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M. thermoresistible (build 8) TH_0274 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 613918 - 614967
length: 350

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0274-100% (350)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2904c-1e-16782.81% (349) hypothetical protein Mb2904c
M. gilvum PYR-GCKMflv_4121-1e-17285.43% (350) radical SAM protein
M. tuberculosis H37RvRv2879c-4e-8984.49% (187) hypothetical protein Rv2879c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3175c-1e-16281.02% (353) hypothetical protein MAB_3175c
M. marinum MMMAR_1830-1e-16781.95% (349) hypothetical protein MMAR_1830
M. avium 104-----
M. smegmatis MC2 155MSMEG_2545-1e-17583.84% (359) radical SAM enzyme, Cfr family protein
M. ulcerans Agy99MUL_2078-1e-16881.95% (349) hypothetical protein MUL_2078
M. vanbaalenii PYR-1Mvan_2223-1e-17586.57% (350) radical SAM protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2904c|M.bovis_AF2122/97           MVP-----ELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLA
Rv2879c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1830|M.marinum_M               MAQ-----ELMFEEPRRGKPPRHLADFDAEGRASAVAALGLPPFRAKQLA
MUL_2078|M.ulcerans_Agy99           MAQ-----ELMFEEPRRGKPPRHLADFDAEGRASAVAALGLPPFRAKQLA
MSMEG_2545|M.smegmatis_MC2_155      MKQ-----QLVFEAPRRAMPPQHLADLDETARAAAVTELGLPAFRAKQLA
Mflv_4121|M.gilvum_PYR-GCK          MPDP---LPLVFDAPRRALPPRHFADLADTERAAAVADLGLPAFRGKQLA
Mvan_2223|M.vanbaalenii_PYR-1       MPNP---LPLVFDAPRRAMPPRHFADLDESGRAAAVAELGLPAFRAKQLA
TH_0274|M.thermoresistible__bu      ------------------MPPRHLADLDEAQRATAVADLGLPAFRAKQLA
MAB_3175c|M.abscessus_ATCC_199      MPADNKPLPLVFDAPRRAMPPRHLADMSLEQSRDVVTELGLPAFRAKQIA
                                                                                      

Mb2904c|M.bovis_AF2122/97           HQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKT
Rv2879c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1830|M.marinum_M               HQYYGRLIADPRQMTDLPAAVREQIAETMFPNLLTAAREVTCDAGQTRKT
MUL_2078|M.ulcerans_Agy99           HQYYGRLIADPRQMTDLPAAVRDQIAETMFPNLLTAAREVTCDAGQTRKT
MSMEG_2545|M.smegmatis_MC2_155      NQYYGRLIADPQQMTDLPAAVRDQVAEKLFPTLINPVREIQCDAGETRKT
Mflv_4121|M.gilvum_PYR-GCK          NQYFGRLISDPSQMTDLPAGVRDQVGAALFPELLEAAREIECDRGETRKV
Mvan_2223|M.vanbaalenii_PYR-1       NQYYGRLIADPTQMTDLPAAVRERVADALFPTLFGAAREIECDSGETRKV
TH_0274|M.thermoresistible__bu      NQYYGRLVADPQQMTDLPAAVRDSVAEALFPRLLDPVREIECDAGETRKT
MAB_3175c|M.abscessus_ATCC_199      NQYYGRLVGDPATMTDLPAGARGGVAEALFPRLLEPLRQIACDAGDTRKT
                                                                                      

Mb2904c|M.bovis_AF2122/97           LWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLS
Rv2879c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1830|M.marinum_M               LWRATDGVTLESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLTRNLS
MUL_2078|M.ulcerans_Agy99           LWRATDGVTVESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLTRNLS
MSMEG_2545|M.smegmatis_MC2_155      LWRAIDGSTFESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLQRNLT
Mflv_4121|M.gilvum_PYR-GCK          LWRAVDKTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGGLKRNLS
Mvan_2223|M.vanbaalenii_PYR-1       LWRAVDGTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGGLKRNLS
TH_0274|M.thermoresistible__bu      LWRAVDGTTFESVLMRYPDRHTLCISSQAGCGMACPFCATGQGGLNRNLS
MAB_3175c|M.abscessus_ATCC_199      LWRLHDGSTVESVLMRYPDRNTLCISSQAGCGMACPFCATGQGGLTRNLS
                                                                                      

Mb2904c|M.bovis_AF2122/97           TAEILEQVRAGAAALR-DDFG--------DRLSNVVFMGMGEPLANYARV
Rv2879c|M.tuberculosis_H37Rv        ---------------------------------------WGEPLANYARV
MMAR_1830|M.marinum_M               TAEILEQVRAAAAALR-DEFG--------DRLSNVVFMGMGEPLANYARV
MUL_2078|M.ulcerans_Agy99           TAEIVEQVRAAAAALR-DEFG--------DRLSNVVFMGLGEPLANYARV
MSMEG_2545|M.smegmatis_MC2_155      TAEILEQVRAASSTMRAEHFGRTAGTAGGGRLSNIVFMGMGEPLANYNRV
Mflv_4121|M.gilvum_PYR-GCK          TAEILEQVRFASAELR-DREG--------GRLSNIVFMGMGEPLANYNRV
Mvan_2223|M.vanbaalenii_PYR-1       TAEILEQVRAASAELR-DRDG--------GRLSNVVFMGMGEPLANYNRV
TH_0274|M.thermoresistible__bu      TAEILEQVRTAAARLR--SDG--------QRLSNIVFMGMGEPLANYRRV
MAB_3175c|M.abscessus_ATCC_199      AAEILEQVRDAAASLRDGQLP-----GGPGRLSNIVFMGMGEPLANYNRV
                                                                            ******* **

Mb2904c|M.bovis_AF2122/97           LAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLH
Rv2879c|M.tuberculosis_H37Rv        LAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLH
MMAR_1830|M.marinum_M               LAAVRRITEPPPMGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
MUL_2078|M.ulcerans_Agy99           LAAVRRITEPPPTGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
MSMEG_2545|M.smegmatis_MC2_155      LGAVRRIIAAPPNGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
Mflv_4121|M.gilvum_PYR-GCK          VAAVRRITASSPHGFGISARSVTVSTVGLAPAIRKLADEKLNVTLAVSLH
Mvan_2223|M.vanbaalenii_PYR-1       VAAVRRITASSPNGFGISARSVTVSTVGLAPAIRKLADEKLNVTLALSLH
TH_0274|M.thermoresistible__bu      LAAVRRITAAPPHGFGISARSVTVSTVGLAPAIRNLADEQLGVTLAVSLH
MAB_3175c|M.abscessus_ATCC_199      LTVLRKITAPPPEGFGISQRGVTVSTVGLAPAIRRLADEGLGVTLAVSLH
                                    : .:::*   .* ***** *.*************.***  *.****:***

Mb2904c|M.bovis_AF2122/97           APDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQ
Rv2879c|M.tuberculosis_H37Rv        APDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQ
MMAR_1830|M.marinum_M               APDDELRDTLVPVNNRWKISEALEAAHYYAEVTGRRVSVEYALIREVNDQ
MUL_2078|M.ulcerans_Agy99           APDDELRDTLVPVNNRWKISEALEAAHYYAEVTGRRVSVEYALIREVNDQ
MSMEG_2545|M.smegmatis_MC2_155      APDDELRDTLVPVNNRWKVSEVLDAARYYADTTGRRVSIEYALIRDVNDQ
Mflv_4121|M.gilvum_PYR-GCK          TPDDELRDTLVPVNNRWKVDEVLDAARYYADLTGRRVSIEYALIRDVNDQ
Mvan_2223|M.vanbaalenii_PYR-1       TPDDELRDTLVPVNNRWKVDEVLDAARYYADVTGRRVSIEYALIRDVNDQ
TH_0274|M.thermoresistible__bu      APDDELRDTLVPVNTRWKVREVLDAARYFADTTGRRVSIEYALIRGVNDQ
MAB_3175c|M.abscessus_ATCC_199      CPDDELRDTLVPVNTRWAISEVLDAARYYADVTGRRVSIEYALIRDVNDQ
                                     *** *********.** : *.*:**:*:*: ******:****** ****

Mb2904c|M.bovis_AF2122/97           PWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
Rv2879c|M.tuberculosis_H37Rv        PWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MMAR_1830|M.marinum_M               PWRADLLGKRLHRALGPLVHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MUL_2078|M.ulcerans_Agy99           PWRADLLGKRLHGALGPLVHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MSMEG_2545|M.smegmatis_MC2_155      PWRADLLGKKLHGALGPLAHVNVIPLNPTPGSEWDASPKPAEREFVKRVR
Mflv_4121|M.gilvum_PYR-GCK          PWRADLLGRKLHATLGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
Mvan_2223|M.vanbaalenii_PYR-1       PWRADLLGKKLHGELGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
TH_0274|M.thermoresistible__bu      PWRADLLGRKLHGALGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
MAB_3175c|M.abscessus_ATCC_199      PWRADMLGKKLRKALGQMVHVNLIPLNPTPGSQWDASPKPVEREFVRRVR
                                    *****:**::*:  ** :.***:*********:*******.*****:***

Mb2904c|M.bovis_AF2122/97           AKGVSCTVRDTRGREISAACGQLAAVGG
Rv2879c|M.tuberculosis_H37Rv        AKGVSCTVRDTRGREISAACGQLAAVGG
MMAR_1830|M.marinum_M               AQGVSCTVRDTRGREISAACGQLAAEGG
MUL_2078|M.ulcerans_Agy99           AQGVSCTVRDTRGREISAACGQLAAEGG
MSMEG_2545|M.smegmatis_MC2_155      ERGVSCTVRDTRGREIAAACGQLAAEG-
Mflv_4121|M.gilvum_PYR-GCK          AKGVSCTVRDTRGREIAAACGQLAAQG-
Mvan_2223|M.vanbaalenii_PYR-1       AKGVSCTVRDTRGREIAAACGQLAAEG-
TH_0274|M.thermoresistible__bu      ACGVPCTVRDTRGREIAAACGQLAADG-
MAB_3175c|M.abscessus_ATCC_199      EQGVSCTVRDTRGREIAAACGQLAASER
                                      **.***********:********