRESCPIAIP
Mflv_2201|M.gilvum_PYR-GCK          IAAFADGELRMTAHLRAAHHLSLCSECAQEVDAQRQAREALRDSCPVDIP
Mvan_4495|M.vanbaalenii_PYR-1       VAAFVDGELRMSAHLRAAHHLSLCPECALEVDAQRQAREALRESRPVAMP
MAB_1363|M.abscessus_ATCC_1997      IAAFVDGELRMSAHLRAAHHLSMCAECALEIDAQRQARTALRDSGAIRVP
                                    :***.**** *.********:* *.:** *:: : ::* ***:* .: :*

Mb1254|M.bovis_AF2122/97            STLLGLLSEIPRCPPEGPSKGSSGGSSQGPPDGAAAGFGDRFADGDGG--
Rv1222|M.tuberculosis_H37Rv         STLLGLLSEIPRCPPEGPSKGSSGGSSQGPPDGAAAGFGDRFADGDGG--
MLBr_01077|M.leprae_Br4923          STLFGLLTAIPRCSPDYTSP-----VSEPFSEGSVS---DRFVDGVAR--
MMAR_4215|M.marinum_M               TALLGMLSEIPHHP------------SEGAPEDTTG-LADSFAERQAR--
MUL_4518|M.ulcerans_Agy99           TALLGMLSEIPHHP------------SEGAPEDTTG-LADSFAERQAR--
MAV_1365|M.avium_104                ANLLGMLAEIPYESP-------------DAP--------DRLADRDAR--
TH_0544|M.thermoresistible__bu      NSLWGLLSEIPNRT------------SATTPEDPKP---PPFADWQPR--
MSMEG_5071|M.smegmatis_MC2_155      NSLLGMLSQIPHRTP------------EVTPDVSEQ---AKFADDPTR--
Mflv_2201|M.gilvum_PYR-GCK          SSLLGLLSQIPNRTPVDAQ--------EPPES-------PQLADGPPR--
Mvan_4495|M.vanbaalenii_PYR-1       SSLLGLLSQIPNHTPVEAP--------EPADS-------PQLADGAQR--
MAB_1363|M.abscessus_ATCC_1997      GSLLGLLSQIP-HIPHDVA--------PPQPSAHEGELPPALGGDAVRPD
                                      * *:*: **                              :        

Mb1254|M.bovis_AF2122/97            --NRGRQSRVRR
Rv1222|M.tuberculosis_H37Rv         --NRGRQSRVRR
MLBr_01077|M.leprae_Br4923          --EQGKR-----
MMAR_4215|M.marinum_M               --DQRKRR----
MUL_4518|M.ulcerans_Agy99           --DQRKRR----
MAV_1365|M.avium_104                --DRRRRP----
TH_0544|M.thermoresistible__bu      --GWRKRR----
MSMEG_5071|M.smegmatis_MC2_155      --GRRKRR----
Mflv_2201|M.gilvum_PYR-GCK          --ARRKRR----
Mvan_4495|M.vanbaalenii_PYR-1       --SRRKRR----
MAB_1363|M.abscessus_ATCC_1997      SRARRKRR----
                                         ::