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M. thermoresistible (build 8) TH_0496 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 1065467 - 1066597
length: 377

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0496-100% (377)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1822-9e-9046.60% (382) dioxygenase
M. thermoresistible (build 8)TH_4620-4e-8847.00% (383) PUTATIVE 2-nitropropane dioxygenase, NPD

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1927c-0.087.20% (375) hypothetical protein Mb1927c
M. gilvum PYR-GCKMflv_3286-0.084.31% (376) 2-nitropropane dioxygenase, NPD
M. tuberculosis H37RvRv1894c-0.087.20% (375) hypothetical protein Rv1894c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0354c-0.086.67% (375) 2-nitropropane dioxygenase family oxidoreductase
M. marinum MMMAR_2787-0.085.03% (374) hypothetical protein MMAR_2787
M. avium 104MAV_2807-0.086.40% (375) oxidoreductase, 2-nitropropane dioxygenase family protein
M. smegmatis MC2 155MSMEG_3519-0.088.53% (375) oxidoreductase, 2-nitropropane dioxygenase family protein
M. ulcerans Agy99MUL_1143-0.085.56% (374) hypothetical protein MUL_1143
M. vanbaalenii PYR-1Mvan_3005-0.087.73% (375) 2-nitropropane dioxygenase, NPD

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_3519|M.smegmatis_MC2_155      MHTALCDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGYTPEQLEIE
Mvan_3005|M.vanbaalenii_PYR-1       MHTPLCDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
Mflv_3286|M.gilvum_PYR-GCK          MHTPLCDQLGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFSPEQLEIE
Mb1927c|M.bovis_AF2122/97           MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
Rv1894c|M.tuberculosis_H37Rv        MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
MMAR_2787|M.marinum_M               MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
MUL_1143|M.ulcerans_Agy99           MHTAICDELGIEFPIFAFTHCRDVVLAVSKAGGFGVLGAVGFTPEQLEIE
MAV_2807|M.avium_104                MHTAICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
TH_0496|M.thermoresistible__bu      MHTAICDQLGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEVE
MAB_0354c|M.abscessus_ATCC_199      MHTPICDELGIEFPIFAFTHCRDVVVAVSKAGGFGVLGAVGFTPEQLEIE
                                    ***.:**:*****************:***************::*****:*

MSMEG_3519|M.smegmatis_MC2_155      LNWIDEHIGDHPYGVDIVIPNKYEGMDAN-MSAEELKATLNSLVPQEHLD
Mvan_3005|M.vanbaalenii_PYR-1       LNWIDENIGDHPYGVDIVIPNKYEGMDSN-MSADELKSTLNALVPQEHLD
Mflv_3286|M.gilvum_PYR-GCK          LNWIDENIGDHPYGVDIVIPNKYEGMDAADMDPEVLKKTLNDLVPEEHID
Mb1927c|M.bovis_AF2122/97           LNWIDEHIGDHPYGVDIVIPNKYEGMDSQ-LSADELAKTLRSMVPQEHLD
Rv1894c|M.tuberculosis_H37Rv        LNWIDEHIGDHPYGVDIVIPNKYEGMDSQ-LSADELAKTLRSMVPQEHLD
MMAR_2787|M.marinum_M               LTWIDEHIGDHPYGVDIVIPNKYEGMDSH-LSAEELANTLRSMVPQQHLD
MUL_1143|M.ulcerans_Agy99           LNWIDEHIGDHPYGVDIVIPNKYEGMDSH-LSAEELANTLRSMVPQQHLD
MAV_2807|M.avium_104                LKWIDENIGDHPYGVDIVIPNKYEGMDSH-LSAEELAETLRKMVPQEHLD
TH_0496|M.thermoresistible__bu      LNWIDEHIGDHPYGVDIVIPNKYEGMDAN-LTADELAEQLRAMVPQEHLD
MAB_0354c|M.abscessus_ATCC_199      LNWIDEHIGDHPYGVDIVIPNKYEGMDAN-MSAEELTKMLQSMVPQEHLD
                                    *.****:********************:  : .: *   *. :**::*:*

MSMEG_3519|M.smegmatis_MC2_155      FAKKILADHGVPTDELEDNALQLLGWTEATATPQVEIALKHPKMTLIANA
Mvan_3005|M.vanbaalenii_PYR-1       FAKKILADHGVPTDDSDDNALQLLGWTEATATPQVEVALRHPKMTLIANA
Mflv_3286|M.gilvum_PYR-GCK          FAKKILSDHGVPVDHSDDDALQLLGWTEATATPQVEVALRHPKVTMIANA
Mb1927c|M.bovis_AF2122/97           FARKILADHGVPVEDADEDSLQLLGWTEATATPQVDAALKHPKMTMVANA
Rv1894c|M.tuberculosis_H37Rv        FARKILADHGVPVEDADEDSLQLLGWTEATATPQVDAALKHPKMTMVANA
MMAR_2787|M.marinum_M               FARKILADHGVPIEDADEDSLQLLGWTEATATPQVEVALEHSKVTMIANA
MUL_1143|M.ulcerans_Agy99           FARKILADHGVPIEDADEDSLQLLGWTEATATPQVEVALKHSKVTMIANA
MAV_2807|M.avium_104                FGKKILADHGVPIEDSDSDSLQLLGWTEATATPQVEVALKHPKVKMIANA
TH_0496|M.thermoresistible__bu      FARKLLADNGVPVDELNDNALQLLGWTEATATPQVEIALRHPKMTLIANA
MAB_0354c|M.abscessus_ATCC_199      FGRKLLADHGVPVEEGNDNALQLLGWTEATATPQVEIALRHPKMTLIANA
                                    *.:*:*:*:*** :. :.::***************: **.*.*:.::***

MSMEG_3519|M.smegmatis_MC2_155      LGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
Mvan_3005|M.vanbaalenii_PYR-1       LGTPPKDMIEHIHAEGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
Mflv_3286|M.gilvum_PYR-GCK          LGTPPADMIKHIHDEGRVVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
Mb1927c|M.bovis_AF2122/97           LGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
Rv1894c|M.tuberculosis_H37Rv        LGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
MMAR_2787|M.marinum_M               LGTPPAEMIAHIHEQGRKVAALCGSPSQARKHANAGVDIIIAQGGEAGGH
MUL_1143|M.ulcerans_Agy99           LGTPPAEMIAHIHERGRKVAALCGSPSQARKHANAGVDIIIAQGGEAGGH
MAV_2807|M.avium_104                LGTPPADMIKHIHDAGLKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
TH_0496|M.thermoresistible__bu      LGTPPADMIKHIHDSGRKVAALCGSPSQARKHADAGVDIIIAQGGEAGGH
MAB_0354c|M.abscessus_ATCC_199      LGTPPADMIKHIHDAGRKVAALCGSPKQARKHADAGVDIVIAQGGEGGGH
                                    ***** :** ***  *  ********.******:*****:******.***

MSMEG_3519|M.smegmatis_MC2_155      SGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGAQGAWTGSQ
Mvan_3005|M.vanbaalenii_PYR-1       SGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGAQGAWTGSQ
Mflv_3286|M.gilvum_PYR-GCK          CGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGAQGAWTGSQ
Mb1927c|M.bovis_AF2122/97           CGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGTQGAWTGSQ
Rv1894c|M.tuberculosis_H37Rv        CGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGTQGAWTGSQ
MMAR_2787|M.marinum_M               CGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALVLGCQGAWTGSQ
MUL_1143|M.ulcerans_Agy99           CGEVGSIVLWPQVVKEVAPVPVLAAGGIGSGQQIAAALALGCQGAWTGSQ
MAV_2807|M.avium_104                CGEVGSIVLWPQVVKEVAPLPVLAAGGIGSGQQIAAALALGAQGAWTGSQ
TH_0496|M.thermoresistible__bu      AGEIGSIVLWPQVVKEVAPIPVLAAGGIGSGQQIAAALALGAQGAWTGSQ
MAB_0354c|M.abscessus_ATCC_199      CGEVGSIVLWPQVVKEIAPVPVLAAGGIGSGYQIAAALAMGAQGAWSGSQ
                                    .**:************:**:*********** ******.:* ****:***

MSMEG_3519|M.smegmatis_MC2_155      WVMVEESENTPVQHAAYVKATSRDTVRSRSFTGKPARMLRNDWTEAWENP
Mvan_3005|M.vanbaalenii_PYR-1       WVMVEESENTPVQHAAYAKATSRDTVRSRSFTGKPARMLRNDWTEAWENP
Mflv_3286|M.gilvum_PYR-GCK          WVIVEESENTPVQHEAYIKAGSRDTVRSRSFTGKPARMLRNDWTEAWEDE
Mb1927c|M.bovis_AF2122/97           WLMVEEAANTAVQQAAYVKATSRDTVRSRSFTGKPARMLRNDWTEAWEQP
Rv1894c|M.tuberculosis_H37Rv        WLMVEEAANTAVQQAAYVKATSRDTVRSRSFTGKPARMLRNDWTEAWEQP
MMAR_2787|M.marinum_M               WLMVEEASNTPVQQAAYAKASSRDTVRSRSFTGKPARMLRNDWTEAWEQA
MUL_1143|M.ulcerans_Agy99           WLMVEEASNTPVQQAAYAKASSRDTVRSRSFTGKPARMLRNDWTEAWEQA
MAV_2807|M.avium_104                WLMVEESSNTPVQQAAYAKAGSRDTVRSRSFTGKPARMLRNDWTEAWEAP
TH_0496|M.thermoresistible__bu      WLMVEEAENTPVQQAAYAKATSKDTVRSRSFTGKPARMLRNKWTEAWEHP
MAB_0354c|M.abscessus_ATCC_199      WLMVEEAENTAVQQETYVKATSRDTVRSRSFTGKPCRMLKNDWTEAWQTE
                                    *::***: **.**: :* ** *:************.***:*.*****:  

MSMEG_3519|M.smegmatis_MC2_155      ENPKPLGMPLQYMVSGMAVAATHKYPNESVDVAFNPIGQVVGQFTKVEKT
Mvan_3005|M.vanbaalenii_PYR-1       ENPKPLGMPLQYMVSGMAVAATHKYPNETVDVAFNPIGQVVGQFTKVEKT
Mflv_3286|M.gilvum_PYR-GCK          NNPKPLGMPLQYMVSGMAVAATHKYPNESVDVAFNPIGQVVGQFTKVEKT
Mb1927c|M.bovis_AF2122/97           ESPKPLGMPLQYMVSGMAVKATHKYPNETVDVAFNPVGQVVGQFTKVEKT
Rv1894c|M.tuberculosis_H37Rv        ESPKPLGMPLQYMVSGMAVKATHKYPNETVDVAFNPVGQVVGQFTKVEKT
MMAR_2787|M.marinum_M               DNPKPLGMPLQYMVSGMAVRATNKHPNETVDVAFNPVGQVVGQFTKVEKA
MUL_1143|M.ulcerans_Agy99           DNPKPLGMPLQYMVSGMAVRATNKYPNETVDVAFNPVGQVVGQFTKVEKA
MAV_2807|M.avium_104                GNPKPLGMPLQYMVSGMAVRATNKYPNESVDVAFNPVGQVVGQFTKVEKT
TH_0496|M.thermoresistible__bu      DNPKPLPMPLQYMVSGMAVAATSRYPDQSVDVAFNPVGQVVGQFSKVEKC
MAB_0354c|M.abscessus_ATCC_199      GNPEPLGMPLQYMVSGMAVAATHKFPDQTIDVAFNPIGQVVGQFTKVEKS
                                     .*:** ************ ** :.*::::******:*******:**** 

MSMEG_3519|M.smegmatis_MC2_155      SAVIERWVQEYLEATSTLNALNEAASV-
Mvan_3005|M.vanbaalenii_PYR-1       ATVIERWVQEYLEATNTLNELNEAASV-
Mflv_3286|M.gilvum_PYR-GCK          ATVIERWVQEYLEATGRLNELNEAASV-
Mb1927c|M.bovis_AF2122/97           ATVIERWVQEYLEATARLDALNAAASV-
Rv1894c|M.tuberculosis_H37Rv        ATVIERWVQEYLEATARLDALNAAASV-
MMAR_2787|M.marinum_M               ATVIERWVQEYLEATNRLDELNAAAV--
MUL_1143|M.ulcerans_Agy99           ATVIERWVQEYLEATNRLDELNAAAV--
MAV_2807|M.avium_104                ATVIERWVQEYLEATNRLDELNEAASV-
TH_0496|M.thermoresistible__bu      ATVIERWVQEYLEATATLNELNEAAAR-
MAB_0354c|M.abscessus_ATCC_199      AAVIERWVQEYLEATNTLNELNEAAASV
                                    ::*************  *: ** **