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M. tuberculosis H37Rv Rv2965c (coaD)

annotation: phosphopantetheine adenylyltransferase
coordinates: 3318330 - 3318815
length: 161

TGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMFDLDERIAMVKESTTHLPNLRVQVGHG
LVVDFVRSCGMTAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVS
ELLPEPVNRRLRDRLNTERT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2965ccoaD-100% (161)phosphopantetheine adenylyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2989ccoaD5e-89100.00% (161) phosphopantetheine adenylyltransferase
M. gilvum PYR-GCKMflv_4196coaD3e-7180.77% (156) phosphopantetheine adenylyltransferase
M. leprae Br4923MLBr_01663coaD5e-7385.62% (153) phosphopantetheine adenylyltransferase
M. abscessus ATCC 19977MAB_3259ccoaD1e-6778.85% (156) phosphopantetheine adenylyltransferase
M. marinum MMMAR_1751coaD2e-7891.61% (155) phosphopantetheine adenylyltransferase KdtB
M. avium 104MAV_3810coaD5e-7991.08% (157) phosphopantetheine adenylyltransferase
M. smegmatis MC2 155MSMEG_2414coaD5e-7584.71% (157) phosphopantetheine adenylyltransferase
M. thermoresistible (build 8)TH_1227kdtB2e-7486.54% (156) PROBABLE PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE KDTB
M. ulcerans Agy99MUL_1994coaD1e-7891.61% (155) phosphopantetheine adenylyltransferase
M. vanbaalenii PYR-1Mvan_2167coaD8e-7282.05% (156) phosphopantetheine adenylyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4196|M.gilvum_PYR-GCK          MSGAVCPGSFDPVTLGHIDVFERAAAQFDEIVVAVMVNPNKSGMFTLDER
Mvan_2167|M.vanbaalenii_PYR-1       MSGAVCPGSFDPVTLGHIDIFERAAAQFDEVVVAVMVNPNKTGMFTHEER
Rv2965c|M.tuberculosis_H37Rv        MTGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMFDLDER
Mb2989c|M.bovis_AF2122/97           MTGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAILVNPAKTGMFDLDER
MMAR_1751|M.marinum_M               MTGAVCPGSFDPVTLGHVDVFERAAAQFDEVVVAILVNPAKKGMFDLDER
MUL_1994|M.ulcerans_Agy99           MTGAVCPGSFDPVTLGHVDVFERAAAQFDEVVVAILVNPAKKGMFDLDER
MLBr_01663|M.leprae_Br4923          ---MVCPGSFDPVTLGHIDVFERAAAQFDEVVVAILINPVKKGMFDLDER
MAV_3810|M.avium_104                MTGAVCPGSFDPVTLGHVDVFERASAQFDEVVVAILTNPAKKGMFDLDER
TH_1227|M.thermoresistible__bu      MSGAVCPGSFDPVTLGHVDVFERAAAQFDEVIVAVLVNPNKQGMFSLEER
MSMEG_2414|M.smegmatis_MC2_155      MSGAVCPGSFDPVTLGHIDVFERASAQFDEVVVAVLVNPNKKGMFDLDER
MAB_3259c|M.abscessus_ATCC_199      MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDER
                                        *************:*:****:*****::**:: ** * ***  :**

Mflv_4196|M.gilvum_PYR-GCK          IALIEESTTHLPNLRVESGQGLIVDFVRERGLTAIVKGLRTGTDFEYELQ
Mvan_2167|M.vanbaalenii_PYR-1       IALIEESTTHLPNLRVESGQGLIVDFVKARGLTAIVKGLRTGTDFEYELQ
Rv2965c|M.tuberculosis_H37Rv        IAMVKESTTHLPNLRVQVGHGLVVDFVRSCGMTAIVKGLRTGTDFEYELQ
Mb2989c|M.bovis_AF2122/97           IAMVKESTTHLPNLRVQVGHGLVVDFVRSCGMTAIVKGLRTGTDFEYELQ
MMAR_1751|M.marinum_M               IAMIEESTAHLPNLRVEAGQGLVVDFVKAQGMNAIVKGLRTGTDFEYELQ
MUL_1994|M.ulcerans_Agy99           IAMIEESTAHLPNLRVEAGQGLVVDFVKAQGMNAIVKGLRTGTDFEYELQ
MLBr_01663|M.leprae_Br4923          IAMINESTMHLPNLRVEAGEGLVVALVRSRGMTAIVKGLRTGVDFEYELQ
MAV_3810|M.avium_104                IAMIEESTTHLSNLRVEAGQGLVVDFVRSRGMTAIVKGLRTGTDFEYELQ
TH_1227|M.thermoresistible__bu      IEMIEESTTHLPNLRVESGSGLVVDFVKSRGMTAIVKGLRTGTDFEYELQ
MSMEG_2414|M.smegmatis_MC2_155      IAMIEESTTHLPNLRVESGQGLVVDFVKSRGLTAIVKGLRTGTDFEYELQ
MAB_3259c|M.abscessus_ATCC_199      IEMIRESTADLPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQ
                                    * ::.*** .*.****: * **:* :*:  *:.*********.*******

Mflv_4196|M.gilvum_PYR-GCK          MAQMNKHVAGIDTFFVATAPSYSFVSSSLAKEVAMLGGDVTALLPAAVNT
Mvan_2167|M.vanbaalenii_PYR-1       MAQMNNHIAGVDTFFIATTPRYSFVSSSLAKEVATLGGDVSELLPAPVNA
Rv2965c|M.tuberculosis_H37Rv        MAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNR
Mb2989c|M.bovis_AF2122/97           MAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNR
MMAR_1751|M.marinum_M               MAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNR
MUL_1994|M.ulcerans_Agy99           MAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNR
MLBr_01663|M.leprae_Br4923          MAQMNKHIAGVDTFFVATAPRYSFVSSSLVKEVAMLGGDVSELLPESVNR
MAV_3810|M.avium_104                MAQMNKHIAGVDTFFVATAPRYSFVSSSLAKEVAMLGGDVSELLPEPVNR
TH_1227|M.thermoresistible__bu      MAQMNKHIAGVDTFFVATTPRYSFVSSSLAKEVAMLGGDVSELLPGPVNA
MSMEG_2414|M.smegmatis_MC2_155      MAQMNKHVAGVDTFFVATTPQYSFVSSSLAKEVASLGGDVSALLPSPVNR
MAB_3259c|M.abscessus_ATCC_199      MAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQ
                                    *****:*:**:****:**:* ********.****  ****: *** .*: 

Mflv_4196|M.gilvum_PYR-GCK          RLTAKLAERG-
Mvan_2167|M.vanbaalenii_PYR-1       RLKAKLAARD-
Rv2965c|M.tuberculosis_H37Rv        RLRDRLNTERT
Mb2989c|M.bovis_AF2122/97           RLRDRLNTERT
MMAR_1751|M.marinum_M               RLRERTK----
MUL_1994|M.ulcerans_Agy99           RLRERTK----
MLBr_01663|M.leprae_Br4923          RFREKMSGTS-
MAV_3810|M.avium_104                RLREKLSGRS-
TH_1227|M.thermoresistible__bu      RLRKKLAERG-
MSMEG_2414|M.smegmatis_MC2_155      RLQEKLNG---
MAB_3259c|M.abscessus_ATCC_199      RLLGKLRGQAQ
                                    *:  :