For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TIDSGQKVLREVVLEQLATADNHAYRMWLPPLADPTPVNELVTRDYDRRPLRVGLGIMDEPRRHRQEVWG VDLTTAAGNIAIGGAPQTGKSTLLQTLILSAAASHTPRQIQFYCVDMGGGGLIYVEDLPHVGGVATRAEP DRVNRVVAEVKAVLRQREQTFKQYRVGSVADYRAMREDPSHPASADPFGDVFLVIDGWPAFAAEFDALEA AVQDIAGQGLAYGVHTVISTPRWTELRARIRDYLGTKIEFRLGDVNETQIDRITREIPVNRPGRAVSTEK HHLMIGVPRLDGVHSAEGLVPAMTAAVKEIAARHTDEAPPVRVLPSRIHLRDLDQSSPGPDADYRTRWTI PIGLREADLTVAHNHMYSTPHQLIFGAPKSGKTTIAHAVARAICARNSPKQVRFMIADYRSGLLEAVPET HLLPAGAINRNQGTLEESIKALAIILSKRLPPADLTPSQLRARSWWDGPDIVLLVDDWHMITAAGGLMPP MTPLGPLLPAAADIGLHLVVTCQMSQASRATMDKFVGTAYGSGSPTMFLSGEKQDFPSREIIVKKRPPGQ AFFVTPDVKEVIQAAYVDPPDE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_0770 | - | - | 100% (583) | cell divisionFtsK/SpoIIIE |
M. gilvum PYR-GCK | Mflv_4959 | - | 3e-83 | 34.52% (588) | cell divisionFtsK/SpoIIIE |
M. gilvum PYR-GCK | Mflv_0327 | - | 5e-64 | 31.90% (558) | cell divisionFtsK/SpoIIIE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3901 | - | 0.0 | 73.07% (583) | hypothetical protein Mb3901 |
M. tuberculosis H37Rv | Rv3871 | - | 0.0 | 73.07% (583) | hypothetical protein Rv3871 |
M. leprae Br4923 | MLBr_00052 | - | 0.0 | 70.79% (582) | hypothetical protein MLBr_00052 |
M. abscessus ATCC 19977 | MAB_3756c | - | 1e-113 | 38.01% (584) | putative FtsK/SpoIIIE family protein |
M. marinum M | MMAR_5446 | - | 0.0 | 72.90% (583) | hypothetical protein MMAR_5446 |
M. avium 104 | MAV_4390 | - | 9e-97 | 37.43% (569) | ftsk/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_0062 | - | 0.0 | 79.25% (583) | ftsk/SpoIIIE family protein |
M. thermoresistible (build 8) | TH_2902 | - | 0.0 | 77.87% (583) | PUTATIVE ftsk/spoiiie family protein |
M. ulcerans Agy99 | MUL_0860 | - | 2e-91 | 36.24% (585) | hypothetical protein MUL_0860 |
M. vanbaalenii PYR-1 | Mvan_0075 | - | 0.0 | 88.51% (583) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 MTQADIVVEAPPELPAPESTGLPARLLPVALSVAGIGVMTVVFASG---- MUL_0860|M.ulcerans_Agy99 -MTEDLVVAAPPELAQTTSTGPLLRLVPLAMSIATLIAMAATYVSG---- MAB_3756c|M.abscessus_ATCC_199 MPGGEVNVQPPPEIPRPVPSPIIAKIMPLVMVVAMVGMIAFFVTSGSFGG Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ---GAAARQPAFLAFPATMLVSTVAAALIGRSR-RGGGGLDADRGRYLEY MUL_0860|M.ulcerans_Agy99 ---APSARNPTMLVLPATMSLSLMVMAVSARGR-RRGAGLDQDRVGYLQY MAB_3756c|M.abscessus_ATCC_199 GAGGGMMRSPMFMLFPIMMMVSMVSMVSNSGGKGAKTSEINEDRKDYLRY Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 LNQLGRSVSEIAAAQCASALRDHPDPDTLWTLIGGPRMWRRRPTGPDFCV MUL_0860|M.ulcerans_Agy99 LSELRQRVTEIAAAQRISSNRTHPEPDTVWTLIGGSRMWERRPADADFCR MAB_3756c|M.abscessus_ATCC_199 LEVVRKNVTDTGAAQRKALLWNNPDPSALWTLAGGRRMWERRPGDSDYCH Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 VRVGMGVLPLARRVVAPPVPAEEVRDPVTATALRRFLHTHATVPG-PVTV MUL_0860|M.ulcerans_Agy99 IRIGLGTQPLATRLVAAPLPPPHRSDPVTVSALRRFLEAHARVTDVPIAI MAB_3756c|M.abscessus_ATCC_199 VRVGTGDQRLAAQLVAPEIGPVEELEPVASVALRRFVRTHSLVPELPIAL Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 DLGAGSPVTIDGDAGAARAVLRAVVCQLAVLHAPDRVGIAAVVGDGDRAH MUL_0860|M.ulcerans_Agy99 ALHGAGVVTIGGDPARVRALLRAMVCQMAVLHGPDQLLVAAVVSDRNRPG MAB_3756c|M.abscessus_ATCC_199 NLRGFAAVTIDGSPEVARGMLRAMICQLAMFHGPDQFLVAAVVNRHAAPH Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 WDWLKWLPHNRHPTHDDALGPMRMVYSTAAQAQQALAG--LPVARLVLVA MUL_0860|M.ulcerans_Agy99 WEWLKWLPHNQHPSHHDEVGAERMVYPNITQASAAFDAVALPVMVIVDTD MAB_3756c|M.abscessus_ATCC_199 WDWLKWLPHSQHPSAFDGVGTSRLVYHSLGEVEESLASLITERERFSRTA Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ERAVAPI-----------------------AGATVIAIGAGDD------G MUL_0860|M.ulcerans_Agy99 EHGKQLP-----------------------AGVTVLEVGRGPD------G MAB_3756c|M.abscessus_ATCC_199 QPSPDRPQILIVVDSGTLIGSERLIVDHGIDSVTLVEIGTRVDPLAARRG Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 APVTIRT-------AAGTVSPSRPDRMTAADALTCARRLAGQRV--TAGD MUL_0860|M.ulcerans_Agy99 TQVVVKR-------AGETTTLTRPDELDQVSALVCARLLAPHRCGDRAGG MAB_3756c|M.abscessus_ATCC_199 MQLELTERGLGAKGNVGSEVFAHPDHLTITEAMACARRLAPYRVLTGSGD Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 G-------DGGWPGLVGLADVSGFDPATLWGRQTGRDRLRAPLGVAADGT MUL_0860|M.ulcerans_Agy99 H-------PGDWARMLGIGEIATYHPVSHWHKRNQRERLCVPIGATADGS MAB_3756c|M.abscessus_ATCC_199 EVQIQTEVSTRWSDIVGIGDPGLLNPEVVWRNRVGRDRLRVPIGIAVDGT Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 PVELDIKEPAEHGMGPHGLCVGATGSGKSELLRTIALGMMARNSPDVLNL MUL_0860|M.ulcerans_Agy99 PVLLDIKEPAARGMGPHGLCIGATGSGKSELLRTVALGMMVGNSPEVLNL MAB_3756c|M.abscessus_ATCC_199 PMELDIKEAAENGMGPHGLCIGATGSGKSEFLRTLTLGMIATHSPDALNL Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 LLVDFKGGATFLDYANAPHVAAVITNLADDAPLVARMRAALAGEMNRRQE MUL_0860|M.ulcerans_Agy99 LLIDFKGGATFLDLEKAPHVAAVITNLADQAPLVARMGEALAGEMNRRQH MAB_3756c|M.abscessus_ATCC_199 VLVDFKGGATFLGLDRAQHVAAIITNLAEEANLVSRMKDALAGEMNRRQE Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 ALRTAG-CDSVAAYQHARRSAAALPALPTLFVIVDEFSELLSQQPDFADT MUL_0860|M.ulcerans_Agy99 LLRTAGNFVSVAAYEDARRRGAGLAALPTLFIIVDEFAELLSQHPDFAEV MAB_3756c|M.abscessus_ATCC_199 LLRAAGNFANVTEYERARAAGASLSPLPALFIIVDEFSELLSQHPDFAEL Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 FVAIGRLGRSLGIHLLLASQRLDEGRLRGLDAHLSYRLCLKTLSEAESRA MUL_0860|M.ulcerans_Agy99 FVAIGRLGRSLGMHLLLASQRLEEGRLRGLEAHLSYRVCLKTLSAIESRT MAB_3756c|M.abscessus_ATCC_199 FVAIGRLGRSLHVHLLLASQRLDEGRLRGLESHLSYRLCLKTFSANESRA Mb3901|M.bovis_AF2122/97 -------------------------------------------------- Rv3871|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5446|M.marinum_M -------------------------------------------------- MLBr_00052|M.leprae_Br4923 -------------------------------------------------- Mflv_0770|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_0075|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0062|M.smegmatis_MC2_155 -------------------------------------------------- TH_2902|M.thermoresistible__bu -------------------------------------------------- MAV_4390|M.avium_104 VLGNLDAYHLPTDPGAGYLRVGAGAPIRFQAALVSGPLRPDTAPRP---- MUL_0860|M.ulcerans_Agy99 ALGTLDAFELPNTPGSGLLSSPTAELTRFETAFVSGPVPAGPPDADSVAL MAB_3756c|M.abscessus_ATCC_199 AIGVPDAYHLPNTPGSCYLKDDSGELTRFQTSYVSGPYVPYGPARRTVSS Mb3901|M.bovis_AF2122/97 ------------------------------MTAEPEVRTLREVVLDQLGT Rv3871|M.tuberculosis_H37Rv ------------------------------MTAEPEVRTLREVVLDQLGT MMAR_5446|M.marinum_M ------------------------------MTAEPEVRTLREVILDQLST MLBr_00052|M.leprae_Br4923 ------------------------------MTAEPEVRALREVVLEQLGT Mflv_0770|M.gilvum_PYR-GCK ------------------------------MTIDSGQKVLREVVLEQLAT Mvan_0075|M.vanbaalenii_PYR-1 ------------------------------MSIDSGQKVLREVVLEQLTT MSMEG_0062|M.smegmatis_MC2_155 ------------------------------MSTEAEPRVLREVVLSQLAT TH_2902|M.thermoresistible__bu -------------------VRTDSRGDGELMSVTSNQRVLREVVLDQLST MAV_4390|M.avium_104 ---PAMVRVFGTRVVG------PVSR--PVEAAHPSGRSISAAVLDRLAG MUL_0860|M.ulcerans_Agy99 ---PAAVRPFTSEATG------DVRTGGADGADTATGPTVLQTVLDRIAG MAB_3756c|M.abscessus_ATCC_199 GGGGAAPRLFTAAPVALQMRPAEVVEDDSPAVSEATGRSVIDTILDRVEG . : .:*.:: Mb3901|M.bovis_AF2122/97 AESRAYKMWLPPLTNPVPLNELIARD------RRQPLRFALGIMDEPRRH Rv3871|M.tuberculosis_H37Rv AESRAYKMWLPPLTNPVPLNELIARD------RRQPLRFALGIMDEPRRH MMAR_5446|M.marinum_M VESRAYKMWLPPLVDPTPLDELVARD------RRQPLRFALGIMDEPRRH MLBr_00052|M.leprae_Br4923 GESLAYKMWLPPLLDPLPLNELIERDS-----NRHPLHFALGIMDEPRRH Mflv_0770|M.gilvum_PYR-GCK ADNHAYRMWLPPLADPTPVNELVTRDY-----DRRPLRVGLGIMDEPRRH Mvan_0075|M.vanbaalenii_PYR-1 GENHAYRMWLPPLADPTPVNELIARDY-----DRRPLRIGLGIMDEPRRH MSMEG_0062|M.smegmatis_MC2_155 GESRAYKMWLPPLTDPTPVNELVERDY-----QRRPLRFGLGIMDEPRRH TH_2902|M.thermoresistible__bu GENRAYRMWLPPLAEPTPVDELIARDP-----NRRPLWFGLGVMDEPRRH MAV_4390|M.avium_104 HGPAAHRVWLPPLGRPPELRTLLGG--------AADLTVPVGLVDRPFEQ MUL_0860|M.ulcerans_Agy99 HGPRAHQVWLPPLDRAPALASLLSDGAAE----HAELAVPIGVVDRPFDQ MAB_3756c|M.abscessus_ATCC_199 HGNPAHEVWLPPLDDSPTLGDLIPRHGRAGFDAVGSLTVPIGIVDRPYEQ *:.:***** . : *: * . :*::*.* : Mb3901|M.bovis_AF2122/97 LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYC Rv3871|M.tuberculosis_H37Rv LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYC MMAR_5446|M.marinum_M LQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTLVMSAAATHSPRKVQFYC MLBr_00052|M.leprae_Br4923 RQDIWGVDLSGAGGNIGIGGAPQTGKTTLLQTMVMSAAATHSPRDVQFYC Mflv_0770|M.gilvum_PYR-GCK RQEVWGVDLTTAAGNIAIGGAPQTGKSTLLQTLILSAAASHTPRQIQFYC Mvan_0075|M.vanbaalenii_PYR-1 RQEVWGVDVATAAGNIAVGGAPQTGKSTLLQTFILSASASHTPRQIQFYC MSMEG_0062|M.smegmatis_MC2_155 RQEVWGVDVSAAGGNIAVGGAPQTGKSTFLQTLVVSAAATHTPRQVQFYC TH_2902|M.thermoresistible__bu RQEVWGIDVSGAGGNIAIGGAPQTGKSTFLQTMILSASATHTPRQVQFYC MAV_4390|M.avium_104 CRTPLIVDLSGAAGNVAVVGAPRSGKSTALRTLITALAATHDPARVQFYC MUL_0860|M.ulcerans_Agy99 SRTPLTIDLTAAAGNVAVVGAPQSGKSTTLSTLITALAATHDPDLVQFYC MAB_3756c|M.abscessus_ATCC_199 RRDPYIVDLSAAAGNVAIVGAPQSGKSMAVRTLVTSLAVTHSPAQVQFYC : :*:: *.**:.: ***::**: : *:: : :.:* * :**** Mb3901|M.bovis_AF2122/97 IDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEH Rv3871|M.tuberculosis_H37Rv IDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEH MMAR_5446|M.marinum_M IDLGGGGLIYLENLPHVGGVAGRSEPDKVHRVVAEMQAVMRQREATFKEH MLBr_00052|M.leprae_Br4923 IDLGGGGLIYLENLPHVGGVANRSEPDRINRVIAEAQAVMRQREITFKEN Mflv_0770|M.gilvum_PYR-GCK VDMGGGGLIYVEDLPHVGGVATRAEPDRVNRVVAEVKAVLRQREQTFKQY Mvan_0075|M.vanbaalenii_PYR-1 VDMGGGGLMYIEDLPHVGGVATRAEPDRVNRVVAEVKAVLRQREQTFKEY MSMEG_0062|M.smegmatis_MC2_155 VDLGGGGLMYLEDLPHVGGVATRAEPDRVNRVVAEVKAVLRAREQVFKQY TH_2902|M.thermoresistible__bu VDLGGGGLMYLEDLPHVGGVATRSEPDRVNRVIAEVKAVLRQREAIFKQL MAV_4390|M.avium_104 LDFGGGALSSLHTLPHVGAVAGRAEPRRVGRIVAECEAVVGRREAFFGEH MUL_0860|M.ulcerans_Agy99 LDFGGGALAAVRDLPHVGAVAGRGEPDLIRGIVAELESCLRTRESLFGEQ MAB_3756c|M.abscessus_ATCC_199 LDFGGGTLTSLAQLPHVGSVASRLESDLIRRTFAEMLTIVRSRENAFRAY :*:*** * : *****.** * *. : .** : : ** * Mb3901|M.bovis_AF2122/97 RVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQD Rv3871|M.tuberculosis_H37Rv RVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQD MMAR_5446|M.marinum_M RVGSIAMYRQLRDDPNQAVASDPYGDVFLIIDGWPAFVSEFPDLEGQVQD MLBr_00052|M.leprae_Br4923 RVGSMAAYRQLRTNRSHPVAADPFGDVFLIIDGWSAFTSEFPDLEAAVQD Mflv_0770|M.gilvum_PYR-GCK RVGSVADYRAMREDPSHPASADPFGDVFLVIDGWPAFAAEFDALEAAVQD Mvan_0075|M.vanbaalenii_PYR-1 RVGSMADYRQMREDPNHPASADPFGDVFLVVDGWPAFTAEFPDLEATVQD MSMEG_0062|M.smegmatis_MC2_155 RVGSIASYREMRDDPNNPASQDPFGDVFLVIDGWPAFVAEFPDLEPAVQD TH_2902|M.thermoresistible__bu RVGSMEQYRQMREDPNNPASKDPFGDLFLVIDGWPAFVSEFPDLEPVVQD MAV_4390|M.avium_104 AIASIADYRQRR----PGS--DPFGDVFLVIDGWAVLRRDFETLEASIIA MUL_0860|M.ulcerans_Agy99 GIDSIAAYRRLR----ADSGAQRLADLFVVIDGWATLCHEFEELQEPITA MAB_3756c|M.abscessus_ATCC_199 GIDSMAEYRRRKGAGDPQLANDPFGDVFFIIDGWSTVRQEFEALEPQVTA : *: ** : : .*:*.::***. . :* *: : Mb3901|M.bovis_AF2122/97 LAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I Rv3871|M.tuberculosis_H37Rv LAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I MMAR_5446|M.marinum_M LAAQGLSFGVHTILSTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I MLBr_00052|M.leprae_Br4923 LAAQGLSFGVHTVITTPRWTELRSRVRDYLGTKIEFRLGDVNDTQIDR-I Mflv_0770|M.gilvum_PYR-GCK IAGQGLAYGVHTVISTPRWTELRARIRDYLGTKIEFRLGDVNETQIDR-I Mvan_0075|M.vanbaalenii_PYR-1 IAGQGLAFGVHTMISTPRWTELRSRVRDYLGTKIEFRLGDVNETQIDR-I MSMEG_0062|M.smegmatis_MC2_155 IAGQGLAYGVHVIITTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDR-I TH_2902|M.thermoresistible__bu LAGQGLAFGVHTVISTPRWTELKSRVRDYLGTKVEFRLGDVNETQIDR-I MAV_4390|M.avium_104 LAGQGLSFGVHLVLSASRWADIRPALRDQIGTRIELRLGDPADSEIDRRA MUL_0860|M.ulcerans_Agy99 LAGQGLSYGLHVVVSATRWAHLRGSLKDQLGTRIELRLGDPADSEVDRRG MAB_3756c|M.abscessus_ATCC_199 LAAQGLGFGVHTVVTASRWAEIRPALKDQIGTRVELRLGDPLDSDFDRKL :*.***.:*:* ::::.**:.:: ::* :**::*:**** :::.** Mb3901|M.bovis_AF2122/97 TREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQ Rv3871|M.tuberculosis_H37Rv TREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQ MMAR_5446|M.marinum_M TREIPANRPGRAVSMEKHHLMIGVPRLDGVHSADNLVEAITAGVAQIAAQ MLBr_00052|M.leprae_Br4923 ARDIPANRPGRAISVEKHHLMMGVPRFDGAHSADDLVDAMTAGVAQIAAK Mflv_0770|M.gilvum_PYR-GCK TREIPVNRPGRAVSTEKHHLMIGVPRLDGVHSAEGLVPAMTAAVKEIAAR Mvan_0075|M.vanbaalenii_PYR-1 TREIPVNRPGRAVSTEKHHLMIGVPRLDGVHSAEGLVPAMAAAVKEIAAR MSMEG_0062|M.smegmatis_MC2_155 TREIPANRPGRAVSLEKHHLMMGVPRLDGVHSADNIVEAISSAVQQIADR TH_2902|M.thermoresistible__bu TREIPADRPGRAISMEKHHLMMGVPRLDGVHSADDLVTAITAAVERIASR MAV_4390|M.avium_104 AAHVPRDSPGRGLSHDGLHMVIASP-VADVAAG----------------- MUL_0860|M.ulcerans_Agy99 ARQVPRDRPGRGLCDDGMHMMIALPNVAEVVVSQ--------------QH MAB_3756c|M.abscessus_ATCC_199 AQLVPDGRPGRGITRDRRHMLIGLPRVDSISSNQDLGEAIAAAAASMRQR : :* . ***.: : *:::. * . Mb3901|M.bovis_AF2122/97 HTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAH Rv3871|M.tuberculosis_H37Rv HTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAH MMAR_5446|M.marinum_M HTDKAPPVRTLPERIHLHELDPNPPGPESDYRTRWEIPIGLRESDMEVAY MLBr_00052|M.leprae_Br4923 TTEQAPRVRVLPSQVYLQEIDPNPPGPDSDYRTRWTIPVGVRETDLSVAY Mflv_0770|M.gilvum_PYR-GCK HTDEAPPVRVLPSRIHLRDLDQSSPGPDADYRTRWTIPIGLREADLTVAH Mvan_0075|M.vanbaalenii_PYR-1 HTEEAPRVRVLPSRIHLHELDPTPPGPEADYRTRWTIPVGVRESDLTVAH MSMEG_0062|M.smegmatis_MC2_155 HTDQAPQVRVLPERIYLHQLDPNPPGPDSDYRTRWQVPLGVRESDLTVAY TH_2902|M.thermoresistible__bu HTEVAPRVRVLPERIHLNQLDPNPPGPESDYRTRWTIPLGVREADLSVAY MAV_4390|M.avium_104 -ESVAPPIPLLPARVDLDAVRRGS-----GDEFAGRPLLGLQERQLQPLA MUL_0860|M.ulcerans_Agy99 AGSGAPAVPLLPQRVEHRDVVEAA-----GAALSGRILLGLQQRRLQPVA MAB_3756c|M.abscessus_ATCC_199 SSVEAPQVRMLPHKIDYAALVPQAP---QNDQPNLRILVGINESELAPTF ** : ** :: : . . :*:.: : Mb3901|M.bovis_AF2122/97 CHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGL Rv3871|M.tuberculosis_H37Rv CHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGL MMAR_5446|M.marinum_M SHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPDQVRFMLADYRSGL MLBr_00052|M.leprae_Br4923 AHMSSNPHLLIFGNSKSGKTRIVHAIARAICARNSPKQVRFMLADYRSSL Mflv_0770|M.gilvum_PYR-GCK NHMYSTPHQLIFGAPKSGKTTIAHAVARAICARNSPKQVRFMIADYRSGL Mvan_0075|M.vanbaalenii_PYR-1 NHMHSTPHHLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMVADYRSGL MSMEG_0062|M.smegmatis_MC2_155 NQMHLTPHLLIFGAPKSGKTRIAHAVAQAICKRNSPQQVRFMLADYRSGL TH_2902|M.thermoresistible__bu NQMYITPHQIIFGAPKSGKTRIAHALAQAICARNSPDQVRFMLADFRSGL MAV_4390|M.avium_104 IDFARESHLLILGANGCGKTAALRTLCRELVRTNTAAQAQLVIVDFRRAL MUL_0860|M.ulcerans_Agy99 VDFEHHAHLLILGDNACGKSSALRTLCREITRTKTAAQARLFLVDFRREL MAB_3756c|M.abscessus_ATCC_199 LEFGEQPHMMIFGDSECGKTALLRTMCREIVRTTTPQQAQLFIVDYRRTL .: .* :*:* .**: :::.: : .:. *.::.:.*:* * Mb3901|M.bovis_AF2122/97 LDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSR Rv3871|M.tuberculosis_H37Rv LDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSR MMAR_5446|M.marinum_M LDAVPDTHLLSAGAINRNSATLDEAVKALAANLKNRLPPADLTTAQLRSR MLBr_00052|M.leprae_Br4923 LDAVPDSHLLDAGAINRNSASLDEAIRALTTNLKKRLPPADLTTAQVRSR Mflv_0770|M.gilvum_PYR-GCK LEAVPETHLLPAGAINRNQGTLEESIKALAIILSKRLPPADLTPSQLRAR Mvan_0075|M.vanbaalenii_PYR-1 LEAVPESHLLPAGAINRNHATLEESIKALVANLTKRLPPSDLTPSQLRQR MSMEG_0062|M.smegmatis_MC2_155 LDAVPQSHLLDAGAINRNSATLEEAIKALAVNLKKRLPPPDLTTAQLRAR TH_2902|M.thermoresistible__bu LDAVPESHLLAAGAVNRNNTVLEESIKALAANLKKRLPPPDLTTAQLRSR MAV_4390|M.avium_104 LGIVESEQLRGYAMS---PAALTALLPGLLDLLSGRMPPPDASQAQLRAG MUL_0860|M.ulcerans_Agy99 LGLSESEYLGGHAIA---AGGLGAFLPGLVELLRARMPAPHLSQARLRDR MAB_3756c|M.abscessus_ATCC_199 LGVVETEHLAKYAMS---SNTLVDEVPALIELLKSRMPGPDVTQQELRDR * * . * : .* * *:* .. : .:* Mb3901|M.bovis_AF2122/97 SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQ Rv3871|M.tuberculosis_H37Rv SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQ MMAR_5446|M.marinum_M SWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAATDIGLHIIVTCQ MLBr_00052|M.leprae_Br4923 SWWSGFDVVLLVDDWHMIVSAAGSAPPMGPLAPLLPAAPDIGLHILVTCL Mflv_0770|M.gilvum_PYR-GCK SWWDGPDIVLLVDDWHMITAAGGLMPPMTPLGPLLPAAADIGLHLVVTCQ Mvan_0075|M.vanbaalenii_PYR-1 SWWTGPDVVLLVDDWHMITAAGGMLSPMAPLAPLLPAAADIGLHLVVTCQ MSMEG_0062|M.smegmatis_MC2_155 SWWSGPDVVLLVDDWHMVTAAAGMVSPMAPLGPLLPAAADIGLHVIVTCQ TH_2902|M.thermoresistible__bu SWWSGPDVVLLVDDWHMIVAASGMMSPMTPLAPLLPASADIGLHIIVTCQ MAV_4390|M.avium_104 SWWSGPDVYVVVDDYDLVASPSG--NLLAPLVEFLPYASELGLHLIIARR MUL_0860|M.ulcerans_Agy99 SWWSGPGIYLMVDDYDLECTSAS--NPLLALLEYLPYATDLGLHLIVASR MAB_3756c|M.abscessus_ATCC_199 SWWSGPEIYILVDDYDLVALASG--NPLLPLAEYLPHSKDIGLHVVIARR *** * : ::***:.: ... : .* ** : ::***:::: Mb3901|M.bovis_AF2122/97 MSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSS-EFKVKRRPPGQAF Rv3871|M.tuberculosis_H37Rv MSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSS-EFKVKRRPPGQAF MMAR_5446|M.marinum_M MSQAYKATMDKFVGAAFGSGAPTMFLSGDKQEFPSS-EFKVKRRPPGQAF MLBr_00052|M.leprae_Br4923 MSQAYKATMDKFVGSAFGAGAPTIFLSGDKQEFPSS-EIKVKRRPPGQAF Mflv_0770|M.gilvum_PYR-GCK MSQASRATMDKFVGTAYGSGSPTMFLSGEKQDFPSR-EIIVKKRPPGQAF Mvan_0075|M.vanbaalenii_PYR-1 MSQASRAVMDKFVGAAYGAGTPTMFLSGEKQDFPSR-EIIVKKRPPGQAF MSMEG_0062|M.smegmatis_MC2_155 MSMAHRATMDKFVGAAYGAGSPTLFLSGEKNDFPSR-DIIVKKRPPGQAF TH_2902|M.thermoresistible__bu MSQAHKATMDKFVGAAFGAGSPTMFLSGEKNDFPSR-DIIVKKRPPGQAF MAV_4390|M.avium_104 SGGAERAMFEPLLAGLRDLGCMSLTMS----EAAPFAAAP--PLPPGRGV MUL_0860|M.ulcerans_Agy99 SGGATRALFEPLLAALRDFGCMALMMSGRCDEGPLFGSGRPMPLPPGRAV MAB_3756c|M.abscessus_ATCC_199 TSGASRAMFEPMMARMKDLSCIGLQMSGNKDEGVLLGTVRPSEQPPGRGT . * :* :: ::. . . : :* : ***:. Mb3901|M.bovis_AF2122/97 LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSAG Rv3871|M.tuberculosis_H37Rv LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSAG MMAR_5446|M.marinum_M LVS-PDGKEVIQAPYIEPP-----EEVFAAPPSPG MLBr_00052|M.leprae_Br4923 MVS-PEAKEVIQAVYVDPPEVDPPKEVFAVPPASS Mflv_0770|M.gilvum_PYR-GCK FVT-PDVKEVIQAAYVDPPD----E---------- Mvan_0075|M.vanbaalenii_PYR-1 YVT-PDVKEVIQAAYVDPPE----EEVF------- MSMEG_0062|M.smegmatis_MC2_155 LVG-PDGKEVIQAAYVDPPE----EEVFSPPSEGS TH_2902|M.thermoresistible__bu LVT-PDAKEVIQAAYVEAPE----EEV-------- MAV_4390|M.avium_104 LTTRAGADELVQVAWSPP----------------- MUL_0860|M.ulcerans_Agy99 LVTWAGDERLVQVAWTEPG---------------- MAB_3756c|M.abscessus_ATCC_199 LVMRSGGQQLIQVAWSEPQ---------------- . . ..::*. : .