For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv3795 (embB)

annotation: INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBB (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE)
coordinates: 4246514 - 4249810
length: 1098

MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPVVQTTAMLDWPQRGQLGSVTAP
LISLTPVDFTATVPCDVVRAMPPAGGVVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQV
TSPQCQRIEVTSTHAGTFANFVGLKDPSGAPLRSGFPDPNLRPQIVGVFTDLTGPAPPGLAVSATIDTRF
STRPTTLKLLAIIGAIVATVVALIALWRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTD
AVVIFGFLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNLLALMTHVSDASLWM
RLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWAAAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIE
RSMRYSRLTPAALAVVTAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAGTVIL
TVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVFIMLRR
KRIPSVARGPAWRLMGVIFGTMFFLMFTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLA
ALFFLLALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWLHFAPRGAGEGRLIR
ALTTAPVPIVAGFMAAVFVASMVAGIVRQYPTYSNGWSNVRAFVGGCGLADDVLVEPDTNAGFMKPLDGD
SGSWGPLGPLGGVNPVGFTPNGVPEHTVAEAIVMKPNQPGTDYDWDAPTKLTSPGINGSTVPLPYGLDPA
RVPLAGTYTTGAQQQSTLVSAWYLLPKPDDGHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGPGAL
VPAGRMVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTPPRVPDLRSLQEYVGS
TQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRITPDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMA
TYLSRDWARDWGSLRKFDTLVDAPPAQLELGTATRSGLWSPGKIRIGP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3795embB-100% (1098)INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBB (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE)
M. tuberculosis H37RvRv3793embC0.043.58% (1122) integral membrane indolylacetylinositol arabinosyltransferase
M. tuberculosis H37RvRv3794embA0.042.34% (1110) integral membrane indolylacetylinositol arabinosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3824embB0.099.82% (1098) integral membrane indolylacetylinositol arabinosyltransferase
M. gilvum PYR-GCKMflv_1173-0.069.47% (1081) cell wall arabinan synthesis protein
M. leprae Br4923MLBr_00104embB0.078.68% (1088) putative arabinosyl transferase
M. abscessus ATCC 19977MAB_0185c-0.067.01% (1076) arabinosyltransferase B
M. marinum MMMAR_5357embB0.088.56% (1075) integral membrane indolylacetylinositol arabinosyltransferase
M. avium 104MAV_0229-0.044.80% (1087) arabinosyltransferase A
M. smegmatis MC2 155MSMEG_6389-0.068.47% (1091) arabinosyltransferase A
M. thermoresistible (build 8)TH_2242embB0.073.48% (1086) INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE
M. ulcerans Agy99MUL_4974embB0.087.53% (1075) integral membrane indolylacetylinositol arabinosyltransferase
M. vanbaalenii PYR-1Mvan_5632-0.069.64% (1077) cell wall arabinan synthesis protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv3795|M.tuberculosis_H37Rv         -MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPV
Mb3824|M.bovis_AF2122/97            -MTQCASRRKSTPSRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPV
MMAR_5357|M.marinum_M               ---MSVTNETEQDTAATTASAREVRVTRWVATIAGLIGFVLSVATPLLPV
MUL_4974|M.ulcerans_Agy99           ---MSVTNETEQATAATTASAREVRVTRWVATIAGLIGFVLSVATPLLPL
MLBr_00104|M.leprae_Br4923          ---MSVIYRAHRVAIANRTASRNVRVARWVAAIAGLIGFVSSVVTPLLPV
Mflv_1173|M.gilvum_PYR-GCK          ---MRDAAVK-----------DHVRIARWVATIAGLLGFVMAVAVPLLPV
Mvan_5632|M.vanbaalenii_PYR-1       MSGTSGEAVSGTSAGAVNIDARDVKIARWVATIAGLLGFVLAVSIPLLPV
MSMEG_6389|M.smegmatis_MC2_155      MSGNMDEAVSGNMDEAVSAG-KDVRIARWVATIAGLLGFVLSVSIPLLPV
TH_2242|M.thermoresistible__bu      MS-------------------KNVRTTRWVAIITGLLGFLLAVATPLLPV
MAB_0185c|M.abscessus_ATCC_199      --------MTENSVTDTAAEARKLNIARWTATVFGLLGFVLSVSIPLLPV
MAV_0229|M.avium_104                --------------------------------------MLLAVATPLLPV
                                                                          :: :*  ****:

Rv3795|M.tuberculosis_H37Rv         VQTTAMLDWPQRGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGG---
Mb3824|M.bovis_AF2122/97            VQTTAMLDWPQRGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGG---
MMAR_5357|M.marinum_M               VQTTAMLNWPQNGQLNSVTAPLISLTPVNLTASVPCSVVRDMPAKGG---
MUL_4974|M.ulcerans_Agy99           VQTTAMLNWPQNGQLNSVTAPLISLTPVNLTASMPCSVVRDMPAKGG---
MLBr_00104|M.leprae_Br4923          VQTTATLNWPQNGQLNSVTAPLISLTPVDITATVPCAVVAALPPSGG---
Mflv_1173|M.gilvum_PYR-GCK          TQTTATLNWPQGGQFSNVTAPLISQAPVSLTATVPCDVLRDMPADGG---
Mvan_5632|M.vanbaalenii_PYR-1       TQTTATLNWPQQNRLDNVTAPLISQAPVSLTATVPCEVVRSMPADGG---
MSMEG_6389|M.smegmatis_MC2_155      TQTTATLNWPQQGRLDNVTAPLISQAPLELTATVPCSVVRDLPPEGG---
TH_2242|M.thermoresistible__bu      TQTTATLNWPQDGRLANVTAPLISQAPVEMSVTVPCDLIAAMPADGG---
MAB_0185c|M.abscessus_ATCC_199      KVSTATLDWPQQGRLNNVTAPLISQTPMDMTVIVPCAVVNSAPADGA---
MAV_0229|M.avium_104                DQTTAQLNWPQNGSFGSVEAPLIGYVATDLNITVPCQAAAGLAGRGNPGK
                                      :** *:*** . : .* ****. .. .:.  :**      .  *    

Rv3795|M.tuberculosis_H37Rv         -VVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVT----
Mb3824|M.bovis_AF2122/97            -VVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVT----
MMAR_5357|M.marinum_M               -VVLGTAPKQGKDANLQALFVVVNSKRVNVTDRNVVILSVPREQVD----
MUL_4974|M.ulcerans_Agy99           -VVLGTAPKQGKDANLQALFVVVNSKRVNVTDRNVVILSVPREQVD----
MLBr_00104|M.leprae_Br4923          -VVLGTAPKQGKDANLNALFIDVNSQRVDVTDRNVVILSVPRNQVAGDAG
Mflv_1173|M.gilvum_PYR-GCK          -LVFGTAPAEGRDAALNAMLVNVTEERVDVIVRNVVVASVERERIDR---
Mvan_5632|M.vanbaalenii_PYR-1       -LLLGTAPAEGRDAALNAMLVTVSDDRVDVIVRNVVVASVDRDRVA----
MSMEG_6389|M.smegmatis_MC2_155      -LVFGTAPAEGRDAALNAMLVNVTETRVDVIVRNVVVASVNRDRVA----
TH_2242|M.thermoresistible__bu      -MVLGTAPKEGKEAALQGLFVNVTDDRVDITDRNVVIASVERDRVTGAAG
MAB_0185c|M.abscessus_ATCC_199      -VILGTAPPEGKEAALQSLFVRVTKERLDITDRNVVIASVPRTKVA----
MAV_0229|M.avium_104                TVLLSTVPKQAPKAVDRGLLIVRANDDLVLVVRNVPVVTAPLSQVLG---
                                     :::.*.* :. .*  ..:::      : :  *** : :.   ::     

Rv3795|M.tuberculosis_H37Rv         SPQCQRIEVTSTHAGTFANFVGLK-----DPSGAPLRSGFPDPNLRPQIV
Mb3824|M.bovis_AF2122/97            SPQCQRIEVTSTHAGTFANFVGLK-----DPSGAPLRSGFPDPNLRPQIV
MMAR_5357|M.marinum_M               SPQCERIEISSTHAGTFATFVGLK-----DPSGAPLRSGYPDPNLRPQIV
MUL_4974|M.ulcerans_Agy99           SPQCERIEISSTHAGTFATFVGVK-----DPSGAPLRSGYPDPNLRPQIV
MLBr_00104|M.leprae_Br4923          APGCSSIEVTSTHAGTFATFVGVT-----DSAGNPLRGGFPDPNLRPQIV
Mflv_1173|M.gilvum_PYR-GCK          GAGCERLDITSNLDGTYAEFVGLTQE-SGANAGQPQRTGYPDPNLRPAIV
Mvan_5632|M.vanbaalenii_PYR-1       GPGCERIDITSNLDGTFAEFVGLTQV-SGDNAGQPQRTGYPDPNLRPAIV
MSMEG_6389|M.smegmatis_MC2_155      GPDCQRIEITSNLDGTYADFVGLTQI-SGEDAGKLQRTGYPDPNLRPAIV
TH_2242|M.thermoresistible__bu      TPGCSRIEITSSIDGTWATFVGLTGD-DGAD-GEDLRSGFADPNLRPQIV
MAB_0185c|M.abscessus_ATCC_199      SPDCRRIVITSSDKGTFATFEGLHG--DGAEKSADLRSGFPDPNLRPQIV
MAV_0229|M.avium_104                -PACQRLTFTAHADKVTAEFVGLTQGPNTEHPGAPLRGEKSGYDFRPQIV
                                     . *  : .::    . * * *:         .   *   .. ::** **

Rv3795|M.tuberculosis_H37Rv         GVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIAL
Mb3824|M.bovis_AF2122/97            GVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIAL
MMAR_5357|M.marinum_M               GVFTDLTGPAPDGLRLSATIDTRFSTTPTTLKLLAIIGAILATTVALIAL
MUL_4974|M.ulcerans_Agy99           GVFTDLTGPAPDGLRLSATIDTRFSTTPTTLKLLAIIGAILATTVALIAL
MLBr_00104|M.leprae_Br4923          GVFTDLTGGAPSGLRLSATIDTRFSSTPTTLKRFAMMLAIITTVGALVAL
Mflv_1173|M.gilvum_PYR-GCK          GVFTDLTGPAPPGLSFSADIDTRFTTHPTALKLAAIVLAIVCTVIALLAL
Mvan_5632|M.vanbaalenii_PYR-1       GVFTDLTGPAPPGLSFSATIDTRYTTHPTALKLAAILLAIVSTVIALLAL
MSMEG_6389|M.smegmatis_MC2_155      GVFTDLTGPAPQGLSVSAEIDTRFTTHPTALKLAAMLLAIVSTVIALLAL
TH_2242|M.thermoresistible__bu      GVFTDLTGPAPPGLSLSATIDTRFTTTPTPLKLAAILLAIASTVLSVLAL
MAB_0185c|M.abscessus_ATCC_199      GVFTQLSGPAPQGLSLTAHIDTRFSSSPTLLKLAAMVGAVISTIIAVLAL
MAV_0229|M.avium_104                GVFTDLSGPAPPGLSFSATIDTRYSSSPTPLKMAAMILGLVLTGAALVAL
                                    ****:*:* ** ** .:* ****::: ** **  *:: .:  *  :::**

Rv3795|M.tuberculosis_H37Rv         WRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFG
Mb3824|M.bovis_AF2122/97            WRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFG
MMAR_5357|M.marinum_M               WRLDRLDGRR------------------LRSLFPANWRTFTLVDAAVIFG
MUL_4974|M.ulcerans_Agy99           WRLDRLDGRR------------------LRSLFPANWRTFTLVDAAMIFG
MLBr_00104|M.leprae_Br4923          WRLDQLDGRR------------------MRRLIPARWSMFTLVDVAVIFG
Mflv_1173|M.gilvum_PYR-GCK          WRLDRLDGRR------------------MHRIIPTRWRNLTAVDVVVLGT
Mvan_5632|M.vanbaalenii_PYR-1       WRLDRLDGRR------------------MHRVIPTRWRTLTAVDGVVVGG
MSMEG_6389|M.smegmatis_MC2_155      WRLDRLDGRR------------------MHRLIPTRWRTVTAVDGVVVGG
TH_2242|M.thermoresistible__bu      WQLDRLDGRR------------------MQRWIPERWRTFTLADGTVVSA
MAB_0185c|M.abscessus_ATCC_199      WRIDQTDGHR------------------MRRLIPTRWRRFDLTDTVIMSA
MAV_0229|M.avium_104                HILDTADGTR------------------HRRFLPARWWSIGGLDALVIAV
                                      :*  **                     :  :*  *  .   *  ::  

Rv3795|M.tuberculosis_H37Rv         FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
Mb3824|M.bovis_AF2122/97            FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
MMAR_5357|M.marinum_M               FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
MUL_4974|M.ulcerans_Agy99           FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
MLBr_00104|M.leprae_Br4923          FLLWHVIGANSSDDGYQMQMARTADHSGYMANYFRWFGSPEDPFGWYYNL
Mflv_1173|M.gilvum_PYR-GCK          FAIWYVIGANSSDDGYILQMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
Mvan_5632|M.vanbaalenii_PYR-1       FALWYVIGANSSDDGYILQMARVADHAGYMSNYFRWFGSPEDPFGWYYNL
MSMEG_6389|M.smegmatis_MC2_155      MAIWYVIGANSSDDGYILQMARTAEHAGYMANYFRWFGSPEDPFGWYYNV
TH_2242|M.thermoresistible__bu      FVLWHVIGANSSDDGYILGMARVAEHAGYMSNYFRWFGSPEDPFGWYYNL
MAB_0185c|M.abscessus_ATCC_199      LVLWYVIGAGSSDDGYQMGMARTAEHAGYMANYFRWFGSPEDPFGWYYNL
MAV_0229|M.avium_104                LTWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDL
                                    :  *:.:**.:***** : ***.::*:***:**:****:** ******::

Rv3795|M.tuberculosis_H37Rv         LALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWA
Mb3824|M.bovis_AF2122/97            LALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWA
MMAR_5357|M.marinum_M               LALMTHVSDASIWMRLPDLFAGLVCWLLLSREVLPRLGPAVAASKPANWA
MUL_4974|M.ulcerans_Agy99           LALMTHVSDASIWMRLPDLFAGLVCWLLLSREVLPRLGPAVAASKPANWA
MLBr_00104|M.leprae_Br4923          LALMIHVSDASMWIRLPDLICGVACWLLLSREVLPRLGPAIVGFKPALWA
Mflv_1173|M.gilvum_PYR-GCK          LALMTQVSTASIWMRLPDLICSVICWLLLSREVLPRLGPAVIASRPALWA
Mvan_5632|M.vanbaalenii_PYR-1       LALMTQVSTASIWMRLPDLVCALVCWLLLSREVLPRLGPAVSGSRAALWA
MSMEG_6389|M.smegmatis_MC2_155      LALMTKVSDASIWIRLPDLICALICWLLLSREVLPRLGPAVAGSRAAMWA
TH_2242|M.thermoresistible__bu      LALMTQVSTASIWIRLPDLVCGLICWLLLSREVLPRLGPAVVASRPALWA
MAB_0185c|M.abscessus_ATCC_199      LAIMTKFSDISLWIRLPDLIASLVCWLLISREVLPRLGPAVARSKPAAWA
MAV_0229|M.avium_104                LALWAHVSTTSIWMRLPTLAMALTCWWVISREVMPRLGHAVKQNRAAAWT
                                    **:  :.*  *:*:*** *  .: ** ::****:**** *:   :.* *:

Rv3795|M.tuberculosis_H37Rv         AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVV
Mb3824|M.bovis_AF2122/97            AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVV
MMAR_5357|M.marinum_M               AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYGRLTPAALAII
MUL_4974|M.ulcerans_Agy99           AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYGRLTPAALAII
MLBr_00104|M.leprae_Br4923          AGLVLLAAWMPFNNGLRPEGQIALGALITYVLIERAITYGRMTPVALATL
Mflv_1173|M.gilvum_PYR-GCK          AGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT
Mvan_5632|M.vanbaalenii_PYR-1       AGLVLLAAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT
MSMEG_6389|M.smegmatis_MC2_155      AGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT
TH_2242|M.thermoresistible__bu      AALVLLAAWMPFNNGLRPEGQIATGALITYVLIERAIISGRLTPFALAIV
MAB_0185c|M.abscessus_ATCC_199      AGFVLLASWFPFNNGLRPEGQIAVGSLITWVLIERAITSRRLTPAALATI
MAV_0229|M.avium_104                AAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAVACI
                                    *. ::*  *:*::******  ** * *:*:  :**::   *: * *:*  

Rv3795|M.tuberculosis_H37Rv         TAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAG
Mb3824|M.bovis_AF2122/97            TAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAG
MMAR_5357|M.marinum_M               SAAFTLGVQPTGLIAVAALVAGGRPILRILVKRRRQVGTLPLLSPMLAAG
MUL_4974|M.ulcerans_Agy99           SAAFTLGVQPTGLIAVAALVAGGRPILRILVKRRRQVGALPLLSPMLAAG
MLBr_00104|M.leprae_Br4923          TAAFTIGIQPTGLIAVAALLAGGRPMLYILVRRHRAVGAWPLVAPLLAAG
Mflv_1173|M.gilvum_PYR-GCK          TAAFTLGIQPTGLIAVAALVAGGRPILRILMRRRQTVGLWPLLAPMLAAG
Mvan_5632|M.vanbaalenii_PYR-1       TAAFTLGIQPTGLIAVAALVAGGRPILRILMRRRQLVGLWPLLAPLLAAG
MSMEG_6389|M.smegmatis_MC2_155      TAAFTLGIQPTGLIAVAALLAGGRPILRIVMRRRRLVGTWPLIAPLLAAG
TH_2242|M.thermoresistible__bu      TAAFTLGIQPTGLIAVAALIAGGRPILRIVMRRRRLVGTWPLVAPLLAAG
MAB_0185c|M.abscessus_ATCC_199      TAAFTLGIQPTGLIAVAALLAGGRPILRIIVTKHRQVGTWPLVAPMLAAG
MAV_0229|M.avium_104                IGALTLFSGPTGIASIGALLVAIGPLRTILHRRITRFGALPLIAPLLAAA
                                     .*:*:   ***: ::.**:..  *:  *:  :   .*  **::*:***.

Rv3795|M.tuberculosis_H37Rv         TVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGS
Mb3824|M.bovis_AF2122/97            TVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGS
MMAR_5357|M.marinum_M               TIILTVVFADQTLSTVFEATRVRGKIGPSQAWYTENLRYYYLILPTVDGS
MUL_4974|M.ulcerans_Agy99           TIILTVVFADQNLSTMFEATRVRGKIGPSQAWYTENLRYYYLILPTVDGS
MLBr_00104|M.leprae_Br4923          TVVLTVVFAEQTLSTVLEATKVRTAIGPAQAWYTENLRYYYLILPTVDGS
Mflv_1173|M.gilvum_PYR-GCK          TVILAVVFADQTMATVLEATKIRTAIGPSQEWWTENLRYYYLILPTVDGA
Mvan_5632|M.vanbaalenii_PYR-1       TVVLAVVFADQTLATVLEATKIRTAIGPSQEWWTENLRYYYLVLPTTDGA
MSMEG_6389|M.smegmatis_MC2_155      TVILAVVFADQTIATVLEATRIRTAIGPSQEWWTENLRYYYLILPTTDGA
TH_2242|M.thermoresistible__bu      TVVLTVVFADQTLATVLEATRIRTDIGPSQEWYTENLRYYYLILPTVDGS
MAB_0185c|M.abscessus_ATCC_199      TVILPVVFSDQTLATVFEATRIRTAIGPSQAWYTDNLRYYYMFLPTVDGS
MAV_0229|M.avium_104                TVTAILIFRDQTLAGEVQASMLKRAVGPSLSWFDEHIRYERLFMASPDGS
                                    *:   ::* :*.::  .:*: ::  :**:  *: :::**  :.:.: **:

Rv3795|M.tuberculosis_H37Rv         LSRRFGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLM
Mb3824|M.bovis_AF2122/97            LSRRFGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLM
MMAR_5357|M.marinum_M               LSRRFGFLITALCLFTAVFIMLRRKRVAGVARGPAWRLMGVIFGTMFFLM
MUL_4974|M.ulcerans_Agy99           LSRRFGFLITALCLFTAVFIMLRRKRVAGVARGPAWRLMGVIFGTMFFLM
MLBr_00104|M.leprae_Br4923          LSRRFGFLITALCLFTAVLITLRRKQIPGVARGPAWRLIGTILGTMFFLT
Mflv_1173|M.gilvum_PYR-GCK          IARRVAFMFTALCLFASLFIMLRRKRVPGVARGPAWRLMGVIFATIFFLM
Mvan_5632|M.vanbaalenii_PYR-1       IARRVAFLFTALCLFSSLFIMLRRKRVPGVARGPAWRLMGVIFATIFFLM
MSMEG_6389|M.smegmatis_MC2_155      ISRRVAFVFTAMCLFPSLFMMLRRKHIAGVARGPAWRLMGIIFATMFFLM
TH_2242|M.thermoresistible__bu      LSRRFGFLITALSLFVSIFIMLRRKRVPGVARGPVWRLIGILFATVFVLM
MAB_0185c|M.abscessus_ATCC_199      VSRRFGFLLIAACLFIAMFILLRRKRVPGVARGPAWRVLGVVFGTIFFLM
MAV_0229|M.avium_104                VARRFAVLALVLALAVTVAMSLRKGRIPGTATGPSRRIVGITIISFVAMM
                                    ::**...:  . .*  :: : **: ::...* **  *::*  : :.. : 

Rv3795|M.tuberculosis_H37Rv         FTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLL
Mb3824|M.bovis_AF2122/97            FTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLL
MMAR_5357|M.marinum_M               FTPTKWVHHFGLFAAVGAAMAALTTVLVSPTVLRWSRNRMAFLAALLFTL
MUL_4974|M.ulcerans_Agy99           FTPTKWVHHFGLFAAVGAAMAALTTVLVSPTVLRWSRNRMAFLAALLFTL
MLBr_00104|M.leprae_Br4923          FAPTKWVHHFGLFAALGAAVAALTTVLVSHEVLRWSRNRMAFLAALLFVM
Mflv_1173|M.gilvum_PYR-GCK          FTPTKWIHHFGLFAAVGGAMAALATVLVSPAVLRSARNRMAFLAGVLFIL
Mvan_5632|M.vanbaalenii_PYR-1       FTPTKWIHHFGLFAAVGGAMAALATVLVSPVVLRSARNRMAFLAGVLFIL
MSMEG_6389|M.smegmatis_MC2_155      FTPTKWIHHFGLFAAVGGAMAALATVLVSPTVLRSARNRMAFLSLVLFVL
TH_2242|M.thermoresistible__bu      FTPTKWVHHFGLFAAVGAAMAAVATVLVSPAVLRWARNRMAFLAALLFML
MAB_0185c|M.abscessus_ATCC_199      FAPTKWVHHFGLFAALGAAVAALATVLVSPQVLRWSRNRMAVVATVLFVL
MAV_0229|M.avium_104                FTPTKWTHHFGVFAGLAGPLGALAAVAVTAAAMRSRRNRTVYAAVVLFLV
                                    *:**** ****:**.:...:.*:::* *:  .:*  *** .  : ::* :

Rv3795|M.tuberculosis_H37Rv         ALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWL
Mb3824|M.bovis_AF2122/97            ALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWL
MMAR_5357|M.marinum_M               ALCWATTNGWWYVSSYGVPFNSAMPKIAGITVSTIFFVLFALAVLYAAWL
MUL_4974|M.ulcerans_Agy99           ALCWATTNGWWYVSSYGVPFNSAMPKIAGITVSTIFFVLFALAVLYAAWL
MLBr_00104|M.leprae_Br4923          TLCFATTNGWWYVSSYGVPFNSAMPRIDGITFSTIFFILFAIVALYAYYL
Mflv_1173|M.gilvum_PYR-GCK          AMCFASTNGWWYVSNFGAPFNNSVPQLGGVTVSAVFFVLFGIAALAAFWL
Mvan_5632|M.vanbaalenii_PYR-1       ALCFASTNGWWYVSNFGAPYNNSVPQLGGVTASAVFFTLFGVAALWAFWL
MSMEG_6389|M.smegmatis_MC2_155      AFCFASTNGWWYVSNFGAPFNNSVPKVGGVQISAIFFALSAIAALWAFWL
TH_2242|M.thermoresistible__bu      ALCWATTNGWWYVSSFGVPFNNDMPEIAGIPVSAMFFALFVIAACYAFWL
MAB_0185c|M.abscessus_ATCC_199      ALSWASAAGWWYVSSFGIPFNSSMPKIAGISVSTIFFALFALAVGYAAWL
MAV_0229|M.avium_104                ALSFASVNGWWYVSNFGVPWSNAFPAWH-YAFATALLGLTVLVLLLAAWF
                                    ::.:*:. ******.:* *:.. .*       :: :: *  :.   * ::

Rv3795|M.tuberculosis_H37Rv         HFAPRGAGEG--RLIRALTT---APVPIVAGFMAAVFVASMVAGIVRQYP
Mb3824|M.bovis_AF2122/97            HFAPRGAGEG--RLIRALTT---APVPIVAGFMAAVFVASMVAGIVRQYP
MMAR_5357|M.marinum_M               HFAPRGSGEG--RLTRALTT---APVPIAAGFMAVVFVASMGIGIVRQYP
MUL_4974|M.ulcerans_Agy99           HFAPRGSGEG--RLTRALTT---APVPIAAGFMAVVFVASMGIGILRQYP
MLBr_00104|M.leprae_Br4923          HFTNTGHGEG--RLIRTLTVSFWAPIPFAAGLMTLVFIGSMVAGIVRQYP
Mflv_1173|M.gilvum_PYR-GCK          HLR--NKQDS--RLVDVLTA---APIPIAAGLMVLFMVASMAIGVVRQYP
Mvan_5632|M.vanbaalenii_PYR-1       HLR--NKQDS--RVVDALTA---APIPVAAGFMVLFMVASMAIGVVRQYP
MSMEG_6389|M.smegmatis_MC2_155      HLT--RRTES--RVVDRLTA---APIPVAAGFMVVVMMASMAIGVVRQYP
TH_2242|M.thermoresistible__bu      HFAPRDRGEN--RVVRALTT---APIPVVAGFMVVVFVASMLTGVVRQYP
MAB_0185c|M.abscessus_ATCC_199      HFSP-RREDN--RITRSITS---APVAWAAGFMVLTSICQLAIGVARQYP
MAV_0229|M.avium_104                HFVAPDDGPPKTRWGARLAGIIQSPLAIATWALVVFEVASLTLAMTDQYP
                                    *:          *    ::    :*:. .:  :.   : .:  .:  ***

Rv3795|M.tuberculosis_H37Rv         TYSNGWSNVRAFVGG-CGLADDVLVEPDTNAGFMKPLDGDSG-SWGPLGP
Mb3824|M.bovis_AF2122/97            TYSNGWSNVRAFVGG-CGLADDVLVEPDTNAGFMKPLDGDSG-SWGPLGP
MMAR_5357|M.marinum_M               TYSNGWANLRAFTGG-CGLADDVLVEPDTNAGFMTPLPGD----YGPLGP
MUL_4974|M.ulcerans_Agy99           TYSNGWANLRAFTGG-CGLADDLLVEPDTNAGFMTPLPGD----YGPLGP
MLBr_00104|M.leprae_Br4923          TYSNGWANIRALTGG-CGLADDVLVEPDSNAGYMTALPSN----YGPLGP
Mflv_1173|M.gilvum_PYR-GCK          TYSNGWANIRALAGG-CGLADDVLVEPDSNDGFLRALPG----DWGPLGA
Mvan_5632|M.vanbaalenii_PYR-1       TYSNGWANIRAFAGG-CGLADDVLVEPDSNAGFLQPIPG----RYGPLGP
MSMEG_6389|M.smegmatis_MC2_155      TYSNGWANIRAFAGG-CGLADDVLVEPDSNAGFLTPLPG----AYGPLGP
TH_2242|M.thermoresistible__bu      TYSNAWANIRALAGG-CALADDVLVEPDPNEGFLTPLDPPAGESWGPLGP
MAB_0185c|M.abscessus_ATCC_199      SYSNGWANIRELAGG-CGLADDVLVEPDANAGFLPAIGEQ---ETGALGP
MAV_0229|M.avium_104                AWSVGRSNLQALTGKTCGLAEDVLVEQDPSAGLLSPVGGPAG--SSAADA
                                    ::* . :*:: :.*  *.**:*:*** *.. * : .:        .. ..

Rv3795|M.tuberculosis_H37Rv         LGGVNPVGFTPNGVPEHTVAEAIVMKP---------NQPGTDYDWDAPTK
Mb3824|M.bovis_AF2122/97            LGGVNPVGFTPNGVPEHTVAEAIVMKP---------NQPGTDYDWDAPTK
MMAR_5357|M.marinum_M               LGGVNPVGFSPNGVPDHTVAEAMVMKP---------NQPGTDYDWDQPVK
MUL_4974|M.ulcerans_Agy99           LGGENPVGFSPNGVPDHTVAEAMVMKP---------NQPGTDYDWDQPVK
MLBr_00104|M.leprae_Br4923          LGGVNAIGFTANGVPEHTVAEAIRITP---------NQPGTDYDWEAPTK
Mflv_1173|M.gilvum_PYR-GCK          LGGTDPTGFSPNGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIE
Mvan_5632|M.vanbaalenii_PYR-1       LGGTDPAGFSPNGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIK
MSMEG_6389|M.smegmatis_MC2_155      LGGEDPQGFSPDGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIK
TH_2242|M.thermoresistible__bu      LGGVDPVGFTANGVPDRIVAEAIRLNL---------PRPGTDYDWDAPRR
MAB_0185c|M.abscessus_ATCC_199      LGGSAPSGFTADGVPDKIVAESIRMND---------SRPGTDYDWDSKDR
MAV_0229|M.avium_104                LGAGLSEAFTANGIPADVRADPVMERPGDRSFVNDEEKTGSNQAGTEGGT
                                    **.  . .*:.:*:*    *:.:              :.*::        

Rv3795|M.tuberculosis_H37Rv         LTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDD
Mb3824|M.bovis_AF2122/97            LTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDD
MMAR_5357|M.marinum_M               LKTPGINGSTVPLPYQLDPARVPLAGTYATGSQQQSKLTSAWYQLPKPDD
MUL_4974|M.ulcerans_Agy99           LKTPGINGSTVPLPYQLDPARVPLAGTYAAGSQQQSKLTSAWYHLPKPDD
MLBr_00104|M.leprae_Br4923          LKAPGINGSVVPLPYGLNPNKVPIAGTYTTGAQQQSRLTSAWYQLPKPDD
Mflv_1173|M.gilvum_PYR-GCK          LTRPGVNGSTVPLPYGLDPARVPVAGTYSTGAQQESRLASAWYELPAADD
Mvan_5632|M.vanbaalenii_PYR-1       LSRPGVNGSTVPLPYGLDPARVPVAGTYSTGPQQESRLASAWYELPPADA
MSMEG_6389|M.smegmatis_MC2_155      LDEPGINGSTVPLPYGLDPKRVPVAGTYSTEAQQESRLSSAWYELPARDE
TH_2242|M.thermoresistible__bu      LDTPGVNGSIVRLPYGLDPARVPVAGSYVEGPQQQSRLTSAWYELPARDD
MAB_0185c|M.abscessus_ATCC_199      NTTPGVNGSTVRLPYGLDPARVPIVGSYRVGPQQQAKVTSDWYRLPARDA
MAV_0229|M.avium_104                TPAPGINGSSAQLPFNLDPARTPVLGSWRSGIQVPAHLRSGWYRLPARDK
                                       **:*** . **: *:* :.*: *::    *  : : * ** **  * 

Rv3795|M.tuberculosis_H37Rv         ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGP-GALVPAGR
Mb3824|M.bovis_AF2122/97            ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGP-GALVPAGR
MMAR_5357|M.marinum_M               ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYARPGP-GPLVAAGR
MUL_4974|M.ulcerans_Agy99           ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAKPGP-GPLVAAGR
MLBr_00104|M.leprae_Br4923          ----RHPLVVVTAAGKITGNSVLHGHTYGQTVVLEYGDPGPNGGLVPAGR
Mflv_1173|M.gilvum_PYR-GCK          ----AHPLVVITAAGTITGTSVAENLTTGQTVDLEYATRGPDGAPVPAGR
Mvan_5632|M.vanbaalenii_PYR-1       ----AHPLVVITAAGTISGTSVAEADTSGQTVELEYATPGPDGAPVAAGR
MSMEG_6389|M.smegmatis_MC2_155      TERAAHPLVVITAAGTITGESVANGLTTGQTVDLEYATRGPDGTLVPAGR
TH_2242|M.thermoresistible__bu      ----AHPLVVVTAAGTITGYSVFNGRTEGQTVQLEWARRGPDGTLVPEGR
MAB_0185c|M.abscessus_ATCC_199      ----AHPLIVVTAAGTIAAKNVKG-ELSGQTLQLEYGTAGPDGAFSPLGR
MAV_0229|M.avium_104                ----ARPLLVVSAAGRFD----------PREVQVQWATDEQAAGGHPGGS
                                         :**:*::*** :            : : :::.     .   . * 

Rv3795|M.tuberculosis_H37Rv         MVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTP
Mb3824|M.bovis_AF2122/97            MVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTP
MMAR_5357|M.marinum_M               MVPDDLFGEQPKAWRNLRFARDKMPADAVAVRVVAEDLSLTPEDWIALTP
MUL_4974|M.ulcerans_Agy99           MVPDDLFGEQPKAWRNLRFARDKMPADAVAVRVVAEDLSLTPEDWIALTP
MLBr_00104|M.leprae_Br4923          LVPDDLYGEQPKAWRNLRFARSQMPFDAVAVRVVAENLSLTPEDWIAVTP
Mflv_1173|M.gilvum_PYR-GCK          VSPYDIG--PTPSWRNLRYPRSQIPTDAVAVRVIAEDLSLGQGDWVAVTP
Mvan_5632|M.vanbaalenii_PYR-1       VSPFDIG--PTPSWRNLRYPRAQIPADAVAVRVVAEDLSLGRGDWVAVTP
MSMEG_6389|M.smegmatis_MC2_155      VTPYDVG--PTPSWRNLRYPRSEIPDDAVAVRVVAEDLSLSQGDWIAVTP
TH_2242|M.thermoresistible__bu      LEPYDLG--PIPSWRNLRFDRAEIPDDAVAIRLVVEDLSLTQGDWVAVTP
MAB_0185c|M.abscessus_ATCC_199      LTPYDLG--PAPSWRNLRFARSDIPETATAVRIVAIDGSLTPGDWLAFAP
MAV_0229|M.avium_104                FQFADVG--ASPAWRNLRLPLSAIPAAATQVRLVADDEDLAPQHWIALTP
                                    .   *:      :*****     :*  *. :*::. : .*   .*:*.:*

Rv3795|M.tuberculosis_H37Rv         PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRIT
Mb3824|M.bovis_AF2122/97            PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRIT
MMAR_5357|M.marinum_M               PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHVNGVTEIPKFRIT
MUL_4974|M.ulcerans_Agy99           PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHVNGVTEIPKFRIT
MLBr_00104|M.leprae_Br4923          PRVPELRSLQEYVGSSQPVLLDWEVGLAFPCQQPMLHANGVTDIPKFRIT
Mflv_1173|M.gilvum_PYR-GCK          PRVPELRSVQEYVGSEQPVLMDWAVGLAFPCQQPMLHANGVTEIPKFRIS
Mvan_5632|M.vanbaalenii_PYR-1       PRVPEVRSVQEYIGSEQPVLMDWAVGLAFPCQQPMLHANGVTDIPKFRIS
MSMEG_6389|M.smegmatis_MC2_155      PRVPELQSVQEYVGSDQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRIS
TH_2242|M.thermoresistible__bu      PRVPELQSVQEYVGSEQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRIT
MAB_0185c|M.abscessus_ATCC_199      PRVPELKSLQEYVGSTRPVLLDWTVGLVFPCQHPMLHQYGITEVPEFRIT
MAV_0229|M.avium_104                PRIPQLRTLQDVVGSKDPVFLDWLVGLAFPCQRPFGHQNGVDETPKWRIL
                                    **:*:::::*: :**  **::** ***.****:*: *  *: : *::** 

Rv3795|M.tuberculosis_H37Rv         PDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR
Mb3824|M.bovis_AF2122/97            PDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR
MMAR_5357|M.marinum_M               PDYNAKKLDTDTWEDGVNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR
MUL_4974|M.ulcerans_Agy99           PDYNAKKLDTDTWEDGVNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR
MLBr_00104|M.leprae_Br4923          PDYSAKKIDTDTWEDGANGGLLGITDLLLRAHVMSTYLARDWGRDWGSLR
Mflv_1173|M.gilvum_PYR-GCK          PDYYAKLQSTDTWQDGLNGGLLGITDLLLRASVMPTYLSNDWGQDWGSLR
Mvan_5632|M.vanbaalenii_PYR-1       PDYFAKLQSTDTWQDGINGGLLGITDLLLRASVMSTYLSNDWGQDWGSLR
MSMEG_6389|M.smegmatis_MC2_155      PDYYAKLQSTDTWQDGINGGLLGITDLLLRASVMSTYLSQDWGQDWGSLR
TH_2242|M.thermoresistible__bu      PDYNAKRLDTDTWQDGVNGGLLGISDLLLRAHVMATYLSRDWGRDWGSLR
MAB_0185c|M.abscessus_ATCC_199      PDYDQKRKDTDTWQDGENGGLLGITDLLLRAHVMPTYLSKDWGRDWGSLR
MAV_0229|M.avium_104                PDRFGAEANSPVMDNN-GGGPLGVTELLAKATTMATYLKDDWSRDWGSLQ
                                    **      .: . ::. .** **:::** :* .*.***  **.:*****:

Rv3795|M.tuberculosis_H37Rv         KFDT-LVDAPPAQLELGTATRSGLWSPGKIRIGP
Mb3824|M.bovis_AF2122/97            KFDT-LVDAPPAQLELGTATRSGLWSPGKIRIGP
MMAR_5357|M.marinum_M               QFET-LVDAPPAQLDLGTATHSGLWSPGKIRIGP
MUL_4974|M.ulcerans_Agy99           QFET-LVDAPPAQLDLGTATHSGLWSPGKIRIGP
MLBr_00104|M.leprae_Br4923          KFDP-LVDTHPAQLDLDTATRSGWWSPGKIRIKP
Mflv_1173|M.gilvum_PYR-GCK          RFDT-IVDATPAQIELGSETHSGLSSPGSMRYRP
Mvan_5632|M.vanbaalenii_PYR-1       RFDT-IVDAQPAEIDLGDTTHSGLWSPGPMRFQP
MSMEG_6389|M.smegmatis_MC2_155      KFDT-VVEATPAELDFGSQTHSGLYSPGPLRIRP
TH_2242|M.thermoresistible__bu      RFET-IVDAEPARIDLGSATRSGLWSPGEIRIKP
MAB_0185c|M.abscessus_ATCC_199      KLDT-IVDAQPAQIEYGSQVHSGLWKPNQIRIKP
MAV_0229|M.avium_104                RLTPYYPDARPAQLLLGTATRSGLWNPAPLRH--
                                    :: .   :: **.:  .  .:**  .*  :*