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M. tuberculosis H37Rv Rv3336c (trpS)

annotation: tryptophanyl-tRNA synthetase
coordinates: 3722621 - 3723631
length: 336

STPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQ
YLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAAD
VLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAG
LINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDT
AEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3336ctrpS-100% (336)tryptophanyl-tRNA synthetase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3369ctrpS0.0100.00% (336) tryptophanyl-tRNA synthetase
M. gilvum PYR-GCKMflv_4871-1e-15280.37% (326) tryptophanyl-tRNA synthetase
M. leprae Br4923MLBr_00686trpS1e-16283.78% (339) tryptophanyl-tRNA synthetase
M. abscessus ATCC 19977MAB_3683c-1e-13668.45% (336) tryptophanyl-tRNA synthetase
M. marinum MMMAR_1188trpS1e-16987.76% (335) tryptophanyl-tRNA synthetase TrpS
M. avium 104MAV_4310trpS1e-16586.14% (339) tryptophanyl-tRNA synthetase
M. smegmatis MC2 155MSMEG_1657trpS1e-15479.52% (332) tryptophanyl-tRNA synthetase
M. thermoresistible (build 8)TH_1974trpS1e-15882.21% (326) PROBABLE TRYPTOPHANYL-TRNA SYNTHETASE TRPS (TRYPTOPHAN--TRNA
M. ulcerans Agy99MUL_1441trpS1e-17188.06% (335) tryptophanyl-tRNA synthetase
M. vanbaalenii PYR-1Mvan_1560-1e-15380.67% (326) tryptophanyl-tRNA synthetase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4871|M.gilvum_PYR-GCK          ----MSNTT-RPVVFSGAQPTSDSLHLGNALGAVSQWVSLQDGY----DA
Mvan_1560|M.vanbaalenii_PYR-1       MNTTMSNTP-RPVVFSGAQPTSDSLHLGNALGAVAQWVGLQEGN----DA
MSMEG_1657|M.smegmatis_MC2_155      ----MSSGS-KRVVFSGAQPTSDSLHLGNALGAVTHWAQLQDDY----DA
TH_1974|M.thermoresistible__bu      --MNTSVRT-RPVVFSGAQPTSDSLHLGNALGAIAQWVGLQDDH----DA
Rv3336c|M.tuberculosis_H37Rv        ----MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDH----DA
Mb3369c|M.bovis_AF2122/97           ----MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDH----DA
MMAR_1188|M.marinum_M               ----MSTPTGSRRIFSGVQPTSDSLHLGNALGAVTQWVALQDDH----DA
MUL_1441|M.ulcerans_Agy99           ----MSTPTGSRRIFSGVQPTSDSLHLGNALGAVTQWVALQDDH----DA
MLBr_00686|M.leprae_Br4923          ----MSTATGFSRIFSGVQPTSDSLHLGNALGAITQWVALQYDHPDEYEA
MAV_4310|M.avium_104                ----MSTATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDA
MAB_3683c|M.abscessus_ATCC_199      ---MTAETAARGRLFSGIQPTADSLHLGNVLGAVQQWVRLQHEY----EA
                                         :  .    :*** ***:*******.***: :*. **       :*

Mflv_4871|M.gilvum_PYR-GCK          YFCVVDLHAITVAQDPATLRRRTLVTAAQYLALGIDPSRATVFVQSHVPS
Mvan_1560|M.vanbaalenii_PYR-1       YFCVVDLHAITVSQDPETLRKRTLATAAQYLALGVDPDRATVFVQSHVPA
MSMEG_1657|M.smegmatis_MC2_155      FFCVVDLHAITVPQDPETLRRRTLVTAAQYLALGIDPARSTVFVQSHVPT
TH_1974|M.thermoresistible__bu      FFCVVDLHAITVPQDPETLRRRTLVTAAQYLALGIDPARSTVFVQSHVAA
Rv3336c|M.tuberculosis_H37Rv        FFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPA
Mb3369c|M.bovis_AF2122/97           FFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPA
MMAR_1188|M.marinum_M               FFCVVDLHAITLPQDPEALRRRTLVTAAQYLALGIDPARATIFVQSHVPA
MUL_1441|M.ulcerans_Agy99           FFCVVDLHAITLPQDPEALRRRTLVTAAQYLALGIDPARATIFVQSHVPA
MLBr_00686|M.leprae_Br4923          FFCVVDLHAITIAQDPETLWRRTLVTAAQYLALGIDPGRAVVFVQSHVPA
MAV_4310|M.avium_104                FFCVVDLHAITIAQDPAALRRRTLVTAAQYLALGIDPARSTVFVQSHVPA
MAB_3683c|M.abscessus_ATCC_199      LFCVVDLHAITVAQDPEELRRRTRAVVAQYVALGVDPAKSAIFVQSHVPA
                                     **********:.***  * :**  ..***:***:** ::.:****:*.:

Mflv_4871|M.gilvum_PYR-GCK          HAELAWVLGCFTGFGQASRMTQFKDKSQKQGAEATTVGLFTYPVLMAADV
Mvan_1560|M.vanbaalenii_PYR-1       HAELAWVLGCFTGFGQASRMTQFKDKSQKQGADSTTVGLFTYPVLMAADV
MSMEG_1657|M.smegmatis_MC2_155      HSQLAWVLGCFTGFGQASRMTQFKDKSQKQGADATTVGLFTYPVLMAADV
TH_1974|M.thermoresistible__bu      HAELAWVLGCFTGFGQASRMTQFKDKAQKQGTEGTTVGLFTYPVLMAADV
Rv3336c|M.tuberculosis_H37Rv        HTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADV
Mb3369c|M.bovis_AF2122/97           HTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADV
MMAR_1188|M.marinum_M               HSQLAWVLGCFTGFGQASRMTQFKDKSTRQGADSATVGLFTYPVLQAADV
MUL_1441|M.ulcerans_Agy99           HSQLAWVLGCFTGFGQASRMTQFKDKSTRQGADSATVGLFTYPVLQAADV
MLBr_00686|M.leprae_Br4923          HTQLAWVLGCFTGFGQASRMTQFKDKALRQGADSTTVGLFTYPVLQAADV
MAV_4310|M.avium_104                HTQLAWVLGCFTGFGQASRMTQFKDKSLRQGADSTTVGLFTYPVLQAADV
MAB_3683c|M.abscessus_ATCC_199      HAELAWVLGCLTGYGEAARMTQFKDKSAKQGNDATTVGLFTYPVLMAADI
                                    *::*******:**:*:*:********: :** :.:********** ***:

Mflv_4871|M.gilvum_PYR-GCK          LLYDTELVPVGEDQRQHLELARDVAQRINARFPDTFVVPEAMIPKATAKI
Mvan_1560|M.vanbaalenii_PYR-1       LLYDTGLVPVGEDQRQHLELARDLAQRINARFPGTFVVPEAMIPKATAKI
MSMEG_1657|M.smegmatis_MC2_155      LLYDTHVVPVGEDQRQHLELARDLAQRFNARFPDTFVVPEPMIPKATAKI
TH_1974|M.thermoresistible__bu      LLYDTDLVPVGEDQRQHLELARDVAQRFNSRFPDTFVIPEAMIPRTAAKI
Rv3336c|M.tuberculosis_H37Rv        LAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKI
Mb3369c|M.bovis_AF2122/97           LAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKI
MMAR_1188|M.marinum_M               LAYDAELVPVGEDQRQHLELARDIAQRFNGRFPDTFVVPDVLIPKITAKI
MUL_1441|M.ulcerans_Agy99           LAYDAELVPVGEDQRQHLELARDIAQRFNGRFPDTFVVPDVLIPKITAKI
MLBr_00686|M.leprae_Br4923          LAYDTDLVPVGEDQRQHLELARDLAQRFNSRFPDTFVVPDMFIPKMAAKI
MAV_4310|M.avium_104                LAYDTGLVPVGEDQRQHLELARDVAQRFNARFPDTFVVPEMLIPKVTAKI
MAB_3683c|M.abscessus_ATCC_199      LLYQTNVVPVGDDQRQHLELTRDVAQRFNGRYGQTFVLPETFVPKNAARI
                                    * *:: :****:********:**:***:*.*:  *:*:*: ::*: :*:*

Mflv_4871|M.gilvum_PYR-GCK          FDLQDPTAKMSKSAESDAGLISLLDDPAKTAKKIRSAVTDSEREIRFDRE
Mvan_1560|M.vanbaalenii_PYR-1       YDLQDPTAKMSKSADSDAGLISLLDDPAKTAKKIRSAVTDSEREIRFDRD
MSMEG_1657|M.smegmatis_MC2_155      YDLQDPTAKMSKSAATDAGLISLLDDPKATAKKIRSAVTDSEREIRFDPE
TH_1974|M.thermoresistible__bu      YDLQDPTAKMSKSAGSDAGLIALLDDPKVTAKKIRSAVTDSEREIRYDPE
Rv3336c|M.tuberculosis_H37Rv        YDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPD
Mb3369c|M.bovis_AF2122/97           YDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPD
MMAR_1188|M.marinum_M               YDLQDPTSKMSKSASTDAGLISLLDAPAVSAKKIRSAVTDSEREIRYDPE
MUL_1441|M.ulcerans_Agy99           YDLQDPTSKMSKSASTDAGLISLLDAPAVSAKKIRSAVTDSEREIRYDPE
MLBr_00686|M.leprae_Br4923          YDLADPTSKMSKSASSDAGLINLLDDPALSVKKIRAAVTDSEREIRYDPE
MAV_4310|M.avium_104                YDLADPTSKMSKSASTDAGLVNLLDDPALSAKKIRSAVTDSEREIRFDTD
MAB_3683c|M.abscessus_ATCC_199      YDLQDPTVKMSKSASTPAGLINLLDEPAVSAKKVKSAQTDSDREIRFDRD
                                    :** *** ****** : ***: *** *  :.**:::* ***:*:**:* :

Mflv_4871|M.gilvum_PYR-GCK          AKPGVSNLLTIQSAVTGTDIDKLVEGYAGRGYGDLKKETAEAVVEFVTPI
Mvan_1560|M.vanbaalenii_PYR-1       AKPGVSNLLTIQSAVTGVDVDKLVEGYAGRGYGDLKKETAEAVVEFVTPI
MSMEG_1657|M.smegmatis_MC2_155      AKPGISNLLTIQSAVTGTTVDKLVESYAGRGYGDLKKDTAEAVVEFVTPI
TH_1974|M.thermoresistible__bu      AKPGVSNLLTIQSAVTGTDIDTLVARYAGRGYGDLKKDTAEAVVEFVTPI
Rv3336c|M.tuberculosis_H37Rv        VKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPI
Mb3369c|M.bovis_AF2122/97           VKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPI
MMAR_1188|M.marinum_M               AKPGVSNLLSIQSAVSRVSIDTLVDGYAGRGYGDLKKDTAEAVVAYVSPI
MUL_1441|M.ulcerans_Agy99           AKPGVSNLLSIQSAVSGVSIDTLVDGYAGRGYGDLKKDTAEAVVAYVSPI
MLBr_00686|M.leprae_Br4923          VKPGVSNLLNIQSAVTGVDVDTLVQRYVGHGYGDLKKDTAEAVVEFVSPI
MAV_4310|M.avium_104                AKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPI
MAB_3683c|M.abscessus_ATCC_199      AKPGVSNLLSIQSALTGADIETLVDGYAGRGYGDLKKDTAEALIEFVTPV
                                    .***:****.****:: . :: **  *.*:*******:**:*:: :*.*:

Mflv_4871|M.gilvum_PYR-GCK          KSTVDDLLGDPAELEAVLARGAERAREVSGQTLRRVYDRLGFLASR-
Mvan_1560|M.vanbaalenii_PYR-1       KARVDELLGDPAELEGVLARGAQRAREVSGVTLRRVYDRLGFLASR-
MSMEG_1657|M.smegmatis_MC2_155      KTRVDDLLSDRAELESVLAAGARRATEVSAKTLQRVYDRIGFLPQPS
TH_1974|M.thermoresistible__bu      KTRVDELLADPAELEGILAAGAERAREVSATTLKRVYDRLGFLPPRS
Rv3336c|M.tuberculosis_H37Rv        QARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL---
Mb3369c|M.bovis_AF2122/97           QARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL---
MMAR_1188|M.marinum_M               KARVDELTADLSELETVLAAGAERAHDIASKTVQRVYDRLGFLPQRG
MUL_1441|M.ulcerans_Agy99           KARVDELTADLSELETVLAAGAERAHDIASKTVQRVYDRLGFLPQRG
MLBr_00686|M.leprae_Br4923          KDRVDELMADLTELEVVLAVGAQRAQDVAGKTMQRVYDRLGFLPQRG
MAV_4310|M.avium_104                KARVDELMADPAELEAVLAAGAQRAQDVAGKTVERVYDRLGFLPRRG
MAB_3683c|M.abscessus_ATCC_199      RDRTNELLSDTAALDDILASGAARARELAEKTLTEVYDRIGFVRPAR
                                    :  .::* .* : *: :** ** ** :::  *: .****:**: