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M. tuberculosis H37Rv Rv3119 (moaE1)

annotation: PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN E MOAE1 (MOLYBDOPTERIN CONVERTING FACTOR LARGE SUBUNIT) (MOLYBDOPTERIN
coordinates: 3485132 - 3485575
length: 147

MANVVAEGAYPYCRLTDQPLSVDEVLAAVSGPEQGGIVIFVGNVRDHNAGHDVTRLFYEAYPPMVIRTLM
SIIGRCEDKAEGVRVAVAHRTGELQIGDAAVVIGASAPHRAEAFDAARMCIELLKQEVPIWKKEFSSTGA
EWVGDRP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3119moaE1-100% (147)PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN E MOAE1 (MOLYBDOPTERIN CONVERTING FACTOR LARGE SUBUNIT) (MOLYBDOPTERIN
M. tuberculosis H37RvRv3323cmoaX7e-6076.22% (143) MOAD-MOAE fusion protein MOAX
M. tuberculosis H37RvRv0866moaE24e-2240.91% (132) molybdenum cofactor biosynthesis protein E2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3352cmoaX7e-6076.22% (143) MOAD-MOAE fusion protein MOAX
M. gilvum PYR-GCKMflv_1702-7e-2239.69% (131) molybdopterin biosynthesis MoaE
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0866-1e-2241.67% (132) molybdopterin-converting factor subunit 2 (MoaE)
M. marinum MMMAR_4666moaE28e-2341.67% (132) molybdenum cofactor biosynthesis protein E2 MoaE2
M. avium 104MAV_0995moaE2e-2037.12% (132) molybdopterin converting factor, subunit 2
M. smegmatis MC2 155MSMEG_5701moaE3e-2240.46% (131) molybdopterin converting factor, subunit 2
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0284moaE25e-2341.67% (132) molybdenum cofactor biosynthesis protein E2 MoaE2
M. vanbaalenii PYR-1Mvan_5050-2e-2240.46% (131) molybdopterin biosynthesis MoaE

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4666|M.marinum_M               --------------------------------------------------
MUL_0284|M.ulcerans_Agy99           --------------------------------------------------
MAV_0995|M.avium_104                --------------------------------------------------
Mflv_1702|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5050|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5701|M.smegmatis_MC2_155      --------------------------------------------------
MAB_0866|M.abscessus_ATCC_1997      --------------------------------------------------
Rv3119|M.tuberculosis_H37Rv         --------------------------------------------------
Mb3352c|M.bovis_AF2122/97           MITVNVLYFGAVREACKVAHEKISLESGTTVDGLVDQLQIDYPPLADFRK
                                                                                      

MMAR_4666|M.marinum_M               ------------------------------MTQVVRALLTDQPISLAEHE
MUL_0284|M.ulcerans_Agy99           ------------------------------MTQVVRALLTDQPISLAEHE
MAV_0995|M.avium_104                ------------------------------MTLVVRAVVTEHPIVLAEHE
Mflv_1702|M.gilvum_PYR-GCK          ------------------------------MTIVVRAALTDQLIDTTEHE
Mvan_5050|M.vanbaalenii_PYR-1       ------------------------------MTAVLRAALTEQPIGTIEHE
MSMEG_5701|M.smegmatis_MC2_155      -----------------------------MSAEIVRVELTEDPISLTEYE
MAB_0866|M.abscessus_ATCC_1997      -----------------------------MSTAVTRALLTAESISLIEHE
Rv3119|M.tuberculosis_H37Rv         ---MAN---------------------VVAEGAYPYCRLTDQPLSVDEVL
Mb3352c|M.bovis_AF2122/97           RVRMAVNESIAPASTILDDGDTVAFIPQVAGGSDVYCRLTDEPLSVDEVL
                                                                          :* . :   *  

MMAR_4666|M.marinum_M               ELVGRPSAGAVVGFVGVVRNHDGGREVLRLEYSAHP-SAGQVLAEVVADV
MUL_0284|M.ulcerans_Agy99           ELVGRPSAGAVVGFVGVVRNHDGGREVLRLEYSAHP-SAGQVLAEVVADV
MAV_0995|M.avium_104                ELVGHQSAGAVVGFVGMIRDHDGGRRVVRLEYSAHP-SAGEVMAEVVAEV
Mflv_1702|M.gilvum_PYR-GCK          NLVAHESAGAVVTFAGVVRDHDGGRGVTRLEYSSHP-TAEQTLADVAAEI
Mvan_5050|M.vanbaalenii_PYR-1       ELVAHEAAGAVVTFAGVVRDHDGGRTVTRLEYSAHP-TAEQTLAEVAAEV
MSMEG_5701|M.smegmatis_MC2_155      ALVAHEAAGAVVGFAGVVRDHDGGRSVLRLEYSAHP-TAQRTLEEVAEEI
MAB_0866|M.abscessus_ATCC_1997      RLVDHESAGATVGFVGNVRDHDGGKTVLRLEYSAHP-SAQQVLTDVVRRI
Rv3119|M.tuberculosis_H37Rv         AAVSGPEQGGIVIFVGNVRDHNAGHDVTRLFYEAYPPMVIRTLMSIIGRC
Mb3352c|M.bovis_AF2122/97           NAISGPSQGGAVIFVGTVRNNNNGHEVTKLYYEAYPAMVHRTLMDIIEEC
                                      :     *. * *.* :*::: *: * :* *.::*  . ..: .:    

MMAR_4666|M.marinum_M               AQHAAGVRAVAASHRIGVLHVGDAALVAAVAADHREAAFTTCAKLVDTIK
MUL_0284|M.ulcerans_Agy99           AQHAAGVRAVAASHRIGVLHVGDAALVAAVAADHREAAFTTCAKLVDTIK
MAV_0995|M.avium_104                AERSCGVRAVAASHRIGVLSIGEAALVAAVAADHRQAAFDTCAQLVDTVK
Mflv_1702|M.gilvum_PYR-GCK          AAESHGVRAIAVSHRVGTLRIGDAALVAAVAADHRGAAFETCARLVDRVK
Mvan_5050|M.vanbaalenii_PYR-1       AAESRGVRAIAVSHRVGTLHIGDAALVAAVAADHRGAAFETCARLVDRVK
MSMEG_5701|M.smegmatis_MC2_155      AAQSDGVRAIAVSHRIGPLKIGDAALVAAVAADHRRAAFETCARLVDVVK
MAB_0866|M.abscessus_ATCC_1997      AEEADGVRAVAVSHRIGALMVGEAAFVVAVSADHRRQAFATCQRLVDDVK
Rv3119|M.tuberculosis_H37Rv         EDKAEGVR-VAVAHRTGELQIGDAAVVIGASAPHRAEAFDAARMCIELLK
Mb3352c|M.bovis_AF2122/97           ERQADGVR-VAVAHRTGELRIGDAAVVIGASAPHRAAAFDAARMCIERLK
                                      .: *** :*.:** * * :*:**.* ..:* **  ** :.   :: :*

MMAR_4666|M.marinum_M               ARLPVWKHQFFGDGSEEWVGSA-
MUL_0284|M.ulcerans_Agy99           ARLPVWKHQFFGDGSEEWVGSA-
MAV_0995|M.avium_104                ARLPVWKHQFFADGTDEWVGSA-
Mflv_1702|M.gilvum_PYR-GCK          ERLPVWKHQFFTDGSDEWVNSA-
Mvan_5050|M.vanbaalenii_PYR-1       ERLPVWKHQFFADGSDEWVNSA-
MSMEG_5701|M.smegmatis_MC2_155      ERLPVWKHQHFADGTDEWVNSA-
MAB_0866|M.abscessus_ATCC_1997      AALPVWKHQFFANGTDEWVGSA-
Rv3119|M.tuberculosis_H37Rv         QEVPIWKKEFSSTG-AEWVGDRP
Mb3352c|M.bovis_AF2122/97           QDVPIWKKEFALDG-VEWVANRP
                                      :*:**::.   *  *** .