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M. thermoresistible (build 8) TH_0059 (pfkA)

annotation: PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)
coordinates: 113448 - 114479
length: 344

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0059pfkA-100% (344)PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3035cpfkA1e-17788.05% (343) 6-phosphofructokinase
M. gilvum PYR-GCKMflv_4245-1e-17988.63% (343) 6-phosphofructokinase
M. tuberculosis H37RvRv3010cpfkA1e-17788.05% (343) 6-phosphofructokinase
M. leprae Br4923MLBr_01701pfkA1e-17686.59% (343) 6-phosphofructokinase
M. abscessus ATCC 19977MAB_3335c-1e-17284.84% (343) 6-phosphofructokinase
M. marinum MMMAR_1703pfkA1e-18089.50% (343) 6-phosphofructokinase PfkA
M. avium 104MAV_3858-0.089.21% (343) 6-phosphofructokinase
M. smegmatis MC2 155-----
M. ulcerans Agy99MUL_1940pfkA0.089.50% (343) 6-phosphofructokinase
M. vanbaalenii PYR-1Mvan_2116-0.090.96% (343) 6-phosphofructokinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4245|M.gilvum_PYR-GCK          MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFLDGWRGLLEDRRV
Mvan_2116|M.vanbaalenii_PYR-1       MRIGVLTGGGDCPGLNAVIRAVVRTSYVRYGSSVVGFQDGWRGLLEDRRI
TH_0059|M.thermoresistible__bu      MRIGVLTGGGDCPGLNAVIRAVVRTCDVRYGSSVVGFRDGWRGLLENRRV
MMAR_1703|M.marinum_M               MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFQDGWRGLLENRRL
MUL_1940|M.ulcerans_Agy99           MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFQDGWRGLLENRRL
Mb3035c|M.bovis_AF2122/97           MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRV
Rv3010c|M.tuberculosis_H37Rv        MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRV
MLBr_01701|M.leprae_Br4923          MRIGILTGGGDCPGLNAVIRAIVRTCDARYGSSVVGFQDGWRGLLENRRM
MAV_3858|M.avium_104                MRIGVLTGGGDCPGLNAVIRAVVRTCDSRYGSSVVGFQDGWRGLLENRRI
MAB_3335c|M.abscessus_ATCC_199      MRIGVLTGGGDCPGLNAVIRAVVRTCANRYNSQVVGFQDGWRGLLENRRI
                                    ****:****************:***.  **.*.**** :*:*****:**:

Mflv_4245|M.gilvum_PYR-GCK          QLKNDDRNDRLLAKGGTMLGTARTNPDKLRAGLDQIKQTLEDNGIDVLIP
Mvan_2116|M.vanbaalenii_PYR-1       QLSNDDRNDRLLAKGGTMLGTARVNPDKLRAGLDQIKQTLEDNGIDVLIP
TH_0059|M.thermoresistible__bu      QLRNDDRNDRLLAKGGTILGTARVHPEKLRAGLDQIKQTLDENGIDVLIP
MMAR_1703|M.marinum_M               QLRNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIKQTLDDNGIDVLIP
MUL_1940|M.ulcerans_Agy99           QLRNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIKQTLDDNGIDVLIP
Mb3035c|M.bovis_AF2122/97           QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIP
Rv3010c|M.tuberculosis_H37Rv        QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIP
MLBr_01701|M.leprae_Br4923          QLCNDDRNDRLLAKGGTMLGTAHVHPDKLRAGLHQIKQTLDDNGIDVLIP
MAV_3858|M.avium_104                QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLNQIKQTLDDNGIDVLIP
MAB_3335c|M.abscessus_ATCC_199      HLHNDDRNDRLLTKGGTVLGTARTNPDRLRAGLDQIKQTLDDNGIDVLIP
                                    :* *********:****:****:.:*::***** ** ***::********

Mflv_4245|M.gilvum_PYR-GCK          IGGEGTLTAAHWLSEEGVPVVGVPKTIDNDIDCTDVTFGHDTALTIATEA
Mvan_2116|M.vanbaalenii_PYR-1       IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
TH_0059|M.thermoresistible__bu      IGGEGTLTAARWLSDENVPVVGVPKTIDNDIDCTDQTFGHDTAVTVASEA
MMAR_1703|M.marinum_M               IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALMVATEA
MUL_1940|M.ulcerans_Agy99           IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALMVATEA
Mb3035c|M.bovis_AF2122/97           IGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
Rv3010c|M.tuberculosis_H37Rv        IGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
MLBr_01701|M.leprae_Br4923          IGGEGTLTAAHWLSQEDVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
MAV_3858|M.avium_104                IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATDA
MAB_3335c|M.abscessus_ATCC_199      IGGEGTLTAASWLADENVPVVGVPKTIDNDIDCTDVTFGFDTALTIATEA
                                    ********** **::*.****************** ***.***: :*::*

Mflv_4245|M.gilvum_PYR-GCK          IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGMASGAHMTLIPEQPFDVE
Mvan_2116|M.vanbaalenii_PYR-1       IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDVE
TH_0059|M.thermoresistible__bu      IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHLILIPEQPFDVE
MMAR_1703|M.marinum_M               IDRLHSTAESHQRVMLVEVMGRHAGWIALNSGLASGAHMTLIPEQPFDIE
MUL_1940|M.ulcerans_Agy99           IDRLHSTAESHQRVMLVEVMGRHAGWIALNSGLASGAHMTLIPEQPFDIE
Mb3035c|M.bovis_AF2122/97           IDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIE
Rv3010c|M.tuberculosis_H37Rv        IDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIE
MLBr_01701|M.leprae_Br4923          IDRLHSTAESHQRVMLVEVMGRHAGWIALSSGLASGAHMTLIPEQPFDVE
MAV_3858|M.avium_104                IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDVE
MAB_3335c|M.abscessus_ATCC_199      IDRLHSTAESHQRVMLVEVMGRHAGWIALHAGLASGAHMTLIPEVPFDVD
                                    ***********:***************** :*:*****: **** ***::

Mflv_4245|M.gilvum_PYR-GCK          EVCRLVKQRFQRGDSHFICVVAEGAKPAEGSMQLRQGGMDEFGHEKFTGV
Mvan_2116|M.vanbaalenii_PYR-1       EVCRLVKQRFVRGDSHFICVVAEGAKPAEGSMQLRQGGIDEFGHEKFTGV
TH_0059|M.thermoresistible__bu      EVCRLIRQRFVRGDSHFICVVAEGAKPAPGSMQLREGGVDEFGHERFTGV
MMAR_1703|M.marinum_M               EVCRLVKQRFQRGDSHFICVVAEGAKPVSGSMQLREGGLDEFGHERFTGV
MUL_1940|M.ulcerans_Agy99           EVCRLVKQRFQRGDSHFICVVAEGAKPVSGSMQLREGGLDEFGHERFTGV
Mb3035c|M.bovis_AF2122/97           EVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGV
Rv3010c|M.tuberculosis_H37Rv        EVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGV
MLBr_01701|M.leprae_Br4923          EVCCLVKRRFQRGDSHFICVVAEGAKPVPGSITLRQGGMDEFGHERFTGV
MAV_3858|M.avium_104                EVCRLVKRRFQRGDSHFICVVAEGAKPIPGSISLREGGIDEFGHERFTGV
MAB_3335c|M.abscessus_ATCC_199      EVCRLIKGRFQRGDSHFICVVAEGAKPAEGSMELRDGGIDEFGHQRFTGV
                                    *** *:: ** ****************  *:: **:**:*****::****

Mflv_4245|M.gilvum_PYR-GCK          AAQLAIEVEKRIKKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADAAH
Mvan_2116|M.vanbaalenii_PYR-1       AQQLAIEVEKRINKEVRVTVLGHVQRGGTPTAYDRVLATRFGVNAADAAH
TH_0059|M.thermoresistible__bu      AQQLALEVEKRINKEVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADAAH
MMAR_1703|M.marinum_M               AAQLGWEVEKRINKDVRVTVLGHVQRGGQPTAYDRVLATRFGVNAADAAH
MUL_1940|M.ulcerans_Agy99           AAQLGWEVEKRINKDVRVTVLGHVQRGGQPTAYDRVLATRFGVNAADAAH
Mb3035c|M.bovis_AF2122/97           AAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAH
Rv3010c|M.tuberculosis_H37Rv        AAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAH
MLBr_01701|M.leprae_Br4923          AAQLGAEVEKRINKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADASH
MAV_3858|M.avium_104                AAQLGAEVEKRINKEVRVTVLGHVQRGGTPTAYDRVLATRFGVNAADAAH
MAB_3335c|M.abscessus_ATCC_199      AQQLGVEIEKRINKEVRTTVLGHVQRGGTPTPFDRVLATRFGVNAADAAH
                                    * **. *:****:*:**.*****:**** **.:***************:*

Mflv_4245|M.gilvum_PYR-GCK          AGEYGMMVSARGTEIGRVPLADAVRQLKLVPQTRYDDAAEFFG
Mvan_2116|M.vanbaalenii_PYR-1       AGEYGMMVSLRGQEIGRVPLADAVRQLKLVPQSRYDDAAEFFG
TH_0059|M.thermoresistible__bu      AGEYGMMVALRGQEIVRVSLADATRNLKLVPQSRYDDAAEFFG
MMAR_1703|M.marinum_M               AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPQSRYDDAAEFFG
MUL_1940|M.ulcerans_Agy99           AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPQSRYDDAAEFFG
Mb3035c|M.bovis_AF2122/97           AGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG
Rv3010c|M.tuberculosis_H37Rv        AGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG
MLBr_01701|M.leprae_Br4923          AGEYGQMVSLRGQDIGRVPLEDAVRQLKLVPESRYDDAAAFFG
MAV_3858|M.avium_104                AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPESRYDDAAAFFG
MAB_3335c|M.abscessus_ATCC_199      AGEFGVMVSLRGQDIGRVPLAEATRQLKLVPKNRYEDAAAFFG
                                    ***:* **: ** :* **.* :*.*:*****:.**:*** ***