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TTPGRPLTTLDKSDVLAGLFAVWHSLDALLDGLLETDWQATSPLPGWDVKAVVSHIIGTESFLLGIAAPE PDTDVSALAHVRNPIGVMNECWVRHLGTESGVGLLERFRAVTSQRRKVLASLSDDEWNAPTTTPSGPDSY GRFMRIRIFDCWMHEQDIRAAVQRPSSDDELGGPASPLVLDEIAATMGFVVGKLAKAPDGSRVLLELTGP LSRSIRVSVDGRARVVDDFGGPAPTATIRLDGLQFTRLAGGRPMSPARSQDVELGGDKELAGHILERLNF VI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3099c | - | - | 100% (283) | hypothetical protein Rv3099c |
| M. tuberculosis H37Rv | Rv0036c | - | 1e-07 | 25.71% (210) | hypothetical protein Rv0036c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3126c | - | 1e-163 | 100.00% (283) | hypothetical protein Mb3126c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0703c | - | 2e-52 | 40.22% (276) | hypothetical protein MAB_0703c |
| M. marinum M | MMAR_1537 | - | 1e-129 | 79.50% (278) | hypothetical protein MMAR_1537 |
| M. avium 104 | MAV_0050 | - | 1e-05 | 24.38% (201) | hypothetical protein MAV_0050 |
| M. smegmatis MC2 155 | MSMEG_6923 | - | 2e-07 | 24.88% (201) | hypothetical protein MSMEG_6923 |
| M. thermoresistible (build 8) | TH_2156 | - | 5e-78 | 52.13% (282) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2397 | - | 1e-128 | 78.78% (278) | hypothetical protein MUL_2397 |
| M. vanbaalenii PYR-1 | Mvan_1122 | - | 1e-32 | 30.51% (272) | hypothetical protein Mvan_1122 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3099c|M.tuberculosis_H37Rv MTTPGRPLTTLDKSDVLAGLFAVWHSLDALLDGLLETDWQATSPLPGWDV
Mb3126c|M.bovis_AF2122/97 MTTPGRPLTTLDKSDVLAGLFAVWHSLDALLDGLLETDWQATSPLPGWDV
MMAR_1537|M.marinum_M MAS--RPLTELDKSDVLAGLFAVWDSIDALLDGLPEADWQAKSPLPGWDV
MUL_2397|M.ulcerans_Agy99 MAS--RPLTELDKSDVLAGLVAVWDSIDALLDGLPEADWQAKSPLPGWDV
TH_2156|M.thermoresistible__bu -----VSITALDKTEILDGLFAVWDDITALGGRLTDAQWQTPTELPGWSV
MAB_0703c|M.abscessus_ATCC_199 -----MTVTIVAKEPVVSALAAEWSALDELGASLTDDQWATPSVLPGWTV
Mvan_1122|M.vanbaalenii_PYR-1 -----MKPDITSAAEVRGALENCFDTYESLCADLSDDEWHAQSLCPDWTV
MAV_0050|M.avium_104 ---------MTGPAPIVADLRAESDALDALVAPLPPGRWADPTPAAGWTI
MSMEG_6923|M.smegmatis_MC2_155 ----------MAAEPIVADLRAESDALDALVADLPEAAWATDTPAQGWTI
: * * * * : .* :
Rv3099c|M.tuberculosis_H37Rv KAVVSHIIGTESFLLGIAAPEPDTDVSALAHVRNPIGVMNECWVRHLGTE
Mb3126c|M.bovis_AF2122/97 KAVVSHIIGTESFLLGIAAPEPDTDVSALAHVRNPIGVMNECWVRHLGTE
MMAR_1537|M.marinum_M KAVVAHLIGTESFLMGVAAPEPDVDVSALGHVRNPIGVMNEYWVRHLCGE
MUL_2397|M.ulcerans_Agy99 KAVVAHLIGTESFLMGVAAAEPDVDVSALGHVRNPIGVMNEYWVRHLCGE
TH_2156|M.thermoresistible__bu HDVLAHLIGIESMLQGVETPDADIDVTTLEHVHNDIGALNERWIRALRGL
MAB_0703c|M.abscessus_ATCC_199 KDVVAHVVGTERLLSGDPIPSTDEAVTDLPHVRNPVGVLNERWLTYYRKL
Mvan_1122|M.vanbaalenii_PYR-1 RGVVDHVTSIEAAMTG-WLPDDGTTPPPFERAGEFLADS-----------
MAV_0050|M.avium_104 AHQIGHLLWTDRVALIAVTDEPGFAEVLAGAAADPAGFVDKG-AEELAAV
MSMEG_6923|M.smegmatis_MC2_155 AHQIGHLLWTDQMALLAVTDEAGFAEAVARAATHPTGFVDEG-AAALAAL
: *: : . . . . .
Rv3099c|M.tuberculosis_H37Rv SGVGLLERFRAVTSQRRKVLASLSDDEWNAPTTTPSGPDSYGRFMRIRIF
Mb3126c|M.bovis_AF2122/97 SGVGLLERFRAVTSQRRKVLASLSDDEWNAPTTTPSGPDSYGRFMRIRIF
MMAR_1537|M.marinum_M SGASLLERFRNVTEKRRKALTDLSNEEWNAATTTPAGPDSYGRFMRIRAF
MUL_2397|M.ulcerans_Agy99 SGASLLERFRNVTEKRRKALTDLSNEEWNAATTTPAGPDSHGRFMRIRVF
TH_2156|M.thermoresistible__bu EPAELLDRWRSVTDERRAALTAMNDEDWSAVTATPAGPDSYGRFMRIRIF
MAB_0703c|M.abscessus_ATCC_199 PPAAVMNDLRTVTSARLAVLEGLSQEQFNAETATPVGPESYGRFMQIRDF
Mvan_1122|M.vanbaalenii_PYR-1 --TPYLDKVRGVFDARRRDLAALTDDDFRRPSWTPIGPGTYGGFLAIRVF
MAV_0050|M.avium_104 APAELLADWRATRDRLHRALLGVPA-GRKLPWFGP--PMSAASMATARLM
MSMEG_6923|M.smegmatis_MC2_155 PASQLLAEWRTTRNRLHDALLGVAD-GRKLPWFGP--PMAAGSMATARLM
: * . . * : * * : . : * :
Rv3099c|M.tuberculosis_H37Rv DCWMHEQDIRAAVQRPSSDDELGGPASPLVLDEIAATMGFVVGKLAKAPD
Mb3126c|M.bovis_AF2122/97 DCWMHEQDIRAAVQRPSSDDELGGPASPLVLDEIAATMGFVVGKLAKAPD
MMAR_1537|M.marinum_M DCWMHEQDIRHALQQESSDEQLAGPASRLSLDEISTSMGFVVGKLAKAPE
MUL_2397|M.ulcerans_Agy99 DCWMHEQDIRHALQQESSDEQLAGPASRLSLDEISTSMGFVVGKLAKAPE
TH_2156|M.thermoresistible__bu DCWMHEHDIRAVTGLTLGDDALDTPPARLALDEMAAAMGRVVGKLGKAPD
MAB_0703c|M.abscessus_ATCC_199 DCWMHELDVRDSLGLPAPTDPVTAAP---ALTELINALPFLIGKRAGAPQ
Mvan_1122|M.vanbaalenii_PYR-1 DFWVHERDITTPLGRTTDD---SGVGAELSLAQVENSIGYIVGKKIGVPD
MAV_0050|M.avium_104 ETWAHGLDVADALGVTRPATDRLRSIAHLGVRTRDYAFAVNN----LTPP
MSMEG_6923|M.smegmatis_MC2_155 ETWAHGLDVADALGVRRPATDRLRSVAHIGVRTRDFAFSVHG----LTPP
: * * *: : :: .*
Rv3099c|M.tuberculosis_H37Rv GSRVLLELTGPLSRSIRVSV-DGRARVVDDFGG-----PAPTATIRLDGL
Mb3126c|M.bovis_AF2122/97 GSRVLLELTGPLSRSIRVSV-DGRARVVDDFGG-----PAPTATIRLDGL
MMAR_1537|M.marinum_M GSRVLFELTGPLTREIRVNV-EGRAQVVDDFGG-----QEPTATIRIDGL
MUL_2397|M.ulcerans_Agy99 GSRVLFELTGPLTREIRVNV-EGRAQVVDDFGG-----QEPTATIRIDGL
TH_2156|M.thermoresistible__bu GSRVRFELLGPLARTIDVAVQDGRGRVVPGFGATGDGDPGPTTVISLDAW
MAB_0703c|M.abscessus_ATCC_199 GSRIRFVLNGVGAQTVNIEI-PDRARIVAALSE------APQVTLTADTC
Mvan_1122|M.vanbaalenii_PYR-1 GKSITFELTGPITRQLHVAV-DGRAARVEHLDD-------PDVVVTTDST
MAV_0050|M.avium_104 AEPFLVELRGPRGDTWSWGPPEAAQRVTGSAED-----FCFLVTQRRPLS
MSMEG_6923|M.smegmatis_MC2_155 AEPFRVELTGPSGELWVWGPEDAAQRVTGVAED-----FCMLVTQRRAPS
.. . . * * . ..
Rv3099c|M.tuberculosis_H37Rv QFTRLAGGRPMSPARSQD--VELGGDKELAGHILERLNFVI
Mb3126c|M.bovis_AF2122/97 QFTRLAGGRPMSPARSQD--VELGGDKELAGHILERLNFVI
MMAR_1537|M.marinum_M QFTRLAGGRPKSPARGQD--IEFGGDKDLAAHIVERLNFVI
MUL_2397|M.ulcerans_Agy99 QFTRLAGGRPKSPARSQD--IEFGGDKDLAAHIVERLNFVI
TH_2156|M.thermoresistible__bu VFTRLAGGRSTPERHPGA--IGYRGDEAVGRRIVENLNYVI
MAB_0703c|M.abscessus_ATCC_199 EFARHLGGR--ASANRNG--FTLDGDPDLGWKIVANLRFTM
Mvan_1122|M.vanbaalenii_PYR-1 TFIQLACGRIDPQAQIDSGKISWTGDDALGDRAARNLRFTM
MAV_0050|M.avium_104 ALDITADGADAQRWLEIA--QAFAGPPGPGR----------
MSMEG_6923|M.smegmatis_MC2_155 QLDVHATGPDAQTWLTIA--QAFAGPPGAGRG---------
: * * .