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FRTSRIPVRFPLRSGSMDVRVVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRELATHTISV RTPVAETAGTKLATPPLLVPVLRAGLGMVDQAHELIPEARVGFVGVARNEETHQPTPYLESLPDDLSRQP VIVLDPMLATGGSMVHTLELLYSRDAVDVTVICVVAAPEGLALVEKTAPELRLYTAAIDSGLNDIAYIVP GLGDAGDRQFGPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4836 | upp | - | 100% (224) | uracil phosphoribosyltransferase |
| M. gilvum PYR-GCK | Mflv_3259 | - | 9e-40 | 37.38% (206) | uracil phosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3337c | upp | 3e-89 | 74.40% (207) | uracil phosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv3309c | upp | 3e-89 | 74.40% (207) | uracil phosphoribosyltransferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3662c | - | 6e-85 | 73.24% (213) | Uracil phosphoribosyltransferase |
| M. marinum M | MMAR_1217 | upp | 1e-86 | 73.43% (207) | uracil phosphoribosyltransferase Upp |
| M. avium 104 | MAV_4285 | upp | 1e-83 | 72.82% (206) | uracil phosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_1694 | upp | 5e-91 | 77.78% (207) | uracil phosphoribosyltransferase |
| M. thermoresistible (build 8) | TH_2261 | upp | 1e-91 | 78.74% (207) | PROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP |
| M. ulcerans Agy99 | MUL_2675 | upp | 6e-76 | 71.66% (187) | uracil phosphoribosyltransferase Upp |
| M. vanbaalenii PYR-1 | Mvan_1600 | upp | 1e-105 | 90.34% (207) | uracil phosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4836|M.gilvum_PYR-GCK -----------------------------MFRTSRIPVRFPLRSGSMDVR
Mvan_1600|M.vanbaalenii_PYR-1 ----------------------------------------------MDVR
MAB_3662c|M.abscessus_ATCC_199 ----------------------------------------------MHVH
MSMEG_1694|M.smegmatis_MC2_155 ----------------------------------------------MDVR
TH_2261|M.thermoresistible__bu ----------------------------------------------MKVR
Mb3337c|M.bovis_AF2122/97 ----------------------------------------------MQVH
Rv3309c|M.tuberculosis_H37Rv ----------------------------------------------MQVH
MMAR_1217|M.marinum_M ----------------------------------------------MEVH
MUL_2675|M.ulcerans_Agy99 --------------------------------------------------
MAV_4285|M.avium_104 MRRRSAFCDFDFRATRPEYTNGGKAFPAGGQACQRGFARSLYTLDQMDVC
Mflv_4836|M.gilvum_PYR-GCK VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRELATHTISV
Mvan_1600|M.vanbaalenii_PYR-1 VVDHPLAAARLTTLRDERTDNAGFRAALRDLTLMLVYEATRDLEVEVVSV
MAB_3662c|M.abscessus_ATCC_199 VVEHPLAAARLTTLRDARSDNAAFRTALRDLTLMLVYEATGSVPVESSTV
MSMEG_1694|M.smegmatis_MC2_155 VVDHPLAAARLTTLRDERTDNAAFRAALRDLTLMLVYEATRDAPSEQIPV
TH_2261|M.thermoresistible__bu IVDHPLAATRLTTLRDARTDNATFRAALRDLTVMLVYEATRDIATDTIPV
Mb3337c|M.bovis_AF2122/97 VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
Rv3309c|M.tuberculosis_H37Rv VVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPI
MMAR_1217|M.marinum_M VIDHPLAAARLTALRDERTGNAAFRKALRELTLVLVYEATRAAPTESVAI
MUL_2675|M.ulcerans_Agy99 --------------MTKRTGNAAFRQALRELTLVPVYEATRAAPTESVAI
MAV_4285|M.avium_104 VIDHPLAAARLTVLRDERTDTAGFRAALRDLTLMLVYEASRDAPRKSVRI
*:..* ** ***:**:: :***: . :
Mflv_4836|M.gilvum_PYR-GCK RTPVAETAGTKLATPPLLVPVLRAGLGMVDQAHELIPEARVGFVGVARNE
Mvan_1600|M.vanbaalenii_PYR-1 RTPLAETAGTRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGLVRNE
MAB_3662c|M.abscessus_ATCC_199 RTPVAETTGYRLANPPLLVPVLRAGLGMVDQAHALIPEARVGFVGMARDE
MSMEG_1694|M.smegmatis_MC2_155 RTPVTDTVGSRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE
TH_2261|M.thermoresistible__bu LTPLAETTGCRLANPPLLVPVLRAGLGMVDQAHALIPEAQVGFVGVARDE
Mb3337c|M.bovis_AF2122/97 RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE
Rv3309c|M.tuberculosis_H37Rv RTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDE
MMAR_1217|M.marinum_M RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE
MUL_2675|M.ulcerans_Agy99 RTPLAATTGLRLANPPLLVPVLRAGLGMVDEAHAALPEARVGFVGIARNE
MAV_4285|M.avium_104 RTPVAAAAGTRLVNPPLLVPVLRAGLGMVDPAQAALPEAEVGFVGVARDE
**:: :.* :*..**************** *: :***.*****:.*:*
Mflv_4836|M.gilvum_PYR-GCK ETHQPTPYLESLPDDLSRQPVIVLDPMLATGGSMVHTLELLYSRDAVDVT
Mvan_1600|M.vanbaalenii_PYR-1 ETHTPTPYLESLPDDLSKQPVIVLDPMLATGGSMVHTLELLYARDAVDVT
MAB_3662c|M.abscessus_ATCC_199 DTWQPTPYLESLPADLSAQPVFVLDPMLATGGSMVYTLELLHARGAADIT
MSMEG_1694|M.smegmatis_MC2_155 TTHQPTPYLASLPDDLSERAVFVLDPMLATGGSMAHTIGLLQARNAVDIT
TH_2261|M.thermoresistible__bu QTHRPVPYLESLPGDLSDRPVLVLDPMLATGGSMVHTLKLLQERNAVDIT
Mb3337c|M.bovis_AF2122/97 QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT
Rv3309c|M.tuberculosis_H37Rv QTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADIT
MMAR_1217|M.marinum_M QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT
MUL_2675|M.ulcerans_Agy99 QTHQPVPYLESLPDDLSGLPVMVLDPMLATGGSMTFTVDLLLSRGATDIT
MAV_4285|M.avium_104 QTHRPVPYLAALPDKLAGRSVMVLDPMLATGGSMAHTLGLLQRRGATDIT
* *.*** :** .*: .*:*****:******..*: ** *.*.*:*
Mflv_4836|M.gilvum_PYR-GCK VICVVAAPEGLALVEKTAP------ELRLYTAAIDSGLNDIAYIVPGLGD
Mvan_1600|M.vanbaalenii_PYR-1 VICVVAAPEGIAALEKMAP------ELRLYTATIDSGLNDIAYIVPGLGD
MAB_3662c|M.abscessus_ATCC_199 MLCVVAAPQGVTAIQECAERFGPSTSVRLFTATIDEGLNDAAYIVPGLGD
MSMEG_1694|M.smegmatis_MC2_155 AVCVVCAPQGIAALEAVAP------DMRLITATVDEGLNEIAYIVPGLGD
TH_2261|M.thermoresistible__bu ALCVVAAPEGLAAVEQVRP------DLRLFTAAVDERLNEIAFIVPGLGD
Mb3337c|M.bovis_AF2122/97 VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD
Rv3309c|M.tuberculosis_H37Rv VLCVVAAPEGIAALQKAAP------NVRLFTAAIDEGLNEVAYIVPGLGD
MMAR_1217|M.marinum_M VLCVVAAPQGVAALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD
MUL_2675|M.ulcerans_Agy99 VLCVVAAPQGVSALEKAAP------NARLFTVAIDDGLNEEAYIVPGLGD
MAV_4285|M.avium_104 VLCVVAAPEGLAAVGETAP------DARVFTAAVDKGLNKAAYIVPGLGD
:***.**:*:: : . *: *.::*. **. *:*******
Mflv_4836|M.gilvum_PYR-GCK AGDRQFGPR-----------------------------------------
Mvan_1600|M.vanbaalenii_PYR-1 AGDRQFGPR-----------------------------------------
MAB_3662c|M.abscessus_ATCC_199 AGDRQFGPR-----------------------------------------
MSMEG_1694|M.smegmatis_MC2_155 AGDRQFGPR-----------------------------------------
TH_2261|M.thermoresistible__bu AGDRQFGPR-----------------------------------------
Mb3337c|M.bovis_AF2122/97 AGDRQFGPR-----------------------------------------
Rv3309c|M.tuberculosis_H37Rv AGDRQFGPR-----------------------------------------
MMAR_1217|M.marinum_M AGDRQFGPR-----------------------------------------
MUL_2675|M.ulcerans_Agy99 AGDRQFGPR-----------------------------------------
MAV_4285|M.avium_104 AGDRQFGPNLFTSSAPSRPEAPAGRGRAAAKMPGRRSARSESPSSTSPSA
********.
Mflv_4836|M.gilvum_PYR-GCK ---------
Mvan_1600|M.vanbaalenii_PYR-1 ---------
MAB_3662c|M.abscessus_ATCC_199 ---------
MSMEG_1694|M.smegmatis_MC2_155 ---------
TH_2261|M.thermoresistible__bu ---------
Mb3337c|M.bovis_AF2122/97 ---------
Rv3309c|M.tuberculosis_H37Rv ---------
MMAR_1217|M.marinum_M ---------
MUL_2675|M.ulcerans_Agy99 ---------
MAV_4285|M.avium_104 RSRKAAPPA