For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv3204 (-)

annotation: POSSIBLE DNA-METHYLTRANSFERASE (MODIFICATION METHYLASE)
coordinates: 3581315 - 3581620
length: 101

MAPVTDEQVELVRSLVAAIPLGRVSTYGDIAALTGLSSPRIVGWIMRTDSSDLPWHRVIRASGRPAQHLA
TRQLELLRAEGVLSVDGRVALSEIRYEFPPG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3204--100% (101)POSSIBLE DNA-METHYLTRANSFERASE (MODIFICATION METHYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3229-6e-5399.01% (101) DNA-methyltransferase (modification methylase)
M. gilvum PYR-GCKMflv_4668-5e-3773.47% (98) methylated-DNA-(protein)-cysteine S-methyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3518-1e-3977.55% (98) DNA-methyltransferase
M. marinum MMMAR_1354-3e-4583.17% (101) DNA-methyltransferase (modification methylase)
M. avium 104MAV_4152-5e-4179.59% (98) 6-O-methylguanine DNA methyltransferase
M. smegmatis MC2 155MSMEG_1939-4e-3979.59% (98) 6-O-methylguanine DNA methyltransferase
M. thermoresistible (build 8)TH_0448-6e-3879.17% (96) POSSIBLE DNA-METHYLTRANSFERASE (MODIFICATION METHYLASE)
M. ulcerans Agy99MUL_2525-5e-4582.18% (101) DNA-methyltransferase (modification methylase)
M. vanbaalenii PYR-1Mvan_1799-2e-3979.59% (98) methylated-DNA-(protein)-cysteine S-methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Rv3204|M.tuberculosis_H37Rv         MAPVTDEQVELVRSLVAAIPLGRVSTYGDIAALTGLSSPRIVGWIMRTDS
Mb3229|M.bovis_AF2122/97            MAPVTDEQVELVRSLVAAIPLGRVSTYGDIAALAGLSSPRIVGWIMRTDS
MMAR_1354|M.marinum_M               MAPVTDEQVERVRRLVAAIPSGRVATYGDIASAAGLSSPRIVGWIMRTDS
MUL_2525|M.ulcerans_Agy99           MAPVTDEQVERVRRLVAAIPSGRVATYGDIASAAGLSSPRIAGWIMRTDS
MAV_4152|M.avium_104                MAPVTDEQVERVRALVAAIPPGRVATYGDIAAVAGLSSARIVGWIMRTDS
MAB_3518|M.abscessus_ATCC_1997      MAAVTEEQVELVRSLVASIPAGRVATYGDIADAAGLASARIVGWIMRTDS
Mflv_4668|M.gilvum_PYR-GCK          MAAITDDQVEAVRALVAAIPAGRVATYGDIAGAAGLSSPRIVAWIMRTDS
TH_0448|M.thermoresistible__bu      MAPVTDEQVEAVRALVAAIPSGRVVTYGDIAAAAGLSSARTVGWIMRTDS
MSMEG_1939|M.smegmatis_MC2_155      MARVTEEQVEAVRALVAAIPPGTVSTYGDIAEVAGLSSPRIVGWIMRTDS
Mvan_1799|M.vanbaalenii_PYR-1       MAAVTEEQVETVRGLVASVPPGRVTTYGDIADAAGLSSPRIVGWIMRTDS
                                    ** :*::*** ** ***::* * * ******  :**:*.* ..*******

Rv3204|M.tuberculosis_H37Rv         SDLPWHRVIRASGRPAQHLATRQLELLRAEGVLSVDGRVALSEIRYEFPP
Mb3229|M.bovis_AF2122/97            SDLPWHRVIRASGRPAQHLATRQLELLRAEGVLSVDGRVALSEIRYEFPP
MMAR_1354|M.marinum_M               VDLPWHRVITASGRPARHLTNRQLELLRAEGVLSVDGKIALDQVRYEFPP
MUL_2525|M.ulcerans_Agy99           VDLPWHRVITASGRPARHLTSRQLELLRAEGVLSVDGKIALDQVRYEFPP
MAV_4152|M.avium_104                SDLPWHRVITASGRPARHLRTRQLELLRAEGVLATEGRIPLPEVRHRFGA
MAB_3518|M.abscessus_ATCC_1997      ADLPWHRVIGASGRPAPHIRTRQLELLRAEGVLAVDGRIALRDVRHGF--
Mflv_4668|M.gilvum_PYR-GCK          ADLPWHRVIPVSGRPAPHLAGRQLDRLRAEGVLARDGRVPLTQYRHAF--
TH_0448|M.thermoresistible__bu      ADLPWYRVIAASGRPAPHLAARQLELLRTEGVLAVDGRVPLRVYRHRLEI
MSMEG_1939|M.smegmatis_MC2_155      SDLPWHRVVPASGRPAPHLATRQLERLRAEGVLATDGRVPLREYRHIF--
Mvan_1799|M.vanbaalenii_PYR-1       SDLPWHRVIAASGRPAVHLATRQLERLRAEGVLAVDGRVPLREYRHTF--
                                     ****:**: .***** *:  ***: **:****: :*::.*   *: :  

Rv3204|M.tuberculosis_H37Rv         G-
Mb3229|M.bovis_AF2122/97            G-
MMAR_1354|M.marinum_M               GC
MUL_2525|M.ulcerans_Agy99           GC
MAV_4152|M.avium_104                --
MAB_3518|M.abscessus_ATCC_1997      --
Mflv_4668|M.gilvum_PYR-GCK          --
TH_0448|M.thermoresistible__bu      --
MSMEG_1939|M.smegmatis_MC2_155      --
Mvan_1799|M.vanbaalenii_PYR-1       --