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RIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRVQLHNDDRNDRLLAKGGTMLGT ARVHPDKLRAGLPQIMQTLDDNGIDVLIPIGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHD TALTVATEAIDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIEEVCRLVKGRFQ RGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGVAAQLAVEVEKRINKDVRVTVLGHIQRGGTPT AYDRVLATRFGVNAADAAHAGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3010c | pfkA | - | 100% (343) | 6-phosphofructokinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3035c | pfkA | 0.0 | 100.00% (343) | 6-phosphofructokinase |
| M. gilvum PYR-GCK | Mflv_4245 | - | 1e-180 | 89.21% (343) | 6-phosphofructokinase |
| M. leprae Br4923 | MLBr_01701 | pfkA | 0.0 | 90.38% (343) | 6-phosphofructokinase |
| M. abscessus ATCC 19977 | MAB_3335c | - | 1e-175 | 85.71% (343) | 6-phosphofructokinase |
| M. marinum M | MMAR_1703 | pfkA | 0.0 | 93.29% (343) | 6-phosphofructokinase PfkA |
| M. avium 104 | MAV_3858 | - | 0.0 | 93.29% (343) | 6-phosphofructokinase |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0059 | pfkA | 1e-177 | 88.05% (343) | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) |
| M. ulcerans Agy99 | MUL_1940 | pfkA | 0.0 | 93.29% (343) | 6-phosphofructokinase |
| M. vanbaalenii PYR-1 | Mvan_2116 | - | 0.0 | 90.38% (343) | 6-phosphofructokinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4245|M.gilvum_PYR-GCK MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFLDGWRGLLEDRRV
Mvan_2116|M.vanbaalenii_PYR-1 MRIGVLTGGGDCPGLNAVIRAVVRTSYVRYGSSVVGFQDGWRGLLEDRRI
TH_0059|M.thermoresistible__bu MRIGVLTGGGDCPGLNAVIRAVVRTCDVRYGSSVVGFRDGWRGLLENRRV
Rv3010c|M.tuberculosis_H37Rv MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRV
Mb3035c|M.bovis_AF2122/97 MRIGVLTGGGDCPGLNAVIRAVVRTCHARYGSSVVGFQNGFRGLLENRRV
MMAR_1703|M.marinum_M MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFQDGWRGLLENRRL
MUL_1940|M.ulcerans_Agy99 MRIGVLTGGGDCPGLNAVIRAVVRTCDARYGSSVVGFQDGWRGLLENRRL
MLBr_01701|M.leprae_Br4923 MRIGILTGGGDCPGLNAVIRAIVRTCDARYGSSVVGFQDGWRGLLENRRM
MAV_3858|M.avium_104 MRIGVLTGGGDCPGLNAVIRAVVRTCDSRYGSSVVGFQDGWRGLLENRRI
MAB_3335c|M.abscessus_ATCC_199 MRIGVLTGGGDCPGLNAVIRAVVRTCANRYNSQVVGFQDGWRGLLENRRI
****:****************:***. **.*.**** :*:*****:**:
Mflv_4245|M.gilvum_PYR-GCK QLKNDDRNDRLLAKGGTMLGTARTNPDKLRAGLDQIKQTLEDNGIDVLIP
Mvan_2116|M.vanbaalenii_PYR-1 QLSNDDRNDRLLAKGGTMLGTARVNPDKLRAGLDQIKQTLEDNGIDVLIP
TH_0059|M.thermoresistible__bu QLRNDDRNDRLLAKGGTILGTARVHPEKLRAGLDQIKQTLDENGIDVLIP
Rv3010c|M.tuberculosis_H37Rv QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIP
Mb3035c|M.bovis_AF2122/97 QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIMQTLDDNGIDVLIP
MMAR_1703|M.marinum_M QLRNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIKQTLDDNGIDVLIP
MUL_1940|M.ulcerans_Agy99 QLRNDDRNDRLLAKGGTMLGTARVHPDKLRAGLPQIKQTLDDNGIDVLIP
MLBr_01701|M.leprae_Br4923 QLCNDDRNDRLLAKGGTMLGTAHVHPDKLRAGLHQIKQTLDDNGIDVLIP
MAV_3858|M.avium_104 QLHNDDRNDRLLAKGGTMLGTARVHPDKLRAGLNQIKQTLDDNGIDVLIP
MAB_3335c|M.abscessus_ATCC_199 HLHNDDRNDRLLTKGGTVLGTARTNPDRLRAGLDQIKQTLDDNGIDVLIP
:* *********:****:****:.:*::***** ** ***::********
Mflv_4245|M.gilvum_PYR-GCK IGGEGTLTAAHWLSEEGVPVVGVPKTIDNDIDCTDVTFGHDTALTIATEA
Mvan_2116|M.vanbaalenii_PYR-1 IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
TH_0059|M.thermoresistible__bu IGGEGTLTAARWLSDENVPVVGVPKTIDNDIDCTDQTFGHDTAVTVASEA
Rv3010c|M.tuberculosis_H37Rv IGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
Mb3035c|M.bovis_AF2122/97 IGGEGTLTAASWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
MMAR_1703|M.marinum_M IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALMVATEA
MUL_1940|M.ulcerans_Agy99 IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALMVATEA
MLBr_01701|M.leprae_Br4923 IGGEGTLTAAHWLSQEDVPVVGVPKTIDNDIDCTDVTFGHDTALTVATEA
MAV_3858|M.avium_104 IGGEGTLTAAHWLSEENVPVVGVPKTIDNDIDCTDVTFGHDTALTVATDA
MAB_3335c|M.abscessus_ATCC_199 IGGEGTLTAASWLADENVPVVGVPKTIDNDIDCTDVTFGFDTALTIATEA
********** **::*.****************** ***.***: :*::*
Mflv_4245|M.gilvum_PYR-GCK IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGMASGAHMTLIPEQPFDVE
Mvan_2116|M.vanbaalenii_PYR-1 IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDVE
TH_0059|M.thermoresistible__bu IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHLILIPEQPFDVE
Rv3010c|M.tuberculosis_H37Rv IDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIE
Mb3035c|M.bovis_AF2122/97 IDRLHSTAESHERVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDIE
MMAR_1703|M.marinum_M IDRLHSTAESHQRVMLVEVMGRHAGWIALNSGLASGAHMTLIPEQPFDIE
MUL_1940|M.ulcerans_Agy99 IDRLHSTAESHQRVMLVEVMGRHAGWIALNSGLASGAHMTLIPEQPFDIE
MLBr_01701|M.leprae_Br4923 IDRLHSTAESHQRVMLVEVMGRHAGWIALSSGLASGAHMTLIPEQPFDVE
MAV_3858|M.avium_104 IDRLHSTAESHQRVMLVEVMGRHAGWIALNAGLASGAHMTLIPEQPFDVE
MAB_3335c|M.abscessus_ATCC_199 IDRLHSTAESHQRVMLVEVMGRHAGWIALHAGLASGAHMTLIPEVPFDVD
***********:***************** :*:*****: **** ***::
Mflv_4245|M.gilvum_PYR-GCK EVCRLVKQRFQRGDSHFICVVAEGAKPAEGSMQLRQGGMDEFGHEKFTGV
Mvan_2116|M.vanbaalenii_PYR-1 EVCRLVKQRFVRGDSHFICVVAEGAKPAEGSMQLRQGGIDEFGHEKFTGV
TH_0059|M.thermoresistible__bu EVCRLIRQRFVRGDSHFICVVAEGAKPAPGSMQLREGGVDEFGHERFTGV
Rv3010c|M.tuberculosis_H37Rv EVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGV
Mb3035c|M.bovis_AF2122/97 EVCRLVKGRFQRGDSHFICVVAEGAKPAPGTIMLREGGLDEFGHERFTGV
MMAR_1703|M.marinum_M EVCRLVKQRFQRGDSHFICVVAEGAKPVSGSMQLREGGLDEFGHERFTGV
MUL_1940|M.ulcerans_Agy99 EVCRLVKQRFQRGDSHFICVVAEGAKPVSGSMQLREGGLDEFGHERFTGV
MLBr_01701|M.leprae_Br4923 EVCCLVKRRFQRGDSHFICVVAEGAKPVPGSITLRQGGMDEFGHERFTGV
MAV_3858|M.avium_104 EVCRLVKRRFQRGDSHFICVVAEGAKPIPGSISLREGGIDEFGHERFTGV
MAB_3335c|M.abscessus_ATCC_199 EVCRLIKGRFQRGDSHFICVVAEGAKPAEGSMELRDGGIDEFGHQRFTGV
*** *:: ** **************** *:: **:**:*****::****
Mflv_4245|M.gilvum_PYR-GCK AAQLAIEVEKRIKKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADAAH
Mvan_2116|M.vanbaalenii_PYR-1 AQQLAIEVEKRINKEVRVTVLGHVQRGGTPTAYDRVLATRFGVNAADAAH
TH_0059|M.thermoresistible__bu AQQLALEVEKRINKEVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADAAH
Rv3010c|M.tuberculosis_H37Rv AAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAH
Mb3035c|M.bovis_AF2122/97 AAQLAVEVEKRINKDVRVTVLGHIQRGGTPTAYDRVLATRFGVNAADAAH
MMAR_1703|M.marinum_M AAQLGWEVEKRINKDVRVTVLGHVQRGGQPTAYDRVLATRFGVNAADAAH
MUL_1940|M.ulcerans_Agy99 AAQLGWEVEKRINKDVRVTVLGHVQRGGQPTAYDRVLATRFGVNAADAAH
MLBr_01701|M.leprae_Br4923 AAQLGAEVEKRINKDVRVTVLGHVQRGGTPTAFDRVLATRFGVNAADASH
MAV_3858|M.avium_104 AAQLGAEVEKRINKEVRVTVLGHVQRGGTPTAYDRVLATRFGVNAADAAH
MAB_3335c|M.abscessus_ATCC_199 AQQLGVEIEKRINKEVRTTVLGHVQRGGTPTPFDRVLATRFGVNAADAAH
* **. *:****:*:**.*****:**** **.:***************:*
Mflv_4245|M.gilvum_PYR-GCK AGEYGMMVSARGTEIGRVPLADAVRQLKLVPQTRYDDAAEFFG
Mvan_2116|M.vanbaalenii_PYR-1 AGEYGMMVSLRGQEIGRVPLADAVRQLKLVPQSRYDDAAEFFG
TH_0059|M.thermoresistible__bu AGEYGMMVALRGQEIVRVSLADATRNLKLVPQSRYDDAAEFFG
Rv3010c|M.tuberculosis_H37Rv AGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG
Mb3035c|M.bovis_AF2122/97 AGEYGQMVTLRGQDIGRVPLADAVRKLKLVPQSRYDDAAAFFG
MMAR_1703|M.marinum_M AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPQSRYDDAAEFFG
MUL_1940|M.ulcerans_Agy99 AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPQSRYDDAAEFFG
MLBr_01701|M.leprae_Br4923 AGEYGQMVSLRGQDIGRVPLEDAVRQLKLVPESRYDDAAAFFG
MAV_3858|M.avium_104 AGEYGQMVSLRGQDIGRVPLADAVRQLKLVPESRYDDAAAFFG
MAB_3335c|M.abscessus_ATCC_199 AGEFGVMVSLRGQDIGRVPLAEATRQLKLVPKNRYEDAAAFFG
***:* **: ** :* **.* :*.*:*****:.**:*** ***