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SVIYRAHRVAIANRTASRNVRVARWVAAIAGLIGFVSSVVTPLLPVVQTTATLNWPQNGQLNSVTAPLIS LTPVDITATVPCAVVAALPPSGGVVLGTAPKQGKDANLNALFIDVNSQRVDVTDRNVVILSVPRNQVAGD AGAPGCSSIEVTSTHAGTFATFVGVTDSAGNPLRGGFPDPNLRPQIVGVFTDLTGGAPSGLRLSATIDTR FSSTPTTLKRFAMMLAIITTVGALVALWRLDQLDGRRMRRLIPARWSMFTLVDVAVIFGFLLWHVIGANS SDDGYQMQMARTADHSGYMANYFRWFGSPEDPFGWYYNLLALMIHVSDASMWIRLPDLICGVACWLLLSR EVLPRLGPAIVGFKPALWAAGLVLLAAWMPFNNGLRPEGQIALGALITYVLIERAITYGRMTPVALATLT AAFTIGIQPTGLIAVAALLAGGRPMLYILVRRHRAVGAWPLVAPLLAAGTVVLTVVFAEQTLSTVLEATK VRTAIGPAQAWYTENLRYYYLILPTVDGSLSRRFGFLITALCLFTAVLITLRRKQIPGVARGPAWRLIGT ILGTMFFLTFAPTKWVHHFGLFAALGAAVAALTTVLVSHEVLRWSRNRMAFLAALLFVMTLCFATTNGWW YVSSYGVPFNSAMPRIDGITFSTIFFILFAIVALYAYYLHFTNTGHGEGRLIRTLTVSFWAPIPFAAGLM TLVFIGSMVAGIVRQYPTYSNGWANIRALTGGCGLADDVLVEPDSNAGYMTALPSNYGPLGPLGGVNAIG FTANGVPEHTVAEAIRITPNQPGTDYDWEAPTKLKAPGINGSVVPLPYGLNPNKVPIAGTYTTGAQQQSR LTSAWYQLPKPDDRHPLVVVTAAGKITGNSVLHGHTYGQTVVLEYGDPGPNGGLVPAGRLVPDDLYGEQP KAWRNLRFARSQMPFDAVAVRVVAENLSLTPEDWIAVTPPRVPELRSLQEYVGSSQPVLLDWEVGLAFPC QQPMLHANGVTDIPKFRITPDYSAKKIDTDTWEDGANGGLLGITDLLLRAHVMSTYLARDWGRDWGSLRK FDPLVDTHPAQLDLDTATRSGWWSPGKIRIKP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_00104 | embB | - | 100% (1083) | putative arabinosyl transferase |
M. leprae Br4923 | MLBr_00106 | embC | 0.0 | 43.28% (1086) | putative arabinosyl transferase |
M. leprae Br4923 | MLBr_00105 | embA | 0.0 | 39.95% (1119) | putative arabinosyl transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3824 | embB | 0.0 | 78.68% (1088) | integral membrane indolylacetylinositol arabinosyltransferase |
M. gilvum PYR-GCK | Mflv_1173 | - | 0.0 | 68.35% (1068) | cell wall arabinan synthesis protein |
M. tuberculosis H37Rv | Rv3795 | embB | 0.0 | 78.68% (1088) | integral membrane indolylacetylinositol arabinosyltransferase |
M. abscessus ATCC 19977 | MAB_0185c | - | 0.0 | 65.33% (1070) | arabinosyltransferase B |
M. marinum M | MMAR_5357 | embB | 0.0 | 78.02% (1083) | integral membrane indolylacetylinositol arabinosyltransferase |
M. avium 104 | MAV_0229 | - | 0.0 | 43.88% (1071) | arabinosyltransferase A |
M. smegmatis MC2 155 | MSMEG_6389 | - | 0.0 | 68.68% (1076) | arabinosyltransferase A |
M. thermoresistible (build 8) | TH_2242 | embB | 0.0 | 71.48% (1073) | INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE |
M. ulcerans Agy99 | MUL_4974 | embB | 0.0 | 77.29% (1083) | integral membrane indolylacetylinositol arabinosyltransferase |
M. vanbaalenii PYR-1 | Mvan_5632 | - | 0.0 | 68.41% (1070) | cell wall arabinan synthesis protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3824|M.bovis_AF2122/97 -MTQCASRRKSTPSRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPV Rv3795|M.tuberculosis_H37Rv -MTQCASRRKSTPNRAILGAFASARGTRWVATIAGLIGFVLSVATPLLPV MMAR_5357|M.marinum_M ---MSVTNETEQDTAATTASAREVRVTRWVATIAGLIGFVLSVATPLLPV MUL_4974|M.ulcerans_Agy99 ---MSVTNETEQATAATTASAREVRVTRWVATIAGLIGFVLSVATPLLPL MLBr_00104|M.leprae_Br4923 ---MSVIYRAHRVAIANRTASRNVRVARWVAAIAGLIGFVSSVVTPLLPV Mflv_1173|M.gilvum_PYR-GCK ---MRDAAVK-----------DHVRIARWVATIAGLLGFVMAVAVPLLPV Mvan_5632|M.vanbaalenii_PYR-1 MSGTSGEAVSGTSAGAVNIDARDVKIARWVATIAGLLGFVLAVSIPLLPV MSMEG_6389|M.smegmatis_MC2_155 MSGNMDEAVSGNMDEAVSAG-KDVRIARWVATIAGLLGFVLSVSIPLLPV TH_2242|M.thermoresistible__bu MS-------------------KNVRTTRWVAIITGLLGFLLAVATPLLPV MAB_0185c|M.abscessus_ATCC_199 --------MTENSVTDTAAEARKLNIARWTATVFGLLGFVLSVSIPLLPV MAV_0229|M.avium_104 --------------------------------------MLLAVATPLLPV :: :* ****: Mb3824|M.bovis_AF2122/97 VQTTAMLDWPQRGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGG--- Rv3795|M.tuberculosis_H37Rv VQTTAMLDWPQRGQLGSVTAPLISLTPVDFTATVPCDVVRAMPPAGG--- MMAR_5357|M.marinum_M VQTTAMLNWPQNGQLNSVTAPLISLTPVNLTASVPCSVVRDMPAKGG--- MUL_4974|M.ulcerans_Agy99 VQTTAMLNWPQNGQLNSVTAPLISLTPVNLTASMPCSVVRDMPAKGG--- MLBr_00104|M.leprae_Br4923 VQTTATLNWPQNGQLNSVTAPLISLTPVDITATVPCAVVAALPPSGG--- Mflv_1173|M.gilvum_PYR-GCK TQTTATLNWPQGGQFSNVTAPLISQAPVSLTATVPCDVLRDMPADGG--- Mvan_5632|M.vanbaalenii_PYR-1 TQTTATLNWPQQNRLDNVTAPLISQAPVSLTATVPCEVVRSMPADGG--- MSMEG_6389|M.smegmatis_MC2_155 TQTTATLNWPQQGRLDNVTAPLISQAPLELTATVPCSVVRDLPPEGG--- TH_2242|M.thermoresistible__bu TQTTATLNWPQDGRLANVTAPLISQAPVEMSVTVPCDLIAAMPADGG--- MAB_0185c|M.abscessus_ATCC_199 KVSTATLDWPQQGRLNNVTAPLISQTPMDMTVIVPCAVVNSAPADGA--- MAV_0229|M.avium_104 DQTTAQLNWPQNGSFGSVEAPLIGYVATDLNITVPCQAAAGLAGRGNPGK :** *:*** . : .* ****. .. .:. :** . * Mb3824|M.bovis_AF2122/97 -VVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVT---- Rv3795|M.tuberculosis_H37Rv -VVLGTAPKQGKDANLQALFVVVSAQRVDVTDRNVVILSVPREQVT---- MMAR_5357|M.marinum_M -VVLGTAPKQGKDANLQALFVVVNSKRVNVTDRNVVILSVPREQVD---- MUL_4974|M.ulcerans_Agy99 -VVLGTAPKQGKDANLQALFVVVNSKRVNVTDRNVVILSVPREQVD---- MLBr_00104|M.leprae_Br4923 -VVLGTAPKQGKDANLNALFIDVNSQRVDVTDRNVVILSVPRNQVAGDAG Mflv_1173|M.gilvum_PYR-GCK -LVFGTAPAEGRDAALNAMLVNVTEERVDVIVRNVVVASVERERIDR--- Mvan_5632|M.vanbaalenii_PYR-1 -LLLGTAPAEGRDAALNAMLVTVSDDRVDVIVRNVVVASVDRDRVA---- MSMEG_6389|M.smegmatis_MC2_155 -LVFGTAPAEGRDAALNAMLVNVTETRVDVIVRNVVVASVNRDRVA---- TH_2242|M.thermoresistible__bu -MVLGTAPKEGKEAALQGLFVNVTDDRVDITDRNVVIASVERDRVTGAAG MAB_0185c|M.abscessus_ATCC_199 -VILGTAPPEGKEAALQSLFVRVTKERLDITDRNVVIASVPRTKVA---- MAV_0229|M.avium_104 TVLLSTVPKQAPKAVDRGLLIVRANDDLVLVVRNVPVVTAPLSQVLG--- :::.*.* :. .* ..::: : : *** : :. :: Mb3824|M.bovis_AF2122/97 SPQCQRIEVTSTHAGTFANFVGLK-----DPSGAPLRSGFPDPNLRPQIV Rv3795|M.tuberculosis_H37Rv SPQCQRIEVTSTHAGTFANFVGLK-----DPSGAPLRSGFPDPNLRPQIV MMAR_5357|M.marinum_M SPQCERIEISSTHAGTFATFVGLK-----DPSGAPLRSGYPDPNLRPQIV MUL_4974|M.ulcerans_Agy99 SPQCERIEISSTHAGTFATFVGVK-----DPSGAPLRSGYPDPNLRPQIV MLBr_00104|M.leprae_Br4923 APGCSSIEVTSTHAGTFATFVGVT-----DSAGNPLRGGFPDPNLRPQIV Mflv_1173|M.gilvum_PYR-GCK GAGCERLDITSNLDGTYAEFVGLTQE-SGANAGQPQRTGYPDPNLRPAIV Mvan_5632|M.vanbaalenii_PYR-1 GPGCERIDITSNLDGTFAEFVGLTQV-SGDNAGQPQRTGYPDPNLRPAIV MSMEG_6389|M.smegmatis_MC2_155 GPDCQRIEITSNLDGTYADFVGLTQI-SGEDAGKLQRTGYPDPNLRPAIV TH_2242|M.thermoresistible__bu TPGCSRIEITSSIDGTWATFVGLTGD-DGAD-GEDLRSGFADPNLRPQIV MAB_0185c|M.abscessus_ATCC_199 SPDCRRIVITSSDKGTFATFEGLHG--DGAEKSADLRSGFPDPNLRPQIV MAV_0229|M.avium_104 -PACQRLTFTAHADKVTAEFVGLTQGPNTEHPGAPLRGEKSGYDFRPQIV . * : .:: . * * *: . * .. ::** ** Mb3824|M.bovis_AF2122/97 GVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIAL Rv3795|M.tuberculosis_H37Rv GVFTDLTGPAPPGLAVSATIDTRFSTRPTTLKLLAIIGAIVATVVALIAL MMAR_5357|M.marinum_M GVFTDLTGPAPDGLRLSATIDTRFSTTPTTLKLLAIIGAILATTVALIAL MUL_4974|M.ulcerans_Agy99 GVFTDLTGPAPDGLRLSATIDTRFSTTPTTLKLLAIIGAILATTVALIAL MLBr_00104|M.leprae_Br4923 GVFTDLTGGAPSGLRLSATIDTRFSSTPTTLKRFAMMLAIITTVGALVAL Mflv_1173|M.gilvum_PYR-GCK GVFTDLTGPAPPGLSFSADIDTRFTTHPTALKLAAIVLAIVCTVIALLAL Mvan_5632|M.vanbaalenii_PYR-1 GVFTDLTGPAPPGLSFSATIDTRYTTHPTALKLAAILLAIVSTVIALLAL MSMEG_6389|M.smegmatis_MC2_155 GVFTDLTGPAPQGLSVSAEIDTRFTTHPTALKLAAMLLAIVSTVIALLAL TH_2242|M.thermoresistible__bu GVFTDLTGPAPPGLSLSATIDTRFTTTPTPLKLAAILLAIASTVLSVLAL MAB_0185c|M.abscessus_ATCC_199 GVFTQLSGPAPQGLSLTAHIDTRFSSSPTLLKLAAMVGAVISTIIAVLAL MAV_0229|M.avium_104 GVFTDLSGPAPPGLSFSATIDTRYSSSPTPLKMAAMILGLVLTGAALVAL ****:*:* ** ** .:* ****::: ** ** *:: .: * :::** Mb3824|M.bovis_AF2122/97 WRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFG Rv3795|M.tuberculosis_H37Rv WRLDQLDGRGSIAQLLLRPFRPASSPGGMRRLIPASWRTFTLTDAVVIFG MMAR_5357|M.marinum_M WRLDRLDGRR------------------LRSLFPANWRTFTLVDAAVIFG MUL_4974|M.ulcerans_Agy99 WRLDRLDGRR------------------LRSLFPANWRTFTLVDAAMIFG MLBr_00104|M.leprae_Br4923 WRLDQLDGRR------------------MRRLIPARWSMFTLVDVAVIFG Mflv_1173|M.gilvum_PYR-GCK WRLDRLDGRR------------------MHRIIPTRWRNLTAVDVVVLGT Mvan_5632|M.vanbaalenii_PYR-1 WRLDRLDGRR------------------MHRVIPTRWRTLTAVDGVVVGG MSMEG_6389|M.smegmatis_MC2_155 WRLDRLDGRR------------------MHRLIPTRWRTVTAVDGVVVGG TH_2242|M.thermoresistible__bu WQLDRLDGRR------------------MQRWIPERWRTFTLADGTVVSA MAB_0185c|M.abscessus_ATCC_199 WRIDQTDGHR------------------MRRLIPTRWRRFDLTDTVIMSA MAV_0229|M.avium_104 HILDTADGTR------------------HRRFLPARWWSIGGLDALVIAV :* ** : :* * . * :: Mb3824|M.bovis_AF2122/97 FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL Rv3795|M.tuberculosis_H37Rv FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL MMAR_5357|M.marinum_M FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL MUL_4974|M.ulcerans_Agy99 FLLWHVIGANSSDDGYILGMARVADHAGYMSNYFRWFGSPEDPFGWYYNL MLBr_00104|M.leprae_Br4923 FLLWHVIGANSSDDGYQMQMARTADHSGYMANYFRWFGSPEDPFGWYYNL Mflv_1173|M.gilvum_PYR-GCK FAIWYVIGANSSDDGYILQMARVADHAGYMSNYFRWFGSPEDPFGWYYNL Mvan_5632|M.vanbaalenii_PYR-1 FALWYVIGANSSDDGYILQMARVADHAGYMSNYFRWFGSPEDPFGWYYNL MSMEG_6389|M.smegmatis_MC2_155 MAIWYVIGANSSDDGYILQMARTAEHAGYMANYFRWFGSPEDPFGWYYNV TH_2242|M.thermoresistible__bu FVLWHVIGANSSDDGYILGMARVAEHAGYMSNYFRWFGSPEDPFGWYYNL MAB_0185c|M.abscessus_ATCC_199 LVLWYVIGAGSSDDGYQMGMARTAEHAGYMANYFRWFGSPEDPFGWYYNL MAV_0229|M.avium_104 LTWWHFVGANTSDDGYILTMARVSEHAGYMANYYRWFGTPEAPFGWYYDL : *:.:**.:***** : ***.::*:***:**:****:** ******:: Mb3824|M.bovis_AF2122/97 LALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVAASKPAYWA Rv3795|M.tuberculosis_H37Rv LALMTHVSDASLWMRLPDLAAGLVCWLLLSREVLPRLGPAVEASKPAYWA MMAR_5357|M.marinum_M LALMTHVSDASIWMRLPDLFAGLVCWLLLSREVLPRLGPAVAASKPANWA MUL_4974|M.ulcerans_Agy99 LALMTHVSDASIWMRLPDLFAGLVCWLLLSREVLPRLGPAVAASKPANWA MLBr_00104|M.leprae_Br4923 LALMIHVSDASMWIRLPDLICGVACWLLLSREVLPRLGPAIVGFKPALWA Mflv_1173|M.gilvum_PYR-GCK LALMTQVSTASIWMRLPDLICSVICWLLLSREVLPRLGPAVIASRPALWA Mvan_5632|M.vanbaalenii_PYR-1 LALMTQVSTASIWMRLPDLVCALVCWLLLSREVLPRLGPAVSGSRAALWA MSMEG_6389|M.smegmatis_MC2_155 LALMTKVSDASIWIRLPDLICALICWLLLSREVLPRLGPAVAGSRAAMWA TH_2242|M.thermoresistible__bu LALMTQVSTASIWIRLPDLVCGLICWLLLSREVLPRLGPAVVASRPALWA MAB_0185c|M.abscessus_ATCC_199 LAIMTKFSDISLWIRLPDLIASLVCWLLISREVLPRLGPAVARSKPAAWA MAV_0229|M.avium_104 LALWAHVSTTSIWMRLPTLAMALTCWWVISREVMPRLGHAVKQNRAAAWT **: :.* *:*:*** * .: ** ::****:**** *: :.* *: Mb3824|M.bovis_AF2122/97 AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVV Rv3795|M.tuberculosis_H37Rv AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYSRLTPAALAVV MMAR_5357|M.marinum_M AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYGRLTPAALAII MUL_4974|M.ulcerans_Agy99 AAMVLLTAWMPFNNGLRPEGIIALGSLVTYVLIERSMRYGRLTPAALAII MLBr_00104|M.leprae_Br4923 AGLVLLAAWMPFNNGLRPEGQIALGALITYVLIERAITYGRMTPVALATL Mflv_1173|M.gilvum_PYR-GCK AGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT Mvan_5632|M.vanbaalenii_PYR-1 AGLVLLAAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT MSMEG_6389|M.smegmatis_MC2_155 AGLVLLGAWMPFNNGLRPEGQIATGALITYVLIERAVTSGRLTPAALAIT TH_2242|M.thermoresistible__bu AALVLLAAWMPFNNGLRPEGQIATGALITYVLIERAIISGRLTPFALAIV MAB_0185c|M.abscessus_ATCC_199 AGFVLLASWFPFNNGLRPEGQIAVGSLITWVLIERAITSRRLTPAALATI MAV_0229|M.avium_104 AAGMFLAVWLPLDNGLRPEPIIALGILLTWCSVERAVATSRLLPVAVACI *. ::* *:*::****** ** * *:*: :**:: *: * *:* Mb3824|M.bovis_AF2122/97 TAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAG Rv3795|M.tuberculosis_H37Rv TAAFTLGVQPTGLIAVAALVAGGRPMLRILVRRHRLVGTLPLVSPMLAAG MMAR_5357|M.marinum_M SAAFTLGVQPTGLIAVAALVAGGRPILRILVKRRRQVGTLPLLSPMLAAG MUL_4974|M.ulcerans_Agy99 SAAFTLGVQPTGLIAVAALVAGGRPILRILVKRRRQVGALPLLSPMLAAG MLBr_00104|M.leprae_Br4923 TAAFTIGIQPTGLIAVAALLAGGRPMLYILVRRHRAVGAWPLVAPLLAAG Mflv_1173|M.gilvum_PYR-GCK TAAFTLGIQPTGLIAVAALVAGGRPILRILMRRRQTVGLWPLLAPMLAAG Mvan_5632|M.vanbaalenii_PYR-1 TAAFTLGIQPTGLIAVAALVAGGRPILRILMRRRQLVGLWPLLAPLLAAG MSMEG_6389|M.smegmatis_MC2_155 TAAFTLGIQPTGLIAVAALLAGGRPILRIVMRRRRLVGTWPLIAPLLAAG TH_2242|M.thermoresistible__bu TAAFTLGIQPTGLIAVAALIAGGRPILRIVMRRRRLVGTWPLVAPLLAAG MAB_0185c|M.abscessus_ATCC_199 TAAFTLGIQPTGLIAVAALLAGGRPILRIIVTKHRQVGTWPLVAPMLAAG MAV_0229|M.avium_104 IGALTLFSGPTGIASIGALLVAIGPLRTILHRRITRFGALPLIAPLLAAA .*:*: ***: ::.**:.. *: *: : .* **::*:***. Mb3824|M.bovis_AF2122/97 TVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGS Rv3795|M.tuberculosis_H37Rv TVILTVVFADQTLSTVLEATRVRAKIGPSQAWYTENLRYYYLILPTVDGS MMAR_5357|M.marinum_M TIILTVVFADQTLSTVFEATRVRGKIGPSQAWYTENLRYYYLILPTVDGS MUL_4974|M.ulcerans_Agy99 TIILTVVFADQNLSTMFEATRVRGKIGPSQAWYTENLRYYYLILPTVDGS MLBr_00104|M.leprae_Br4923 TVVLTVVFAEQTLSTVLEATKVRTAIGPAQAWYTENLRYYYLILPTVDGS Mflv_1173|M.gilvum_PYR-GCK TVILAVVFADQTMATVLEATKIRTAIGPSQEWWTENLRYYYLILPTVDGA Mvan_5632|M.vanbaalenii_PYR-1 TVVLAVVFADQTLATVLEATKIRTAIGPSQEWWTENLRYYYLVLPTTDGA MSMEG_6389|M.smegmatis_MC2_155 TVILAVVFADQTIATVLEATRIRTAIGPSQEWWTENLRYYYLILPTTDGA TH_2242|M.thermoresistible__bu TVVLTVVFADQTLATVLEATRIRTDIGPSQEWYTENLRYYYLILPTVDGS MAB_0185c|M.abscessus_ATCC_199 TVILPVVFSDQTLATVFEATRIRTAIGPSQAWYTDNLRYYYMFLPTVDGS MAV_0229|M.avium_104 TVTAILIFRDQTLAGEVQASMLKRAVGPSLSWFDEHIRYERLFMASPDGS *: ::* :*.:: .:*: :: :**: *: :::** :.:.: **: Mb3824|M.bovis_AF2122/97 LSRRFGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLM Rv3795|M.tuberculosis_H37Rv LSRRFGFLITALCLFTAVFIMLRRKRIPSVARGPAWRLMGVIFGTMFFLM MMAR_5357|M.marinum_M LSRRFGFLITALCLFTAVFIMLRRKRVAGVARGPAWRLMGVIFGTMFFLM MUL_4974|M.ulcerans_Agy99 LSRRFGFLITALCLFTAVFIMLRRKRVAGVARGPAWRLMGVIFGTMFFLM MLBr_00104|M.leprae_Br4923 LSRRFGFLITALCLFTAVLITLRRKQIPGVARGPAWRLIGTILGTMFFLT Mflv_1173|M.gilvum_PYR-GCK IARRVAFMFTALCLFASLFIMLRRKRVPGVARGPAWRLMGVIFATIFFLM Mvan_5632|M.vanbaalenii_PYR-1 IARRVAFLFTALCLFSSLFIMLRRKRVPGVARGPAWRLMGVIFATIFFLM MSMEG_6389|M.smegmatis_MC2_155 ISRRVAFVFTAMCLFPSLFMMLRRKHIAGVARGPAWRLMGIIFATMFFLM TH_2242|M.thermoresistible__bu LSRRFGFLITALSLFVSIFIMLRRKRVPGVARGPVWRLIGILFATVFVLM MAB_0185c|M.abscessus_ATCC_199 VSRRFGFLLIAACLFIAMFILLRRKRVPGVARGPAWRVLGVVFGTIFFLM MAV_0229|M.avium_104 VARRFAVLALVLALAVTVAMSLRKGRIPGTATGPSRRIVGITIISFVAMM ::**...: . .* :: : **: ::...* ** *::* : :.. : Mb3824|M.bovis_AF2122/97 FTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLL Rv3795|M.tuberculosis_H37Rv FTPTKWVHHFGLFAAVGAAMAALTTVLVSPSVLRWSRNRMAFLAALFFLL MMAR_5357|M.marinum_M FTPTKWVHHFGLFAAVGAAMAALTTVLVSPTVLRWSRNRMAFLAALLFTL MUL_4974|M.ulcerans_Agy99 FTPTKWVHHFGLFAAVGAAMAALTTVLVSPTVLRWSRNRMAFLAALLFTL MLBr_00104|M.leprae_Br4923 FAPTKWVHHFGLFAALGAAVAALTTVLVSHEVLRWSRNRMAFLAALLFVM Mflv_1173|M.gilvum_PYR-GCK FTPTKWIHHFGLFAAVGGAMAALATVLVSPAVLRSARNRMAFLAGVLFIL Mvan_5632|M.vanbaalenii_PYR-1 FTPTKWIHHFGLFAAVGGAMAALATVLVSPVVLRSARNRMAFLAGVLFIL MSMEG_6389|M.smegmatis_MC2_155 FTPTKWIHHFGLFAAVGGAMAALATVLVSPTVLRSARNRMAFLSLVLFVL TH_2242|M.thermoresistible__bu FTPTKWVHHFGLFAAVGAAMAAVATVLVSPAVLRWARNRMAFLAALLFML MAB_0185c|M.abscessus_ATCC_199 FAPTKWVHHFGLFAALGAAVAALATVLVSPQVLRWSRNRMAVVATVLFVL MAV_0229|M.avium_104 FTPTKWTHHFGVFAGLAGPLGALAAVAVTAAAMRSRRNRTVYAAVVLFLV *:**** ****:**.:...:.*:::* *: .:* *** . : ::* : Mb3824|M.bovis_AF2122/97 ALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWL Rv3795|M.tuberculosis_H37Rv ALCWATTNGWWYVSSYGVPFNSAMPKIDGITVSTIFFALFAIAAGYAAWL MMAR_5357|M.marinum_M ALCWATTNGWWYVSSYGVPFNSAMPKIAGITVSTIFFVLFALAVLYAAWL MUL_4974|M.ulcerans_Agy99 ALCWATTNGWWYVSSYGVPFNSAMPKIAGITVSTIFFVLFALAVLYAAWL MLBr_00104|M.leprae_Br4923 TLCFATTNGWWYVSSYGVPFNSAMPRIDGITFSTIFFILFAIVALYAYYL Mflv_1173|M.gilvum_PYR-GCK AMCFASTNGWWYVSNFGAPFNNSVPQLGGVTVSAVFFVLFGIAALAAFWL Mvan_5632|M.vanbaalenii_PYR-1 ALCFASTNGWWYVSNFGAPYNNSVPQLGGVTASAVFFTLFGVAALWAFWL MSMEG_6389|M.smegmatis_MC2_155 AFCFASTNGWWYVSNFGAPFNNSVPKVGGVQISAIFFALSAIAALWAFWL TH_2242|M.thermoresistible__bu ALCWATTNGWWYVSSFGVPFNNDMPEIAGIPVSAMFFALFVIAACYAFWL MAB_0185c|M.abscessus_ATCC_199 ALSWASAAGWWYVSSFGIPFNSSMPKIAGISVSTIFFALFALAVGYAAWL MAV_0229|M.avium_104 ALSFASVNGWWYVSNFGVPWSNAFPAWH-YAFATALLGLTVLVLLLAAWF ::.:*:. ******.:* *:.. .* :: :: * :. * :: Mb3824|M.bovis_AF2122/97 HFAPRGAGEG--RLIRALTT---APVPIVAGFMAAVFVASMVAGIVRQYP Rv3795|M.tuberculosis_H37Rv HFAPRGAGEG--RLIRALTT---APVPIVAGFMAAVFVASMVAGIVRQYP MMAR_5357|M.marinum_M HFAPRGSGEG--RLTRALTT---APVPIAAGFMAVVFVASMGIGIVRQYP MUL_4974|M.ulcerans_Agy99 HFAPRGSGEG--RLTRALTT---APVPIAAGFMAVVFVASMGIGILRQYP MLBr_00104|M.leprae_Br4923 HFTNTGHGEG--RLIRTLTVSFWAPIPFAAGLMTLVFIGSMVAGIVRQYP Mflv_1173|M.gilvum_PYR-GCK HLR--NKQDS--RLVDVLTA---APIPIAAGLMVLFMVASMAIGVVRQYP Mvan_5632|M.vanbaalenii_PYR-1 HLR--NKQDS--RVVDALTA---APIPVAAGFMVLFMVASMAIGVVRQYP MSMEG_6389|M.smegmatis_MC2_155 HLT--RRTES--RVVDRLTA---APIPVAAGFMVVVMMASMAIGVVRQYP TH_2242|M.thermoresistible__bu HFAPRDRGEN--RVVRALTT---APIPVVAGFMVVVFVASMLTGVVRQYP MAB_0185c|M.abscessus_ATCC_199 HFSP-RREDN--RITRSITS---APVAWAAGFMVLTSICQLAIGVARQYP MAV_0229|M.avium_104 HFVAPDDGPPKTRWGARLAGIIQSPLAIATWALVVFEVASLTLAMTDQYP *: * :: :*:. .: :. : .: .: *** Mb3824|M.bovis_AF2122/97 TYSNGWSNVRAFVGG-CGLADDVLVEPDTNAGFMKPLDGDSG-SWGPLGP Rv3795|M.tuberculosis_H37Rv TYSNGWSNVRAFVGG-CGLADDVLVEPDTNAGFMKPLDGDSG-SWGPLGP MMAR_5357|M.marinum_M TYSNGWANLRAFTGG-CGLADDVLVEPDTNAGFMTPLPGD----YGPLGP MUL_4974|M.ulcerans_Agy99 TYSNGWANLRAFTGG-CGLADDLLVEPDTNAGFMTPLPGD----YGPLGP MLBr_00104|M.leprae_Br4923 TYSNGWANIRALTGG-CGLADDVLVEPDSNAGYMTALPSN----YGPLGP Mflv_1173|M.gilvum_PYR-GCK TYSNGWANIRALAGG-CGLADDVLVEPDSNDGFLRALPG----DWGPLGA Mvan_5632|M.vanbaalenii_PYR-1 TYSNGWANIRAFAGG-CGLADDVLVEPDSNAGFLQPIPG----RYGPLGP MSMEG_6389|M.smegmatis_MC2_155 TYSNGWANIRAFAGG-CGLADDVLVEPDSNAGFLTPLPG----AYGPLGP TH_2242|M.thermoresistible__bu TYSNAWANIRALAGG-CALADDVLVEPDPNEGFLTPLDPPAGESWGPLGP MAB_0185c|M.abscessus_ATCC_199 SYSNGWANIRELAGG-CGLADDVLVEPDANAGFLPAIGEQ---ETGALGP MAV_0229|M.avium_104 AWSVGRSNLQALTGKTCGLAEDVLVEQDPSAGLLSPVGGPAG--SSAADA ::* . :*:: :.* *.**:*:*** *.. * : .: .. .. Mb3824|M.bovis_AF2122/97 LGGVNPVGFTPNGVPEHTVAEAIVMKP---------NQPGTDYDWDAPTK Rv3795|M.tuberculosis_H37Rv LGGVNPVGFTPNGVPEHTVAEAIVMKP---------NQPGTDYDWDAPTK MMAR_5357|M.marinum_M LGGVNPVGFSPNGVPDHTVAEAMVMKP---------NQPGTDYDWDQPVK MUL_4974|M.ulcerans_Agy99 LGGENPVGFSPNGVPDHTVAEAMVMKP---------NQPGTDYDWDQPVK MLBr_00104|M.leprae_Br4923 LGGVNAIGFTANGVPEHTVAEAIRITP---------NQPGTDYDWEAPTK Mflv_1173|M.gilvum_PYR-GCK LGGTDPTGFSPNGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIE Mvan_5632|M.vanbaalenii_PYR-1 LGGTDPAGFSPNGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIK MSMEG_6389|M.smegmatis_MC2_155 LGGEDPQGFSPDGVPDRIIAEAIRLNN---------PQPGTDYDWNRPIK TH_2242|M.thermoresistible__bu LGGVDPVGFTANGVPDRIVAEAIRLNL---------PRPGTDYDWDAPRR MAB_0185c|M.abscessus_ATCC_199 LGGSAPSGFTADGVPDKIVAESIRMND---------SRPGTDYDWDSKDR MAV_0229|M.avium_104 LGAGLSEAFTANGIPADVRADPVMERPGDRSFVNDEEKTGSNQAGTEGGT **. . .*:.:*:* *:.: :.*:: Mb3824|M.bovis_AF2122/97 LTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDD Rv3795|M.tuberculosis_H37Rv LTSPGINGSTVPLPYGLDPARVPLAGTYTTGAQQQSTLVSAWYLLPKPDD MMAR_5357|M.marinum_M LKTPGINGSTVPLPYQLDPARVPLAGTYATGSQQQSKLTSAWYQLPKPDD MUL_4974|M.ulcerans_Agy99 LKTPGINGSTVPLPYQLDPARVPLAGTYAAGSQQQSKLTSAWYHLPKPDD MLBr_00104|M.leprae_Br4923 LKAPGINGSVVPLPYGLNPNKVPIAGTYTTGAQQQSRLTSAWYQLPKPDD Mflv_1173|M.gilvum_PYR-GCK LTRPGVNGSTVPLPYGLDPARVPVAGTYSTGAQQESRLASAWYELPAADD Mvan_5632|M.vanbaalenii_PYR-1 LSRPGVNGSTVPLPYGLDPARVPVAGTYSTGPQQESRLASAWYELPPADA MSMEG_6389|M.smegmatis_MC2_155 LDEPGINGSTVPLPYGLDPKRVPVAGTYSTEAQQESRLSSAWYELPARDE TH_2242|M.thermoresistible__bu LDTPGVNGSIVRLPYGLDPARVPVAGSYVEGPQQQSRLTSAWYELPARDD MAB_0185c|M.abscessus_ATCC_199 NTTPGVNGSTVRLPYGLDPARVPIVGSYRVGPQQQAKVTSDWYRLPARDA MAV_0229|M.avium_104 TPAPGINGSSAQLPFNLDPARTPVLGSWRSGIQVPAHLRSGWYRLPARDK **:*** . **: *:* :.*: *:: * : : * ** ** * Mb3824|M.bovis_AF2122/97 ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGP-GALVPAGR Rv3795|M.tuberculosis_H37Rv ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAMPGP-GALVPAGR MMAR_5357|M.marinum_M ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYARPGP-GPLVAAGR MUL_4974|M.ulcerans_Agy99 ----GHPLVVVTAAGKIAGNSVLHGYTPGQTVVLEYAKPGP-GPLVAAGR MLBr_00104|M.leprae_Br4923 ----RHPLVVVTAAGKITGNSVLHGHTYGQTVVLEYGDPGPNGGLVPAGR Mflv_1173|M.gilvum_PYR-GCK ----AHPLVVITAAGTITGTSVAENLTTGQTVDLEYATRGPDGAPVPAGR Mvan_5632|M.vanbaalenii_PYR-1 ----AHPLVVITAAGTISGTSVAEADTSGQTVELEYATPGPDGAPVAAGR MSMEG_6389|M.smegmatis_MC2_155 TERAAHPLVVITAAGTITGESVANGLTTGQTVDLEYATRGPDGTLVPAGR TH_2242|M.thermoresistible__bu ----AHPLVVVTAAGTITGYSVFNGRTEGQTVQLEWARRGPDGTLVPEGR MAB_0185c|M.abscessus_ATCC_199 ----AHPLIVVTAAGTIAAKNVKG-ELSGQTLQLEYGTAGPDGAFSPLGR MAV_0229|M.avium_104 ----ARPLLVVSAAGRFD----------PREVQVQWATDEQAAGGHPGGS :**:*::*** : : : :::. . . * Mb3824|M.bovis_AF2122/97 MVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTP Rv3795|M.tuberculosis_H37Rv MVPDDLYGEQPKAWRNLRFARAKMPADAVAVRVVAEDLSLTPEDWIAVTP MMAR_5357|M.marinum_M MVPDDLFGEQPKAWRNLRFARDKMPADAVAVRVVAEDLSLTPEDWIALTP MUL_4974|M.ulcerans_Agy99 MVPDDLFGEQPKAWRNLRFARDKMPADAVAVRVVAEDLSLTPEDWIALTP MLBr_00104|M.leprae_Br4923 LVPDDLYGEQPKAWRNLRFARSQMPFDAVAVRVVAENLSLTPEDWIAVTP Mflv_1173|M.gilvum_PYR-GCK VSPYDIG--PTPSWRNLRYPRSQIPTDAVAVRVIAEDLSLGQGDWVAVTP Mvan_5632|M.vanbaalenii_PYR-1 VSPFDIG--PTPSWRNLRYPRAQIPADAVAVRVVAEDLSLGRGDWVAVTP MSMEG_6389|M.smegmatis_MC2_155 VTPYDVG--PTPSWRNLRYPRSEIPDDAVAVRVVAEDLSLSQGDWIAVTP TH_2242|M.thermoresistible__bu LEPYDLG--PIPSWRNLRFDRAEIPDDAVAIRLVVEDLSLTQGDWVAVTP MAB_0185c|M.abscessus_ATCC_199 LTPYDLG--PAPSWRNLRFARSDIPETATAVRIVAIDGSLTPGDWLAFAP MAV_0229|M.avium_104 FQFADVG--ASPAWRNLRLPLSAIPAAATQVRLVADDEDLAPQHWIALTP . *: :***** :* *. :*::. : .* .*:*.:* Mb3824|M.bovis_AF2122/97 PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRIT Rv3795|M.tuberculosis_H37Rv PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHANGIAEIPKFRIT MMAR_5357|M.marinum_M PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHVNGVTEIPKFRIT MUL_4974|M.ulcerans_Agy99 PRVPDLRSLQEYVGSTQPVLLDWAVGLAFPCQQPMLHVNGVTEIPKFRIT MLBr_00104|M.leprae_Br4923 PRVPELRSLQEYVGSSQPVLLDWEVGLAFPCQQPMLHANGVTDIPKFRIT Mflv_1173|M.gilvum_PYR-GCK PRVPELRSVQEYVGSEQPVLMDWAVGLAFPCQQPMLHANGVTEIPKFRIS Mvan_5632|M.vanbaalenii_PYR-1 PRVPEVRSVQEYIGSEQPVLMDWAVGLAFPCQQPMLHANGVTDIPKFRIS MSMEG_6389|M.smegmatis_MC2_155 PRVPELQSVQEYVGSDQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRIS TH_2242|M.thermoresistible__bu PRVPELQSVQEYVGSEQPVLMDWAVGLAFPCQQPMLHANGVTEVPKFRIT MAB_0185c|M.abscessus_ATCC_199 PRVPELKSLQEYVGSTRPVLLDWTVGLVFPCQHPMLHQYGITEVPEFRIT MAV_0229|M.avium_104 PRIPQLRTLQDVVGSKDPVFLDWLVGLAFPCQRPFGHQNGVDETPKWRIL **:*:::::*: :** **::** ***.****:*: * *: : *::** Mb3824|M.bovis_AF2122/97 PDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR Rv3795|M.tuberculosis_H37Rv PDYSAKKLDTDTWEDGTNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR MMAR_5357|M.marinum_M PDYNAKKLDTDTWEDGVNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR MUL_4974|M.ulcerans_Agy99 PDYNAKKLDTDTWEDGVNGGLLGITDLLLRAHVMATYLSRDWARDWGSLR MLBr_00104|M.leprae_Br4923 PDYSAKKIDTDTWEDGANGGLLGITDLLLRAHVMSTYLARDWGRDWGSLR Mflv_1173|M.gilvum_PYR-GCK PDYYAKLQSTDTWQDGLNGGLLGITDLLLRASVMPTYLSNDWGQDWGSLR Mvan_5632|M.vanbaalenii_PYR-1 PDYFAKLQSTDTWQDGINGGLLGITDLLLRASVMSTYLSNDWGQDWGSLR MSMEG_6389|M.smegmatis_MC2_155 PDYYAKLQSTDTWQDGINGGLLGITDLLLRASVMSTYLSQDWGQDWGSLR TH_2242|M.thermoresistible__bu PDYNAKRLDTDTWQDGVNGGLLGISDLLLRAHVMATYLSRDWGRDWGSLR MAB_0185c|M.abscessus_ATCC_199 PDYDQKRKDTDTWQDGENGGLLGITDLLLRAHVMPTYLSKDWGRDWGSLR MAV_0229|M.avium_104 PDRFGAEANSPVMDNN-GGGPLGVTELLAKATTMATYLKDDWSRDWGSLQ ** .: . ::. .** **:::** :* .*.*** **.:*****: Mb3824|M.bovis_AF2122/97 KFDT-LVDAPPAQLELGTATRSGLWSPGKIRIGP Rv3795|M.tuberculosis_H37Rv KFDT-LVDAPPAQLELGTATRSGLWSPGKIRIGP MMAR_5357|M.marinum_M QFET-LVDAPPAQLDLGTATHSGLWSPGKIRIGP MUL_4974|M.ulcerans_Agy99 QFET-LVDAPPAQLDLGTATHSGLWSPGKIRIGP MLBr_00104|M.leprae_Br4923 KFDP-LVDTHPAQLDLDTATRSGWWSPGKIRIKP Mflv_1173|M.gilvum_PYR-GCK RFDT-IVDATPAQIELGSETHSGLSSPGSMRYRP Mvan_5632|M.vanbaalenii_PYR-1 RFDT-IVDAQPAEIDLGDTTHSGLWSPGPMRFQP MSMEG_6389|M.smegmatis_MC2_155 KFDT-VVEATPAELDFGSQTHSGLYSPGPLRIRP TH_2242|M.thermoresistible__bu RFET-IVDAEPARIDLGSATRSGLWSPGEIRIKP MAB_0185c|M.abscessus_ATCC_199 KLDT-IVDAQPAQIEYGSQVHSGLWKPNQIRIKP MAV_0229|M.avium_104 RLTPYYPDARPAQLLLGTATRSGLWNPAPLRH-- :: . :: **.: . .:** .* :*