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M. tuberculosis H37Rv Rv3921c (-)

annotation: putative inner membrane protein translocase component YidC
coordinates: 4408969 - 4410069
length: 366

SLLFDFFSLDFIYYPVSWIMWVWYRLFAFVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQE
LQPQIKALQKKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRTTGGFGQPHL
SVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRPALIAVGVPVMILAGIATYFN
SRASIARQSAEAAANPQTAMMNKLALYVFPLGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEE
EAKKQEAVRRRAANAPAPGAKPKRSPKTAPATNAAAPTEAGDTDDGAESDASTERPADTSNPARRNSGPS
ARTPRPGVRPKKRKR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3921c--100% (366)putative inner membrane protein translocase component YidC

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3952c-0.0100.00% (366) putative inner membrane protein translocase component YidC
M. gilvum PYR-GCKMflv_0831-1e-15674.06% (374) putative inner membrane protein translocase component YidC
M. leprae Br4923MLBr_02710-1e-17077.37% (380) putative inner membrane protein translocase component YidC
M. abscessus ATCC 19977MAB_4953coxaA1e-15272.75% (367) putative inner membrane protein translocase component YidC
M. marinum MMMAR_5485-0.085.22% (372) transmembrane protein
M. avium 104MAV_5310-1e-17783.75% (363) putative inner membrane protein translocase component YidC
M. smegmatis MC2 155MSMEG_6942-1e-15875.48% (367) putative inner membrane protein translocase component YidC
M. thermoresistible (build 8)TH_0761-1e-15672.73% (374) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_5074-0.084.41% (372) putative inner membrane protein translocase component YidC
M. vanbaalenii PYR-1Mvan_6075-1e-15875.47% (375) putative inner membrane protein translocase component YidC

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0831|M.gilvum_PYR-GCK          ---MSFNWMSLDFIYYPVSAIMWVWYKAFAFLLG-------PTNFFAWAL
Mvan_6075|M.vanbaalenii_PYR-1       ---MSFNWFSLDIIYYPVSAIMWVWYKAFAFLIGLIPGVDGPSNFFAWAL
MSMEG_6942|M.smegmatis_MC2_155      ----MFNFFSLDIIYYPVSAIMWVWYKAFSFLLG-------PTNFFAWAL
TH_0761|M.thermoresistible__bu      ----VFNWFSLDIIYYPVSGIMWIWYKVFAFLLG-------PSNFFAWAL
Rv3921c|M.tuberculosis_H37Rv        MSLL-FDFFSLDFIYYPVSWIMWVWYRLFAFVLG-------PSNFFAWAL
Mb3952c|M.bovis_AF2122/97           MSLL-FDFFSLDFIYYPVSWIMWVWYRLFAFVLG-------PSNFFAWAL
MMAR_5485|M.marinum_M               MSFL-FDFFSLDFVYYPVSWIMWVWYKLFALVLG-------PSNFFAWAL
MUL_5074|M.ulcerans_Agy99           MSFL-FDFFSLEFVYYPVSWIMWVWYKLFALVLG-------PSNFFAWAL
MLBr_02710|M.leprae_Br4923          MSLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLG-------PSNFFAWAL
MAV_5310|M.avium_104                ----MFDFFSLDFVYYPVSWIMWVWYKLFAAMLG-------PSNFFAWAL
MAB_4953c|M.abscessus_ATCC_199      ----MFDWFNLGFIYYPVSGIMWVWYKLFAYLLG-------PKNFFAWAL
                                         *::..* ::***** ***:**: *: ::*       *.*******

Mflv_0831|M.gilvum_PYR-GCK          SVMFLVFTLRAILYKPFVKQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
Mvan_6075|M.vanbaalenii_PYR-1       SVMFLVFTLRAILYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
MSMEG_6942|M.smegmatis_MC2_155      SVMFLVFTLRAILYKPFVKQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
TH_0761|M.thermoresistible__bu      SVMFLVFTLRAILYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
Rv3921c|M.tuberculosis_H37Rv        SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
Mb3952c|M.bovis_AF2122/97           SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
MMAR_5485|M.marinum_M               SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
MUL_5074|M.ulcerans_Agy99           SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
MLBr_02710|M.leprae_Br4923          SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPRIRALQRKYGKDRQRMAL
MAV_5310|M.avium_104                SVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMAL
MAB_4953c|M.abscessus_ATCC_199      SVMFLVFTLRAILYKPFVRQIRTTRQMQELQPQIKALQKKYKNDRQRMAL
                                    ***********:******:*************:*:***:** :*******

Mflv_0831|M.gilvum_PYR-GCK          EMQKLQREHGFNPILGCLPMLAQVPVFLGLYHTLMSFNRT-QTGIGRLGL
Mvan_6075|M.vanbaalenii_PYR-1       EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLMSFNRT-QTGIGRLGL
MSMEG_6942|M.smegmatis_MC2_155      EMQKLQKEHGFNPILGCLPMLAQVPVFLGLYHVLMSFNRT-QTGIGRLGL
TH_0761|M.thermoresistible__bu      EMQKLQKEHGFNPILGCLPMLAQIPVFIGLFHVLRSFNRTGGFGIGAQHL
Rv3921c|M.tuberculosis_H37Rv        EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRT-TGGFGQPHL
Mb3952c|M.bovis_AF2122/97           EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRT-TGGFGQPHL
MMAR_5485|M.marinum_M               EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRT-TGGFGQPHL
MUL_5074|M.ulcerans_Agy99           EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRT-TGGFGQPHL
MLBr_02710|M.leprae_Br4923          EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHALRSFNRT-TGGFGQPHM
MAV_5310|M.avium_104                EMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRT-TGGFGQPHL
MAB_4953c|M.abscessus_ATCC_199      EMQKLQREHGFNPILGCLPMLAQIPVFLGLFHVLRSFNRT-TGGFGQVHM
                                    ******:****************:***:**:*.* *****   *:*   :

Mflv_0831|M.gilvum_PYR-GCK          SVEENRQLGNYFFSATDVQHFLDANLFGAPLGATMIQQHGLDAFTEFNRT
Mvan_6075|M.vanbaalenii_PYR-1       SVEENRSLPNYFFSATDVGHFLDANLFGAPLGATMIQQHGLDAFTEFNRL
MSMEG_6942|M.smegmatis_MC2_155      SVEENRSLGNYVFSATDVQHFLDANLFGAPLGATMIQQHGLEAFTEFNRL
TH_0761|M.thermoresistible__bu      DPEVNRTLPNYFFSAEDVGHFLDANLFGAPIGAWMTQTSGLEAFTVFDRT
Rv3921c|M.tuberculosis_H37Rv        SVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRP
Mb3952c|M.bovis_AF2122/97           SVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRP
MMAR_5485|M.marinum_M               SVVENRLTGNYVFTPTDVGHFLDANLFGAPIGASMTQRGGLDAFVDFSRP
MUL_5074|M.ulcerans_Agy99           SVVENRLTGNYVFTPTDVGHFLDVNLFGAPIGASMTQRGGLDAFVDFSRP
MLBr_02710|M.leprae_Br4923          SVTENRMTGNYVFTPVDVGHFLDANLWGAPIGAYMTQRSGLDAFIDFSRP
MAV_5310|M.avium_104                SVVQNRLTGNYVFTPTDVGHFLDANLFGAPIGAFMTQRTGLDAFTYFSRP
MAB_4953c|M.abscessus_ATCC_199      TVEANRATGNYFFSANDVANFLDANLFGAPLGATMIQTTGLDAFTEFNRL
                                        **   **.*:. ** :***.**:***:** * *  **:**  *.* 

Mflv_0831|M.gilvum_PYR-GCK          SVIIVGVPIMILAGIATYFNSRASVARQSPEAAANPQTAMMNKLALYVFP
Mvan_6075|M.vanbaalenii_PYR-1       SVIVVGVPIMIMAGIATYFNSRASVARQSPEAAANPQTAMMNKLALYVFP
MSMEG_6942|M.smegmatis_MC2_155      AVIIVGVPIMILAGIATHFNSRASVARQSVEAAANPQTAMMNKLALYVFP
TH_0761|M.thermoresistible__bu      AVIAVGVPLMLAAGIATYFNSRASVARQSPEAAANPQTAIMNKLALYVFP
Rv3921c|M.tuberculosis_H37Rv        ALIAVGVPVMILAGIATYFNSRASIARQSAEAAANPQTAMMNKLALYVFP
Mb3952c|M.bovis_AF2122/97           ALIAVGVPVMILAGIATYFNSRASIARQSAEAAANPQTAMMNKLALYVFP
MMAR_5485|M.marinum_M               AVIAVGVPVMVLAGVATYFNSRASVARQSAEAAANPQTAMMNKLALYVFP
MUL_5074|M.ulcerans_Agy99           AVIAVGVPVMVLAGVATYFNSRASVARQSPEAAANPQTAMMNKLALYVFP
MLBr_02710|M.leprae_Br4923          AVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYVFP
MAV_5310|M.avium_104                AVIAVGLPVMILAGVATYFNSRASVARQSPEAAANPQTAMMNKLALYVFP
MAB_4953c|M.abscessus_ATCC_199      AVAGVSIPLMIIAGVATYFNSRASIARQSPEAQANPQTQIMNRLALYVFP
                                    ::  *.:*:*: **:**:******:**** **  **** :**::******

Mflv_0831|M.gilvum_PYR-GCK          LGVVVGGPFLPLAIIMYWLANNIWTFGQQHYVFGKIEKEEEQKKLEAIER
Mvan_6075|M.vanbaalenii_PYR-1       LGVVVGGPFLPLAIILYWFANNIWTFGQQHYVFGMIEKEEEQKKLEAIER
MSMEG_6942|M.smegmatis_MC2_155      LGVVVGGPFLPLAVIMYWLANNIWTYGQQHYVFGKIEKEEEAKKAEMLER
TH_0761|M.thermoresistible__bu      LGVVVGGPFLPIAIIIYWFANNIWTFGQQHYVFGMIEKEEQAKKEEALAR
Rv3921c|M.tuberculosis_H37Rv        LGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEEEAKKQEAVRR
Mb3952c|M.bovis_AF2122/97           LGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEEEAKKQEAVRR
MMAR_5485|M.marinum_M               LGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEEEAKKQEALER
MUL_5074|M.ulcerans_Agy99           LGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEEEAKKQEALER
MLBr_02710|M.leprae_Br4923          FGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIER
MAV_5310|M.avium_104                LGVVVGGPFLPLAIILYWFANNIWTFGQQHYVFGMIEKEDEAKKQEAIQR
MAB_4953c|M.abscessus_ATCC_199      LGVVVGGPFLPIAIILYWVSNNIWTFGQQHYVFNRIAKEEEEKKQADLER
                                    :**********:*:*:**.:*****:*******. * **:: **   : *

Mflv_0831|M.gilvum_PYR-GCK          RAANAPAPGAKPSRKKKATTDSESVESTTEIEDAEPVAESASGDS-ASAK
Mvan_6075|M.vanbaalenii_PYR-1       RAANAPAPGAKPSRKKKAGTDSAVAGPS----DGAAGAESAGIDE-APS-
MSMEG_6942|M.smegmatis_MC2_155      RAANAPAPGAKPNRMKKAQPGGQAGAEG----EAGSATELTGESS-GTSE
TH_0761|M.thermoresistible__bu      RAANAPAPGAKPSRARKAGGASGASAES------ATAAAAPGGEA-DTAE
Rv3921c|M.tuberculosis_H37Rv        RAANAPAPGAKPKRSPKTAPATNAAAP-----TEAGDTDDGAESD-----
Mb3952c|M.bovis_AF2122/97           RAANAPAPGAKPKRSPKTAPATNAAAP-----TEAGDTDDGAESD-----
MMAR_5485|M.marinum_M               RAANAPAPGAKPKRTPKAVAGSNGSPAESEDVSDTDATETSGEEA-----
MUL_5074|M.ulcerans_Agy99           RAANAPAPGPKPKRTPKAVAGSNGSPAESEDVSDTDATETSGEEA-----
MLBr_02710|M.leprae_Br4923          RTANAPAPGSKPKYVSTTAPVSVNGFSKDTMISDDGAKLGSQEADSIDWV
MAV_5310|M.avium_104                RAANAPAPGAKPKRNLKAGAG-------------NGVDADAAQSD-----
MAB_4953c|M.abscessus_ATCC_199      RAANAPKPGAKPTR-GKSQPAEQADDSD----ASPEVVESTGTDE-----
                                    *:**** **.**.   .:                                

Mflv_0831|M.gilvum_PYR-GCK          KTTPTAGSTPRNPNRSAAQGGTANRTPKPGAR----PKKKKR--
Mvan_6075|M.vanbaalenii_PYR-1       ETPPAAES----PTTSAAQGGASNRTPRPGAR----PKKRKR--
MSMEG_6942|M.smegmatis_MC2_155      PTTDSGAT----GASGTSGTTPTNRTPKPGAR----PKKRKR--
TH_0761|M.thermoresistible__bu      TGSDTRPTPKTKGSGGAGRAPKPGGTPRPGARSGSRPKKKKKKR
Rv3921c|M.tuberculosis_H37Rv        ---ASTERPADTSNPARRNSGPSARTPRPGVR----PKKRKR--
Mb3952c|M.bovis_AF2122/97           ---ASTERPADTSNPARRNSGPSARTPRPGVR----PKKRKR--
MMAR_5485|M.marinum_M               ---PSGDTKQDKPNSTARNSSPTNRTPRPGAR----PKKRKR--
MUL_5074|M.ulcerans_Agy99           ---PSGDTKRDKPNSTARNSSPTNRTPRPGVR----PKKRKR--
MLBr_02710|M.leprae_Br4923          TETKTATTPADKPDCVGYNNNPTSHTRRSGQR----TKRRKR--
MAV_5310|M.avium_104                --------AGATEGQAGGGSDAPSRTPRPGAR----PKKRKR--
MAB_4953c|M.abscessus_ATCC_199      ------DSGGPASPNSTNGSGTTSRTPKPGAR----PDRRRKR-
                                                          .  * :.* *    ..::::