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M. tuberculosis H37Rv Rv3309c (upp)

annotation: uracil phosphoribosyltransferase
coordinates: 3696470 - 3697093
length: 207

QVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPIRTPLAETVGSRLTKPPL
LVPVLRAGLGMVDEAHAALPEAHVGFVGVARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHT
LGLLISRGAADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAGDRQFGPR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3309cupp-100% (207)uracil phosphoribosyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3337cupp1e-116100.00% (207) uracil phosphoribosyltransferase
M. gilvum PYR-GCKMflv_4836upp3e-8974.40% (207) uracil phosphoribosyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3662c-2e-8371.36% (213) Uracil phosphoribosyltransferase
M. marinum MMMAR_1217upp2e-9582.13% (207) uracil phosphoribosyltransferase Upp
M. avium 104MAV_4285upp6e-8776.21% (206) uracil phosphoribosyltransferase
M. smegmatis MC2 155MSMEG_1694upp1e-9176.81% (207) uracil phosphoribosyltransferase
M. thermoresistible (build 8)TH_2261upp1e-8874.40% (207) PROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP
M. ulcerans Agy99MUL_2675upp2e-8380.21% (187) uracil phosphoribosyltransferase Upp
M. vanbaalenii PYR-1Mvan_1600upp2e-9076.33% (207) uracil phosphoribosyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1694|M.smegmatis_MC2_155      ----------------------------------------------MDVR
TH_2261|M.thermoresistible__bu      ----------------------------------------------MKVR
Mflv_4836|M.gilvum_PYR-GCK          -----------------------------MFRTSRIPVRFPLRSGSMDVR
Mvan_1600|M.vanbaalenii_PYR-1       ----------------------------------------------MDVR
MAB_3662c|M.abscessus_ATCC_199      ----------------------------------------------MHVH
Rv3309c|M.tuberculosis_H37Rv        ----------------------------------------------MQVH
Mb3337c|M.bovis_AF2122/97           ----------------------------------------------MQVH
MMAR_1217|M.marinum_M               ----------------------------------------------MEVH
MUL_2675|M.ulcerans_Agy99           --------------------------------------------------
MAV_4285|M.avium_104                MRRRSAFCDFDFRATRPEYTNGGKAFPAGGQACQRGFARSLYTLDQMDVC
                                                                                      

MSMEG_1694|M.smegmatis_MC2_155      VVDHPLAAARLTTLRDERTDNAAFRAALRDLTLMLVYEATRDAPSEQIPV
TH_2261|M.thermoresistible__bu      IVDHPLAATRLTTLRDARTDNATFRAALRDLTVMLVYEATRDIATDTIPV
Mflv_4836|M.gilvum_PYR-GCK          VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRELATHTISV
Mvan_1600|M.vanbaalenii_PYR-1       VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRDLEVEVVSV
MAB_3662c|M.abscessus_ATCC_199      VVEHPLAAARLTTLRDARSDNAAFRTALRDLTLMLVYEATGSVPVESSTV
Rv3309c|M.tuberculosis_H37Rv        VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
Mb3337c|M.bovis_AF2122/97           VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
MMAR_1217|M.marinum_M               VIDHPLAAARLTALRDERTGNAAFRKALRELTLVLVYEATRAAPTESVAI
MUL_2675|M.ulcerans_Agy99           --------------MTKRTGNAAFRQALRELTLVPVYEATRAAPTESVAI
MAV_4285|M.avium_104                VIDHPLAAARLTVLRDERTDTAGFRAALRDLTLMLVYEASRDAPRKSVRI
                                                     *:..* ** ***:**:: :***:     .   :

MSMEG_1694|M.smegmatis_MC2_155      RTPVTDTVGSRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE
TH_2261|M.thermoresistible__bu      LTPLAETTGCRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE
Mflv_4836|M.gilvum_PYR-GCK          RTPVAETAGTKLATPPLLVPVLRAGLGMVDQAHELIPEARVGFVGVARNE
Mvan_1600|M.vanbaalenii_PYR-1       RTPLAETAGTRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGLVRNE
MAB_3662c|M.abscessus_ATCC_199      RTPVAETTGYRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGMARDE
Rv3309c|M.tuberculosis_H37Rv        RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE
Mb3337c|M.bovis_AF2122/97           RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE
MMAR_1217|M.marinum_M               RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE
MUL_2675|M.ulcerans_Agy99           RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE
MAV_4285|M.avium_104                RTPVAAAAGTRLVNPPLLVPVLRAGLGMVDPAQAALPEAEVGFVGVARDE
                                     **:: :.* :*..**************** *:  :***.*****:.*:*

MSMEG_1694|M.smegmatis_MC2_155      TTHQPTPYLASLPDDLSERAVFVLDPMLATGGSMAHTIGLLQARNAVDIT
TH_2261|M.thermoresistible__bu      QTHRPVPYLESLPGDLSDRPVLVLDPMLATGGSMVHTLKLLQERNAVDIT
Mflv_4836|M.gilvum_PYR-GCK          ETHQPTPYLESLPDDLSRQPVIVLDPMLATGGSMVHTLELLYSRDAVDVT
Mvan_1600|M.vanbaalenii_PYR-1       ETHTPTPYLESLPDDLSKQPVIVLDPMLATGGSMVHTLELLYARDAVDVT
MAB_3662c|M.abscessus_ATCC_199      DTWQPTPYLESLPADLSAQPVFVLDPMLATGGSMVYTLELLHARGAADIT
Rv3309c|M.tuberculosis_H37Rv        QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT
Mb3337c|M.bovis_AF2122/97           QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT
MMAR_1217|M.marinum_M               QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT
MUL_2675|M.ulcerans_Agy99           QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT
MAV_4285|M.avium_104                QTHRPVPYLAALPDKLAGRSVMVLDPMLATGGSMAHTLGLLQRRGATDIT
                                     *  *.*** :** .*:  .*:*****:******..*: **  *.*.*:*

MSMEG_1694|M.smegmatis_MC2_155      AVCVVCAPQGIAALEAVAP------DMRLITATVDEGLNEIAYIVPGLGD
TH_2261|M.thermoresistible__bu      ALCVVAAPEGLAAVEQVRP------DLRLFTAAVDERLNEIAFIVPGLGD
Mflv_4836|M.gilvum_PYR-GCK          VICVVAAPEGLALVEKTAP------ELRLYTAAIDSGLNDIAYIVPGLGD
Mvan_1600|M.vanbaalenii_PYR-1       VICVVAAPEGIAALEKMAP------ELRLYTATIDSGLNDIAYIVPGLGD
MAB_3662c|M.abscessus_ATCC_199      MLCVVAAPQGVTAIQECAERFGPSTSVRLFTATIDEGLNDAAYIVPGLGD
Rv3309c|M.tuberculosis_H37Rv        VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD
Mb3337c|M.bovis_AF2122/97           VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD
MMAR_1217|M.marinum_M               VLCVVAAPQGVAALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD
MUL_2675|M.ulcerans_Agy99           VLCVVAAPQGVSALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD
MAV_4285|M.avium_104                VLCVVAAPEGLAAVGETAP------DARVFTAAVDKGLNKAAYIVPGLGD
                                     :***.**:*:: :           . *: *.::*. **. *:*******

MSMEG_1694|M.smegmatis_MC2_155      AGDRQFGPR-----------------------------------------
TH_2261|M.thermoresistible__bu      AGDRQFGPR-----------------------------------------
Mflv_4836|M.gilvum_PYR-GCK          AGDRQFGPR-----------------------------------------
Mvan_1600|M.vanbaalenii_PYR-1       AGDRQFGPR-----------------------------------------
MAB_3662c|M.abscessus_ATCC_199      AGDRQFGPR-----------------------------------------
Rv3309c|M.tuberculosis_H37Rv        AGDRQFGPR-----------------------------------------
Mb3337c|M.bovis_AF2122/97           AGDRQFGPR-----------------------------------------
MMAR_1217|M.marinum_M               AGDRQFGPR-----------------------------------------
MUL_2675|M.ulcerans_Agy99           AGDRQFGPR-----------------------------------------
MAV_4285|M.avium_104                AGDRQFGPNLFTSSAPSRPEAPAGRGRAAAKMPGRRSARSESPSSTSPSA
                                    ********.                                         

MSMEG_1694|M.smegmatis_MC2_155      ---------
TH_2261|M.thermoresistible__bu      ---------
Mflv_4836|M.gilvum_PYR-GCK          ---------
Mvan_1600|M.vanbaalenii_PYR-1       ---------
MAB_3662c|M.abscessus_ATCC_199      ---------
Rv3309c|M.tuberculosis_H37Rv        ---------
Mb3337c|M.bovis_AF2122/97           ---------
MMAR_1217|M.marinum_M               ---------
MUL_2675|M.ulcerans_Agy99           ---------
MAV_4285|M.avium_104                RSRKAAPPA