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M. thermoresistible (build 8) TH_0369 ()

annotation: PROBABLE HYDRATASE
coordinates: 817319 - 818104
length: 262

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0369-100% (262)PROBABLE HYDRATASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3566c-1e-11378.16% (261) hydratase
M. gilvum PYR-GCKMflv_1520-1e-12583.91% (261) 4-oxalocrotonate decarboxylase
M. tuberculosis H37RvRv3536c-1e-11378.16% (261) hydratase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0624-1e-11072.41% (261) hydratase/decarboxylase
M. marinum MMMAR_5023-1e-11677.78% (261) 2-keto-4-pentenoate hydratase
M. avium 104MAV_0625-1e-11880.84% (261) 2-keto-4-pentenoate hydratase
M. smegmatis MC2 155MSMEG_5940-1e-12887.36% (261) 2-keto-4-pentenoate hydratase
M. ulcerans Agy99MUL_4097-1e-11777.78% (261) 2-keto-4-pentenoate hydratase
M. vanbaalenii PYR-1Mvan_5236-1e-12987.36% (261) 4-oxalocrotonate decarboxylase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3566c|M.bovis_AF2122/97           --------------------------------------------------
Rv3536c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_5023|M.marinum_M               --------------------------------------------------
MUL_4097|M.ulcerans_Agy99           MRRQGQPPCRRRRFRPRRRRSPVMSCRTRYRIARVGRYWPGHHDARKTRG
MAV_0625|M.avium_104                --------------------------------------------------
TH_0369|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5940|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1520|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5236|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0624|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb3566c|M.bovis_AF2122/97           ---MLRDATRDELAADLAQAERSRDPIGQLTAAHPEIDVVDAYEIQLINI
Rv3536c|M.tuberculosis_H37Rv        ---MLRDATRDELAADLAQAERSRDPIGQLTAAHPEIDVVDAYEIQLINI
MMAR_5023|M.marinum_M               ---MLADSTRDKIAADLAQAERSRQPITPLTPSYPDIDVVDAYQIQLINI
MUL_4097|M.ulcerans_Agy99           LREMLADSTRDKIAADLAQAERSRQPITPLTPSYPDIDVVDAYQIQLINI
MAV_0625|M.avium_104                ---MLSVATRDELAAELAQAERSGEPIPPLTAAYPEIDVVDAYEIQLINI
TH_0369|M.thermoresistible__bu      ---MLSAQVREQLAAELAQAERSRVPITPLTDRHPGIDVVDAYEIQLINI
MSMEG_5940|M.smegmatis_MC2_155      ---MLSDEVRARLAADLAQAERSRQPITPLTDGNPDIDVVDAYEIQLINI
Mflv_1520|M.gilvum_PYR-GCK          ---MLPAEVREKLAADLAEAEQSRKPISPLTDAHPDIDVVDAYEIQLINI
Mvan_5236|M.vanbaalenii_PYR-1       ---MLSVEVREKLAADLAEAERSRVPISPLTDGQPGIDVVDAYEIQLINI
MAB_0624|M.abscessus_ATCC_1997      ---MLSSEVRDSIAADLAEAERTRVAIAPPTDTHPDFDVVDAYEIQLMNI
                                       **   .*  :**:**:**::  .*   *   * :******:***:**

Mb3566c|M.bovis_AF2122/97           RQRVAEGARVVGHKVGLSSPIMQQMMGVDEPDYGHLLDDMQVFEDTPVQA
Rv3536c|M.tuberculosis_H37Rv        RQRVAEGARVVGHKVGLSSPIMQQMMGVDEPDYGHLLDDMQVFEDTPVQA
MMAR_5023|M.marinum_M               RRRVAEGGRVVGHKVGLSSPVMQQMMGVDEPDYGHLLDNMRVFEDAPVRT
MUL_4097|M.ulcerans_Agy99           RRRVAEGGRVVGHKVGLSSPVMQQMMGVDEPDYGHLLDNMRVFEDAPVRT
MAV_0625|M.avium_104                RQRVAEGARVLGHKVGLSSLAIQQMMGVDEPDYGHLLDDMQLFEDTPVKT
TH_0369|M.thermoresistible__bu      RQRVAEGARVVGHKVGLSSEAMQKMMGVDEPDYGHLLDDMQVFEDKPVKS
MSMEG_5940|M.smegmatis_MC2_155      RQRIAEGAKVVGHKVGLSSKAMQEMMGVDEPDYGHLLDDMQVYEDQPVKS
Mflv_1520|M.gilvum_PYR-GCK          RRRVADGARIIGHKVGLSSEAMQKMMGVDEPDYGHLLEEMQVFEDVPVGS
Mvan_5236|M.vanbaalenii_PYR-1       RQRVAEGARVIGHKVGLSSEAMQKMMNVDEPDYGHLLDEMQVFENVAVKS
MAB_0624|M.abscessus_ATCC_1997      RSRLADGAKVVGHKVGLSSEAMQKMMGVHEPDYGHLLADMELFEDVAASA
                                    * *:*:*.:::********  :*:**.*.******** :*.::*: .. :

Mb3566c|M.bovis_AF2122/97           SRYLSPRVEVEVGFILAADLPGAGCTEDDVLAATEALVPAIELIDTRIKD
Rv3536c|M.tuberculosis_H37Rv        SRYLSPRVEVEVGFILAADLPGAGCTEDDVLAATEALVPAIELIDTRIKD
MMAR_5023|M.marinum_M               ANYLYPRVEVEVGFILAADLPGADCTEDDVLAATEALVPSIELIDTRIKD
MUL_4097|M.ulcerans_Agy99           ANYLYPRVEVEVGFILAADLPGADCTEDDVLAATEALVPSIELIDTRIKD
MAV_0625|M.avium_104                NRYLYPRVEVEVGFILNADLPGAGCTEDDVMAATEAFVPAIELIDTRITD
TH_0369|M.thermoresistible__bu      ANYLYPRVEVEVGFILAADLPGADCTEEDVLAATEAFAPAIELIDTRITD
MSMEG_5940|M.smegmatis_MC2_155      ANYLYPRVEVEVGFILADDLPGAGCTEEDVLAATAAFAPAIELIDTRITN
Mflv_1520|M.gilvum_PYR-GCK          GRYLYPRVEVEVGFILSDDLPGAGCTEDDVLAATAAFAPAIELIDTRITN
Mvan_5236|M.vanbaalenii_PYR-1       ANYLYPRVEVEVGFILSDDLPGAGCTEDDVLAATAAFAPAIELIDTRITN
MAB_0624|M.abscessus_ATCC_1997      SKFLFPRVEVEVGFILAADLPGEDCTEDDVLAATAAYVPSIEVVDSRITN
                                     .:* ***********  **** .***:**:*** * .*:**::*:**.:

Mb3566c|M.bovis_AF2122/97           WQIKICDTIADNASAAGFVLGAARVPPADLDVRAIDAKLTRNGEVVAEGR
Rv3536c|M.tuberculosis_H37Rv        WQIKICDTIADNASAAGFVLGAARVPPADLDVRAIDAKLTRNGEVVAEGR
MMAR_5023|M.marinum_M               WQIKICDTIADNASAAGFVLGAARVSPAEVDVKAIDAVLTRNGELAAEGR
MUL_4097|M.ulcerans_Agy99           WQIKICDTIADNASAAGFVLGAARVSPAEVDVKAIDAVLTRNGELAAEGR
MAV_0625|M.avium_104                WKIELCDTIADNASSAGFVLGAARVSPQDIDIKGIDAVLRRNGEVVAEGR
TH_0369|M.thermoresistible__bu      WKIKLCDTIADNASSAGWVLGEARVSPEEIDITTIEATLTNNGEVVAQGR
MSMEG_5940|M.smegmatis_MC2_155      WQIKLCDTIADNASSAGWVLGEARVSPKDIDIRNIDAVLKNNGEVVAEGR
Mflv_1520|M.gilvum_PYR-GCK          WQIKLCDTIADNASSAGWVLGEARVSPKDVDIRAIDAVLTNNGEVVAEGR
Mvan_5236|M.vanbaalenii_PYR-1       WQIKLCDTIADNASSAGWVLGEARVSPKDVDIKNIDAVLTNNGEVVAEGR
MAB_0624|M.abscessus_ATCC_1997      WQIKICDTIADNASSAGFVVGKQRVSPKDIDIKSIDAVLTCNGEKLAEGR
                                    *:*::*********:**:*:*  **.* ::*:  *:* *  ***  *:**

Mb3566c|M.bovis_AF2122/97           SDAVLGNPATAVAWLAGKVESFGVRLRKGDIVLPGSCTFAVEARAGDEFV
Rv3536c|M.tuberculosis_H37Rv        SDAVLGNPATAVAWLAGKVESFGVRLRKGDIVLPGSCTFAVEARAGDEFV
MMAR_5023|M.marinum_M               SDAVLGNPATAVAWLARKVEGFGVRLRKGDIVLPGSCTFAVDANAGDEFV
MUL_4097|M.ulcerans_Agy99           SDAVLGNPATAVAWLARKVEGFGVRLRKGDIVLPGSCTFAVDANAGDEFV
MAV_0625|M.avium_104                TDAVLGNPVTAVAWLARKVDGFGVRLRKGDVVLPGSCTKAIDAHPGDEFV
TH_0369|M.thermoresistible__bu      SDAVLGNPVTAVAWLARKVDSFGVRLKAGDIVLPGSCTRAIDAPAGSHFV
MSMEG_5940|M.smegmatis_MC2_155      SDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDAPAGSDFV
Mflv_1520|M.gilvum_PYR-GCK          SDAVLGNPVTAVAWLARKVEAFGVRLKAGDIVLPGSCTRAIDAPPGSRFV
Mvan_5236|M.vanbaalenii_PYR-1       SDAVLGNPVTAVAWLARKVESFGVRLKAGDIVLPGSCTRAIDAPAGSHFV
MAB_0624|M.abscessus_ATCC_1997      SDAVLGNPVTSVAWLARKVASFGVRLRAGDVVLPGSCTRAFDAHPGDEFL
                                    :*******.*:***** ** .*****: **:******* *.:* .*. *:

Mb3566c|M.bovis_AF2122/97           ADFTGLGLVRLSFE
Rv3536c|M.tuberculosis_H37Rv        ADFTGLGLVRLSFE
MMAR_5023|M.marinum_M               ADFTGLGSVRLSFQ
MUL_4097|M.ulcerans_Agy99           ADFTGLGSVRLSFQ
MAV_0625|M.avium_104                ADFAGLGSVRLSFE
TH_0369|M.thermoresistible__bu      ADFSGLGSVQLSFE
MSMEG_5940|M.smegmatis_MC2_155      ADFAGLGSVHLRFE
Mflv_1520|M.gilvum_PYR-GCK          ADFTGLGSVRLDFE
Mvan_5236|M.vanbaalenii_PYR-1       ADFTGLGSVRLDFE
MAB_0624|M.abscessus_ATCC_1997      AEFAGLGSVRLAFE
                                    *:*:*** *:* *: