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M. thermoresistible (build 8) TH_0032 (rpoA)

annotation: PROBABLE DNA-DIRECTED RNA POLYMERASE (ALPHA CHAIN) RPOA (TRANSCRIPTASE ALPHA CHAIN) (RNA POLYMERASE ALPHA SUBUNIT) (DNA-DIRECTED RNA NUCLEOTIDYLTRANSFERASE)
coordinates: 72161 - 73216
length: 352

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_0032 rpoA - 100% (352) PROBABLE DNA-DIRECTED RNA POLYMERASE (ALPHA CHAIN) RPOA (TRANSCRIPTASE ALPHA CHAIN) (RNA POLYMERASE ALPHA SUBUNIT) (DNA-DIRECTED RNA NUCLEOTIDYLTRANSFERASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3486c rpoA 1e-179 90.31% (351) DNA-directed RNA polymerase subunit alpha
M. gilvum PYR-GCK Mflv_4970 - 0.0 91.24% (354) DNA-directed RNA polymerase subunit alpha
M. tuberculosis H37Rv Rv3457c rpoA 1e-179 90.31% (351) DNA-directed RNA polymerase subunit alpha
M. leprae Br4923 MLBr_01957 rpoA 1e-176 88.60% (351) DNA-directed RNA polymerase subunit alpha
M. abscessus ATCC 19977 MAB_3770c - 0.0 91.74% (351) DNA-directed RNA polymerase subunit alpha
M. marinum M MMAR_1090 rpoA 1e-179 90.60% (351) DNA-directed RNA polymerase (alpha chain), RpoA
M. avium 104 MAV_4398 rpoA 1e-179 90.03% (351) DNA-directed RNA polymerase subunit alpha
M. smegmatis MC2 155 MSMEG_1524 rpoA 0.0 90.31% (351) DNA-directed RNA polymerase subunit alpha
M. ulcerans Agy99 MUL_0848 rpoA 1e-179 90.60% (351) DNA-directed RNA polymerase subunit alpha
M. vanbaalenii PYR-1 Mvan_1436 - 0.0 91.17% (351) DNA-directed RNA polymerase subunit alpha

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1090|M.marinum_M               MLISQRPTLSEEVLTDSRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
MUL_0848|M.ulcerans_Agy99           MLISQRPTLSEEVLTDSRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
MAV_4398|M.avium_104                MLISQRPTLSEEVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
MLBr_01957|M.leprae_Br4923          MLISQRPTLSEDILTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
Mb3486c|M.bovis_AF2122/97           MLISQRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
Rv3457c|M.tuberculosis_H37Rv        MLISQRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
MAB_3770c|M.abscessus_ATCC_199      MLISQRPTLSEETLAENRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
Mflv_4970|M.gilvum_PYR-GCK          MLISQRPTLSEEVVAENRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
Mvan_1436|M.vanbaalenii_PYR-1       MLISQRPTLSEDVLAENRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
MSMEG_1524|M.smegmatis_MC2_155      MLISQRPTLSEETVAENRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAA
TH_0032|M.thermoresistible__bu      MLISQRPTLSEEPISEYRSRFIIEPLEPGFGYTLGNSLRRTLLSSIPGAA
                                    ***********: ::: **:*:****************************

MMAR_1090|M.marinum_M               VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKALVVSSEEDEPVTMYLRKQ
MUL_0848|M.ulcerans_Agy99           VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKALVVSSEEDEPVTMYLRKQ
MAV_4398|M.avium_104                VTSIRIDGVLHEFTTVPGVKEDVTAIILNLKSLVVSSEEDEPVTMYLRKQ
MLBr_01957|M.leprae_Br4923          VTSIRIDGVLHEFTTVPGVKEDVTEIILNLKGLVVSSEEDEPVTMYLRKQ
Mb3486c|M.bovis_AF2122/97           VTSIRIDGVLHEFTTVPGVKEDVTEIILNLKSLVVSSEEDEPVTMYLRKQ
Rv3457c|M.tuberculosis_H37Rv        VTSIRIDGVLHEFTTVPGVKEDVTEIILNLKSLVVSSEEDEPVTMYLRKQ
MAB_3770c|M.abscessus_ATCC_199      VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKSLVVSSEEDEPVTMYLRKQ
Mflv_4970|M.gilvum_PYR-GCK          VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSEEDEPVTMYLRKQ
Mvan_1436|M.vanbaalenii_PYR-1       VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSEEDEPVTMYLRKQ
MSMEG_1524|M.smegmatis_MC2_155      VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSDDDEPVTMYLRKQ
TH_0032|M.thermoresistible__bu      VTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSEEDEPVTMYLRKQ
                                    ************************ ******.*****::***********

MMAR_1090|M.marinum_M               GPGEVTAGDIVPPAGVTVHNPNMRIATLNDKGKLEVELVVERGRGYVPAV
MUL_0848|M.ulcerans_Agy99           GPGEVTAGDIVPPAGVTVHNPNMRIATLNDKGKLEVELVVERGRGYVPAV
MAV_4398|M.avium_104                GPGEVTAGDIVPPAGVTVHNPELHIATLNDKGKLEVELVVERGRGYVPAV
MLBr_01957|M.leprae_Br4923          GPGEVTAGDIVPPAGVTLHNPGMRIATLNDKGKIEAELVVERGRGYVPAV
Mb3486c|M.bovis_AF2122/97           GPGEVTAGDIVPPAGVTVHNPGMHIATLNDKGKLEVELVVERGRGYVPAV
Rv3457c|M.tuberculosis_H37Rv        GPGEVTAGDIVPPAGVTVHNPGMHIATLNDKGKLEVELVVERGRGYVPAV
MAB_3770c|M.abscessus_ATCC_199      GPGAVTAGDIVPPAGVTVHNPDMHIATLNDKGKLEIELVVERGRGYVPAV
Mflv_4970|M.gilvum_PYR-GCK          GPGEVTAGDIVPPAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAV
Mvan_1436|M.vanbaalenii_PYR-1       GPGEVTAGDIVPPAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAV
MSMEG_1524|M.smegmatis_MC2_155      GPGVVTAGDIVPPAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAV
TH_0032|M.thermoresistible__bu      GPGEVTAADIVPPAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAV
                                    *** ***.*********:*** ::*********:* **************

MMAR_1090|M.marinum_M               QNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKN
MUL_0848|M.ulcerans_Agy99           QNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKN
MAV_4398|M.avium_104                QNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKS
MLBr_01957|M.leprae_Br4923          QNRALGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKS
Mb3486c|M.bovis_AF2122/97           QNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKN
Rv3457c|M.tuberculosis_H37Rv        QNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKN
MAB_3770c|M.abscessus_ATCC_199      QNKASGAEIGRIPVDSIYSPVLKVTYNVEATRVEQRTDFDKLVLDVETKN
Mflv_4970|M.gilvum_PYR-GCK          QNKASGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLILDVETKN
Mvan_1436|M.vanbaalenii_PYR-1       QNKASGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLILDVETKN
MSMEG_1524|M.smegmatis_MC2_155      QNKASGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIIDVETKN
TH_0032|M.thermoresistible__bu      QNKASGAEIGRIPVDSIYSPVLKVTYNVEATRVEQRTDFDKLILDVETKP
                                    **:* *********************:*:*************::***** 

MMAR_1090|M.marinum_M               SITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
MUL_0848|M.ulcerans_Agy99           SITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
MAV_4398|M.avium_104                SITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
MLBr_01957|M.leprae_Br4923          SITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
Mb3486c|M.bovis_AF2122/97           SISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
Rv3457c|M.tuberculosis_H37Rv        SISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
MAB_3770c|M.abscessus_ATCC_199      SISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALP
Mflv_4970|M.gilvum_PYR-GCK          SISPRDALASAGKTLVELFGLARELNIEAEGIEIGPSPAEADQAAHFALP
Mvan_1436|M.vanbaalenii_PYR-1       SITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADQAAHFALP
MSMEG_1524|M.smegmatis_MC2_155      SISPRDALASAGGTLVELFGLARELNADSEHIEIGPSPAEADHIASFALP
TH_0032|M.thermoresistible__bu      SISPRDAVASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIAAFALP
                                    **:****:**** ************* ::* ***********: * ****

MMAR_1090|M.marinum_M               IDDLDLTVRSYNCLKREGVHTVGELVSRTESDLLDIRNFGQKSIDEVKVK
MUL_0848|M.ulcerans_Agy99           IDDLDLTVRSYNCLKREGVHTVGELVSRTESDLLDIRNFGQKSIDEVKVK
MAV_4398|M.avium_104                IDDLDLTVRSYNCLKREGVHTVGELVSRTESDLLDIRNFGQKSIDEVKVK
MLBr_01957|M.leprae_Br4923          IDDLDLTVRSYNCLKREGVHTVGELVSRTESDLLDIRNFGQKSIDEVKVK
Mb3486c|M.bovis_AF2122/97           IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
Rv3457c|M.tuberculosis_H37Rv        IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
MAB_3770c|M.abscessus_ATCC_199      IEDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
Mflv_4970|M.gilvum_PYR-GCK          IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
Mvan_1436|M.vanbaalenii_PYR-1       IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
MSMEG_1524|M.smegmatis_MC2_155      IDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIK
TH_0032|M.thermoresistible__bu      IDDLDLTVRSYNCLKREGIHTVGELVARTESDLLDIRNFGQKSIDEVKVK
                                    *:****************:*******:*********************:*

MMAR_1090|M.marinum_M               LHQLGLSLKDSPPSFDPSEVAGYDVATGTWS-TEGAYD-------DQDYA
MUL_0848|M.ulcerans_Agy99           LHQLGLSLKDSPPSFDPSEVAGYDVATGTWS-TEGAYD-------DQDYA
MAV_4398|M.avium_104                LHQLGLSLKDSPPSFDPSQVAGYDVATGTWS-TEAAYD-------DQDYA
MLBr_01957|M.leprae_Br4923          LHQLGLSLKDSPDSFDPSEVAGYDVTTGTWS-TDGAYD-------SQDYA
Mb3486c|M.bovis_AF2122/97           LHQLGLSLKDSPPSFDPSEVAGYDVATGTWS-TEGAYD-------EQDYA
Rv3457c|M.tuberculosis_H37Rv        LHQLGLSLKDSPPSFDPSEVAGYDVATGTWS-TEGAYD-------EQDYA
MAB_3770c|M.abscessus_ATCC_199      LHQLGLSLKDSPTSFDPSEVAGYDVATGTWS-DTGSYDF----DGDQDFA
Mflv_4970|M.gilvum_PYR-GCK          LHQLGLSLKDSPASFDPSEVAGYDVATGTWN-SDAGYDSGYEADDNQDYA
Mvan_1436|M.vanbaalenii_PYR-1       LHQLGLSLKDSPASFDPSEVAGYDVATGTWN-SDAGYD----LEDNQDYA
MSMEG_1524|M.smegmatis_MC2_155      LHQLGLSLKDSPATFDPSEVAGYDAATGTWT-SDAGYD----LDDNQDYA
TH_0032|M.thermoresistible__bu      LHQLGLSLKDSPAGFDPSQVAGYDASSGTWSNETGGYEQ----DNDQDYA
                                    ************  ****:*****.::***.   ..*:       .**:*

MMAR_1090|M.marinum_M               ETEQL
MUL_0848|M.ulcerans_Agy99           ETEQL
MAV_4398|M.avium_104                ETEQL
MLBr_01957|M.leprae_Br4923          ETEQL
Mb3486c|M.bovis_AF2122/97           ETEQL
Rv3457c|M.tuberculosis_H37Rv        ETEQL
MAB_3770c|M.abscessus_ATCC_199      ETEQL
Mflv_4970|M.gilvum_PYR-GCK          ETEQL
Mvan_1436|M.vanbaalenii_PYR-1       ETEQL
MSMEG_1524|M.smegmatis_MC2_155      ETEQL
TH_0032|M.thermoresistible__bu      ETEQL
                                    *****

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_0032	rpoA	-	100% (352)	PROBABLE DNA-DIRECTED RNA POLYMERASE (ALPHA CHAIN) RPOA (TRANSCRIPTASE ALPHA CHAIN) (RNA POLYMERASE ALPHA SUBUNIT) (DNA-DIRECTED RNA NUCLEOTIDYLTRANSFERASE)