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PDPLPLVFDAPRRALPPRHFADLADTERAAAVADLGLPAFRGKQLANQYFGRLISDPSQMTDLPAGVRDQ VGAALFPELLEAAREIECDRGETRKVLWRAVDKTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGG LKRNLSTAEILEQVRFASAELRDREGGRLSNIVFMGMGEPLANYNRVVAAVRRITASSPHGFGISARSVT VSTVGLAPAIRKLADEKLNVTLAVSLHTPDDELRDTLVPVNNRWKVDEVLDAARYYADLTGRRVSIEYAL IRDVNDQPWRADLLGRKLHATLGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVRAKGVSCTVRDTRG REIAAACGQLAAQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4121 | - | - | 100% (365) | radical SAM protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2904c | - | 1e-167 | 79.67% (359) | hypothetical protein Mb2904c |
| M. tuberculosis H37Rv | Rv2879c | - | 7e-90 | 84.49% (187) | hypothetical protein Rv2879c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3175c | - | 1e-164 | 78.02% (364) | hypothetical protein MAB_3175c |
| M. marinum M | MMAR_1830 | - | 1e-167 | 79.39% (359) | hypothetical protein MMAR_1830 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2545 | - | 1e-174 | 81.25% (368) | radical SAM enzyme, Cfr family protein |
| M. thermoresistible (build 8) | TH_0274 | - | 1e-172 | 85.43% (350) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2078 | - | 1e-167 | 79.11% (359) | hypothetical protein MUL_2078 |
| M. vanbaalenii PYR-1 | Mvan_2223 | - | 0.0 | 91.51% (365) | radical SAM protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4121|M.gilvum_PYR-GCK MPDP---LPLVFDAPRRALPPRHFADLADTERAAAVADLGLPAFRGKQLA
Mvan_2223|M.vanbaalenii_PYR-1 MPNP---LPLVFDAPRRAMPPRHFADLDESGRAAAVAELGLPAFRAKQLA
Mb2904c|M.bovis_AF2122/97 MVP-----ELMFDEPRPGRPPRHLADLDAAGRASAVAELGLPAFRAKQLA
Rv2879c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1830|M.marinum_M MAQ-----ELMFEEPRRGKPPRHLADFDAEGRASAVAALGLPPFRAKQLA
MUL_2078|M.ulcerans_Agy99 MAQ-----ELMFEEPRRGKPPRHLADFDAEGRASAVAALGLPPFRAKQLA
MSMEG_2545|M.smegmatis_MC2_155 MKQ-----QLVFEAPRRAMPPQHLADLDETARAAAVTELGLPAFRAKQLA
TH_0274|M.thermoresistible__bu ------------------MPPRHLADLDEAQRATAVADLGLPAFRAKQLA
MAB_3175c|M.abscessus_ATCC_199 MPADNKPLPLVFDAPRRAMPPRHLADMSLEQSRDVVTELGLPAFRAKQIA
Mflv_4121|M.gilvum_PYR-GCK NQYFGRLISDPSQMTDLPAGVRDQVGAALFPELLEAAREIECDRGETRKV
Mvan_2223|M.vanbaalenii_PYR-1 NQYYGRLIADPTQMTDLPAAVRERVADALFPTLFGAAREIECDSGETRKV
Mb2904c|M.bovis_AF2122/97 HQYYGRLIADPRQMTDLPAAVRDRIAGAMFPNLLTASADITCDAGQTRKT
Rv2879c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1830|M.marinum_M HQYYGRLIADPRQMTDLPAAVREQIAETMFPNLLTAAREVTCDAGQTRKT
MUL_2078|M.ulcerans_Agy99 HQYYGRLIADPRQMTDLPAAVRDQIAETMFPNLLTAAREVTCDAGQTRKT
MSMEG_2545|M.smegmatis_MC2_155 NQYYGRLIADPQQMTDLPAAVRDQVAEKLFPTLINPVREIQCDAGETRKT
TH_0274|M.thermoresistible__bu NQYYGRLVADPQQMTDLPAAVRDSVAEALFPRLLDPVREIECDAGETRKT
MAB_3175c|M.abscessus_ATCC_199 NQYYGRLVGDPATMTDLPAGARGGVAEALFPRLLEPLRQIACDAGDTRKT
Mflv_4121|M.gilvum_PYR-GCK LWRAVDKTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGGLKRNLS
Mvan_2223|M.vanbaalenii_PYR-1 LWRAVDGTTFESVLMRYPDRNTVCISSQAGCGMACPFCATGQGGLKRNLS
Mb2904c|M.bovis_AF2122/97 LWRAVDGTMFESVLMRYPRRNTVCISSQAGCGMACPFCATGQGGLTRNLS
Rv2879c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1830|M.marinum_M LWRATDGVTLESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLTRNLS
MUL_2078|M.ulcerans_Agy99 LWRATDGVTVESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLTRNLS
MSMEG_2545|M.smegmatis_MC2_155 LWRAIDGSTFESVLMRYPQRNTVCISSQAGCGMACPFCATGQGGLQRNLT
TH_0274|M.thermoresistible__bu LWRAVDGTTFESVLMRYPDRHTLCISSQAGCGMACPFCATGQGGLNRNLS
MAB_3175c|M.abscessus_ATCC_199 LWRLHDGSTVESVLMRYPDRNTLCISSQAGCGMACPFCATGQGGLTRNLS
Mflv_4121|M.gilvum_PYR-GCK TAEILEQVRFASAELR-DREG--------GRLSNIVFMGMGEPLANYNRV
Mvan_2223|M.vanbaalenii_PYR-1 TAEILEQVRAASAELR-DRDG--------GRLSNVVFMGMGEPLANYNRV
Mb2904c|M.bovis_AF2122/97 TAEILEQVRAGAAALR-DDFG--------DRLSNVVFMGMGEPLANYARV
Rv2879c|M.tuberculosis_H37Rv ---------------------------------------WGEPLANYARV
MMAR_1830|M.marinum_M TAEILEQVRAAAAALR-DEFG--------DRLSNVVFMGMGEPLANYARV
MUL_2078|M.ulcerans_Agy99 TAEIVEQVRAAAAALR-DEFG--------DRLSNVVFMGLGEPLANYARV
MSMEG_2545|M.smegmatis_MC2_155 TAEILEQVRAASSTMRAEHFGRTAGTAGGGRLSNIVFMGMGEPLANYNRV
TH_0274|M.thermoresistible__bu TAEILEQVRTAAARLR--SDG--------QRLSNIVFMGMGEPLANYRRV
MAB_3175c|M.abscessus_ATCC_199 AAEILEQVRDAAASLRDGQLP-----GGPGRLSNIVFMGMGEPLANYNRV
******* **
Mflv_4121|M.gilvum_PYR-GCK VAAVRRITASSPHGFGISARSVTVSTVGLAPAIRKLADEKLNVTLAVSLH
Mvan_2223|M.vanbaalenii_PYR-1 VAAVRRITASSPNGFGISARSVTVSTVGLAPAIRKLADEKLNVTLALSLH
Mb2904c|M.bovis_AF2122/97 LAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLH
Rv2879c|M.tuberculosis_H37Rv LAAVQRITARPPSGFGISARAVTVSTVGLAPAIRNLADARLGVTLALSLH
MMAR_1830|M.marinum_M LAAVRRITEPPPMGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
MUL_2078|M.ulcerans_Agy99 LAAVRRITEPPPTGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
MSMEG_2545|M.smegmatis_MC2_155 LGAVRRIIAAPPNGFGISARSVTVSTVGLAPAIRKLADERLGVTLALSLH
TH_0274|M.thermoresistible__bu LAAVRRITAAPPHGFGISARSVTVSTVGLAPAIRNLADEQLGVTLAVSLH
MAB_3175c|M.abscessus_ATCC_199 LTVLRKITAPPPEGFGISQRGVTVSTVGLAPAIRRLADEGLGVTLAVSLH
: .:::* .* ***** *.*************.*** *.****:***
Mflv_4121|M.gilvum_PYR-GCK TPDDELRDTLVPVNNRWKVDEVLDAARYYADLTGRRVSIEYALIRDVNDQ
Mvan_2223|M.vanbaalenii_PYR-1 TPDDELRDTLVPVNNRWKVDEVLDAARYYADVTGRRVSIEYALIRDVNDQ
Mb2904c|M.bovis_AF2122/97 APDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQ
Rv2879c|M.tuberculosis_H37Rv APDDGLRDTLVPVNNRWRISEALDAARYYANVTGRRVSIEYALIRDVNDQ
MMAR_1830|M.marinum_M APDDELRDTLVPVNNRWKISEALEAAHYYAEVTGRRVSVEYALIREVNDQ
MUL_2078|M.ulcerans_Agy99 APDDELRDTLVPVNNRWKISEALEAAHYYAEVTGRRVSVEYALIREVNDQ
MSMEG_2545|M.smegmatis_MC2_155 APDDELRDTLVPVNNRWKVSEVLDAARYYADTTGRRVSIEYALIRDVNDQ
TH_0274|M.thermoresistible__bu APDDELRDTLVPVNTRWKVREVLDAARYFADTTGRRVSIEYALIRGVNDQ
MAB_3175c|M.abscessus_ATCC_199 CPDDELRDTLVPVNTRWAISEVLDAARYYADVTGRRVSIEYALIRDVNDQ
*** *********.** : *.*:**:*:*: ******:****** ****
Mflv_4121|M.gilvum_PYR-GCK PWRADLLGRKLHATLGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
Mvan_2223|M.vanbaalenii_PYR-1 PWRADLLGKKLHGELGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
Mb2904c|M.bovis_AF2122/97 PWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
Rv2879c|M.tuberculosis_H37Rv PWRADLLGKRLHRVLGPLAHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MMAR_1830|M.marinum_M PWRADLLGKRLHRALGPLVHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MUL_2078|M.ulcerans_Agy99 PWRADLLGKRLHGALGPLVHVNLIPLNPTPGSDWDASPKPVEREFVKRVR
MSMEG_2545|M.smegmatis_MC2_155 PWRADLLGKKLHGALGPLAHVNVIPLNPTPGSEWDASPKPAEREFVKRVR
TH_0274|M.thermoresistible__bu PWRADLLGRKLHGALGPLVHVNLIPLNPTPGSEWDASPKPVEREFVRRVR
MAB_3175c|M.abscessus_ATCC_199 PWRADMLGKKLRKALGQMVHVNLIPLNPTPGSQWDASPKPVEREFVRRVR
*****:**::*: ** :.***:*********:*******.*****:***
Mflv_4121|M.gilvum_PYR-GCK AKGVSCTVRDTRGREIAAACGQLAAQG-
Mvan_2223|M.vanbaalenii_PYR-1 AKGVSCTVRDTRGREIAAACGQLAAEG-
Mb2904c|M.bovis_AF2122/97 AKGVSCTVRDTRGREISAACGQLAAVGG
Rv2879c|M.tuberculosis_H37Rv AKGVSCTVRDTRGREISAACGQLAAVGG
MMAR_1830|M.marinum_M AQGVSCTVRDTRGREISAACGQLAAEGG
MUL_2078|M.ulcerans_Agy99 AQGVSCTVRDTRGREISAACGQLAAEGG
MSMEG_2545|M.smegmatis_MC2_155 ERGVSCTVRDTRGREIAAACGQLAAEG-
TH_0274|M.thermoresistible__bu ACGVPCTVRDTRGREIAAACGQLAADG-
MAB_3175c|M.abscessus_ATCC_199 EQGVSCTVRDTRGREIAAACGQLAASER
**.***********:********