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M. tuberculosis H37Rv Rv3379c (dxs2)

annotation: 1-deoxy-D-xylulose-5-phosphate synthase
coordinates: 3793257 - 3794867
length: 536

FDTGHQTYPHKLLTGRGKDFATLRQADGLSGYPNRHESPHDWVENSHASVSLAWVDGIAKALALQGQCDR
RVIAVIGDGALTGGVAWEGLNNLGAATRPVIVVLNDNGRSYDPTAGALAAHLEELRVGTPRGPNLFENMG
FTYIGPVDGHNIPDTCAVLRKAAAAARPVVVHAVTSKGRGYPPAEADERDHMHACGVVDIATGLASTPSQ
RSWTDVFEDEIARIADDRSDVVGLTAAMRLPTGLGALSRRYPHRVFDSGIAEQHLLASAAGLAAAGTHPV
VAVYSTFLHRAFDQLLFDIGLHRLPVTLVLDRAGVTGPDGPSHHGLWDLALLACVPGFQIACPRDAPRLR
QQLRTAIATAAPTAVRFPKGAPGEPITAEHTIGGLDVLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLSE
EQIGVTVVDPQWVWPISPALTELAGRHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRTYTLGLPPAYIP
HASRDHILSSHGLTGPAIRIRCKSLLNALHEVPGPEDHPDSGDSY*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3379cdxs2-100% (536)1-deoxy-D-xylulose-5-phosphate synthase
M. tuberculosis H37RvRv2682cdxs1e-14848.57% (558) 1-deoxy-D-xylulose-5-phosphate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3413cdxs20.099.81% (536) 1-deoxy-D-xylulose-5-phosphate synthase
M. gilvum PYR-GCKMflv_3923-1e-14948.25% (572) 1-deoxy-D-xylulose-5-phosphate synthase
M. leprae Br4923MLBr_01038dxs1e-14448.25% (543) 1-deoxy-D-xylulose-5-phosphate synthase
M. abscessus ATCC 19977MAB_2990c-1e-14649.17% (545) 1-deoxy-D-xylulose-5-phosphate synthase
M. marinum MMMAR_0276dxs20.070.04% (534) 1-deoxy-D-xylulose 5-phosphate synthase Dxs2
M. avium 104MAV_3577dxs1e-14748.75% (562) 1-deoxy-D-xylulose-5-phosphate synthase
M. smegmatis MC2 155MSMEG_2776dxs1e-15150.83% (543) 1-deoxy-D-xylulose-5-phosphate synthase
M. thermoresistible (build 8)TH_2209dxs1e-14949.55% (559) 1-deoxy-D-xylulose-5-phosphate synthase
M. ulcerans Agy99MUL_3319dxs11e-14346.95% (558) 1-deoxy-D-xylulose-5-phosphate synthase
M. vanbaalenii PYR-1Mvan_2477-1e-14649.36% (543) 1-deoxy-D-xylulose-5-phosphate synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3923|M.gilvum_PYR-GCK          -----------MLEQIRGPADLQHLSRAQMEDLAREIRDFLIHKVAATGG
Mvan_2477|M.vanbaalenii_PYR-1       -----------MLEQIRGPADLQHLSQAQLEDLAHEIRDFLIHKVAATGG
MSMEG_2776|M.smegmatis_MC2_155      -----------MLEQVRGPADLQHLSQSQLRDLAQEIRQFLIHKVAATGG
TH_2209|M.thermoresistible__bu      -----------MLEQIRGPADLQHLSKAQLRDLADEIRQFLIHKVAATGG
MAV_3577|M.avium_104                -----------MLEQIRGPADLQHLSTHQLRELAAEIREFLIHKVAATGG
MUL_3319|M.ulcerans_Agy99           -----------MLQQIRGPADLQHLSQAQLRELAQEIREFLVHKVAATGG
MLBr_01038|M.leprae_Br4923          -----------MLEQIRRPADLQHLSQQQLRDLAAEIRELLVHKVAATGG
MAB_2990c|M.abscessus_ATCC_199      -----------MLDDIRGPGDLQGLSKRELDLLADEIREFLIHKVAATGG
Rv3379c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3413c|M.bovis_AF2122/97           -----------MITAIGGPCDVQALPESQLPELAVQMRRRLIETVTATGG
MMAR_0276|M.marinum_M               MSITMRADRADLLSLINGPQDVQALPADQLPLLAAQIRRRMIETVASTGG
                                                                                      

Mflv_3923|M.gilvum_PYR-GCK          HLGPNLGVVELTLALHRVFDSPHDPILFDTGHQAYVHKMLTGRSRDFDTL
Mvan_2477|M.vanbaalenii_PYR-1       HLGPNLGVVELTLALHRVFDSPHDPILFDTGHQAYVHKMLTGRCRDFDSL
MSMEG_2776|M.smegmatis_MC2_155      HLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRSEDFDTL
TH_2209|M.thermoresistible__bu      HLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRAADFDTL
MAV_3577|M.avium_104                HLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRAHEFESL
MUL_3319|M.ulcerans_Agy99           HLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQTYVHKMLTGRAQDFESL
MLBr_01038|M.leprae_Br4923          HLGPNLGVVELTLALHRVFDSPHDPIIFDTGHQAYVHKMLTGRCQDFDSL
MAB_2990c|M.abscessus_ATCC_199      HLGPNLGVVELSLALHRVFESPYDPIIFDTGHQAYVHKILTGRAGDFDTL
Rv3379c|M.tuberculosis_H37Rv        --------------------------MFDTGHQTYPHKLLTGRGKDFATL
Mb3413c|M.bovis_AF2122/97           HLGAGLGMVELTIALHRVFTSPHDIVVFDTGHQTYPHKLLTGRGKDFATL
MMAR_0276|M.marinum_M               HLGAGLGTVELIIALHRVFSSPRDIVVFDTGHQTYPHKLLTGRGDQFVTL
                                                              :******:* **:****  :* :*

Mflv_3923|M.gilvum_PYR-GCK          RKKDGLSGYPSRSESEHDWVESSHASSALSYADGLAKAFELNGHRNRHVV
Mvan_2477|M.vanbaalenii_PYR-1       RKKDGLSGYPSSAESEHDWIESSHASSALSYADGLAKAFELSGHRNRHVV
MSMEG_2776|M.smegmatis_MC2_155      RSKDGLSGYPSRSESDHDWVESSHASAALSYADGLAKAFELTGHRNRHVV
TH_2209|M.thermoresistible__bu      RKKGGLSGYPSRAESEHDWVESSHASAALSYADGLAKAFELTGHRNRHVV
MAV_3577|M.avium_104                RKKGGLSGYPSRSESEHDWVESSHASAALSYADGLAKAFELSGHRNRHVV
MUL_3319|M.ulcerans_Agy99           RKKGGLSGYPCRAESEHDWVESSHASAALSYADGLSKAFELSGLRNRHVV
MLBr_01038|M.leprae_Br4923          RKKAGLSGYPSRAESEHDWVESSHASTALSYADGLAKAFELAGNRNRHVV
MAB_2990c|M.abscessus_ATCC_199      RQKDGLSGYPSRAESEHDWVESSHASTALSYADGLAKAFELTGQRRRHVV
Rv3379c|M.tuberculosis_H37Rv        RQADGLSGYPNRHESPHDWVENSHASVSLAWVDGIAKALALQGQCDRRVI
Mb3413c|M.bovis_AF2122/97           RQADGLSGYPNRHESPHDWVENSHASVSLAWVDGIAKALALQGQCDRRVI
MMAR_0276|M.marinum_M               RQPGGLSGYPSRSESHHDWVENSHASVSLAWVDGIAKALALQGRGDRRVV
                                    *.  ******   ** ***:*.**** :*::.**::**: * *   *:*:

Mflv_3923|M.gilvum_PYR-GCK          AVVGDGALTGGMCWEALNNIAASR-RPVVIVVNDNGRSYAPTIGGFAEHL
Mvan_2477|M.vanbaalenii_PYR-1       AVVGDGALTGGMCWEALNNIAASR-RPVVIVVNDNGRSYAPTIGGFAEHL
MSMEG_2776|M.smegmatis_MC2_155      AVVGDGALTGGMCWEALNNIATSR-RPVVIVVNDNGRSYAPTIGGLAEHL
TH_2209|M.thermoresistible__bu      AVVGDGALTGGMCWEAINNIAAAR-RPVVIVVNDNGRSYAPTIGGFAEHL
MAV_3577|M.avium_104                AVVGDGALTGGMCWEALNNIAASG-RPVIIVVNDNGRSYAPTIGGVADHL
MUL_3319|M.ulcerans_Agy99           AVVGDGALTGGMCWEALNNIAASH-RPVVIVVNDNGRSYAPTIGGVADHL
MLBr_01038|M.leprae_Br4923          AVVGDGALTGGMCWEALNNIAATP-RPVVIVVNDNGRSYAPTIGGVADHL
MAB_2990c|M.abscessus_ATCC_199      AVVGDGAMTGGMCWEALNNIAAAEHRRIIIVVNDNGRSYAPTIGGLASHL
Rv3379c|M.tuberculosis_H37Rv        AVIGDGALTGGVAWEGLNNLGAAT-RPVIVVLNDNGRSYDPTAGALAAHL
Mb3413c|M.bovis_AF2122/97           AVIGDGALTGGVAWEGLNNLGAAT-RPVIVVLNDNGRSYDPTAGALAAHL
MMAR_0276|M.marinum_M               SVIGDGALTGGVAWEGLNNLGGAD-RAVIIVLNDNGRSYDPTTGAVATHL
                                    :*:****:***:.**.:**:. :  * :::*:******* ** *..* **

Mflv_3923|M.gilvum_PYR-GCK          AGLRLQPGYERVLEEGRKAVRGVPMIGEFCYQCMHSIKAGIKDALSPQVM
Mvan_2477|M.vanbaalenii_PYR-1       AGLRLQPGYERVLEEGRKAVRGVPMIGEFCYQCMHSIKVGIKDALSPQVM
MSMEG_2776|M.smegmatis_MC2_155      AALRLQPGYERVLEEGRKAVRGVPLIGELCYQCIHSIKAGIKDAIAPQVM
TH_2209|M.thermoresistible__bu      AALRLQPQYENLLEQSRQAVRGIPMIGELCYRAMHSVKVGLKDALAPQEM
MAV_3577|M.avium_104                ATLRLQPAYEQALQRGRDALRALPLVGKFAYRVMHSVKAGIKDSLSPQLL
MUL_3319|M.ulcerans_Agy99           AKLRLQPAYEQVLEKGRDVVRAVPLVGEVCYHFMHSVKAGIKDSLSPQLL
MLBr_01038|M.leprae_Br4923          ATLRLQPAYERLLEKGRDALHSLPLIGQIAYRFMHSVKAGIKDSLSPQLL
MAB_2990c|M.abscessus_ATCC_199      AGLRLTPSYEKVLDESKKLLRGMPVVGPLAYALMHSLKVGVKDAVSPQVM
Rv3379c|M.tuberculosis_H37Rv        EELRVG-------------------------------------TPRGPNL
Mb3413c|M.bovis_AF2122/97           EELRVG-------------------------------------TPRGPNL
MMAR_0276|M.marinum_M               QALRHG-------------------------------------VSSGPNL
                                      **                                             :

Mflv_3923|M.gilvum_PYR-GCK          FTDLGLKYVGPIDGHDESAVEGALRHARAFNAPVVVHVVTRKGMGYAPAE
Mvan_2477|M.vanbaalenii_PYR-1       FTDLGLKYVGPIDGHDEHAVESALRHARAFNAPVVVHVVTRKGMGYAPAE
MSMEG_2776|M.smegmatis_MC2_155      FTDLGIKYVGPIDGHDEHAVESALRHARGFNAPVIVHVVTRKGMGYAPAE
TH_2209|M.thermoresistible__bu      FTDLGLKYVGPIDGHDEHAVEVALRRARGYNAPVVVHVVTRKGMGYGPAE
MAV_3577|M.avium_104                FTDLGLKYVGPVDGHDERAVEAALRHARGFGRPVIVHVVTRKGMGYAPAE
MUL_3319|M.ulcerans_Agy99           FTDLGLKYVGPVDGHDERAVEVALRSARGFGGPVIVHVVTRKGMGYGPAE
MLBr_01038|M.leprae_Br4923          FTDLGLKYVGPVDGHDEHAVEVALRKARGFGGPVIVHVVTRKGMGYPPAE
MAB_2990c|M.abscessus_ATCC_199      FTDLGLKYVGPVDGHDEHAVEDALRRARGYGGPVIVHVITRKGMGYAPAE
Rv3379c|M.tuberculosis_H37Rv        FENMGFTYIGPVDGHNIPDTCAVLRKAAAAARPVVVHAVTSKGRGYPPAE
Mb3413c|M.bovis_AF2122/97           FENMGFTYIGPVDGHNIPDTCAVLRKAAAAARPVVVHAVTSKGRGYPPAE
MMAR_0276|M.marinum_M               FETLGFTYIGPTDGHDVESICSALRQAAALDKPVVVHTVTAKGRGYPPAE
                                    *  :*:.*:** ***:      .** * .   **:**.:* ** ** ***

Mflv_3923|M.gilvum_PYR-GCK          NDVDEQMHACGVIDPETGLATSVPGPGWTAAFSETLIELAAKRRDIVAIT
Mvan_2477|M.vanbaalenii_PYR-1       NDADDQMHACGVIDPETGLATSVPGPGWTSTFSEALIRLAGKRRDIVAIT
MSMEG_2776|M.smegmatis_MC2_155      NDEADQMHACGVIDPETGLPTKASGTSWTSVFSDELISQAAKRRDVVAIT
TH_2209|M.thermoresistible__bu      ADEAEQMHACGVIDVETGKPPKASAPGWTSVFSDALVRIGARRRDVVAIT
MAV_3577|M.avium_104                DDEADQMHSCGVIDPITGQATKVAGPGWTATFSDALIGYARKRRDIVAIT
MUL_3319|M.ulcerans_Agy99           ADVAEQMHSTVPIDPATGQATKLAGPGWTTTFADALIEYAGKRRDIVAIT
MLBr_01038|M.leprae_Br4923          ADQAEQMHTCGVMDPTTGQPTKIAAPDWTAIFSDALIGYAMKRRDIVAIT
MAB_2990c|M.abscessus_ATCC_199      DDEAEQMHSTGIIDPKTGRAIKASAPGWTSVFSDALIDVASEHRNIVAIT
Rv3379c|M.tuberculosis_H37Rv        ADERDHMHACGVVDIATGLASTPSQRSWTDVFEDEIARIADDRSDVVGLT
Mb3413c|M.bovis_AF2122/97           ADERDHMHAYGVVDIATGLASTPSQRSWTDVFEDEIARIADDRSDVVGLT
MMAR_0276|M.marinum_M               ADESDRMHACGVIEVATGRPAKPTAASWTDVFEQELVRIADERTDVVGMT
                                     *  ::**:   ::  ** . . .  .**  * : :   .  : ::*.:*

Mflv_3923|M.gilvum_PYR-GCK          AAMPGPTGLSAFRKRFPDRFFDVGIAEQHAMTSAAGLAMGGMHPVVALYS
Mvan_2477|M.vanbaalenii_PYR-1       AAMPGPTGLSAFRDRFPDRFFDVGIAEQHAMTSAAGLAMGGMHPVVAIYS
MSMEG_2776|M.smegmatis_MC2_155      AAMPGPTGLSAFRDRFPDRFFDVGIAEQHAMTSAAGLAMGGLHPVVAIYS
TH_2209|M.thermoresistible__bu      AAMPGPTGLTAFRERFPDRFFDVGIAEQHAMTSAAGLAMGGLHPVVAVYS
MAV_3577|M.avium_104                AAMPGPTGLTPFGQQFPDRLFDVGIAEQHAMTSAAGLAMGGMHPVVAIYS
MUL_3319|M.ulcerans_Agy99           AAMPGPTGLTAFGQQFPDRLFDVGIAEQHAMTSAAGLAMGGMHPVVAIYS
MLBr_01038|M.leprae_Br4923          AAMPGPTGLTAFGQCFPDRLFDVGIAEQHAMTSAAGLAMGRMHPVVAIYS
MAB_2990c|M.abscessus_ATCC_199      AAMPGPTGLSKFGERFPDRLFDVGIAEQHAVTSAAGLAMGGLHPVVAIYS
Rv3379c|M.tuberculosis_H37Rv        AAMRLPTGLGALSRRYPHRVFDSGIAEQHLLASAAGLAAAGTHPVVAVYS
Mb3413c|M.bovis_AF2122/97           AAMRLPTGLGALSRRYPHRVFDSGIAEQHLLASAAGLAAAGTHPVVAVYS
MMAR_0276|M.marinum_M               AAMRLPAGLGALSRKYPDRVFDSGIAEQHLLACAAGLASAGAHPVVALYS
                                    ***  *:**  :   :*.*.** ****** ::.***** .  *****:**

Mflv_3923|M.gilvum_PYR-GCK          TFLNRAFDQMLMDVALHKLPVTMVLDRSGITGPDGASHNGMWDLSILGIV
Mvan_2477|M.vanbaalenii_PYR-1       TFLNRAFDQMLMDVALHKLPVTVVLDRSGVTGPDGASHNGMWDLSILGIV
MSMEG_2776|M.smegmatis_MC2_155      TFLNRAFDQLMMDVALHKLPVTMVLDRAGITGPDGASHNGMWDLSILGII
TH_2209|M.thermoresistible__bu      TFLNRAFDQMLMDVALHKLPVTIVLDRSGITGPDGASHNGMWDLSILGIV
MAV_3577|M.avium_104                TFLNRAFDQIMMDVALHRLPVTMVLDRAGITGSDGASHNGMWDLSILGVV
MUL_3319|M.ulcerans_Agy99           TFLNRAFDQIMMDVALHQLPVTMVLDRAGITGSDGPSHNGMWDLSMLGII
MLBr_01038|M.leprae_Br4923          TFLNRAFDQIMMDVALHKLPVTMVIDRAGITGSDGPSHNGMWDLSMLGIV
MAB_2990c|M.abscessus_ATCC_199      TFLNRAFDQVMMDVALHRLPVTFVLDRAGITGSDGASHNGMWDLSILNVV
Rv3379c|M.tuberculosis_H37Rv        TFLHRAFDQLLFDIGLHRLPVTLVLDRAGVTGPDGPSHHGLWDLALLACV
Mb3413c|M.bovis_AF2122/97           TFLHRAFDQLLFDIGLHRLPVTLVLDRAGVTGPDGPSHHGLWDLALLACV
MMAR_0276|M.marinum_M               TFLHRAFDQLLFDVGLHQLPVTLVLDRAGITGPDGASHHGMWDLALLTNV
                                    ***:*****:::*:.**:****.*:**:*:**.**.**:*:***::*  :

Mflv_3923|M.gilvum_PYR-GCK          PGMRVAAPRDGARLREELAEAVEVKDGPTAVRFPKGDVGEDIPAIERR--
Mvan_2477|M.vanbaalenii_PYR-1       PGMRVAAPRDGARLREELGEALDVSDGPTAIRFPKGDVGEDIPAIERR--
MSMEG_2776|M.smegmatis_MC2_155      PGIRVAAPRDGARLRAELGEALAVNDGPTAIRFPKGDVGEDIPAVQRR--
TH_2209|M.thermoresistible__bu      PGMRVAAPRDGLRLREQLGEALDVKDGPTAIRFPKGDIGEDIPAVERR--
MAV_3577|M.avium_104                PGMRVAAPRDAARLREELGEALDVDDGPTALRFPKGDVGEDIPAIERRGS
MUL_3319|M.ulcerans_Agy99           PGIRVAAPRDATRLREELGEALDVDDGPTALRFPKGDVGEDIPALERR--
MLBr_01038|M.leprae_Br4923          PGMRVAAPRDAIRLREELGEALDVDDGPTAIRFPKGDVCEDIPALKRR--
MAB_2990c|M.abscessus_ATCC_199      PGMRVAAPRDASRLREELTEALAVDDGPTALRFPKGEVGEDIPAIERR--
Rv3379c|M.tuberculosis_H37Rv        PGFQIACPRDAPRLRQQLRTAIAT-AAPTAVRFPKGAPGEPITAEHTI--
Mb3413c|M.bovis_AF2122/97           PGFQIACPRDAPRLRQQLRTAIAT-AAPTAVRFPKGAPGEPITAEHTI--
MMAR_0276|M.marinum_M               PGLRVACPRDAVRLRQQLRVAIDD-TSPNALRYPKGVPDNDIPAVGQI--
                                    **:::*.***. *** :*  *:    .*.*:*:***   : *.*      

Mflv_3923|M.gilvum_PYR-GCK          --DGVDVLAVPADGLSDDVLIIAVGAFAAMSVAVAERLRDQGIGVTVVDP
Mvan_2477|M.vanbaalenii_PYR-1       --GDVDVLAVPADGMSEDVLLVAVGPFAAMALAVADRLRNQGIGVTVVDP
MSMEG_2776|M.smegmatis_MC2_155      --DGVDVLAVPATGLTHDVLLVAVGSFAKMALAVAELLRSQGIGVTVVDP
TH_2209|M.thermoresistible__bu      --DGVDVLSLPDDGLSADVLLVTVGPFAAMGLAAAERLRNQGIGVTVIDP
MAV_3577|M.avium_104                GLSGVDVLALPASGCNHDVLLIGVGAFAPMALAVARRLADQGIGVTVVDP
MUL_3319|M.ulcerans_Agy99           --DGMDVLAVPASGLNHDVLLIAVGALASMALAVAKRLHNQGIGVTVIDP
MLBr_01038|M.leprae_Br4923          --SGVDVLAVPATGLAQDVLLVGVGVFASMALAVAKRLHNQGIGVTVIDP
MAB_2990c|M.abscessus_ATCC_199      --DGVDILARPASGLHADVLLVAVGSFASTALATADRLGKQGIGVTVVDP
Rv3379c|M.tuberculosis_H37Rv        --GGLDVLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLSEEQIGVTVVDP
Mb3413c|M.bovis_AF2122/97           --GGLDVLHTPPPHWRPDVLLVAVGAMSRPCMDAARCLSEEQIGVTVVDP
MMAR_0276|M.marinum_M               --DGVDVLFAGGKPDR-DVLLIAVGVMAHPCVDAAERLAAAGVGVSVVDP
                                      ..:*:*         ***:: ** ::   : .*  *    :**:*:**

Mflv_3923|M.gilvum_PYR-GCK          RWVLPVPAAINTLAAAHKLVVTVEDNGGHGGVGSAVSAALRRAEIDVPCR
Mvan_2477|M.vanbaalenii_PYR-1       RWVLPVPEEIATLATRHKLVVTLEDNGGHGGVGSAVSGALRHKEIDVPCR
MSMEG_2776|M.smegmatis_MC2_155      RWVLPVPEALADLARDHKLVVTVEDNGLHGGIGSSVSAALRHAEIDVPCR
TH_2209|M.thermoresistible__bu      RWVLPVPQVITELARDHKLVVTVEDNGGHGGVGSAVSAALRAAEVDVPCR
MAV_3577|M.avium_104                RWVLPVSDSILELAARHKLVVTCEDNGVNGGVGSAVSAALRRAELDVPCR
MUL_3319|M.ulcerans_Agy99           RWVLPVADGIGDLAVAHKLVVTLEDNGVNGGVGSAVSAALRRAEIGVHCR
MLBr_01038|M.leprae_Br4923          RWVLPVCDGVLELAHTHKLIVTLEDNGVNGGVGAAVSTALRQVEIDTPCR
MAB_2990c|M.abscessus_ATCC_199      RWVLPVPPHVVELAGQHRLVVTLEDSGVHGGAGSAVTAAMQDADVDIPSR
Rv3379c|M.tuberculosis_H37Rv        QWVWPISPALTELAGRHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRTY
Mb3413c|M.bovis_AF2122/97           QWVWPISPALTELAGRHRITVCVEDAIADVGIGAHLSHHIGRTHPRTRTY
MMAR_0276|M.marinum_M               GWVWPLNPALTELARQHRITVCVEDGVADAGIGSRLNHQIGWLSPRTRTL
                                     ** *:   :  **  *:: *  **   . * *: :.  :          

Mflv_3923|M.gilvum_PYR-GCK          DAALPQAFFDHASRGEVLAEVGLTERTIARQITGWVAALG-ATAGDR--Q
Mvan_2477|M.vanbaalenii_PYR-1       DAALPQEFFAHASRGEVLESVGLTERNIARQITGWVAALG-ASTGDR--E
MSMEG_2776|M.smegmatis_MC2_155      DVGVPQQFQDHASRGEVLAEVGLTDRHIARQITGWVAAIGTRSAAED--E
TH_2209|M.thermoresistible__bu      DLALPQQFFDHASRSEVLAEVGLTEQNVARRITGWVAALSPEMAEEQS-Q
MAV_3577|M.avium_104                DVGLPQRFYEHASRGELLADLALTDQDIARRITGWVAALGSGVAEAE---
MUL_3319|M.ulcerans_Agy99           DVGLPQQFFEHASRGELLADLRLTDQDVARRVTGWVAALGACVSEAE---
MLBr_01038|M.leprae_Br4923          DVGLPQEFYDHASRSEVLADLGLTDQDVARRITGWVVAFGHCGSGDD---
MAB_2990c|M.abscessus_ATCC_199      DIGVPQQFLEHASRGQVLEELGLTDQHIARKITGWVAAMSREIGDSTVNP
Rv3379c|M.tuberculosis_H37Rv        TLGLPPAYIPHASRDHILSSHGLTGPAIRIRCKSLLNALHEVPGPEDHPD
Mb3413c|M.bovis_AF2122/97           TLGLPPAYIPHASRDHILSSHGLTGPAIRIRCKSLLNALHEVPGPEDHPD
MMAR_0276|M.marinum_M               VLGLPRDYIAHAGRDQILTECGLSGSAISAACQSALAA--DSPGSHDRSE
                                      .:*  :  **.*..:* .  *:   :     . : *            

Mflv_3923|M.gilvum_PYR-GCK          VSESVD-------
Mvan_2477|M.vanbaalenii_PYR-1       VSEHVD-------
MSMEG_2776|M.smegmatis_MC2_155      VGQTLD-------
TH_2209|M.thermoresistible__bu      ISERLD-------
MAV_3577|M.avium_104                IREHLD-------
MUL_3319|M.ulcerans_Agy99           IKEHLD-------
MLBr_01038|M.leprae_Br4923          AGQYGPRSSQTM-
MAB_2990c|M.abscessus_ATCC_199      AAQQVD-------
Rv3379c|M.tuberculosis_H37Rv        SGDSY--------
Mb3413c|M.bovis_AF2122/97           SGDSY--------
MMAR_0276|M.marinum_M               PLDPLAPSPLETP
                                      :