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QVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPIRTPLAETVGSRLTKPPL LVPVLRAGLGMVDEAHAALPEAHVGFVGVARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHT LGLLISRGAADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAGDRQFGPR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv3309c | upp | - | 100% (207) | uracil phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3337c | upp | 1e-116 | 100.00% (207) | uracil phosphoribosyltransferase |
M. gilvum PYR-GCK | Mflv_4836 | upp | 3e-89 | 74.40% (207) | uracil phosphoribosyltransferase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3662c | - | 2e-83 | 71.36% (213) | Uracil phosphoribosyltransferase |
M. marinum M | MMAR_1217 | upp | 2e-95 | 82.13% (207) | uracil phosphoribosyltransferase Upp |
M. avium 104 | MAV_4285 | upp | 6e-87 | 76.21% (206) | uracil phosphoribosyltransferase |
M. smegmatis MC2 155 | MSMEG_1694 | upp | 1e-91 | 76.81% (207) | uracil phosphoribosyltransferase |
M. thermoresistible (build 8) | TH_2261 | upp | 1e-88 | 74.40% (207) | PROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP |
M. ulcerans Agy99 | MUL_2675 | upp | 2e-83 | 80.21% (187) | uracil phosphoribosyltransferase Upp |
M. vanbaalenii PYR-1 | Mvan_1600 | upp | 2e-90 | 76.33% (207) | uracil phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_1694|M.smegmatis_MC2_155 ----------------------------------------------MDVR TH_2261|M.thermoresistible__bu ----------------------------------------------MKVR Mflv_4836|M.gilvum_PYR-GCK -----------------------------MFRTSRIPVRFPLRSGSMDVR Mvan_1600|M.vanbaalenii_PYR-1 ----------------------------------------------MDVR MAB_3662c|M.abscessus_ATCC_199 ----------------------------------------------MHVH Rv3309c|M.tuberculosis_H37Rv ----------------------------------------------MQVH Mb3337c|M.bovis_AF2122/97 ----------------------------------------------MQVH MMAR_1217|M.marinum_M ----------------------------------------------MEVH MUL_2675|M.ulcerans_Agy99 -------------------------------------------------- MAV_4285|M.avium_104 MRRRSAFCDFDFRATRPEYTNGGKAFPAGGQACQRGFARSLYTLDQMDVC MSMEG_1694|M.smegmatis_MC2_155 VVDHPLAAARLTTLRDERTDNAAFRAALRDLTLMLVYEATRDAPSEQIPV TH_2261|M.thermoresistible__bu IVDHPLAATRLTTLRDARTDNATFRAALRDLTVMLVYEATRDIATDTIPV Mflv_4836|M.gilvum_PYR-GCK VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRELATHTISV Mvan_1600|M.vanbaalenii_PYR-1 VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRDLEVEVVSV MAB_3662c|M.abscessus_ATCC_199 VVEHPLAAARLTTLRDARSDNAAFRTALRDLTLMLVYEATGSVPVESSTV Rv3309c|M.tuberculosis_H37Rv VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI Mb3337c|M.bovis_AF2122/97 VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI MMAR_1217|M.marinum_M VIDHPLAAARLTALRDERTGNAAFRKALRELTLVLVYEATRAAPTESVAI MUL_2675|M.ulcerans_Agy99 --------------MTKRTGNAAFRQALRELTLVPVYEATRAAPTESVAI MAV_4285|M.avium_104 VIDHPLAAARLTVLRDERTDTAGFRAALRDLTLMLVYEASRDAPRKSVRI *:..* ** ***:**:: :***: . : MSMEG_1694|M.smegmatis_MC2_155 RTPVTDTVGSRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE TH_2261|M.thermoresistible__bu LTPLAETTGCRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE Mflv_4836|M.gilvum_PYR-GCK RTPVAETAGTKLATPPLLVPVLRAGLGMVDQAHELIPEARVGFVGVARNE Mvan_1600|M.vanbaalenii_PYR-1 RTPLAETAGTRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGLVRNE MAB_3662c|M.abscessus_ATCC_199 RTPVAETTGYRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGMARDE Rv3309c|M.tuberculosis_H37Rv RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE Mb3337c|M.bovis_AF2122/97 RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE MMAR_1217|M.marinum_M RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE MUL_2675|M.ulcerans_Agy99 RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE MAV_4285|M.avium_104 RTPVAAAAGTRLVNPPLLVPVLRAGLGMVDPAQAALPEAEVGFVGVARDE **:: :.* :*..**************** *: :***.*****:.*:* MSMEG_1694|M.smegmatis_MC2_155 TTHQPTPYLASLPDDLSERAVFVLDPMLATGGSMAHTIGLLQARNAVDIT TH_2261|M.thermoresistible__bu QTHRPVPYLESLPGDLSDRPVLVLDPMLATGGSMVHTLKLLQERNAVDIT Mflv_4836|M.gilvum_PYR-GCK ETHQPTPYLESLPDDLSRQPVIVLDPMLATGGSMVHTLELLYSRDAVDVT Mvan_1600|M.vanbaalenii_PYR-1 ETHTPTPYLESLPDDLSKQPVIVLDPMLATGGSMVHTLELLYARDAVDVT MAB_3662c|M.abscessus_ATCC_199 DTWQPTPYLESLPADLSAQPVFVLDPMLATGGSMVYTLELLHARGAADIT Rv3309c|M.tuberculosis_H37Rv QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT Mb3337c|M.bovis_AF2122/97 QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT MMAR_1217|M.marinum_M QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT MUL_2675|M.ulcerans_Agy99 QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT MAV_4285|M.avium_104 QTHRPVPYLAALPDKLAGRSVMVLDPMLATGGSMAHTLGLLQRRGATDIT * *.*** :** .*: .*:*****:******..*: ** *.*.*:* MSMEG_1694|M.smegmatis_MC2_155 AVCVVCAPQGIAALEAVAP------DMRLITATVDEGLNEIAYIVPGLGD TH_2261|M.thermoresistible__bu ALCVVAAPEGLAAVEQVRP------DLRLFTAAVDERLNEIAFIVPGLGD Mflv_4836|M.gilvum_PYR-GCK VICVVAAPEGLALVEKTAP------ELRLYTAAIDSGLNDIAYIVPGLGD Mvan_1600|M.vanbaalenii_PYR-1 VICVVAAPEGIAALEKMAP------ELRLYTATIDSGLNDIAYIVPGLGD MAB_3662c|M.abscessus_ATCC_199 MLCVVAAPQGVTAIQECAERFGPSTSVRLFTATIDEGLNDAAYIVPGLGD Rv3309c|M.tuberculosis_H37Rv VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD Mb3337c|M.bovis_AF2122/97 VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD MMAR_1217|M.marinum_M VLCVVAAPQGVAALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD MUL_2675|M.ulcerans_Agy99 VLCVVAAPQGVSALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD MAV_4285|M.avium_104 VLCVVAAPEGLAAVGETAP------DARVFTAAVDKGLNKAAYIVPGLGD :***.**:*:: : . *: *.::*. **. *:******* MSMEG_1694|M.smegmatis_MC2_155 AGDRQFGPR----------------------------------------- TH_2261|M.thermoresistible__bu AGDRQFGPR----------------------------------------- Mflv_4836|M.gilvum_PYR-GCK AGDRQFGPR----------------------------------------- Mvan_1600|M.vanbaalenii_PYR-1 AGDRQFGPR----------------------------------------- MAB_3662c|M.abscessus_ATCC_199 AGDRQFGPR----------------------------------------- Rv3309c|M.tuberculosis_H37Rv AGDRQFGPR----------------------------------------- Mb3337c|M.bovis_AF2122/97 AGDRQFGPR----------------------------------------- MMAR_1217|M.marinum_M AGDRQFGPR----------------------------------------- MUL_2675|M.ulcerans_Agy99 AGDRQFGPR----------------------------------------- MAV_4285|M.avium_104 AGDRQFGPNLFTSSAPSRPEAPAGRGRAAAKMPGRRSARSESPSSTSPSA ********. MSMEG_1694|M.smegmatis_MC2_155 --------- TH_2261|M.thermoresistible__bu --------- Mflv_4836|M.gilvum_PYR-GCK --------- Mvan_1600|M.vanbaalenii_PYR-1 --------- MAB_3662c|M.abscessus_ATCC_199 --------- Rv3309c|M.tuberculosis_H37Rv --------- Mb3337c|M.bovis_AF2122/97 --------- MMAR_1217|M.marinum_M --------- MUL_2675|M.ulcerans_Agy99 --------- MAV_4285|M.avium_104 RSRKAAPPA