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M. tuberculosis H37Rv Rv3853 (menG)

annotation: ribonuclease activity regulator protein RraA
coordinates: 4325495 - 4325968
length: 157

VAISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQDNALLKSVLSQPSAGGVLVIDGAG
SLHTALVGDVIAELARSTGWTGLIVHGAVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVT
FVPGDIAYSDDDGIIVV
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3853menG-100% (157)ribonuclease activity regulator protein RraA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3883menG3e-86100.00% (157) ribonuclease activity regulator protein RraA
M. gilvum PYR-GCKMflv_1124-9e-6977.07% (157) ribonuclease activity regulator protein RraA
M. leprae Br4923MLBr_00066menG2e-7586.62% (157) ribonuclease activity regulator protein RraA
M. abscessus ATCC 19977MAB_0107c-4e-5767.10% (155) hypothetical protein MAB_0107c
M. marinum MMMAR_5403menG2e-7990.32% (155) s-adenosylmethionine:2-demethylmenaquinone
M. avium 104MAV_0174-3e-7887.26% (157) ribonuclease activity regulator protein RraA
M. smegmatis MC2 155MSMEG_6439-6e-6675.16% (157) ribonuclease activity regulator protein RraA
M. thermoresistible (build 8)TH_1177menG1e-7080.13% (156) PROBABLE S-ADENOSYLMETHIONINE:2-DEMETHYLMENAQUINONE
M. ulcerans Agy99MUL_5025menG4e-8090.97% (155) ribonuclease activity regulator protein RraA
M. vanbaalenii PYR-1Mvan_5682-8e-6977.71% (157) ribonuclease activity regulator protein RraA

CLUSTAL 2.0.9 multiple sequence alignment


Rv3853|M.tuberculosis_H37Rv         --MA-ISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQD
Mb3883|M.bovis_AF2122/97            --MA-ISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQD
MMAR_5403|M.marinum_M               --MGNVAFRPTADLVDDIGPDVRSCDLQFRQFGGRAEFAGPISTVRCFQD
MUL_5025|M.ulcerans_Agy99           --MGNVAFRPTADLVDDIGPDVRSCDLQFRQFGGHAEFAGPISTVRCFQD
MLBr_00066|M.leprae_Br4923          ---MIVSFRPTADLVDSIGVDVRSCDLQFRQFGGCSEFAGPISTVRCFQD
MAV_0174|M.avium_104                ---MTVSFRPTADLVDDIGPDVRSCDLQFRQLGGRTEFAGPISTVRCFQD
Mflv_1124|M.gilvum_PYR-GCK          ---MAVTPRPTADLVDEIGPEVRSCDLQMRQFGGRSEFAGPITTVRCFED
Mvan_5682|M.vanbaalenii_PYR-1       ---MTVTPRPTADLVDEIGPDVRSCDLQLRQYGGRTDFAGPITTVRCFQD
TH_1177|M.thermoresistible__bu      ---VIVEPRPTADLVDEIGPDVRSCDLQLQQYGGRAQFAGPISTVRCFQD
MSMEG_6439|M.smegmatis_MC2_155      ---MSIEPRATADLVDEIYPDVRSCDLQLQNYGGKIMFAGPVTTVRCFQD
MAB_0107c|M.abscessus_ATCC_199      MTTAPITPRPTADLGDELGIDMASCDLQLNQYGARPVFAGVITTVRCHHD
                                         :  *.**** *.:  :: *****:.: *.   *** ::****..*

Rv3853|M.tuberculosis_H37Rv         NALLKSVLSQPSAGGVLVIDGAGSLHTALVGDVIAELARSTGWTGLIVHG
Mb3883|M.bovis_AF2122/97            NALLKSVLSQPSAGGVLVIDGAGSLHTALVGDVIAELARSTGWTGLIVHG
MMAR_5403|M.marinum_M               NALLKSVLSQPGEGGVLVIDGAGSLHTALVGDVIAELARSNGWAGLVVHG
MUL_5025|M.ulcerans_Agy99           NALLKSVLSQPGEGGVLVIDGAGSLHTALVGDVIAELARSNGWTGLVVHG
MLBr_00066|M.leprae_Br4923          NALLKSVLSQTSAGGVLVVDGAGSLHTALVGDVIAELAHSNGWAGLIVNG
MAV_0174|M.avium_104                NALLKSVLSEPGGGGVLVVDGGGSLHTALVGDVIAELARANGWAGLIVNG
Mflv_1124|M.gilvum_PYR-GCK          NALLKSVLSEPGDGGVLVVDGDGSVHTALVGDVIAELGRSNGWSGLIING
Mvan_5682|M.vanbaalenii_PYR-1       NALLKSVLSEPGDGGVLVIDGDGSVHTALVGDVIAELGRSNGWSGLIING
TH_1177|M.thermoresistible__bu      NALLKSVLSEPGNGGVLVIDGDGSLHTALVGDVIAELARGNGWAGLIING
MSMEG_6439|M.smegmatis_MC2_155      NALLKSILSTPGEGAVLVVDGAGSLHTALVGDVIAGLAADNGWSGVIVNG
MAB_0107c|M.abscessus_ATCC_199      NALLKSVLSEPSSGGVLVIDGGGSLHCALVGDVIAGLAVASGWSGLVING
                                    ******:** .. *.***:** **:* ******** *.  .**:*::::*

Rv3853|M.tuberculosis_H37Rv         AVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVTFVPGDIA
Mb3883|M.bovis_AF2122/97            AVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVTFVPGDIA
MMAR_5403|M.marinum_M               AVRDSAALRGIDIGIKALGTNPRKSTKTGSGERDAEITLGGVTFAPGEIA
MUL_5025|M.ulcerans_Agy99           AVRDSAALRGIDIGIKALGTNPRKSTKTGSGERDAEITLGGVTFVPGEIA
MLBr_00066|M.leprae_Br4923          AVRDAAALRGIDIGIKALGTNPRKSTKIGTGERHVEVNLGGVTFVPGEVV
MAV_0174|M.avium_104                AVRDSAALRGMDIGVKALGTNPRKSTKTGAGERDVDITLGGVTFTPGDIA
Mflv_1124|M.gilvum_PYR-GCK          AVRDASTLRTLDIGIKALGTNPRKSSKTGDGVRDAVVEFGGVVFTPGDIA
Mvan_5682|M.vanbaalenii_PYR-1       AVRDASTLRTLDIGIKALGTNPRKSTKTGEGIRDEAVEFGGVVFTPGDIA
TH_1177|M.thermoresistible__bu      AVRDSATLRTLDIGIKALGTNPRKSTKTGAGQRDVAVEFGGVTFVPGEIA
MSMEG_6439|M.smegmatis_MC2_155      AVRDAAALRTIDVGIKALGTNPRKGTKTGEGERDVEVSFGGVTFTPGDIA
MAB_0107c|M.abscessus_ATCC_199      VVRDSAELATMDIGIKALGTNPRKGHKTGAGERDVVVSFGGIDFTPGAIC
                                    .***:: *  :*:*:*********. * * * *.  : :**: *.** : 

Rv3853|M.tuberculosis_H37Rv         YSDDDGIIVV----------------------------------------
Mb3883|M.bovis_AF2122/97            YSDDDGIIVV----------------------------------------
MMAR_5403|M.marinum_M               YSDDDGIVVVAAVATES---------------------------------
MUL_5025|M.ulcerans_Agy99           YSDDDGIVVVAAVATES---------------------------------
MLBr_00066|M.leprae_Br4923          YSDDDGIVVV----------------------------------------
MAV_0174|M.avium_104                YSDDDGIVVVAAGD------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          YSDDDGIVVVTAD-------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       YSDDDGIVVIAAG-------------------------------------
TH_1177|M.thermoresistible__bu      YADEDGIVVXXGGNGGRGGSVILVVDPQVHTLLDFHFHPHVVAPSGKPGQ
MSMEG_6439|M.smegmatis_MC2_155      YCDEDGIVVVTP--------------------------------------
MAB_0107c|M.abscessus_ATCC_199      YADHDGVVVVPA--------------------------------------
                                    *.*.**::*                                         

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      GSNRDGAAGADLEVKVPDGTVVLDEHGNLLADLTGAGTRFVAAEGGRGGL
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      GNAALASRARKAPGFALLGEPGQARDLVLELKTVADVGLIGYPSAGKSSL
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      VSTISAAKPKIADYPFTTLTPNLGVVSAGDETFTVADVPGLIPGASEGRG
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      LGLDFLRHIERCAVLVHVVDCATLELGRDPVSDIETLENELAAYTPTLQG
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      DSELDDLTERPRAVVLNKIDVPEARELAEFVRDEIVQRFGWPVFLVSTAT
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      REGLRPLVFALWEMMKQYRASQPEVAPRRPVIRPVPVDETGFTVHPDGEG
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      GFVVRGVRPERWVTQTDFNNDEAVGYLADRLARLGVEEELLQLGAEPGCE
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3883|M.bovis_AF2122/97            --------------------------------------------------
MMAR_5403|M.marinum_M               --------------------------------------------------
MUL_5025|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00066|M.leprae_Br4923          --------------------------------------------------
MAV_0174|M.avium_104                --------------------------------------------------
Mflv_1124|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5682|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_1177|M.thermoresistible__bu      VTIGDMTFEWEPQTPAGVDDVPLSGRGTDARLEQSERVTAAERKAARRAR
MSMEG_6439|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0107c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Rv3853|M.tuberculosis_H37Rv         -------
Mb3883|M.bovis_AF2122/97            -------
MMAR_5403|M.marinum_M               -------
MUL_5025|M.ulcerans_Agy99           -------
MLBr_00066|M.leprae_Br4923          -------
MAV_0174|M.avium_104                -------
Mflv_1124|M.gilvum_PYR-GCK          -------
Mvan_5682|M.vanbaalenii_PYR-1       -------
TH_1177|M.thermoresistible__bu      REPGGEP
MSMEG_6439|M.smegmatis_MC2_155      -------
MAB_0107c|M.abscessus_ATCC_199      -------