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M. tuberculosis H37Rv Rv3791 (-)

annotation: short chain dehydrogenase
coordinates: 4237165 - 4237929
length: 254

MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGARSVELIDFDA
LDTDSHPKMIEAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFG
QIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTRMSAHLKEAPLTVDK
EYVANLAVTASAKGKELVWAPAAFRYVMMVLRHIPRSIFRKLPI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3791--100% (254)short chain dehydrogenase
M. tuberculosis H37RvRv2073c-2e-4342.39% (243) shortchain dehydrogenase
M. tuberculosis H37RvRv1350fabG3e-1228.50% (193) 3-ketoacyl-(acyl-carrier-protein) reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3820-1e-140100.00% (254) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1177-1e-10876.92% (260) short chain dehydrogenase
M. leprae Br4923MLBr_00108-1e-12688.98% (254) short chain dehydrogenase
M. abscessus ATCC 19977MAB_0191c-1e-10067.95% (259) short chain dehydrogenase
M. marinum MMMAR_5353-1e-12890.55% (254) short-chain type dehydrogenase/reductase
M. avium 104MAV_0231-1e-12588.19% (254) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_6385-1e-12185.04% (254) short chain dehydrogenase
M. thermoresistible (build 8)TH_1604-1e-11887.55% (241) PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. ulcerans Agy99MUL_4970-1e-12990.55% (254) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_5628-1e-10977.69% (260) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1177|M.gilvum_PYR-GCK          MVLDATGNPQAILLLGGTSEIALAIGERYLRNARARVILADLPGHPRKDA
Mvan_5628|M.vanbaalenii_PYR-1       MVFDATGNPQTILLLGGTSEIALAIAERYLRNARARIVLADLPDHPRKDA
Rv3791|M.tuberculosis_H37Rv         MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRRED
Mb3820|M.bovis_AF2122/97            MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRRED
MMAR_5353|M.marinum_M               MVLDAVGNPQSVLLLGGTSEIGLAICQRYLRNAPARIVLACLPDDPGRDD
MUL_4970|M.ulcerans_Agy99           MVLDAVGNPQSVLLLGGTSEIGLAICQRYLRNAPARIVLACLPDDPGRDD
MLBr_00108|M.leprae_Br4923          MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNRED
MAV_0231|M.avium_104                MVLDAVGNPQTILLLGGTSEIGLAICERYLQNAHARIILAAMPGDPGRDA
TH_1604|M.thermoresistible__bu      -------------LLGGTSEIGLAICERYLQNAPARIVLAALPDDPNRDA
MSMEG_6385|M.smegmatis_MC2_155      MVFDAVGNPQTILLLGGTSEIGLAICERYLRNASARIVLAVMPGDPGRDA
MAB_0191c|M.abscessus_ATCC_199      -MIDATGNPQTILLFGGTSEIGLAIVERYLKNAKARVILADLPNAPKREA
                                                 *:******.*** :***:*: **::** :*. * :: 

Mflv_1177|M.gilvum_PYR-GCK          AIAQMEAAGAKSVEWIDFDALDTENHPNVIDAAWRDGDVDVAVVAFGLLG
Mvan_5628|M.vanbaalenii_PYR-1       AVEQMRAAGAKAVDWIDFDALDTDNHPKVIDTAWRDGDVDVAVVAFGLLG
Rv3791|M.tuberculosis_H37Rv         AAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLG
Mb3820|M.bovis_AF2122/97            AAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLG
MMAR_5353|M.marinum_M               AVAQMKAAGASSVELIDFDAMDTDSHPKVIEQAFGGGDVDVAIVAFGLLG
MUL_4970|M.ulcerans_Agy99           AVAQMKAAGASSVELIDFDAMDTDSHPKVIEQAFGGGDVDVAIVAFGLLG
MLBr_00108|M.leprae_Br4923          AVAQMTAVGARSVELIDFEALDTDSHPRMIEQAFTGGDVDVAIVAFGLLG
MAV_0231|M.avium_104                AVEQMKAAGARSVEVIDFEATDTDTHPKMIEQAFAGGDVDVAIVAFGILG
TH_1604|M.thermoresistible__bu      AVEQMRRAGAKSVELIDFDAVDTESHPAVIDKAFANGDIDVAIVAFGLLG
MSMEG_6385|M.smegmatis_MC2_155      AVEQMRKAGASAVDVVDFDALDTESHPAVIDQAFAGGDVDVAIVAFGLLG
MAB_0191c|M.abscessus_ATCC_199      AIEQIRAAGAKEVQYVEFDALDTKSHPALIESAWAQGDVDVAIVAFGILG
                                    *   :  .**  *: ::*:* **..** :*: *:  **:***:****:**

Mflv_1177|M.gilvum_PYR-GCK          DAEELWQNQRKAVQIAGINYTAAVSVGVLLGEKMRAQGSGRIIAMSSAAG
Mvan_5628|M.vanbaalenii_PYR-1       DAEELWQNQRKAVQIAGINYTAAVSVGVLLGEKMRAQGSGRIIAMSSAAG
Rv3791|M.tuberculosis_H37Rv         DAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAG
Mb3820|M.bovis_AF2122/97            DAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAG
MMAR_5353|M.marinum_M               DAEELWQNQHKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIAMSTVAG
MUL_4970|M.ulcerans_Agy99           DAEELWQNQHKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIAMSTVAG
MLBr_00108|M.leprae_Br4923          DAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIVMSSAAG
MAV_0231|M.avium_104                DAEELWQDQRKAVQAAEINYTAAVSVGVLLAEKMRGQGFGQIIAMSSAAG
TH_1604|M.thermoresistible__bu      DAEELWQNQRKAVQIAQINYTAAVSVGVLLGEKMRAQGFGQIIAMSSAAG
MSMEG_6385|M.smegmatis_MC2_155      DAEELWQNQRKAVQIAGVNYTAAVSVGVLLGEKMRAQGSGQIIAMSSAAG
MAB_0191c|M.abscessus_ATCC_199      DAEELWQDQTKAVLSAQVNYTAAVSVGVLIGQKMKAQGFGQVIAMSSVAG
                                    *******:* ***  * :***********:.:**:.** *::*.**:.**

Mflv_1177|M.gilvum_PYR-GCK          ERVRRSNFVYGSTKAGLDGFYLGLGEALRDYGVRVLVIRPGQVRTTTTVE
Mvan_5628|M.vanbaalenii_PYR-1       ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTTTTME
Rv3791|M.tuberculosis_H37Rv         ERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTR----
Mb3820|M.bovis_AF2122/97            ERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTR----
MMAR_5353|M.marinum_M               ERVRRSNFVYGSTKAGLDGFYLGLSEALREHGVRVLVIRPGQVRTR----
MUL_4970|M.ulcerans_Agy99           ERVRRSNFVYGSTKAGLDGFYLGLSEALREHGVRVLVIRPGQVRTR----
MLBr_00108|M.leprae_Br4923          ERVRRSNFVYGSTKAGLDGFYLGLSEALHEYGVHVLVIRPGQVRTR----
MAV_0231|M.avium_104                ERVRRSNFVYGSTKAGLDGFYLGLGEALREYGVRVLVIRPGQVRTR----
TH_1604|M.thermoresistible__bu      ERVRRSNFVYGSTKAGLDGFYLGLGEALREYGVRVLVIRPGQVRTR----
MSMEG_6385|M.smegmatis_MC2_155      ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTR----
MAB_0191c|M.abscessus_ATCC_199      ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVVRPGQVRTTTTIE
                                    *****:******************.***::.**:***:*******     

Mflv_1177|M.gilvum_PYR-GCK          HWKATGAKEAPFTVDKEDVAELAVTASNKGKDLIWAPGPFRFVMMVLRHI
Mvan_5628|M.vanbaalenii_PYR-1       HWKATGAKEAPFTVDKEDVAELAVTASNKGKDLIWAPGAFRFVMMVLRHI
Rv3791|M.tuberculosis_H37Rv         --MSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMVLRHI
Mb3820|M.bovis_AF2122/97            --MSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMVLRHI
MMAR_5353|M.marinum_M               --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
MUL_4970|M.ulcerans_Agy99           --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
MLBr_00108|M.leprae_Br4923          --MSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMVLRHI
MAV_0231|M.avium_104                --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
TH_1604|M.thermoresistible__bu      --MSAHIKEAPLTVDKEYVANLAVTAAAKGKELVWAPGAFRYVMMVLRHI
MSMEG_6385|M.smegmatis_MC2_155      --MSAHVKEAPLTVDKEYVAELAVTASAKGKELVWAPGAFRYVMMVLRHI
MAB_0191c|M.abscessus_ATCC_199      HWKATGAKEAPFTVDKEEIAELVVASAAAGKELIWAPGQWRFVMSVLRHV
                                       ::  ****:**:** :*:*.*:::  **:*:***. :*:** ****:

Mflv_1177|M.gilvum_PYR-GCK          PRPIFRKLPI
Mvan_5628|M.vanbaalenii_PYR-1       PRPIFRKLPI
Rv3791|M.tuberculosis_H37Rv         PRSIFRKLPI
Mb3820|M.bovis_AF2122/97            PRSIFRKLPI
MMAR_5353|M.marinum_M               PRSIFRRLPI
MUL_4970|M.ulcerans_Agy99           PRSIFRRLPI
MLBr_00108|M.leprae_Br4923          PRSIFRKLPI
MAV_0231|M.avium_104                PRPIFRKLPI
TH_1604|M.thermoresistible__bu      PRPIFRKLPI
MSMEG_6385|M.smegmatis_MC2_155      PRPIFRKLPI
MAB_0191c|M.abscessus_ATCC_199      PRPLFRKLPV
                                    **.:**:**: