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M. thermoresistible (build 8) TH_0040 (-)

annotation: conserved hypothetical protein
coordinates: 82657 - 83157
length: 167

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0040--100% (167)conserved hypothetical protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0591-3e-0529.94% (157) ArsR family transcriptional regulator
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0576-2e-0529.94% (157) ArsR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4140-1e-0627.27% (132) hypothetical protein MAB_4140
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_4176-2e-6065.62% (160) hypothetical protein MSMEG_4176
M. ulcerans Agy99MUL_0693-4e-0530.77% (156) transcriptional regulator
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0591|M.bovis_AF2122/97            MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGL
Rv0576|M.tuberculosis_H37Rv         MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGL
MUL_0693|M.ulcerans_Agy99           --------------------------MNSPESLDSGYEPAPPGRPAET--
TH_0040|M.thermoresistible__bu      -------------------------------------MTERAGRISIE--
MSMEG_4176|M.smegmatis_MC2_155      -------------------------------------MTDREGKLTIE--
MAB_4140|M.abscessus_ATCC_1997      -------------------------------------MTNPLDATLAP--
                                                                          .   .       

Mb0591|M.bovis_AF2122/97            VTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGD
Rv0576|M.tuberculosis_H37Rv         VTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGD
MUL_0693|M.ulcerans_Agy99           ----------------------------------------------VSGE
TH_0040|M.thermoresistible__bu      -----------------------------------------------GDR
MSMEG_4176|M.smegmatis_MC2_155      -----------------------------------------------GDL
MAB_4140|M.abscessus_ATCC_1997      -------------------------------------------CEDHEGR
                                                                                    . 

Mb0591|M.bovis_AF2122/97            CAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTV
Rv0576|M.tuberculosis_H37Rv         CAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTV
MUL_0693|M.ulcerans_Agy99           RAMPLENAVVLPVDPAQSFALFTRPEGLRRWMAITARIEPYDAGVYRWTV
TH_0040|M.thermoresistible__bu      AVLTFERRLPFPVH--AVWQAITDPVQRTQWMGATT-IDPREGGVIETVP
MSMEG_4176|M.smegmatis_MC2_155      AVLRFERRLPYPVE--AVWAAITDPQQRGQWLGETT-IDAREGGRIEMIP
MAB_4140|M.abscessus_ATCC_1997      WVLTMSRDLNHPPE--KVWPWLVDPDRLRQWSPAIPDRPLDSAGPANVQE
                                     .: :.. :  * .    :  :. *    :*    .      .*  .   

Mb0591|M.bovis_AF2122/97            TPG------HSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTP
Rv0576|M.tuberculosis_H37Rv         TPG------HSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTP
MUL_0693|M.ulcerans_Agy99           TPG------HTAVGAVVEADPGQRLVLSWGWEGHGDPAPGESTVTVTLAP
TH_0040|M.thermoresistible__bu      TGPPYPPEMKKMTGRIRVWDPPH--VFEHEWNQQVV-EPG--VVRFELTP
MSMEG_4176|M.smegmatis_MC2_155      DGPGVPTEHKKMTGRIRVWDPPR--VFEHEWHQPILAETG--SVRYELTP
MAB_4140|M.abscessus_ATCC_1997      TSAD-----PVLDGEVLTVDPPRELIHRWGPE---------DTLRWRIEP
                                                 * :   ** :  :     .           :   : *

Mb0591|M.bovis_AF2122/97            VDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQHGDAGPDEWAAA
Rv0576|M.tuberculosis_H37Rv         VDGGTEVRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQRGDAGPDEWAAA
MUL_0693|M.ulcerans_Agy99           APDGTEIRLVHEGLTEQQAARHAEGWSHYLDRLVAAALQGDAGPDEWGAV
TH_0040|M.thermoresistible__bu      DGDGTLLRFTHRGLGVDNAYGFGPGTHAYLDRLEAH-LTGAAPPN-WSAR
MSMEG_4176|M.smegmatis_MC2_155      DGEGTVLRFTHRGLTPRDGQGFLPGTHAFFDRMEAY-LAGEPLPD-WATR
MAB_4140|M.abscessus_ATCC_1997      TDTGCRLTLEHSMADRGHAAGNAGGWHICLDTLSLA-VAGTPRGRVVGMD
                                       *  : : *      ..     *    :* :      * .     .  

Mb0591|M.bovis_AF2122/97            PDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRS
Rv0576|M.tuberculosis_H37Rv         PDPLDELSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRS
MUL_0693|M.ulcerans_Agy99           PGPLDELSCAEATLAVVQHVLRALEPADLARQTPCSQYDVVQLADHLMRS
TH_0040|M.thermoresistible__bu      YDRIAHHYRKES--------------------------------------
MSMEG_4176|M.smegmatis_MC2_155      YQEVARSKNGGTNHA-----------------------------------
MAB_4140|M.abscessus_ATCC_1997      AMKYDWQSLNDRYTEILTIN------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            LAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSN
Rv0576|M.tuberculosis_H37Rv         LAIIGAAAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSN
MUL_0693|M.ulcerans_Agy99           LTIIGGAAGAQLPPRDLDAPLETQVADAGQAVLEAWRRRGVDGTVELNAN
TH_0040|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4176|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4140|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            QVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITP
Rv0576|M.tuberculosis_H37Rv         QVPATVPVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITP
MUL_0693|M.ulcerans_Agy99           QVPAAVPVGILCLELLVHAWDFAFATDRRVVVSDTVTEYVLTVAGKVITP
TH_0040|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4176|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4140|M.abscessus_ATCC_1997      --------------------------------------------------
                                                                                      

Mb0591|M.bovis_AF2122/97            ATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPT--AGHVSAT------
Rv0576|M.tuberculosis_H37Rv         ATRNSAGFAAPAAVGSFAPVLDRLIAFTGRQPT--AGHVSAT------
MUL_0693|M.ulcerans_Agy99           AARNSAGFAAPVAVGAFAPVLDRLIAFTGRRPVHPTGLTSPIRADPGS
TH_0040|M.thermoresistible__bu      ------------------------------------------------
MSMEG_4176|M.smegmatis_MC2_155      ------------------------------------------------
MAB_4140|M.abscessus_ATCC_1997      ------------------------------------------------