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MVFDATGNPQTILLLGGTSEIALAIAERYLRNARARIVLADLPDHPRKDAAVEQMRAAGAKAVDWIDFDA LDTDNHPKVIDTAWRDGDVDVAVVAFGLLGDAEELWQNQRKAVQIAGINYTAAVSVGVLLGEKMRAQGSG RIIAMSSAAGERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTTTTMEHWKATGAKEA PFTVDKEDVAELAVTASNKGKDLIWAPGAFRFVMMVLRHIPRPIFRKLPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5628 | - | - | 100% (260) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_3435 | - | 2e-40 | 38.74% (253) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_0690 | - | 7e-12 | 27.87% (244) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3820 | - | 1e-109 | 77.69% (260) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1177 | - | 1e-139 | 93.08% (260) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv3791 | - | 1e-109 | 77.69% (260) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00108 | - | 1e-106 | 75.00% (260) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0191c | - | 1e-118 | 76.45% (259) | short chain dehydrogenase |
| M. marinum M | MMAR_5353 | - | 1e-109 | 77.69% (260) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_0231 | - | 1e-110 | 77.69% (260) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6385 | - | 1e-118 | 83.85% (260) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_1604 | - | 1e-109 | 81.38% (247) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4970 | - | 1e-109 | 77.69% (260) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5628|M.vanbaalenii_PYR-1 MVFDATGNPQTILLLGGTSEIALAIAERYLRNARARIVLADLPDHPRKDA
Mflv_1177|M.gilvum_PYR-GCK MVLDATGNPQAILLLGGTSEIALAIGERYLRNARARVILADLPGHPRKDA
MMAR_5353|M.marinum_M MVLDAVGNPQSVLLLGGTSEIGLAICQRYLRNAPARIVLACLPDDPGRDD
MUL_4970|M.ulcerans_Agy99 MVLDAVGNPQSVLLLGGTSEIGLAICQRYLRNAPARIVLACLPDDPGRDD
MLBr_00108|M.leprae_Br4923 MVLDAVGHPQTVLLLGGTSEIGLAICKRYLRNAPARIVLAAMPDDPNRED
Mb3820|M.bovis_AF2122/97 MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRRED
Rv3791|M.tuberculosis_H37Rv MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRRED
MAV_0231|M.avium_104 MVLDAVGNPQTILLLGGTSEIGLAICERYLQNAHARIILAAMPGDPGRDA
TH_1604|M.thermoresistible__bu -------------LLGGTSEIGLAICERYLQNAPARIVLAALPDDPNRDA
MSMEG_6385|M.smegmatis_MC2_155 MVFDAVGNPQTILLLGGTSEIGLAICERYLRNASARIVLAVMPGDPGRDA
MAB_0191c|M.abscessus_ATCC_199 -MIDATGNPQTILLFGGTSEIGLAIVERYLKNAKARVILADLPNAPKREA
*:******.*** :***:*: **::** :*. * ::
Mvan_5628|M.vanbaalenii_PYR-1 AVEQMRAAGAKAVDWIDFDALDTDNHPKVIDTAWRDGDVDVAVVAFGLLG
Mflv_1177|M.gilvum_PYR-GCK AIAQMEAAGAKSVEWIDFDALDTENHPNVIDAAWRDGDVDVAVVAFGLLG
MMAR_5353|M.marinum_M AVAQMKAAGASSVELIDFDAMDTDSHPKVIEQAFGGGDVDVAIVAFGLLG
MUL_4970|M.ulcerans_Agy99 AVAQMKAAGASSVELIDFDAMDTDSHPKVIEQAFGGGDVDVAIVAFGLLG
MLBr_00108|M.leprae_Br4923 AVAQMTAVGARSVELIDFEALDTDSHPRMIEQAFTGGDVDVAIVAFGLLG
Mb3820|M.bovis_AF2122/97 AAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLG
Rv3791|M.tuberculosis_H37Rv AAAAMKQAGARSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLG
MAV_0231|M.avium_104 AVEQMKAAGARSVEVIDFEATDTDTHPKMIEQAFAGGDVDVAIVAFGILG
TH_1604|M.thermoresistible__bu AVEQMRRAGAKSVELIDFDAVDTESHPAVIDKAFANGDIDVAIVAFGLLG
MSMEG_6385|M.smegmatis_MC2_155 AVEQMRKAGASAVDVVDFDALDTESHPAVIDQAFAGGDVDVAIVAFGLLG
MAB_0191c|M.abscessus_ATCC_199 AIEQIRAAGAKEVQYVEFDALDTKSHPALIESAWAQGDVDVAIVAFGILG
* : .** *: ::*:* **..** :*: *: **:***:****:**
Mvan_5628|M.vanbaalenii_PYR-1 DAEELWQNQRKAVQIAGINYTAAVSVGVLLGEKMRAQGSGRIIAMSSAAG
Mflv_1177|M.gilvum_PYR-GCK DAEELWQNQRKAVQIAGINYTAAVSVGVLLGEKMRAQGSGRIIAMSSAAG
MMAR_5353|M.marinum_M DAEELWQNQHKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIAMSTVAG
MUL_4970|M.ulcerans_Agy99 DAEELWQNQHKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIAMSTVAG
MLBr_00108|M.leprae_Br4923 DAEELWQNQSKAVQIAEINYTAAVSVGVLLGEKMRAQGFGQIIVMSSAAG
Mb3820|M.bovis_AF2122/97 DAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAG
Rv3791|M.tuberculosis_H37Rv DAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAG
MAV_0231|M.avium_104 DAEELWQDQRKAVQAAEINYTAAVSVGVLLAEKMRGQGFGQIIAMSSAAG
TH_1604|M.thermoresistible__bu DAEELWQNQRKAVQIAQINYTAAVSVGVLLGEKMRAQGFGQIIAMSSAAG
MSMEG_6385|M.smegmatis_MC2_155 DAEELWQNQRKAVQIAGVNYTAAVSVGVLLGEKMRAQGSGQIIAMSSAAG
MAB_0191c|M.abscessus_ATCC_199 DAEELWQDQTKAVLSAQVNYTAAVSVGVLIGQKMKAQGFGQVIAMSSVAG
*******:* *** * :***********:.:**:.** *::*.**:.**
Mvan_5628|M.vanbaalenii_PYR-1 ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTTTTME
Mflv_1177|M.gilvum_PYR-GCK ERVRRSNFVYGSTKAGLDGFYLGLGEALRDYGVRVLVIRPGQVRTTTTVE
MMAR_5353|M.marinum_M ERVRRSNFVYGSTKAGLDGFYLGLSEALREHGVRVLVIRPGQVRTR----
MUL_4970|M.ulcerans_Agy99 ERVRRSNFVYGSTKAGLDGFYLGLSEALREHGVRVLVIRPGQVRTR----
MLBr_00108|M.leprae_Br4923 ERVRRSNFVYGSTKAGLDGFYLGLSEALHEYGVHVLVIRPGQVRTR----
Mb3820|M.bovis_AF2122/97 ERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTR----
Rv3791|M.tuberculosis_H37Rv ERVRRANFVYGSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTR----
MAV_0231|M.avium_104 ERVRRSNFVYGSTKAGLDGFYLGLGEALREYGVRVLVIRPGQVRTR----
TH_1604|M.thermoresistible__bu ERVRRSNFVYGSTKAGLDGFYLGLGEALREYGVRVLVIRPGQVRTR----
MSMEG_6385|M.smegmatis_MC2_155 ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTR----
MAB_0191c|M.abscessus_ATCC_199 ERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVVRPGQVRTTTTIE
*****:******************.***::.**:***:*******
Mvan_5628|M.vanbaalenii_PYR-1 HWKATGAKEAPFTVDKEDVAELAVTASNKGKDLIWAPGAFRFVMMVLRHI
Mflv_1177|M.gilvum_PYR-GCK HWKATGAKEAPFTVDKEDVAELAVTASNKGKDLIWAPGPFRFVMMVLRHI
MMAR_5353|M.marinum_M --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
MUL_4970|M.ulcerans_Agy99 --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
MLBr_00108|M.leprae_Br4923 --MSAHVKEAPLTVNKEYVADLAVTAAAKGKELVWAPATFRYVMMVLRHI
Mb3820|M.bovis_AF2122/97 --MSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMVLRHI
Rv3791|M.tuberculosis_H37Rv --MSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMVLRHI
MAV_0231|M.avium_104 --MSAHVKEAPLTVDKEYVANLAVTAAAKGKELVWAPAAFRYVMMVLRHI
TH_1604|M.thermoresistible__bu --MSAHIKEAPLTVDKEYVANLAVTAAAKGKELVWAPGAFRYVMMVLRHI
MSMEG_6385|M.smegmatis_MC2_155 --MSAHVKEAPLTVDKEYVAELAVTASAKGKELVWAPGAFRYVMMVLRHI
MAB_0191c|M.abscessus_ATCC_199 HWKATGAKEAPFTVDKEEIAELVVASAAAGKELIWAPGQWRFVMSVLRHV
:: ****:**:** :*:*.*::: **:*:***. :*:** ****:
Mvan_5628|M.vanbaalenii_PYR-1 PRPIFRKLPI
Mflv_1177|M.gilvum_PYR-GCK PRPIFRKLPI
MMAR_5353|M.marinum_M PRSIFRRLPI
MUL_4970|M.ulcerans_Agy99 PRSIFRRLPI
MLBr_00108|M.leprae_Br4923 PRSIFRKLPI
Mb3820|M.bovis_AF2122/97 PRSIFRKLPI
Rv3791|M.tuberculosis_H37Rv PRSIFRKLPI
MAV_0231|M.avium_104 PRPIFRKLPI
TH_1604|M.thermoresistible__bu PRPIFRKLPI
MSMEG_6385|M.smegmatis_MC2_155 PRPIFRKLPI
MAB_0191c|M.abscessus_ATCC_199 PRPLFRKLPV
**.:**:**: