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RFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASVEAYIRHCREQWVTGGPLRSFG IRTVAETIVGTIDLRFDGEGLASGQVNVAYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENS ASARVALRAGFAFVRRICEQDGTVFDRYERVLRAKMHADEVDIDEDLVRRLLRAQFPQWADLPIAPVRSA GTDNAMYRLGEDLAVRIPRIGWAIESLRTEQQWLPRIAAHLGVASPVPVGLGSPAEGFGWPWSVCRWVAG ENPSAAEFVEPNRAVEDLADFITALRATDPMGGPPAKRGAPLGEQDAEVRAALAALDGIIDVHAATAAWE SALRVPPYAGPPMWFHGDLSRFNILTAQGRLTGVIDFGLMGVGDPSVDLIIAWNLLSAPARAQFRVAVGA ADDDWMRGRGRALAIALIALPYYQDTNPPLAASARYAIGEVLADFRYGARPGC*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3225c | - | - | 100% (474) | POSSIBLE TRANSFERASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3254c | - | 0.0 | 99.79% (474) | transferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4837c | - | 2e-42 | 34.21% (304) | phosphotransferase |
| M. marinum M | MMAR_2836 | - | 1e-123 | 61.31% (367) | phosphotransferase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3925 | - | 2e-06 | 27.78% (198) | PUTATIVE putative acyl-CoA dehydrogenase FadE36_1 |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3225c|M.tuberculosis_H37Rv MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASV
Mb3254c|M.bovis_AF2122/97 MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASV
MMAR_2836|M.marinum_M ----MVDPPLSDGTVTLSPFRPDEVSAHVAGQDELTARWLSGGVVTQHSA
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv EAYIRHCREQWVTGGPLRSFGIRT-VAETIVGTIDLRFDGEGLASGQVNV
Mb3254c|M.bovis_AF2122/97 EAYIRHCREQWVTGGPLRSFGIRT-VAETIVGTIDLRFDGEGLASGQVNV
MMAR_2836|M.marinum_M AAYFEHCRDQWATGGPLRAFAIRVGPQQVPAGTVDLRFAGEGLAFGEVNV
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv AYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALR
Mb3254c|M.bovis_AF2122/97 AYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALR
MMAR_2836|M.marinum_M AYGLYPAWRGRGLATRAVDLVCRYAAQLDATVAVVKVEPENSASARVALR
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu ---------MTDTSTRAAEPARSMCDRPAAVAQWLMRNGQSVQEPVTVTR
Rv3225c|M.tuberculosis_H37Rv AGFA---FVRRICEQDGTVFDRYERVLR----------------------
Mb3254c|M.bovis_AF2122/97 AGFA---FVRRICEQDGTVFDRYERVLR----------------------
MMAR_2836|M.marinum_M AGFG---RTSRIREPDGNVFDRYERTLSRGVWVRIAGEADIDAVFEIRTS
MAB_4837c|M.abscessus_ATCC_199 -------------------MLR----------------------------
TH_3925|M.thermoresistible__bu VGFGQSNITSCVSDGAGREWILREPPPG----------------------
Rv3225c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2836|M.marinum_M VTENHLSLEQLAELGITKESVREAMRASPCLWVADVDGVTAGFTMADATA
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_2836|M.marinum_M GSVFACFVRPQFQGRGVGSALMRRVEATLFERHAAIRLTTDGSSRAAGFY
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv --------------------------AKMHADEVDIDEDLVRRLLRAQFP
Mb3254c|M.bovis_AF2122/97 --------------------------AKMHADEVDIDEDLVRRLLRAQFP
MMAR_2836|M.marinum_M RKLGWSAAGDLPDGSIRFEKRLRAPAAKMHADEVDIDASLVRRLVSTQFP
MAB_4837c|M.abscessus_ATCC_199 -------------------------AVDMHAGQVRITSSVVRGLIDAQFP
TH_3925|M.thermoresistible__bu -------------------------AAVGSAHDVHREARIIAALESSGIP
. * :* :: * : :*
Rv3225c|M.tuberculosis_H37Rv QWADLPIAPVRSAGTDNAMYRLGEDLAVRIPRIG----WAIESLRTEQQW
Mb3254c|M.bovis_AF2122/97 QWADLPIAPVRSAGTDNAMYRLGEDLAVRIPRIG----WAIESLRTEQQW
MMAR_2836|M.marinum_M HWADLPLTPIDSAGTDNAMYRLGTDMAVRLPRIH----WAVASLRTEQRW
MAB_4837c|M.abscessus_ATCC_199 QWRVQPIRPVQSVGTVNAIFRIGSQFAARFPLQGEDPGAVLQQLQAESDA
TH_3925|M.thermoresistible__bu VPRVVGMGRSPDGSPFFVMERVNGRALESEQDAG---PLTPAQRQQIGRQ
: . .. .: *:. . . :
Rv3225c|M.tuberculosis_H37Rv LPRIAAHLGVASPVPVGLGSPAEGFGWPWSVCRWVAGENPSAAEFVEPNR
Mb3254c|M.bovis_AF2122/97 LPRIAAHLGVASPVPVGLGSPAEGFGWPWSVCRWVAGENPSAAEFVEPNR
MMAR_2836|M.marinum_M LGRIAPQLPVASPVPVGLGAAAQGFAWPWSICRWVTGENPKFGQLVDPIG
MAB_4837c|M.abscessus_ATCC_199 AAKLVGRTRFPTPEPVAIGSPGPGYGLPWSVQTWLPGVVATGRDPGDSAG
TH_3925|M.thermoresistible__bu VATILGRLHTLDTGRLGLPEPRSPY-LERQIRRVTQAWDVYGRDTRHDAG
: : . :.: . : .: . : .
Rv3225c|M.tuberculosis_H37Rv AVEDLADFITALRATDPMGG--PPAKRGAPLGEQDAEVRAALAALDGIID
Mb3254c|M.bovis_AF2122/97 AVEDLADFITTLRATDPMGG--PPAKRGAPLGEQDAEVRAALAALDGIID
MMAR_2836|M.marinum_M LARDLADFIGALRRIDPAGG--PDAARGKPLAEQDEQVRGALATMDGRLD
MAB_4837c|M.abscessus_ATCC_199 FARDLAEFVAGVRMISTGGKNFEGPGRGGVIALHDEWMQMCFERSAGLLD
TH_3925|M.thermoresistible__bu WQRLRDGLAQSMPARSAPPVIMHGDLRLSNMLVDGGEVTAVLDWELAAIG
. : : .. * : .. : : . :.
Rv3225c|M.tuberculosis_H37Rv VHAATAAWESALRVPPYAGPPMWFHGDLSRFNILT-AQGRLTGVIDFGLM
Mb3254c|M.bovis_AF2122/97 VHAATAAWESALRVPPYAGPPMWFHGDLSRFNILT-AQGRLTGVIDFGLM
MMAR_2836|M.marinum_M VHAVTVAWERALRIPGYAGPPTWFHGDLSPFNILT-VDGRLAGVIDFGLM
MAB_4837c|M.abscessus_ATCC_199 VPRLRQVWAQMRELPRGSDVDVTSHRDLIPGNMLVSGEGRLAGVLDAGGL
TH_3925|M.thermoresistible__bu DPLADLAWLLDDWRAP------------EEPGIVMPSPTRAGGFPDRDEM
.* . .:: * *. * . :
Rv3225c|M.tuberculosis_H37Rv GVGDPSVDLIIAWNLLSAPARAQFRVAVGAADDDWMRGRGRALAIALIAL
Mb3254c|M.bovis_AF2122/97 GVGDPSVDLIIAWNLLSAPARAQFRVAVGAADDDWMRGRGRALAIALIAL
MMAR_2836|M.marinum_M GVGDPSVDLIPAWNLLSAPAREQFRTMLRVDAETWARGCGRALSIALVAL
MAB_4837c|M.abscessus_ATCC_199 GPADPALDLVGAWHLLDAAARKVFRESLRPDELQWQRGRAWAFQQAMGLV
TH_3925|M.thermoresistible__bu IEIYHAVSGVPVDGIDYYRAFSQWRAAGLLQGVLVRRRKGQMGDHGAVDL
::. : . : * :* * . . :
Rv3225c|M.tuberculosis_H37Rv PYYQDTNPPLAASARYAIGEVLADFRYGARPGC-
Mb3254c|M.bovis_AF2122/97 PYYQDTNPPLAASARYAIGEVLADFRYGARPGC-
MMAR_2836|M.marinum_M PYYQTTNPQLAGSARHVISEILADQRRSGSLGSW
MAB_4837c|M.abscessus_ATCC_199 WYYANSNPAMSRVGRRTLDRLLADSS--------
TH_3925|M.thermoresistible__bu EQLDSSIATLLSSAAEHLARCTGAGPRTG-----
: . : . : . .