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MTAEPEVRTLREVVLDQLGTAESRAYKMWLPPLTNPVPLNELIARDRRQPLRFALGIMDEPRRHLQDVWG VDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYCIDLGGGGLIYLENLPHVGGVANRSEP DKVNRVVAEMQAVMRQRETTFKEHRVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEG QVQDLAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDRITREIPANRPGRAVSMEK HHLMIGVPRFDGVHSADNLVEAITAGVTQIASQHTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEI PIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDT HLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPP MAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQ AFLVSPDGKEVIQAPYIEPPEEVFAAPPSAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3871 | - | - | 100% (591) | hypothetical protein Rv3871 |
| M. tuberculosis H37Rv | Rv3447c | - | 2e-99 | 35.32% (586) | hypothetical protein Rv3447c |
| M. tuberculosis H37Rv | Rv1784 | - | 1e-76 | 32.31% (616) | hypothetical protein Rv1784 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3901 | - | 0.0 | 100.00% (591) | hypothetical protein Mb3901 |
| M. gilvum PYR-GCK | Mflv_0770 | - | 0.0 | 73.07% (583) | cell divisionFtsK/SpoIIIE |
| M. leprae Br4923 | MLBr_00052 | - | 0.0 | 80.87% (596) | hypothetical protein MLBr_00052 |
| M. abscessus ATCC 19977 | MAB_3756c | - | 1e-114 | 38.05% (586) | putative FtsK/SpoIIIE family protein |
| M. marinum M | MMAR_5446 | - | 0.0 | 92.72% (591) | hypothetical protein MMAR_5446 |
| M. avium 104 | MAV_4390 | - | 1e-97 | 36.61% (579) | ftsk/SpoIIIE family protein |
| M. smegmatis MC2 155 | MSMEG_0062 | - | 0.0 | 77.70% (592) | ftsk/SpoIIIE family protein |
| M. thermoresistible (build 8) | TH_2902 | - | 0.0 | 76.84% (583) | PUTATIVE ftsk/spoiiie family protein |
| M. ulcerans Agy99 | MUL_0860 | - | 2e-92 | 34.84% (577) | hypothetical protein MUL_0860 |
| M. vanbaalenii PYR-1 | Mvan_0075 | - | 0.0 | 74.96% (583) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 MTQADIVVEAPPELPAPESTGLPARLLPVALSVAGIGVMTVVFASG----
MUL_0860|M.ulcerans_Agy99 -MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIATLIAMAATYVSG----
MAB_3756c|M.abscessus_ATCC_199 MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAMVGMIAFFVTSGSFGG
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ---GAAARQPAFLAFPATMLVSTVAAALIGRSR-RGGGGLDADRGRYLEY
MUL_0860|M.ulcerans_Agy99 ---APSARNPTMLVLPATMSLSLMVMAVSARGR-RRGAGLDQDRVGYLQY
MAB_3756c|M.abscessus_ATCC_199 GAGGGMMRSPMFMLFPIMMMVSMVSMVSNSGGKGAKTSEINEDRKDYLRY
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 LNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIGGPRMWRRRPTGPDFCV
MUL_0860|M.ulcerans_Agy99 LSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIGGSRMWERRPADADFCR
MAB_3756c|M.abscessus_ATCC_199 LEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAGGRRMWERRPGDSDYCH
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 VRVGMGVLPLARRVVAPPVPAEEVRDPVTATALRRFLHTHATVPG-PVTV
MUL_0860|M.ulcerans_Agy99 IRIGLGTQPLATRLVAAPLPPPHRSDPVTVSALRRFLEAHARVTDVPIAI
MAB_3756c|M.abscessus_ATCC_199 VRVGTGDQRLAAQLVAPEIGPVEELEPVASVALRRFVRTHSLVPELPIAL
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 DLGAGSPVTIDGDAGAARAVLRAVVCQLAVLHAPDRVGIAAVVGDGDRAH
MUL_0860|M.ulcerans_Agy99 ALHGAGVVTIGGDPARVRALLRAMVCQMAVLHGPDQLLVAAVVSDRNRPG
MAB_3756c|M.abscessus_ATCC_199 NLRGFAAVTIDGSPEVARGMLRAMICQLAMFHGPDQFLVAAVVNRHAAPH
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 WDWLKWLPHNRHPTHDDALGPMRMVYSTAAQAQQALAG--LPVARLVLVA
MUL_0860|M.ulcerans_Agy99 WEWLKWLPHNQHPSHHDEVGAERMVYPNITQASAAFDAVALPVMVIVDTD
MAB_3756c|M.abscessus_ATCC_199 WDWLKWLPHSQHPSAFDGVGTSRLVYHSLGEVEESLASLITERERFSRTA
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ERAVAPI-----------------------AGATVIAIGAGDD------G
MUL_0860|M.ulcerans_Agy99 EHGKQLP-----------------------AGVTVLEVGRGPD------G
MAB_3756c|M.abscessus_ATCC_199 QPSPDRPQILIVVDSGTLIGSERLIVDHGIDSVTLVEIGTRVDPLAARRG
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 APVTIRT-------AAGTVSPSRPDRMTAADALTCARRLAGQRV--TAGD
MUL_0860|M.ulcerans_Agy99 TQVVVKR-------AGETTTLTRPDELDQVSALVCARLLAPHRCGDRAGG
MAB_3756c|M.abscessus_ATCC_199 MQLELTERGLGAKGNVGSEVFAHPDHLTITEAMACARRLAPYRVLTGSGD
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 G-------DGGWPGLVGLADVSGFDPATLWGRQTGRDRLRAPLGVAADGT
MUL_0860|M.ulcerans_Agy99 H-------PGDWARMLGIGEIATYHPVSHWHKRNQRERLCVPIGATADGS
MAB_3756c|M.abscessus_ATCC_199 EVQIQTEVSTRWSDIVGIGDPGLLNPEVVWRNRVGRDRLRVPIGIAVDGT
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 PVELDIKEPAEHGMGPHGLCVGATGSGKSELLRTIALGMMARNSPDVLNL
MUL_0860|M.ulcerans_Agy99 PVLLDIKEPAARGMGPHGLCIGATGSGKSELLRTVALGMMVGNSPEVLNL
MAB_3756c|M.abscessus_ATCC_199 PMELDIKEAAENGMGPHGLCIGATGSGKSEFLRTLTLGMIATHSPDALNL
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 LLVDFKGGATFLDYANAPHVAAVITNLADDAPLVARMRAALAGEMNRRQE
MUL_0860|M.ulcerans_Agy99 LLIDFKGGATFLDLEKAPHVAAVITNLADQAPLVARMGEALAGEMNRRQH
MAB_3756c|M.abscessus_ATCC_199 VLVDFKGGATFLGLDRAQHVAAIITNLAEEANLVSRMKDALAGEMNRRQE
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 ALRTAG-CDSVAAYQHARRSAAALPALPTLFVIVDEFSELLSQQPDFADT
MUL_0860|M.ulcerans_Agy99 LLRTAGNFVSVAAYEDARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEV
MAB_3756c|M.abscessus_ATCC_199 LLRAAGNFANVTEYERARAAGASLSPLPALFIIVDEFSELLSQHPDFAEL
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 FVAIGRLGRSLGIHLLLASQRLDEGRLRGLDAHLSYRLCLKTLSEAESRA
MUL_0860|M.ulcerans_Agy99 FVAIGRLGRSLGMHLLLASQRLEEGRLRGLEAHLSYRVCLKTLSAIESRT
MAB_3756c|M.abscessus_ATCC_199 FVAIGRLGRSLHVHLLLASQRLDEGRLRGLESHLSYRLCLKTFSANESRA
Rv3871|M.tuberculosis_H37Rv --------------------------------------------------
Mb3901|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5446|M.marinum_M --------------------------------------------------
MLBr_00052|M.leprae_Br4923 --------------------------------------------------
MSMEG_0062|M.smegmatis_MC2_155 --------------------------------------------------
TH_2902|M.thermoresistible__bu --------------------------------------------------
Mflv_0770|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0075|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4390|M.avium_104 VLGNLDAYHLPTDPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP----
MUL_0860|M.ulcerans_Agy99 ALGTLDAFELPNTPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL
MAB_3756c|M.abscessus_ATCC_199 AIGVPDAYHLPNTPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSS
Rv3871|M.tuberculosis_H37Rv ------------------------------MTAEPEVRTLREVVLDQLGT
Mb3901|M.bovis_AF2122/97 ------------------------------MTAEPEVRTLREVVLDQLGT
MMAR_5446|M.marinum_M ------------------------------MTAEPEVRTLREVILDQLST
MLBr_00052|M.leprae_Br4923 ------------------------------MTAEPEVRALREVVLEQLGT
MSMEG_0062|M.smegmatis_MC2_155 ------------------------------MSTEAEPRVLREVVLSQLAT
TH_2902|M.thermoresistible__bu -------------------VRTDSRGDGELMSVTSNQRVLREVVLDQLST
Mflv_0770|M.gilvum_PYR-GCK ------------------------------MTIDSGQKVLREVVLEQLAT
Mvan_0075|M.vanbaalenii_PYR-1 ------------------------------MSIDSGQKVLREVVLEQLTT
MAV_4390|M.avium_104 ---PAMVRVFGTRVVG------PVSR--PVEAAHPSGRSISAAVLDRLAG
MUL_0860|M.ulcerans_Agy99 ---PAAVRPFTSEATG------DVRTGGADGADTATGPTVLQTVLDRIAG
MAB_3756c|M.abscessus_ATCC_199 GGGGAAPRLFTAAPVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEG
. : .:*.::
Rv3871|M.tuberculosis_H37Rv AESRAYKMWLPPLTNPVPLNELIARD------RRQPLRFALGIMDEPRRH
Mb3901|M.bovis_AF2122/97 AESRAYKMWLPPLTNPVPLNELIARD------RRQPLRFALGIMDEPRRH
MMAR_5446|M.marinum_M VESRAYKMWLPPLVDPTPLDELVARD------RRQPLRFALGIMDEPRRH
MLBr_00052|M.leprae_Br4923 GESLAYKMWLPPLLDPLPLNELIERDS-----NRHPLHFALGIMDEPRRH
MSMEG_0062|M.smegmatis_MC2_155 GESRAYKMWLPPLTDPTPVNELVERDY-----QRRPLRFGLGIMDEPRRH
TH_2902|M.thermoresistible__bu GENRAYRMWLPPLAEPTPVDELIARDP-----NRRPLWFGLGVMDEPRRH
Mflv_0770|M.gilvum_PYR-GCK ADNHAYRMWLPPLADPTPVNELVTRDY-----DRRPLRVGLGIMDEPRRH
Mvan_0075|M.vanbaalenii_PYR-1 GENHAYRMWLPPLADPTPVNELIARDY-----DRRPLRIGLGIMDEPRRH
MAV_4390|M.avium_104 HGPAAHRVWLPPLGRPPELRTLLGG--------AADLTVPVGLVDRPFEQ
MUL_0860|M.ulcerans_Agy99 HGPRAHQVWLPPLDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQ
MAB_3756c|M.abscessus_ATCC_199 HGNPAHEVWLPPLDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQ
*:.:***** . : *: * . :*::*.* :
Rv3871|M.tuberculosis_H37Rv LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYC
Mb3901|M.bovis_AF2122/97 LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYC
MMAR_5446|M.marinum_M LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTLVMSAAATHSPRKVQFYC
MLBr_00052|M.leprae_Br4923 RQDIWGVDLSGAGGNIGIGGAPQTGKTTLLQTMVMSAAATHSPRDVQFYC
MSMEG_0062|M.smegmatis_MC2_155 RQEVWGVDVSAAGGNIAVGGAPQTGKSTFLQTLVVSAAATHTPRQVQFYC
TH_2902|M.thermoresistible__bu RQEVWGIDVSGAGGNIAIGGAPQTGKSTFLQTMILSASATHTPRQVQFYC
Mflv_0770|M.gilvum_PYR-GCK RQEVWGVDLTTAAGNIAIGGAPQTGKSTLLQTLILSAAASHTPRQIQFYC
Mvan_0075|M.vanbaalenii_PYR-1 RQEVWGVDVATAAGNIAVGGAPQTGKSTLLQTFILSASASHTPRQIQFYC
MAV_4390|M.avium_104 CRTPLIVDLSGAAGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYC
MUL_0860|M.ulcerans_Agy99 SRTPLTIDLTAAAGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYC
MAB_3756c|M.abscessus_ATCC_199 RRDPYIVDLSAAAGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYC
: :*:: *.**:.: ***::**: : *:: : :.:* * :****
Rv3871|M.tuberculosis_H37Rv IDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEH
Mb3901|M.bovis_AF2122/97 IDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEH
MMAR_5446|M.marinum_M IDLGGGGLIYLENLPHVGGVAGRSEPDKVHRVVAEMQAVMRQREATFKEH
MLBr_00052|M.leprae_Br4923 IDLGGGGLIYLENLPHVGGVANRSEPDRINRVIAEAQAVMRQREITFKEN
MSMEG_0062|M.smegmatis_MC2_155 VDLGGGGLMYLEDLPHVGGVATRAEPDRVNRVVAEVKAVLRAREQVFKQY
TH_2902|M.thermoresistible__bu VDLGGGGLMYLEDLPHVGGVATRSEPDRVNRVIAEVKAVLRQREAIFKQL
Mflv_0770|M.gilvum_PYR-GCK VDMGGGGLIYVEDLPHVGGVATRAEPDRVNRVVAEVKAVLRQREQTFKQY
Mvan_0075|M.vanbaalenii_PYR-1 VDMGGGGLMYIEDLPHVGGVATRAEPDRVNRVVAEVKAVLRQREQTFKEY
MAV_4390|M.avium_104 LDFGGGALSSLHTLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEH
MUL_0860|M.ulcerans_Agy99 LDFGGGALAAVRDLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQ
MAB_3756c|M.abscessus_ATCC_199 LDFGGGTLTSLAQLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAY
:*:*** * : *****.** * *. : .** : : ** *
Rv3871|M.tuberculosis_H37Rv RVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQD
Mb3901|M.bovis_AF2122/97 RVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQD
MMAR_5446|M.marinum_M RVGSIAMYRQLRDDPNQAVASDPYGDVFLIIDGWPAFVSEFPDLEGQVQD
MLBr_00052|M.leprae_Br4923 RVGSMAAYRQLRTNRSHPVAADPFGDVFLIIDGWSAFTSEFPDLEAAVQD
MSMEG_0062|M.smegmatis_MC2_155 RVGSIASYREMRDDPNNPASQDPFGDVFLVIDGWPAFVAEFPDLEPAVQD
TH_2902|M.thermoresistible__bu RVGSMEQYRQMREDPNNPASKDPFGDLFLVIDGWPAFVSEFPDLEPVVQD
Mflv_0770|M.gilvum_PYR-GCK RVGSVADYRAMREDPSHPASADPFGDVFLVIDGWPAFAAEFDALEAAVQD
Mvan_0075|M.vanbaalenii_PYR-1 RVGSMADYRQMREDPNHPASADPFGDVFLVVDGWPAFTAEFPDLEATVQD
MAV_4390|M.avium_104 AIASIADYRQRR----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIA
MUL_0860|M.ulcerans_Agy99 GIDSIAAYRRLR----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITA
MAB_3756c|M.abscessus_ATCC_199 GIDSMAEYRRRKGAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTA
: *: ** : : .*:*.::***. . :* *: :
Rv3871|M.tuberculosis_H37Rv LAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I
Mb3901|M.bovis_AF2122/97 LAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I
MMAR_5446|M.marinum_M LAAQGLSFGVHTILSTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I
MLBr_00052|M.leprae_Br4923 LAAQGLSFGVHTVITTPRWTELRSRVRDYLGTKIEFRLGDVNDTQIDR-I
MSMEG_0062|M.smegmatis_MC2_155 IAGQGLAYGVHVIITTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I
TH_2902|M.thermoresistible__bu LAGQGLAFGVHTVISTPRWTELKSRVRDYLGTKVEFRLGDVNETQIDR-I
Mflv_0770|M.gilvum_PYR-GCK IAGQGLAYGVHTVISTPRWTELRARIRDYLGTKIEFRLGDVNETQIDR-I
Mvan_0075|M.vanbaalenii_PYR-1 IAGQGLAFGVHTMISTPRWTELRSRVRDYLGTKIEFRLGDVNETQIDR-I
MAV_4390|M.avium_104 LAGQGLSFGVHLVLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRA
MUL_0860|M.ulcerans_Agy99 LAGQGLSYGLHVVVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRG
MAB_3756c|M.abscessus_ATCC_199 LAAQGLGFGVHTVVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKL
:*.***.:*:* ::::.**:.:: ::* :**::*:**** :::.**
Rv3871|M.tuberculosis_H37Rv TREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQ
Mb3901|M.bovis_AF2122/97 TREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQ
MMAR_5446|M.marinum_M TREIPANRPGRAVSMEKHHLMIGVPRLDGVHSADNLVEAITAGVAQIAAQ
MLBr_00052|M.leprae_Br4923 ARDIPANRPGRAISVEKHHLMMGVPRFDGAHSADDLVDAMTAGVAQIAAK
MSMEG_0062|M.smegmatis_MC2_155 TREIPANRPGRAVSLEKHHLMMGVPRLDGVHSADNIVEAISSAVQQIADR
TH_2902|M.thermoresistible__bu TREIPADRPGRAISMEKHHLMMGVPRLDGVHSADDLVTAITAAVERIASR
Mflv_0770|M.gilvum_PYR-GCK TREIPVNRPGRAVSTEKHHLMIGVPRLDGVHSAEGLVPAMTAAVKEIAAR
Mvan_0075|M.vanbaalenii_PYR-1 TREIPVNRPGRAVSTEKHHLMIGVPRLDGVHSAEGLVPAMAAAVKEIAAR
MAV_4390|M.avium_104 AAHVPRDSPGRGLSHDGLHMVIASP-VADVAAG-----------------
MUL_0860|M.ulcerans_Agy99 ARQVPRDRPGRGLCDDGMHMMIALPNVAEVVVSQ--------------QH
MAB_3756c|M.abscessus_ATCC_199 AQLVPDGRPGRGITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQR
: :* . ***.: : *:::. * .
Rv3871|M.tuberculosis_H37Rv HTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAH
Mb3901|M.bovis_AF2122/97 HTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAH
MMAR_5446|M.marinum_M HTDKAPPVRTLPERIHLHELDPNPPGPESDYRTRWEIPIGLRESDMEVAY
MLBr_00052|M.leprae_Br4923 TTEQAPRVRVLPSQVYLQEIDPNPPGPDSDYRTRWTIPVGVRETDLSVAY
MSMEG_0062|M.smegmatis_MC2_155 HTDQAPQVRVLPERIYLHQLDPNPPGPDSDYRTRWQVPLGVRESDLTVAY
TH_2902|M.thermoresistible__bu HTEVAPRVRVLPERIHLNQLDPNPPGPESDYRTRWTIPLGVREADLSVAY
Mflv_0770|M.gilvum_PYR-GCK HTDEAPPVRVLPSRIHLRDLDQSSPGPDADYRTRWTIPIGLREADLTVAH
Mvan_0075|M.vanbaalenii_PYR-1 HTEEAPRVRVLPSRIHLHELDPTPPGPEADYRTRWTIPVGVRESDLTVAH
MAV_4390|M.avium_104 -ESVAPPIPLLPARVDLDAVRRGS-----GDEFAGRPLLGLQERQLQPLA
MUL_0860|M.ulcerans_Agy99 AGSGAPAVPLLPQRVEHRDVVEAA-----GAALSGRILLGLQQRRLQPVA
MAB_3756c|M.abscessus_ATCC_199 SSVEAPQVRMLPHKIDYAALVPQAP---QNDQPNLRILVGINESELAPTF
** : ** :: : . . :*:.: :
Rv3871|M.tuberculosis_H37Rv CHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGL
Mb3901|M.bovis_AF2122/97 CHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGL
MMAR_5446|M.marinum_M SHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPDQVRFMLADYRSGL
MLBr_00052|M.leprae_Br4923 AHMSSNPHLLIFGNSKSGKTRIVHAIARAICARNSPKQVRFMLADYRSSL
MSMEG_0062|M.smegmatis_MC2_155 NQMHLTPHLLIFGAPKSGKTRIAHAVAQAICKRNSPQQVRFMLADYRSGL
TH_2902|M.thermoresistible__bu NQMYITPHQIIFGAPKSGKTRIAHALAQAICARNSPDQVRFMLADFRSGL
Mflv_0770|M.gilvum_PYR-GCK NHMYSTPHQLIFGAPKSGKTTIAHAVARAICARNSPKQVRFMIADYRSGL
Mvan_0075|M.vanbaalenii_PYR-1 NHMHSTPHHLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMVADYRSGL
MAV_4390|M.avium_104 IDFARESHLLILGANGCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRAL
MUL_0860|M.ulcerans_Agy99 VDFEHHAHLLILGDNACGKSSALRTLCREITRTKTAAQARLFLVDFRREL
MAB_3756c|M.abscessus_ATCC_199 LEFGEQPHMMIFGDSECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTL
.: .* :*:* .**: :::.: : .:. *.::.:.*:* *
Rv3871|M.tuberculosis_H37Rv LDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSR
Mb3901|M.bovis_AF2122/97 LDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSR
MMAR_5446|M.marinum_M LDAVPDTHLLSAGAINRNSATLDEAVKALAANLKNRLPPADLTTAQLRSR
MLBr_00052|M.leprae_Br4923 LDAVPDSHLLDAGAINRNSASLDEAIRALTTNLKKRLPPADLTTAQVRSR
MSMEG_0062|M.smegmatis_MC2_155 LDAVPQSHLLDAGAINRNSATLEEAIKALAVNLKKRLPPPDLTTAQLRAR
TH_2902|M.thermoresistible__bu LDAVPESHLLAAGAVNRNNTVLEESIKALAANLKKRLPPPDLTTAQLRSR
Mflv_0770|M.gilvum_PYR-GCK LEAVPETHLLPAGAINRNQGTLEESIKALAIILSKRLPPADLTPSQLRAR
Mvan_0075|M.vanbaalenii_PYR-1 LEAVPESHLLPAGAINRNHATLEESIKALVANLTKRLPPSDLTPSQLRQR
MAV_4390|M.avium_104 LGIVESEQLRGYAMS---PAALTALLPGLLDLLSGRMPPPDASQAQLRAG
MUL_0860|M.ulcerans_Agy99 LGLSESEYLGGHAIA---AGGLGAFLPGLVELLRARMPAPHLSQARLRDR
MAB_3756c|M.abscessus_ATCC_199 LGVVETEHLAKYAMS---SNTLVDEVPALIELLKSRMPGPDVTQQELRDR
* * . * : .* * *:* .. : .:*
Rv3871|M.tuberculosis_H37Rv SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQ
Mb3901|M.bovis_AF2122/97 SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQ
MMAR_5446|M.marinum_M SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAATDIGLHIIVTCQ
MLBr_00052|M.leprae_Br4923 SWWSGFDVVLLVDDWHMIVSAAGSAPPMGPLAPLLPAAPDIGLHILVTCL
MSMEG_0062|M.smegmatis_MC2_155 SWWSGPDVVLLVDDWHMVTAAAGMVSPMAPLGPLLPAAADIGLHVIVTCQ
TH_2902|M.thermoresistible__bu SWWSGPDVVLLVDDWHMIVAASGMMSPMTPLAPLLPASADIGLHIIVTCQ
Mflv_0770|M.gilvum_PYR-GCK SWWDGPDIVLLVDDWHMITAAGGLMPPMTPLGPLLPAAADIGLHLVVTCQ
Mvan_0075|M.vanbaalenii_PYR-1 SWWTGPDVVLLVDDWHMITAAGGMLSPMAPLAPLLPAAADIGLHLVVTCQ
MAV_4390|M.avium_104 SWWSGPDVYVVVDDYDLVASPSG--NLLAPLVEFLPYASELGLHLIIARR
MUL_0860|M.ulcerans_Agy99 SWWSGPGIYLMVDDYDLECTSAS--NPLLALLEYLPYATDLGLHLIVASR
MAB_3756c|M.abscessus_ATCC_199 SWWSGPEIYILVDDYDLVALASG--NPLLPLAEYLPHSKDIGLHVVIARR
*** * : ::***:.: ... : .* ** : ::***::::
Rv3871|M.tuberculosis_H37Rv MSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSS-EFKVKRRPPGQAF
Mb3901|M.bovis_AF2122/97 MSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSS-EFKVKRRPPGQAF
MMAR_5446|M.marinum_M MSQAYKATMDKFVGAAFGSGAPTMFLSGDKQEFPSS-EFKVKRRPPGQAF
MLBr_00052|M.leprae_Br4923 MSQAYKATMDKFVGSAFGAGAPTIFLSGDKQEFPSS-EIKVKRRPPGQAF
MSMEG_0062|M.smegmatis_MC2_155 MSMAHRATMDKFVGAAYGAGSPTLFLSGEKNDFPSR-DIIVKKRPPGQAF
TH_2902|M.thermoresistible__bu MSQAHKATMDKFVGAAFGAGSPTMFLSGEKNDFPSR-DIIVKKRPPGQAF
Mflv_0770|M.gilvum_PYR-GCK MSQASRATMDKFVGTAYGSGSPTMFLSGEKQDFPSR-EIIVKKRPPGQAF
Mvan_0075|M.vanbaalenii_PYR-1 MSQASRAVMDKFVGAAYGAGTPTMFLSGEKQDFPSR-EIIVKKRPPGQAF
MAV_4390|M.avium_104 SGGAERAMFEPLLAGLRDLGCMSLTMS----EAAPFAAAP--PLPPGRGV
MUL_0860|M.ulcerans_Agy99 SGGATRALFEPLLAALRDFGCMALMMSGRCDEGPLFGSGRPMPLPPGRAV
MAB_3756c|M.abscessus_ATCC_199 TSGASRAMFEPMMARMKDLSCIGLQMSGNKDEGVLLGTVRPSEQPPGRGT
. * :* :: ::. . . : :* : ***:.
Rv3871|M.tuberculosis_H37Rv LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSAG
Mb3901|M.bovis_AF2122/97 LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSAG
MMAR_5446|M.marinum_M LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSPG
MLBr_00052|M.leprae_Br4923 MVS-PEAKEVIQAVYVDPPEVDPPKEVFAVPPASS
MSMEG_0062|M.smegmatis_MC2_155 LVG-PDGKEVIQAAYVDPPE----EEVFSPPSEGS
TH_2902|M.thermoresistible__bu LVT-PDAKEVIQAAYVEAPE----EEV--------
Mflv_0770|M.gilvum_PYR-GCK FVT-PDVKEVIQAAYVDPPD----E----------
Mvan_0075|M.vanbaalenii_PYR-1 YVT-PDVKEVIQAAYVDPPE----EEVF-------
MAV_4390|M.avium_104 LTTRAGADELVQVAWSPP-----------------
MUL_0860|M.ulcerans_Agy99 LVTWAGDERLVQVAWTEPG----------------
MAB_3756c|M.abscessus_ATCC_199 LVMRSGGQQLIQVAWSEPQ----------------
. . ..::*. : .