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M. tuberculosis H37Rv Rv3323c (moaX)

annotation: PROBABLE MOAD-MOAE FUSION PROTEIN MOAX
coordinates: 3709049 - 3709714
length: 221

ITVNVLYFGAVREACKVAHEKISLESGTTVDGLVDQLQIDYPPLADFRKRVRMAVNESIAPASTILDDGD
TVAFIPQVAGGSDVYCRLTDEPLSVDEVLNAISGPSQGGAVIFVGTVRNNNNGHEVTKLYYEAYPAMVHR
TLMDIIEECERQADGVRVAVAHRTGELRIGDAAVVIGASAPHRAAAFDAARMCIERLKQDVPIWKKEFAL
DGVEWVANRP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3323cmoaX-100% (221)PROBABLE MOAD-MOAE FUSION PROTEIN MOAX
M. tuberculosis H37RvRv3119moaE11e-5976.22% (143) molybdenum cofactor biosynthesis protein E
M. tuberculosis H37RvRv3112moaD19e-2465.06% (83) molybdenum cofactor biosynthesis protein D

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3352cmoaX1e-125100.00% (221) MOAD-MOAE fusion protein MOAX
M. gilvum PYR-GCKMflv_1702-2e-2441.48% (135) molybdopterin biosynthesis MoaE
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0866-4e-2139.10% (133) molybdopterin-converting factor subunit 2 (MoaE)
M. marinum MMMAR_4666moaE22e-2341.35% (133) molybdenum cofactor biosynthesis protein E2 MoaE2
M. avium 104MAV_0995moaE4e-2036.09% (133) molybdopterin converting factor, subunit 2
M. smegmatis MC2 155MSMEG_5701moaE8e-2440.74% (135) molybdopterin converting factor, subunit 2
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0284moaE21e-2341.35% (133) molybdenum cofactor biosynthesis protein E2 MoaE2
M. vanbaalenii PYR-1Mvan_5050-5e-2339.69% (131) molybdopterin biosynthesis MoaE

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4666|M.marinum_M               --------------------------------------------------
MUL_0284|M.ulcerans_Agy99           --------------------------------------------------
MAV_0995|M.avium_104                --------------------------------------------------
MAB_0866|M.abscessus_ATCC_1997      --------------------------------------------------
Mflv_1702|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5050|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5701|M.smegmatis_MC2_155      --------------------------------------------------
Rv3323c|M.tuberculosis_H37Rv        MITVNVLYFGAVREACKVAHEKISLESGTTVDGLVDQLQIDYPPLADFRK
Mb3352c|M.bovis_AF2122/97           MITVNVLYFGAVREACKVAHEKISLESGTTVDGLVDQLQIDYPPLADFRK
                                                                                      

MMAR_4666|M.marinum_M               ------------------------------MTQVVRALLTDQPISLAEHE
MUL_0284|M.ulcerans_Agy99           ------------------------------MTQVVRALLTDQPISLAEHE
MAV_0995|M.avium_104                ------------------------------MTLVVRAVVTEHPIVLAEHE
MAB_0866|M.abscessus_ATCC_1997      -----------------------------MSTAVTRALLTAESISLIEHE
Mflv_1702|M.gilvum_PYR-GCK          ------------------------------MTIVVRAALTDQLIDTTEHE
Mvan_5050|M.vanbaalenii_PYR-1       ------------------------------MTAVLRAALTEQPIGTIEHE
MSMEG_5701|M.smegmatis_MC2_155      -----------------------------MSAEIVRVELTEDPISLTEYE
Rv3323c|M.tuberculosis_H37Rv        RVRMAVNESIAPASTILDDGDTVAFIPQVAGGSDVYCRLTDEPLSVDEVL
Mb3352c|M.bovis_AF2122/97           RVRMAVNESIAPASTILDDGDTVAFIPQVAGGSDVYCRLTDEPLSVDEVL
                                                                          :* . :   *  

MMAR_4666|M.marinum_M               ELVGRPSAGAVVGFVGVVRNHDGGREVLRLEYSAHP-SAGQVLAEVVADV
MUL_0284|M.ulcerans_Agy99           ELVGRPSAGAVVGFVGVVRNHDGGREVLRLEYSAHP-SAGQVLAEVVADV
MAV_0995|M.avium_104                ELVGHQSAGAVVGFVGMIRDHDGGRRVVRLEYSAHP-SAGEVMAEVVAEV
MAB_0866|M.abscessus_ATCC_1997      RLVDHESAGATVGFVGNVRDHDGGKTVLRLEYSAHP-SAQQVLTDVVRRI
Mflv_1702|M.gilvum_PYR-GCK          NLVAHESAGAVVTFAGVVRDHDGGRGVTRLEYSSHP-TAEQTLADVAAEI
Mvan_5050|M.vanbaalenii_PYR-1       ELVAHEAAGAVVTFAGVVRDHDGGRTVTRLEYSAHP-TAEQTLAEVAAEV
MSMEG_5701|M.smegmatis_MC2_155      ALVAHEAAGAVVGFAGVVRDHDGGRSVLRLEYSAHP-TAQRTLEEVAEEI
Rv3323c|M.tuberculosis_H37Rv        NAISGPSQGGAVIFVGTVRNNNNGHEVTKLYYEAYPAMVHRTLMDIIEEC
Mb3352c|M.bovis_AF2122/97           NAISGPSQGGAVIFVGTVRNNNNGHEVTKLYYEAYPAMVHRTLMDIIEEC
                                      :   : *..* *.* :*:::.*: * :* *.::*  . ..: ::    

MMAR_4666|M.marinum_M               AQHAAGVRAVAASHRIGVLHVGDAALVAAVAADHREAAFTTCAKLVDTIK
MUL_0284|M.ulcerans_Agy99           AQHAAGVRAVAASHRIGVLHVGDAALVAAVAADHREAAFTTCAKLVDTIK
MAV_0995|M.avium_104                AERSCGVRAVAASHRIGVLSIGEAALVAAVAADHRQAAFDTCAQLVDTVK
MAB_0866|M.abscessus_ATCC_1997      AEEADGVRAVAVSHRIGALMVGEAAFVVAVSADHRRQAFATCQRLVDDVK
Mflv_1702|M.gilvum_PYR-GCK          AAESHGVRAIAVSHRVGTLRIGDAALVAAVAADHRGAAFETCARLVDRVK
Mvan_5050|M.vanbaalenii_PYR-1       AAESRGVRAIAVSHRVGTLHIGDAALVAAVAADHRGAAFETCARLVDRVK
MSMEG_5701|M.smegmatis_MC2_155      AAQSDGVRAIAVSHRIGPLKIGDAALVAAVAADHRRAAFETCARLVDVVK
Rv3323c|M.tuberculosis_H37Rv        ERQADGVR-VAVAHRTGELRIGDAAVVIGASAPHRAAAFDAARMCIERLK
Mb3352c|M.bovis_AF2122/97           ERQADGVR-VAVAHRTGELRIGDAAVVIGASAPHRAAAFDAARMCIERLK
                                      .: *** :*.:** * * :*:**.* ..:* **  ** :.   :: :*

MMAR_4666|M.marinum_M               ARLPVWKHQFFGDGSEEWVGSA-
MUL_0284|M.ulcerans_Agy99           ARLPVWKHQFFGDGSEEWVGSA-
MAV_0995|M.avium_104                ARLPVWKHQFFADGTDEWVGSA-
MAB_0866|M.abscessus_ATCC_1997      AALPVWKHQFFANGTDEWVGSA-
Mflv_1702|M.gilvum_PYR-GCK          ERLPVWKHQFFTDGSDEWVNSA-
Mvan_5050|M.vanbaalenii_PYR-1       ERLPVWKHQFFADGSDEWVNSA-
MSMEG_5701|M.smegmatis_MC2_155      ERLPVWKHQHFADGTDEWVNSA-
Rv3323c|M.tuberculosis_H37Rv        QDVPIWKKEFALDG-VEWVANRP
Mb3352c|M.bovis_AF2122/97           QDVPIWKKEFALDG-VEWVANRP
                                      :*:**::.  :*  *** .