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VDPPLSDGTVTLSPFRPDEVSAHVAGQDELTARWLSGGVVTQHSAAAYFEHCRDQWATGGPLRAFAIRVG PQQVPAGTVDLRFAGEGLAFGEVNVAYGLYPAWRGRGLATRAVDLVCRYAAQLDATVAVVKVEPENSASA RVALRAGFGRTSRIREPDGNVFDRYERTLSRGVWVRIAGEADIDAVFEIRTSVTENHLSLEQLAELGITK ESVREAMRASPCLWVADVDGVTAGFTMADATAGSVFACFVRPQFQGRGVGSALMRRVEATLFERHAAIRL TTDGSSRAAGFYRKLGWSAAGDLPDGSIRFEKRLRAPAAKMHADEVDIDASLVRRLVSTQFPHWADLPLT PIDSAGTDNAMYRLGTDMAVRLPRIHWAVASLRTEQRWLGRIAPQLPVASPVPVGLGAAAQGFAWPWSIC RWVTGENPKFGQLVDPIGLARDLADFIGALRRIDPAGGPDAARGKPLAEQDEQVRGALATMDGRLDVHAV TVAWERALRIPGYAGPPTWFHGDLSPFNILTVDGRLAGVIDFGLMGVGDPSVDLIPAWNLLSAPAREQFR TMLRVDAETWARGCGRALSIALVALPYYQTTNPQLAGSARHVISEILADQRRSGSLGSW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2836 | - | - | 100% (620) | phosphotransferase |
| M. marinum M | MMAR_5309 | - | 1e-05 | 25.69% (253) | hypothetical protein MMAR_5309 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3254c | - | 1e-122 | 60.82% (365) | transferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3225c | - | 1e-123 | 61.10% (365) | transferase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4837c | - | 5e-45 | 35.22% (301) | phosphotransferase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2069 | - | 8e-05 | 29.11% (158) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_3925 | - | 1e-07 | 29.56% (203) | PUTATIVE putative acyl-CoA dehydrogenase FadE36_1 |
| M. ulcerans Agy99 | MUL_4383 | - | 5e-05 | 25.30% (253) | hypothetical protein MUL_4383 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3254c|M.bovis_AF2122/97 MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASV
Rv3225c|M.tuberculosis_H37Rv MRFAKLSDGLSDGIVTLSPLCLDDVDAHLAGGDERLVRWLSGMPSTRASV
MMAR_2836|M.marinum_M ----MVDPPLSDGTVTLSPFRPDEVSAHVAGQDELTARWLSGGVVTQHSA
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
MUL_4383|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2069|M.smegmatis_MC2_155 --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 EAYIRHCREQWVTGGPLRSFGIRT-VAETIVGTIDLRFDGEGLASGQVNV
Rv3225c|M.tuberculosis_H37Rv EAYIRHCREQWVTGGPLRSFGIRT-VAETIVGTIDLRFDGEGLASGQVNV
MMAR_2836|M.marinum_M AAYFEHCRDQWATGGPLRAFAIRVGPQQVPAGTVDLRFAGEGLAFGEVNV
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
MUL_4383|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2069|M.smegmatis_MC2_155 --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 AYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALR
Rv3225c|M.tuberculosis_H37Rv AYGLYPSWRGRGLATRAVDLVCQYAAEHGATEAVIKVEPENSASARVALR
MMAR_2836|M.marinum_M AYGLYPAWRGRGLATRAVDLVCRYAAQLDATVAVVKVEPENSASARVALR
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu ---------MTDTSTRAAEPARSMCDRPAAVAQWLMRNGQSVQEPVTVTR
MUL_4383|M.ulcerans_Agy99 -----------------METEGGTSLNAAVLGRWLDSRHAPGSGEEPVLE
MSMEG_2069|M.smegmatis_MC2_155 -------------MTETRDPASLTGGLVDVLAPVVG-AGVSVENLRELTG
Mb3254c|M.bovis_AF2122/97 AGFA---FVRRICEQDGTVFDRYERVLR----------------------
Rv3225c|M.tuberculosis_H37Rv AGFA---FVRRICEQDGTVFDRYERVLR----------------------
MMAR_2836|M.marinum_M AGFG---RTSRIREPDGNVFDRYERTLSRGVWVRIAGEADIDAVFEIRTS
MAB_4837c|M.abscessus_ATCC_199 -------------------MLR----------------------------
TH_3925|M.thermoresistible__bu VGFGQSNITSCVSDGAGREWILREPPPG----------------------
MUL_4383|M.ulcerans_Agy99 QLGGGSQNTLYLVRRGDQSMVLRMPGPR----------------------
MSMEG_2069|M.smegmatis_MC2_155 GASRTTWSFEAVTASQRRALILRTGPPD----------------------
Mb3254c|M.bovis_AF2122/97 --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2836|M.marinum_M VTENHLSLEQLAELGITKESVREAMRASPCLWVADVDGVTAGFTMADATA
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
MUL_4383|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2069|M.smegmatis_MC2_155 --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 --------------------------------------------------
Rv3225c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2836|M.marinum_M GSVFACFVRPQFQGRGVGSALMRRVEATLFERHAAIRLTTDGSSRAAGFY
MAB_4837c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3925|M.thermoresistible__bu --------------------------------------------------
MUL_4383|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2069|M.smegmatis_MC2_155 --------------------------------------------------
Mb3254c|M.bovis_AF2122/97 --------------------------AKMHADEVDIDEDLVRRLLRAQFP
Rv3225c|M.tuberculosis_H37Rv --------------------------AKMHADEVDIDEDLVRRLLRAQFP
MMAR_2836|M.marinum_M RKLGWSAAGDLPDGSIRFEKRLRAPAAKMHADEVDIDASLVRRLVSTQFP
MAB_4837c|M.abscessus_ATCC_199 -------------------------AVDMHAGQVRITSSVVRGLIDAQFP
TH_3925|M.thermoresistible__bu -------------------------AAVGSAHDVHREARIIAALESSGIP
MUL_4383|M.ulcerans_Agy99 -------------------------ADAARIDGLLREIRLVRALSGTDVP
MSMEG_2069|M.smegmatis_MC2_155 ----------------------------EVHAGMELEAGAQRAAAAAGAP
: : *
Mb3254c|M.bovis_AF2122/97 QWADLPIAPVRSAG--TDNAMYRLGEDLAVRIPRIG----WAIESLRTEQ
Rv3225c|M.tuberculosis_H37Rv QWADLPIAPVRSAG--TDNAMYRLGEDLAVRIPRIG----WAIESLRTEQ
MMAR_2836|M.marinum_M HWADLPLTPIDSAG--TDNAMYRLGTDMAVRLPRIH----WAVASLRTEQ
MAB_4837c|M.abscessus_ATCC_199 QWRVQPIRPVQSVG--TVNAIFRIGSQFAARFPLQGEDPGAVLQQLQAES
TH_3925|M.thermoresistible__bu VPRVVGMGRSPDGS--PFFVMERVNGRALESEQDAG---PLTPAQRQQIG
MUL_4383|M.ulcerans_Agy99 HAELIATDETGSVLGMPFYLMRAIDGWSPMDGGWPAP-FDTDLPARRGLA
MSMEG_2069|M.smegmatis_MC2_155 VPHVLVADNSTAALGNPYLVCDFIPGETIVRRIQRQ----LDAAGRAKLL
. :
Mb3254c|M.bovis_AF2122/97 QWLPRIAAHLGVASPVPVGLG-SPAEGFGWPWSVCRWVAGENPSAAEFVE
Rv3225c|M.tuberculosis_H37Rv QWLPRIAAHLGVASPVPVGLG-SPAEGFGWPWSVCRWVAGENPSAAEFVE
MMAR_2836|M.marinum_M RWLGRIAPQLPVASPVPVGLG-AAAQGFAWPWSICRWVTGENPKFGQLVD
MAB_4837c|M.abscessus_ATCC_199 DAAAKLVGRTRFPTPEPVAIG-SPGPGYGLPWSVQTWLPGVVATGRDPGD
TH_3925|M.thermoresistible__bu RQVATILGRLHTLDTGRLGLP-EPRSPY-LERQIRRVTQAWDVYGRDTRH
MUL_4383|M.ulcerans_Agy99 LQLVEGAAKLGRVDWRGQGLEGFGRPDGFHERQVDRWLHFLAAY--QVRE
MSMEG_2069|M.smegmatis_MC2_155 TQCAQALAAIHRAEP-PTDIG------LTELDQVGQWRDQLDEMG---DT
: .:
Mb3254c|M.bovis_AF2122/97 PNRAVEDLADFITTLRATDPMGG--PPAKRGAPLGEQDA--EVRAALAAL
Rv3225c|M.tuberculosis_H37Rv PNRAVEDLADFITALRATDPMGG--PPAKRGAPLGEQDA--EVRAALAAL
MMAR_2836|M.marinum_M PIGLARDLADFIGALRRIDPAGG--PDAARGKPLAEQDE--QVRGALATM
MAB_4837c|M.abscessus_ATCC_199 SAGFARDLAEFVAGVRMISTGGKNFEGPGRGGVIALHDE--WMQMCFERS
TH_3925|M.thermoresistible__bu DAGWQRLRDGLAQSMPARSAPPVIMHGDLRLSNMLVDGG--EVTAVLDWE
MUL_4383|M.ulcerans_Agy99 LPGLDAASDWLRRNRPAHYTPGIMHGDYQFANVMFAHGEPARLAAIVDWA
MSMEG_2069|M.smegmatis_MC2_155 TATFEWAFRWLAANRPPASPPRLIHGDFRMGNLIVDGSD---LAAVLDWE
: . : . : .
Mb3254c|M.bovis_AF2122/97 DGIIDVHAATAAWESALRVPPYAGPPMWFHGDLSRFNILT-AQGRLTGVI
Rv3225c|M.tuberculosis_H37Rv DGIIDVHAATAAWESALRVPPYAGPPMWFHGDLSRFNILT-AQGRLTGVI
MMAR_2836|M.marinum_M DGRLDVHAVTVAWERALRIPGYAGPPTWFHGDLSPFNILT-VDGRLAGVI
MAB_4837c|M.abscessus_ATCC_199 AGLLDVPRLRQVWAQMRELPRGSDVDVTSHRDLIPGNMLVSGEGRLAGVL
TH_3925|M.thermoresistible__bu LAAIGDPLADLAWLLDDWRAP------------EEPGIVMPSPTRAGGFP
MUL_4383|M.ulcerans_Agy99 MTTIGDSRLDLAWSLLGYDGE----------EPRADGFYL----DMSAMP
MSMEG_2069|M.smegmatis_MC2_155 LVHIGEVYEDLAWFCIR-----------------AWRFGATESHAAGGLG
:. .* : ..
Mb3254c|M.bovis_AF2122/97 DFGLMGVGDPSVDLIIAWN--LLSAPARAQFRVAVGAADDDWMRGRG--R
Rv3225c|M.tuberculosis_H37Rv DFGLMGVGDPSVDLIIAWN--LLSAPARAQFRVAVGAADDDWMRGRG--R
MMAR_2836|M.marinum_M DFGLMGVGDPSVDLIPAWN--LLSAPAREQFRTMLRVDAETWARGCG--R
MAB_4837c|M.abscessus_ATCC_199 DAGGLGPADPALDLVGAWH--LLDAAARKVFRESLRPDELQWQRGRA--W
TH_3925|M.thermoresistible__bu DRDEMIEIYHAVSGVPVDG--IDYYRAFSQWRAAGLLQGVLVRRRKG--Q
MUL_4383|M.ulcerans_Agy99 KRSELLEHYEKVSGLSTDN--IDYYLVLANWKLGIVLEKTYAAAVRAGPH
MSMEG_2069|M.smegmatis_MC2_155 SIENFLTAYEDAGGMTLDRDAIRWWLVLATLRWGVICLYQAERHLSG---
. : . : : . : .
Mb3254c|M.bovis_AF2122/97 ALAIALIALPYYQDTNPPLAASARYAIGEVLADFRYGARPGC-
Rv3225c|M.tuberculosis_H37Rv ALAIALIALPYYQDTNPPLAASARYAIGEVLADFRYGARPGC-
MMAR_2836|M.marinum_M ALSIALVALPYYQTTNPQLAGSARHVISEILADQRRSGSLGSW
MAB_4837c|M.abscessus_ATCC_199 AFQQAMGLVWYYANSNPAMSRVGRRTLDRLLADSS--------
TH_3925|M.thermoresistible__bu MGDHGAVDLEQLDSSIATLLSSAAEHLARCTGAGPRTG-----
MUL_4383|M.ulcerans_Agy99 TGGVDPKIKDAFAAMIPRLIATAAELARATKAR----------
MSMEG_2069|M.smegmatis_MC2_155 --QTRSVELATIGRRVCETEWDILTLLDGSTA-----------
.