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GTADRPLDASALRDWAHAVVSDLILHIDEINRLNVFPVADSDTGVNMLFTMRAAVVEADLHANSQADAED VARVAAALAAGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2975c | - | - | 100% (84) | hypothetical protein Rv2975c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2999c | - | 5e-42 | 100.00% (83) | hypothetical protein Mb2999c |
| M. gilvum PYR-GCK | Mflv_4213 | - | 8e-22 | 66.67% (78) | Dak phosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3279c | - | 2e-18 | 61.84% (76) | putative phosphatase/kinase |
| M. marinum M | MMAR_1741 | - | 1e-26 | 65.17% (89) | hypothetical protein MMAR_1741 |
| M. avium 104 | MAV_3819 | - | 9e-25 | 69.62% (79) | DAK2 domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2402 | - | 8e-24 | 69.23% (78) | dihydroxyacetone kinase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2154 | - | 4e-23 | 70.51% (78) | Dak phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4213|M.gilvum_PYR-GCK ---------------MSARRLDASTLRRWAHDAVAALISHTDEINRLNVF
Mvan_2154|M.vanbaalenii_PYR-1 ---------------MSARRLDASALRHWAHAAVADLISHTDEINQLNVF
MSMEG_2402|M.smegmatis_MC2_155 ---------------MSARRLDASALRDWAHTAVGDLITHTDEINRLNVF
Rv2975c|M.tuberculosis_H37Rv ---------MG----TADRPLDASALRDWAHAVVSDLILHIDEINRLNVF
Mb2999c|M.bovis_AF2122/97 ---------MG----TADRPLDASALRDWAHAVVSDLILHIDEINRLNVF
MMAR_1741|M.marinum_M ---------MG----TTERPLDALALRDWAHTGVSDLITHLDEINRLNVF
MAV_3819|M.avium_104 MAAQRRWVTLGSSWTSHDRPLDAAALRDWAHTAVSDLITHIDEINRLNVF
MAB_3279c|M.abscessus_ATCC_199 ---------------MRLSVLDSAALLDWARASVEGLISRSDEINRLNVF
**: :* **: * ** : ****:****
Mflv_4213|M.gilvum_PYR-GCK PVADADTGTNMLFTMRAAWAQADS-DAAD----------DVTAITAALAA
Mvan_2154|M.vanbaalenii_PYR-1 PVADADTGTNMLFTMRAAWAEADSCDAGD----------DVTAVAAALAG
MSMEG_2402|M.smegmatis_MC2_155 PVADADTGTNMLFTMRSAWAHADA-QSGG----------DVAQVASALAA
Rv2975c|M.tuberculosis_H37Rv PVADSDTGVNMLFTMRAAVVEADLHANSQAD------AEDVARVAAALAA
Mb2999c|M.bovis_AF2122/97 PVADSDTGVNMLFTMRAAVVEADLHANSQAD------AEDVARVAAALAA
MMAR_1741|M.marinum_M PVADSDTGANMLFTMRSALAQVDSTGGAGPEHPEDPEHRDVAQVAAALAA
MAV_3819|M.avium_104 PVADSDTGANMLFTMRSALAELQAAGGPG----------CVARAAAALST
MAB_3279c|M.abscessus_ATCC_199 PVADADTGTNMLFTMRSAVNAAEALGEGA----------TVAQVAAALAR
****:***.*******:* : *: ::**:
Mflv_4213|M.gilvum_PYR-GCK GALRGARGNSGVILSQILRALAEVTAEAAEERGGVLSEVTGEMLAAALRH
Mvan_2154|M.vanbaalenii_PYR-1 GALHGARGNSGVILSQILRAVAEVTASAAEDRDGVLADITGPLLSSALRH
MSMEG_2402|M.smegmatis_MC2_155 GALQGARGNSGVILSQILLGLAEVITSAAADRGGDLLDVDGPLFGAALRH
Rv2975c|M.tuberculosis_H37Rv GAR-----------------------------------------------
Mb2999c|M.bovis_AF2122/97 GALNGARGNSGVILSQILRGIAEVTATAAAASGAVLRAVDANALGAALWR
MMAR_1741|M.marinum_M GALNGARGNSGVILSQILRGVSDVTDSAAA--GQPLAAIDAALLAAALWR
MAV_3819|M.avium_104 GALNGARGNSGVILSQILRGVADVTATAAARAGGQLAHIEAAVLGAALQR
MAB_3279c|M.abscessus_ATCC_199 GAVHGARGNSGVILSQIVRGIADAAD--------DQDAIGAEVVRRALRQ
**
Mflv_4213|M.gilvum_PYR-GCK AVTLVVASMG-EAVPGTIVSVLHDAAAAAEDAVCGQADLAAVVVACTQAA
Mvan_2154|M.vanbaalenii_PYR-1 AVTLVVTSMG-EAVPGTIVSVLHDAAEAAEEAVSAEAELADVVAACAHAA
MSMEG_2402|M.smegmatis_MC2_155 GVALVAVSMG-DPVPGTIVTVLQAAADAAEKCVVGGADLAEVAASAADAA
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 GVELVVASMGGVEVPGTIVSVLRAAAGAVDQCA--HEGLAGAVTAAGDAA
MMAR_1741|M.marinum_M GVELVITSMGGEEVPGTIVSVLRAAAVAVRQCADAGEGLAAAVAAAGDAA
MAV_3819|M.avium_104 GVELVIASMGGEEIPGTIVSVLRAAATAVAQCARAGEGVTAAVIAAGDAA
MAB_3279c|M.abscessus_ATCC_199 ASQFVIASMS-TPVEGTIVSVLAAAADAADDAQ--SDDLPVLVTTAADAA
Mflv_4213|M.gilvum_PYR-GCK AAALDRTPTQLDVLADAGVVDAGGRGLLVLLDALSAILTGELTRRQVYLP
Mvan_2154|M.vanbaalenii_PYR-1 GAALDRTPTQLDVLADAGVVDAGGRGLVVLLDALCATLTGHAPRRGVYQP
MSMEG_2402|M.smegmatis_MC2_155 ATALERTPQQLDVLAEAGVVDSGGRGLLVLLDAMTATITGHAPRRPAYTP
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 VIALEKTPEQLDVLADAGAVDAGGRGLLVLLDALRSTICGQAPARAVYEP
MMAR_1741|M.marinum_M VVALEKTPEQLDVLADAGVVDAGGRGLLVLLDALRSTITGAAPARSVYEP
MAV_3819|M.avium_104 VIALEKTPEQLDVLADAGAVDAGGRGLLVLLDALRTTITGQAPARTVYRL
MAB_3279c|M.abscessus_ATCC_199 VSALEKTPKQLDVLADNGVVDAGARGLVVILDALVSVVAGELPSRREYSP
Mflv_4213|M.gilvum_PYR-GCK DPKHAAGA----AAP------------PSPTPGFEVMYLLSDCDAENVEQ
Mvan_2154|M.vanbaalenii_PYR-1 SPNKSSAP----SSA------------AHATPSFEVMYLLADCHAEDIEK
MSMEG_2402|M.smegmatis_MC2_155 APPRATAS----SSVSARAGVPADDVAPTQVPQFEVMYLLSGCAPEAVEH
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 SPRALPTD----TAT------------QRPAPQFEVMYLLAVCDAAAADQ
MMAR_1741|M.marinum_M APRSPALG----VGV------------PAPIPQFEVMYLLAGCDAAAADT
MAV_3819|M.avium_104 APRTAAPE----AAA------------PRPAPQFEVMYRLDDCAPAAADA
MAB_3279c|M.abscessus_ATCC_199 SPPKNAPSQVWVAGPGRGGGGLNLDPPRELPPEFEVMYLLCGCDELQIAD
Mflv_4213|M.gilvum_PYR-GCK LRARLDALGDSVAIAASGFGEAG---AGHYSVHVHADDAGAAVEAGLAVG
Mvan_2154|M.vanbaalenii_PYR-1 LRAALEELGDSIAIAASGFGEAGGAGPGHYSVHVHADDAGAAVEAGLAVG
MSMEG_2402|M.smegmatis_MC2_155 LRAGLEQIGESVAIATSGG--------DRYSVHVHVDDAGAAVEAGLAVG
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 LRDRLKELGESVAIAAAPP--------DSYSVHVHTDDAGAAVEAGLAVG
MMAR_1741|M.marinum_M LRDRLSELGDSVAIAAAPS--------ESYSVHVHTDDAGAAVEAGLAAG
MAV_3819|M.avium_104 LRDRLTELGDSVGIASAPSSAQ-----HTYSVHVHTDDAGAAVEAGLAAG
MAB_3279c|M.abscessus_ATCC_199 LRAQLDAMGDSIAIAGDGE--------MGHSVHAHVNDAGAAIEAGMKFG
Mflv_4213|M.gilvum_PYR-GCK TLSRIQITSLHGGADRSSAG---SWGRERAVLAVVDGEGAEELFVGEGAA
Mvan_2154|M.vanbaalenii_PYR-1 SLSRIQITSLSGGGDRHPAG---GWSRQRAVLAVVDGDGAESLFTGEGAE
MSMEG_2402|M.smegmatis_MC2_155 TLNRIQITALTGSGGSRPSG---GWERERAVLAVVDGDGGAELFAGEGAH
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 RVSRIVISALGSGTSGLPAG---GWTRGRAVLAVVDGDGAAELFAGEGAC
MMAR_1741|M.marinum_M RLSKIVISALSSGTTALAAG---GWTRQRAVLAVVDGDGAAELFAAEGAC
MAV_3819|M.avium_104 RLSRIVISALSSGGPGLPAG---GWTRERAVLAVVDGDGAAGLFSGEGAC
MAB_3279c|M.abscessus_ATCC_199 TPQSIQISSLRGGLDVPGGGHHDGRHRHRRVLALAEGDGAATLFSSEGAQ
Mflv_4213|M.gilvum_PYR-GCK VLRT-----EPGVEISAQQLLHALVKTGAAQVMVLPNGYVAAEEIVAGCA
Mvan_2154|M.vanbaalenii_PYR-1 ILRP-----QSDVPVSAQQLLHALVNTGAAQVMVLPNGYVAAEEIVAGCA
MSMEG_2402|M.smegmatis_MC2_155 VLRP-----EADEPVSAKQLLRALVDVGAAQVMVLPNGYVAAEELVAGCT
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 VLRPGPDAVTPAADISAHQLVRAVVDTGAAHVMVLPNGYVAAEELVAGCT
MMAR_1741|M.marinum_M VLRPGAGAAAPASDLSAHQLVRAVVDTGAAQVMVLPNGYVAVEELVAGCT
MAV_3819|M.avium_104 VLQRDPAAADPVTTISAHQLMRAVVDTGAAQVMVLPNGYVAAEELVAGCT
MAB_3279c|M.abscessus_ATCC_199 VLRVD------EPPASAKRLLDAVVDSGAHQIMVLPNGLMAAEELVAVCA
Mflv_4213|M.gilvum_PYR-GCK VAADWGIDLVPIPTGSMVQGLAALAVHDPGHRLVDDGYTMARAGAAARFG
Mvan_2154|M.vanbaalenii_PYR-1 VASDWGIDMVPVPTGSMVQGLAALAVHDPERRLVDDGYTMARAAAGARHG
MSMEG_2402|M.smegmatis_MC2_155 AAIGWGIDVVPVPAGSMVQGLAALAVHDAARQAVDDGYTMARAAAGARHG
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 AAIGWGVDVVPVPTGSMVQGLAALAVHDAARQAVDDGYSMARAAGASRHG
MMAR_1741|M.marinum_M AAIGWGVDVVPVPTGSMVQGLAALAVHDPASQAVDDGYIMARAAGAARHG
MAV_3819|M.avium_104 AAIGWGIDVVPIPTESMVQGLAALAVHDTGRQAVDDGYTMARAAGAARHG
MAB_3279c|M.abscessus_ATCC_199 AARGWGITVIPLPSASMAQGLAALAVHDPERMAVDDSYTMARAAGATRFG
Mflv_4213|M.gilvum_PYR-GCK SVRIAAEDALTWAGACRPGDGLGITGDEVVVVGDDIVSAATGLIDLLLAA
Mvan_2154|M.vanbaalenii_PYR-1 TVRVAAEEALTWAGACKPGDGLGIAGDEVVIVGADVVAAGAGLIDLMLAA
MSMEG_2402|M.smegmatis_MC2_155 SVRVATEEALTWAGACKPGDGLGIAGDEVLIVGPDVTAAAAGLIDLLLAA
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 SVRIATQKALTWAGTCKPGDGLGIAGDEVLIVADDVAAAAIGLVDLLLAS
MMAR_1741|M.marinum_M SVRIATETALTWAGTCKPGDGLGIAGDEVLIVADDVAAAAIGLVDLLLAP
MAV_3819|M.avium_104 SVRIATETALTWAGSCRPGDGLGIAGGEVLIVAADAVGAAIGLLDLLLAS
MAB_3279c|M.abscessus_ATCC_199 LVRVATERALTWSGTCEPGDAMGIIGDEVLVLNHDIANATKALVSIMLSS
Mflv_4213|M.gilvum_PYR-GCK GGELVTVLTGDGVES--------EVGAALAEHVHHNHLGAELVTFHTGHR
Mvan_2154|M.vanbaalenii_PYR-1 GGELVTVLTGDGVGP--------EIGEALAEHVHHHHPGTDLVTFHTGHR
MSMEG_2402|M.smegmatis_MC2_155 GGELITVLTGHGVDS--------AVGEALQAHVHDKHLGVELVTYHTGHR
Rv2975c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2999c|M.bovis_AF2122/97 GGDLVTVLIGAGVTED--------VAVVLERHVHDHHPGTELVSYRTGHR
MMAR_1741|M.marinum_M GGDLVTVLIGAGIDD---DERIARLVESLERHMHDHHPGTELVIYRTGHR
MAV_3819|M.avium_104 GGDLVTVLLGAGLDADGSDAHAGAVVDILEEHMHDHHPGTELVTYRTGHH
MAB_3279c|M.abscessus_ATCC_199 GGELVTVLLSDEVDD--------SLAESLIEHTRSHHGGVEVMIYRTGQH
Mflv_4213|M.gilvum_PYR-GCK ADALLIGVE
Mvan_2154|M.vanbaalenii_PYR-1 VDALVIGVE
MSMEG_2402|M.smegmatis_MC2_155 GDALLIGVE
Rv2975c|M.tuberculosis_H37Rv ---------
Mb2999c|M.bovis_AF2122/97 GDALLIGVE
MMAR_1741|M.marinum_M GDALLIGVE
MAV_3819|M.avium_104 GDVLLIGVE
MAB_3279c|M.abscessus_ATCC_199 TDVVHIGVE