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MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGALIVLGHDENVEAICDGGFSLDVRYAATRLRELCK MDGAVVLSTDGSRIVRANVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGERHV LTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVMTVVQRLELVRRIGLVIDYDVVEL GTDGRQLRLQLDELLGGNDTARELIVRDYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPT TTEAQDSTLSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGAMWARHVREGLSQL AESTISDQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3586 | - | - | 100% (358) | hypothetical protein Rv3586 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3617 | - | 0.0 | 99.44% (358) | DNA integrity scanning protein DisA |
| M. gilvum PYR-GCK | Mflv_1441 | - | 1e-167 | 83.10% (355) | DNA integrity scanning protein DisA |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0562c | - | 1e-156 | 77.31% (357) | DNA integrity scanning protein DisA |
| M. marinum M | MMAR_5086 | - | 1e-180 | 89.66% (358) | putative RuvA-like protein |
| M. avium 104 | MAV_0567 | - | 1e-179 | 91.24% (354) | DNA integrity scanning protein DisA |
| M. smegmatis MC2 155 | MSMEG_6080 | - | 1e-167 | 83.66% (355) | DNA integrity scanning protein DisA |
| M. thermoresistible (build 8) | TH_0588 | - | 1e-167 | 82.87% (356) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4162 | - | 1e-179 | 89.11% (358) | DNA integrity scanning protein DisA |
| M. vanbaalenii PYR-1 | Mvan_5343 | - | 1e-168 | 83.38% (355) | DNA integrity scanning protein DisA |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3586|M.tuberculosis_H37Rv -------------MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGAL
Mb3617|M.bovis_AF2122/97 -------------MHAVTRPTLREAVARLAPGTGLRDGLERILRGRTGAL
MMAR_5086|M.marinum_M -------------MHAVNRPTLREAVARLAPGTGLRDGLERILRGRTGAL
MUL_4162|M.ulcerans_Agy99 -------------MHAVNRPTLREAVARLAPGTGLRDGLERILRGRTGAL
MAV_0567|M.avium_104 ----------------MTRPTLRETVARLAPGTGLRDGLERILRGRTGAL
MSMEG_6080|M.smegmatis_MC2_155 MAVKSG-ARSGRNVVHLARPTLRETLGRLAPGTPLRDGLERILRGRTGAL
TH_0588|M.thermoresistible__bu MAVTSG-KRAGRTVVSLARPTMRETLGRLAPGTPLRDGLERILRGRTGAL
Mflv_1441|M.gilvum_PYR-GCK MAVKSSAGRSTRTVVPMTRPTLRETIARLAPGTPLRDGLERILRGRTGAL
Mvan_5343|M.vanbaalenii_PYR-1 MAVKSSSARAARTVVPLVRPTLRETIARLAPGTPLRDGLERILRGRTGAL
MAB_0562c|M.abscessus_ATCC_199 ------------MDNAEANARMRETLARLAPGTPLRDGLERILRGRTGAL
.. :**::.****** ****************
Rv3586|M.tuberculosis_H37Rv IVLGHDENVEAICDGGFSLDVRYAATRLRELCKMDGAVVLSTDGSRIVRA
Mb3617|M.bovis_AF2122/97 IVLGHDENVEAICDGGFSLDVRYAATRLRELCKMDGAVVLSTDGSRIVRA
MMAR_5086|M.marinum_M IVLGHDENVEAICDGGFPLDVRYAPTRLRELCKMDGAVVLSTDGSRFIRA
MUL_4162|M.ulcerans_Agy99 IVLGHDENVEAICDGGFPLDVRYAPTRLRELCKMDGAVVLSTDGSRFIRA
MAV_0567|M.avium_104 IVLGNDENVEAICDGGFALDVRYAPTRLRELAKMDGAVVLSTDGSRIVRA
MSMEG_6080|M.smegmatis_MC2_155 IVLGYDDSVEAICDGGFVLDVRYAPTRLRELSKMDGAVVLSSDGSRILRA
TH_0588|M.thermoresistible__bu IVLGYDDSVEAICDGGFPLDVRYAPTRLRELSKMDGAIVLSSDGSRILRA
Mflv_1441|M.gilvum_PYR-GCK IVIGYDDSVETICDGGFSLDVRYAPTRLRELSKMDGAVVLSSDGSRILRA
Mvan_5343|M.vanbaalenii_PYR-1 IVIGYDDSVETICDGGFSLDVRYAPTRLRELSKMDGAVVLSSDGSRILRA
MAB_0562c|M.abscessus_ATCC_199 IVLGYDDKVESICDGGFSLDVAFAPTRLRELSKMDGAVVLSTDGSRIVRA
**:* *:.**:****** *** :*.******.*****:***:****::**
Rv3586|M.tuberculosis_H37Rv NVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGE
Mb3617|M.bovis_AF2122/97 NVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVRGE
MMAR_5086|M.marinum_M NVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVGGE
MUL_4162|M.ulcerans_Agy99 NVQLVPDPSIPTDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVGGE
MAV_0567|M.avium_104 NVQLVPDPSIATDESGTRHRSAERAAIQTGYPVISVSHSMNIVTVYVGGE
MSMEG_6080|M.smegmatis_MC2_155 NVQLVPDPSIPTDESGTRHRSAERTAIQTGYPVISVSHSMSIVTVYVAGE
TH_0588|M.thermoresistible__bu NVQLVPDPSIPTDESGTRHRSAERTAIQTGYPVISVSHSMSIVTVYVAGE
Mflv_1441|M.gilvum_PYR-GCK NVQLVPDPSIPTEESGTRHRSAERTAIQTGYPVISVSHSMSIVTVYVAGE
Mvan_5343|M.vanbaalenii_PYR-1 NVQLVPDPSIPTEESGTRHRSAERTAIQTGYPVISVSHSMSIVTVYVAGE
MAB_0562c|M.abscessus_ATCC_199 NVQLVPDPSIPTDESGTRHRSAERTAIQTDYPVVSVSHSMNIVSVYTAGI
**********.*:***********:****.***:******.**:**. *
Rv3586|M.tuberculosis_H37Rv RHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVM
Mb3617|M.bovis_AF2122/97 RHVLTDSATILSRANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVM
MMAR_5086|M.marinum_M RHVLSDSATILSHANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVM
MUL_4162|M.ulcerans_Agy99 RHVLSDSATILSHANQAIATLERYKTRLDEVSRQLSRAEIEDFVTLRDVM
MAV_0567|M.avium_104 RHVVADSATILSRANQAIATLERYKIRLDEVSRQLSRAEIEDFVTLRDVL
MSMEG_6080|M.smegmatis_MC2_155 RHVVPDSATILSRANQTIATLERYKGRLDEVSRQLSTAEIEDFVTLRDVM
TH_0588|M.thermoresistible__bu RHVMPDSATILSRANQTIATLERYKTRLDEVLRQLSAAEIEDFVTLRDVM
Mflv_1441|M.gilvum_PYR-GCK RHVVPESATILSRANQTIDTLERYKTRLEEVSRQLSTAEIEDFVTLRDVM
Mvan_5343|M.vanbaalenii_PYR-1 RHVVPESATILSRANQTIDTLERYKTRLDEVSRQLSMAEIEDFVTLRDVM
MAB_0562c|M.abscessus_ATCC_199 RHVVMDSATVMSRVNQAVSTLERYKTRLDEVTSSLSTAEIEDFVTLRDVM
***: :***::*:.**:: ****** **:** .** ************:
Rv3586|M.tuberculosis_H37Rv TVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVR
Mb3617|M.bovis_AF2122/97 TVVQRLELVRRIGLVIDYDVVELGTDGRQLRLQLDELLGGNDTARELIVR
MMAR_5086|M.marinum_M TVVQRLELVRRIGIEIDNDVVELGTDGRQLRLQLEELLGDNETARELIVR
MUL_4162|M.ulcerans_Agy99 TVVQRLELVRRIGIEIDNDVVELGTDGRQLRLQLEELLGDNETARELIVR
MAV_0567|M.avium_104 TVVQRLELVRRIGQVIDNDVVELGTDGRQLRLQLDELLGGNDNARELIVR
MSMEG_6080|M.smegmatis_MC2_155 TVVQRLEMVRRISLEIDADVVELGTDGRQLKLQLDELVGDNETARELIVR
TH_0588|M.thermoresistible__bu TVVQRLEMVRRISLEIDADVVELGTDGRQVKLQLEELVGDNDTARELIVR
Mflv_1441|M.gilvum_PYR-GCK TVVQRLEMVRRISLELDSDVVELGTDGRQLKLQLDELVGDNDVDRELIVR
Mvan_5343|M.vanbaalenii_PYR-1 TVVQRLEMVRRISLEIDSDVVELGTDGRQLKLQLDELVGDNDTDRELLVR
MAB_0562c|M.abscessus_ATCC_199 TVAQRLELVRRISQDIELDVIELGTDGRQLKLQIGELVGDNDTERELLVR
**.****:****. :: **:********::**: **:*.*: ***:**
Rv3586|M.tuberculosis_H37Rv DYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDS
Mb3617|M.bovis_AF2122/97 DYHANPEPPSTGQINATLDELDALSDGDLLDFTALAKVFGYPTTTEAQDS
MMAR_5086|M.marinum_M DYYANHEPLATAQITATLDELDAITDTELLDFNALAKIFGYPSTTEAQDS
MUL_4162|M.ulcerans_Agy99 DYYANHEPLATAQITATLDELDAITDTELLDFNALAKIFGYPSTTEAQDS
MAV_0567|M.avium_104 DYHASPEPLSEAQMTATLDELDALSDTELLDFTALAKVFGYPTTTEAQDS
MSMEG_6080|M.smegmatis_MC2_155 DYHANPDPPTAAQVAATLEELDSLSDSELLDFTVLARVFGYPSTAEAQDS
TH_0588|M.thermoresistible__bu DYHANPDPPDAAQIAATLDDLDSLSDNELLDFTVLAAVFGYPSTPEAQDS
Mflv_1441|M.gilvum_PYR-GCK DYHANPDPPTSAQVTATLEELDSLSDNELLAFTTLARVFGYPSTAEAQDS
Mvan_5343|M.vanbaalenii_PYR-1 DYHANPDPPTSAQVTATLEELDALSDSELLDFTTLARVFGYPSTAEAQDS
MAB_0562c|M.abscessus_ATCC_199 DYHANPEPPTQAQIASTLEDLDALSDTDLLDLTVLSRTFGYPSTVEAQDT
**:*. :* .*: :**::**:::* :** :..*: ****:* ****:
Rv3586|M.tuberculosis_H37Rv TLSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGA
Mb3617|M.bovis_AF2122/97 ALSPRGYRAMAGIPRLQFAHADLLVRAFGTLQGLLAASAGDLQSVDGIGA
MMAR_5086|M.marinum_M ALSPRGYRAMSGIPRLQFSHTDLLVRAFGSLQGLLAASASDLQSVEGIGA
MUL_4162|M.ulcerans_Agy99 ALSPRGYRAMSGIPRLQFSHTDLLVRAFGSLHGLLAASASDLQSVEGIGS
MAV_0567|M.avium_104 AVSPRGYRALAGIPRLQFAHADLLVRSFGTLQNVLAASASDLQSIDGIGA
MSMEG_6080|M.smegmatis_MC2_155 AMSSRGYRAMAAIPRLQFAHVDLLVRSFGSLQNLLAASADDLQSVDGIGS
TH_0588|M.thermoresistible__bu AVSSRGYRAMAGIPRLQFAHVELLVRSFGSLQDLLAASAADLQSVEGIGS
Mflv_1441|M.gilvum_PYR-GCK AMSSRGYRAMAGIPRLQFAHVDLLVRNFGSLQGLLAASASDLQSVDGIGS
Mvan_5343|M.vanbaalenii_PYR-1 AMSSRGYRAMSGIPRLQFAHVDLLVRNFGSLQGLLAATATDLQSVDGIGS
MAB_0562c|M.abscessus_ATCC_199 AMSSRGYRAMTHIPRLQFAHIDRLVRAFGSLQGLLAASATDLQSVEGIGA
::*.*****:: ******:* : *** **:*:.:***:* ****::***:
Rv3586|M.tuberculosis_H37Rv MWARHVREGLSQLAESTISDQ--
Mb3617|M.bovis_AF2122/97 MWARHVRDGLSQLAESTISDQ--
MMAR_5086|M.marinum_M TWAPHVREGLSQLAESTIADQ--
MUL_4162|M.ulcerans_Agy99 TWAPHVREGLSQLAESTIADQ--
MAV_0567|M.avium_104 MWARHVREGLSQLAESTITDSLS
MSMEG_6080|M.smegmatis_MC2_155 MWARHIREGLSLLAESTIADRLA
TH_0588|M.thermoresistible__bu MWARHIREGLSQLAESTIADRLA
Mflv_1441|M.gilvum_PYR-GCK MWARHIREGLSQLAESTIADRLA
Mvan_5343|M.vanbaalenii_PYR-1 MWARHIREGLSQLAESTIADRLG
MAB_0562c|M.abscessus_ATCC_199 MWARHIREGLSRLAESTLTEQTG
** *:*:*** *****:::