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M. thermoresistible (build 8) TH_0500 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1073732 - 1074715
length: 328

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0500-100% (328)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1858-4e-0925.00% (344) DeoR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2122c-1e-12571.12% (322) hypothetical protein Mb2122c
M. gilvum PYR-GCKMflv_3092-1e-14478.95% (323) transcriptional regulator-like protein
M. tuberculosis H37RvRv2095c-1e-12671.43% (322) hypothetical protein Rv2095c
M. leprae Br4923MLBr_01330-1e-12269.02% (326) putative DNA-binding protein
M. abscessus ATCC 19977MAB_2186-1e-11967.70% (322) hypothetical protein MAB_2186
M. marinum MMMAR_3081-1e-12872.41% (319) hypothetical protein MMAR_3081
M. avium 104MAV_2408-1e-13173.29% (322) hypothetical protein MAV_2408
M. smegmatis MC2 155MSMEG_3888-1e-12872.64% (318) hypothetical protein MSMEG_3888
M. ulcerans Agy99MUL_2327-1e-12872.41% (319) hypothetical protein MUL_2327
M. vanbaalenii PYR-1Mvan_3443-1e-14781.50% (319) transcriptional regulator-like protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2122c|M.bovis_AF2122/97           MSALSTRLVRLLNMVPYFQANPRITRAEAAAELGVTAKQLEEDLNQLWMC
Rv2095c|M.tuberculosis_H37Rv        MSALSTRLVRLLNMVPYFQANPRITRAEAAAELGVTAKQLEEDLNQLWMC
MMAR_3081|M.marinum_M               MSPVSTRLVRLLNMVPYFQANPRITRVEAAAELGVSAKQLEEDLNQLWMC
MUL_2327|M.ulcerans_Agy99           MSPVSTRLVRLLNMVPYFQANPRITRVEAAAELGVSAKQLEEDLNQLWMC
MAV_2408|M.avium_104                MTPISTRLVRLLNMVPYFQANPRVTRAKAAADLGVSAKQLEEDLNQLWMC
MLBr_01330|M.leprae_Br4923          MTQLSTRLVRLLNMVPYFQANPRITRAEAAADLGVSAKQLDQDFNQLWVC
Mflv_3092|M.gilvum_PYR-GCK          MTAISARLVRLLNMVPYFQANPRITYTEAAEDLGVSVKQLREDLNQLWMC
Mvan_3443|M.vanbaalenii_PYR-1       MTAVSARLVRLLNMVPYFQANPRITYAEAASDLGVSVKQLREDLNQLWMC
TH_0500|M.thermoresistible__bu      MSKASTRLVRLLNMVPYFQANPRITFAEAASDLGVSVKQLREDLTQLWMC
MSMEG_3888|M.smegmatis_MC2_155      MSQVSTRLVRLLNMVPYFQANPKVTRAEAAAALGVTGKQLDADLDQLWMC
MAB_2186|M.abscessus_ATCC_1997      MTELSNRLTRLLNMVPYFQANPGISAAEAAADLGVTTKQLMADLNQLWMC
                                    *:  * **.************* :: .:**  ***: ***  *: ***:*

Mb2122c|M.bovis_AF2122/97           GLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALA
Rv2095c|M.tuberculosis_H37Rv        GLPGYSPGDLIDFEFCGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALA
MMAR_3081|M.marinum_M               GLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALA
MUL_2327|M.ulcerans_Agy99           GLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLKLTSPEATGLLVALRALA
MAV_2408|M.avium_104                GLPGYFPGDLIDFEFSGDTIEVTFSAGIDRPLRLTSPEATGLLVALRALA
MLBr_01330|M.leprae_Br4923          GLPGYGPGDLIDFEFSGDTIEVTFSAGIDRPLQLTSPEAIGLLVALRALA
Mflv_3092|M.gilvum_PYR-GCK          GLPGYGPGDLIDFEFSGDTIEVTFSAGIDHPLRLTSPEATGVLVALRSLV
Mvan_3443|M.vanbaalenii_PYR-1       GLPGYGPGDLIDFEFSGDTIEVTFSAGIDHPLRLTSPEATGVLVALRALV
TH_0500|M.thermoresistible__bu      GLPGYGPGDLIDFDFSGDTVEVTFSAGIDHPLRLTSPEATGILVALRALL
MSMEG_3888|M.smegmatis_MC2_155      GLPGYSPGDLIDFDFVGDTIEVTFSAGVDHPLRLTSTEATGILVALRALV
MAB_2186|M.abscessus_ATCC_1997      GLPGYGPGDLIDLSFSEESIEVTFSAGIDRPLRLTSPEATALLVALRALL
                                    ***** ******:.*  :::*******:*:**:***.** .:*****:* 

Mb2122c|M.bovis_AF2122/97           DIPGVVDPQAARSAIAKIAAAAG--------AVAAVAEQAPTESPAAAAV
Rv2095c|M.tuberculosis_H37Rv        DIPGVVDPQAARSAIAKIAAAAG--------AVAAVAEQAPTESPAAAAV
MMAR_3081|M.marinum_M               DIPGVVDPQAARSAIAKIAAAAGAAGHSS--TLSAVDEPAPLESPAAAAV
MUL_2327|M.ulcerans_Agy99           DIPGVVDPQAARSAIAKIAAAAGAAEHSS--TLSAVDEPAPLESPAAAAV
MAV_2408|M.avium_104                DIPGVVDPEAARSAIAKIEGAAGAVGHDTTQAATAVDEPAPAESRAAAAV
MLBr_01330|M.leprae_Br4923          NIPGVVDPEAVRSAIAKIEAAAVVMGNEATGSVASVDTRPFSESHAVAAV
Mflv_3092|M.gilvum_PYR-GCK          DVPGMVDPEAARSAIAKIESAAGTVG--HGVEGAAVEEPAPLESEAAAAV
Mvan_3443|M.vanbaalenii_PYR-1       DVPGMVDPEAARSAIAKIESAAGKVG--HGVEGAAVEEPAPVESAAAAAV
TH_0500|M.thermoresistible__bu      DVPGMVDPAAARSAIAKIEQAAGTVQ--HSAE-TAVDERAPAESAAAAAV
MSMEG_3888|M.smegmatis_MC2_155      DVPGMVDPEAARSAIAKIESAVGSQR--AVVE--GITEDTSAEPGAAATV
MAB_2186|M.abscessus_ATCC_1997      DMPGTVDPEAARSAIAKIEEAVGALP----TDAAPAPLSARTESEAVTAV
                                    ::** *** *.*******  *.                 .  *. *.::*

Mb2122c|M.bovis_AF2122/97           RAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHSYLEAWSREAEG
Rv2095c|M.tuberculosis_H37Rv        RAAVRNSRALTIDYYAASHDTLTTRIVDPIRVLLIGGHSYLEAWSREAEG
MMAR_3081|M.marinum_M               RSAVLDKRALTIDYYSASHDTLTTRTVDPIRVLLIGGHSYLEAWSRESEG
MUL_2327|M.ulcerans_Agy99           RSAVLDKRALTIDYYSASHDTLTTRTVDPIRVLLIGGHSYLEAWSRESEG
MAV_2408|M.avium_104                RAAVQSRHALAIDYYSASRDTLTSRVVDPIRVLLIGGHSYLEAWSREAEG
MLBr_01330|M.leprae_Br4923          RAAVRDKQALVIDYYSASHDTLTSRIVDPIRVLLVGDHSYLEAWSREAEG
Mflv_3092|M.gilvum_PYR-GCK          RTAVRDDRALAIEYYSASHDMLSSRVVDPIRVVLVADHSYLEAWCRTAEA
Mvan_3443|M.vanbaalenii_PYR-1       RKAVRDDRALAIEYYAASHDTMSSRVVDPIRVVLVADHSYLEAWCRSAEA
TH_0500|M.thermoresistible__bu      RAATRDKRALALEYYSASHDQLSSRIVDPIRVVLVADHSYLEAWCRSAEG
MSMEG_3888|M.smegmatis_MC2_155      RTAVRENRALTLEYYSASRDSLATRTVDPIRVVLVGDNSYLEAWCRSAEA
MAB_2186|M.abscessus_ATCC_1997      RSAVRNRQALRIEYYSASRDTLSERIVDPIRIAVVGDHSYLEAWCRGSEG
                                    * *. . :** ::**:**:* :: * *****: ::..:******.* :*.

Mb2122c|M.bovis_AF2122/97           VRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFD---GDLSLPSATLR
Rv2095c|M.tuberculosis_H37Rv        VRLFRFDRIVDAAELGEPAVPPESARQAPPDTSLFD---GDLSLPSATLR
MMAR_3081|M.marinum_M               VRLFRFDRIVDAVELGEPAMPPEPAVQAPPDTSLFD---GDPALPSATLR
MUL_2327|M.ulcerans_Agy99           VRLFRFDRIVDAVELGEPAMPPEPAVQAPPDTSLFD---GDPALPSATLR
MAV_2408|M.avium_104                VRLFRFDRIVEASELDEPAAPPEPVLHAPPDTSLFD---GDPSLPSATLR
MLBr_01330|M.leprae_Br4923          VRLFRFDRIVVARELDEPAAAPETVRKALPDTSFFD---DDPLLPSATLW
Mflv_3092|M.gilvum_PYR-GCK          VRLFRFDRIVDARVLDEPAVPPPPAVQSGPDTSLFDPDTADPSLPTATLL
Mvan_3443|M.vanbaalenii_PYR-1       VRLFRFDRIVDARVLDEPSVPPPPAVQAGPDTSLFDPDTADPSLPVATLL
TH_0500|M.thermoresistible__bu      VRLFRFDRIVDAQVLDEPAAPPEPAVQAEPDTSLFEPDPDDPSFQSATLL
MSMEG_3888|M.smegmatis_MC2_155      VRLFRFDRIVDAQLLDDPAAPPPPAVAAGPDTSLFD---ADPSLPSATLL
MAB_2186|M.abscessus_ATCC_1997      VRLFRFDRIEQAEVLDQRAAPPAPAVQTATDTGLFE---ADPSLPAATVI
                                    *********  *  *.: : .* ..  : .**.:*:    *  :  **: 

Mb2122c|M.bovis_AF2122/97           VAPSASWMLEYYPIR-ELRQLPDGSCEVVMTYASEDWMTRLLLGFGSDVR
Rv2095c|M.tuberculosis_H37Rv        VAPSASWMLEYYPIR-ELRQLPDGSCEVAMTYASEDWMTRLLLGFGSDVR
MMAR_3081|M.marinum_M               VAPSASWMFEYYPIR-ELRQLADGSCEVAMTYASEDWMTRLMLGFGSTVQ
MUL_2327|M.ulcerans_Agy99           VAPSASWMFEYYPIR-ELRQLADGSCEVAMTYASEDWMTRLMLGFGSTVQ
MAV_2408|M.avium_104                VAPHASWMFEYYPMR-DVRELPDGSCEAVMTYASEDWMTRLVLGLGSGVQ
MLBr_01330|M.leprae_Br4923          VARSVSWIFEYYPMR-QAHELPDGSFQAVMTYASDAWMTRLVLGFGSAVQ
Mflv_3092|M.gilvum_PYR-GCK          IDRSAAWMFDYYPLR-VRTEFPDGSCEATMTYASDQWMTRFVLGFGAAVR
Mvan_3443|M.vanbaalenii_PYR-1       IERSAAWMFDYYPLR-VLREFDDGSCEATMTYASDQWMARFVLGFGSAVR
TH_0500|M.thermoresistible__bu      IDRSAGWIFDYYPLR-VLREHDDGSCEAAMTYASDDWMSRLVLGFGSAVR
MSMEG_3888|M.smegmatis_MC2_155      IGAAAAWMFDYYPLR-DITERPDGSCEATMTYASEDWMARFILGFGAEVQ
MAB_2186|M.abscessus_ATCC_1997      VGPSASWVFDYFPMRPTGTQHPDGSLEAAMTYASEDWMARLILGFGSAIR
                                    :   ..*:::*:*:*    :  *** :..*****: **:*::**:*: ::

Mb2122c|M.bovis_AF2122/97           VLAPESLAQRVRDAATAALDAYQAAAPP------
Rv2095c|M.tuberculosis_H37Rv        VLAPESLAQRVRDAATAALDAYQAAAPP------
MMAR_3081|M.marinum_M               VLEPESLAQRVRAAAATALNAYQAAELA------
MUL_2327|M.ulcerans_Agy99           VLEPESLAQRVRAAAATALNAYQAAELA------
MAV_2408|M.avium_104                VLAPHSLAQRVREAATAALAAYEALS--------
MLBr_01330|M.leprae_Br4923          VQAPEALAYRVRNAAVAALESYQVTAQA------
Mflv_3092|M.gilvum_PYR-GCK          VLEPPDLADRVRQTAAAALQAYRVG---IDAPGE
Mvan_3443|M.vanbaalenii_PYR-1       VLEPVDLADRVRRSAAAALEAYRVGGVGIDPADG
TH_0500|M.thermoresistible__bu      VLAPESLARRVAESARAALAVYDLS---AEHAGR
MSMEG_3888|M.smegmatis_MC2_155      VLAPESLATRVRQAAEAALQAYARCV--------
MAB_2186|M.abscessus_ATCC_1997      VLAPESLARRVRADATAALAAYQAS---------
                                    *  *  ** **   * :**  *