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TKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPLVVAACVLGPGRIASLAALDDS KKLSEQAREKLFPLICRYAVAYHVVFIPSAEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLP MPSLPVIGGDAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYS FINVRRVASGSNTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2902c | rnhB | - | 100% (264) | ribonuclease HII |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2926c | rnhB | 1e-152 | 99.62% (264) | ribonuclease HII |
| M. gilvum PYR-GCK | Mflv_4168 | rnhB | 1e-102 | 81.58% (228) | ribonuclease HII |
| M. leprae Br4923 | MLBr_01611 | rnhB | 1e-104 | 76.73% (245) | ribonuclease HII |
| M. abscessus ATCC 19977 | MAB_3222c | rnhB | 5e-95 | 76.68% (223) | ribonuclease HII |
| M. marinum M | MMAR_1806 | rnhB | 1e-108 | 82.35% (238) | ribonuclease HII protein RnhB |
| M. avium 104 | MAV_3757 | rnhB | 1e-105 | 84.38% (224) | ribonuclease HII |
| M. smegmatis MC2 155 | MSMEG_2442 | rnhB | 1e-101 | 76.23% (244) | ribonuclease HII |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2054 | rnhB | 1e-108 | 82.35% (238) | ribonuclease HII |
| M. vanbaalenii PYR-1 | Mvan_2194 | rnhB | 1e-104 | 82.53% (229) | ribonuclease HII |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2902c|M.tuberculosis_H37Rv MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPL
Mb2926c|M.bovis_AF2122/97 MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPL
MMAR_1806|M.marinum_M MATTWPPRTVIRKSSGLR---TLESALQRSGLGPVAGVDEVGRGACAGPL
MUL_2054|M.ulcerans_Agy99 MATTWPPRTVIRKSSGLR---TLESALQRSGLGPVAGVDEVGRGACAGPL
MLBr_01611|M.leprae_Br4923 MATTWPPCRIIRKSGGLRGMWTLEYELQRSGLGPVAGVDEVGRGACAGPL
Mflv_4168|M.gilvum_PYR-GCK MPAVWPPRTVIRKSSGLR---TLESALYRAGLGPVAGVDEVGRGACAGPL
Mvan_2194|M.vanbaalenii_PYR-1 MPAAWPPRTVIRKSSGLR---TLESALYRAGLGPVAGVDEVGRGACAGPL
MAV_3757|M.avium_104 ---------MIRKSSGLR---TLESALYRSGLGPVAGVDEVGRGACAGPL
MSMEG_2442|M.smegmatis_MC2_155 MPGSWPPRTVIRKSSGLR---TLESALYRNGLGPVAGVDEVGRGACAGPL
MAB_3222c|M.abscessus_ATCC_199 MSTSWPPRTVIRKASGLR---TLELTLDRVGLGPVAGVDEAGRGACAGPL
:***:.*** *** * * **********.*********
Rv2902c|M.tuberculosis_H37Rv VVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPS
Mb2926c|M.bovis_AF2122/97 VVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPS
MMAR_1806|M.marinum_M VVAACALGPNRYESLAALDDSKKLTEKTREKLFPLICRYALAYHVVFIPS
MUL_2054|M.ulcerans_Agy99 VVAACALGPNRYESLAALDDSKKLTEKTREKLFPLICRYALAYHVVFIPS
MLBr_01611|M.leprae_Br4923 VVAACVLGPGRLE--ESLDDSKKLSAKGREMLFPLICRYALAYHVVFIPS
Mflv_4168|M.gilvum_PYR-GCK VVAACILGPNRLESLSALDDSKKLNESERERLFPLIRRYAVAFHVVFIPS
Mvan_2194|M.vanbaalenii_PYR-1 VVAACVLGPNRLESLAALDDSKKLNENERERLFPLIRRYALAYHVVFIPS
MAV_3757|M.avium_104 VVAACVLGPGKLESLAALDDSKKLTESVRERLFPVIRRYALAYHVVFIPP
MSMEG_2442|M.smegmatis_MC2_155 VVAACVLGPNRLESLAALDDSKKLGEKERERLFPLIRRYALAYHVVFIPS
MAB_3222c|M.abscessus_ATCC_199 VIAACVLGSNQRKSLAALNDSKKLTEKMRETLFPLICRYAEAYHVVSVPA
*:*** **..: :*:***** . ** ***:* *** *:*** :*.
Rv2902c|M.tuberculosis_H37Rv AEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGG
Mb2926c|M.bovis_AF2122/97 AEVDRHGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGG
MMAR_1806|M.marinum_M VEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MUL_2054|M.ulcerans_Agy99 VEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MLBr_01611|M.leprae_Br4923 VEVDRHGVQVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVVGG
Mflv_4168|M.gilvum_PYR-GCK VEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVVGG
Mvan_2194|M.vanbaalenii_PYR-1 QEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLPMPSLPVVGG
MAV_3757|M.avium_104 AEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGG
MSMEG_2442|M.smegmatis_MC2_155 HEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MAB_3222c|M.abscessus_ATCC_199 DEVDRIGVHVANIEGMRRAVAGLGVKPGYVLTDGFRVPGLPVPSLPVIGG
**** **:**************.::*****:********.:*****:**
Rv2902c|M.tuberculosis_H37Rv DAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALA
Mb2926c|M.bovis_AF2122/97 DAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALA
MMAR_1806|M.marinum_M DAAAACIAAASVLAKVSRDRLMVAMDTQYPGYGFAEHKGYSTRAHTLALT
MUL_2054|M.ulcerans_Agy99 DAAAACIAAASVLAKVSRDRLMVAMDTQYPGYGFAEHKGYSTRAHTLALT
MLBr_01611|M.leprae_Br4923 DAVVACIAAASVLAKVSRDRLMVAMDADYPGYGFAAHKGYCTRAHSLALT
Mflv_4168|M.gilvum_PYR-GCK DAAAACIAAASVLAKVSRDRLMVAMDQEHPGYGFADHKGYSTRAHSAALN
Mvan_2194|M.vanbaalenii_PYR-1 DAAAACIAAASVLAKVSRDRLMVAMEDEHPGYGFAEHKGYSTRAHSAALA
MAV_3757|M.avium_104 DAVAACIAAASVLAKVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALA
MSMEG_2442|M.smegmatis_MC2_155 DAAAACIAAASVLAKVSRDRLMVEMEEQHPGYGFAEHKGYITPAHTAALT
MAB_3222c|M.abscessus_ATCC_199 DASAACIAAASVLAKVSRDRVMVNMDSDHPGYGFAVHKGYSTAVHTEALR
** .****************:** :: ::****** **** * .*: **
Rv2902c|M.tuberculosis_H37Rv RLGPCPQHRYSFINVRRVASGSNTAEVADG-----QPDPRDGTAQTGEGR
Mb2926c|M.bovis_AF2122/97 RLGPCPQHRYSFINVRRVASGSNTAEVADG-----QPDPRDGTAQTGEGR
MMAR_1806|M.marinum_M QLGPCPEHRRSFINVRRVATRSNGAAAAER-----EADP---PQERDGTG
MUL_2054|M.ulcerans_Agy99 QLGPCPEHRRSFINVRRVATRSNGAATAER-----EADP---PQERDGTG
MLBr_01611|M.leprae_Br4923 QLGPCPEHRYSFINVRRIVTRSNTRAVAGF-----TPAP---PAEHGECR
Mflv_4168|M.gilvum_PYR-GCK DLGPSTQHRFSFINVRRLVVDGEPGQGGE--------------LECGKLA
Mvan_2194|M.vanbaalenii_PYR-1 RLGPSSQHRYSFINVRRLVMDGEPEEHGE--------------VGCGKML
MAV_3757|M.avium_104 RLGPCPQHRHSFINVRR-VANGS----G------------------GRVV
MSMEG_2442|M.smegmatis_MC2_155 RHGPCVEHRYSYVNVRRAAEATGVRWASDRVGVRWSTESAAETEEVRRAL
MAB_3222c|M.abscessus_ATCC_199 RLGPSAQHRQSFVNVRNAAMGSSLMRPLAP-------------RESDTGG
**. :** *::***. .
Rv2902c|M.tuberculosis_H37Rv WSKSSHPATMRATGRAQGT------
Mb2926c|M.bovis_AF2122/97 WSKSSHPATMRATGRAQGT------
MMAR_1806|M.marinum_M -------------------------
MUL_2054|M.ulcerans_Agy99 -------------------------
MLBr_01611|M.leprae_Br4923 -------------------------
Mflv_4168|M.gilvum_PYR-GCK VDVPVDMPVDRVLREGQLSR-----
Mvan_2194|M.vanbaalenii_PYR-1 VD----MPVDGVLHEGQLSR-----
MAV_3757|M.avium_104 ADCKPDLPLQR--DEGR--------
MSMEG_2442|M.smegmatis_MC2_155 EAFEVEWVTAPVEHEDAACAKMGSG
MAB_3222c|M.abscessus_ATCC_199 -------------------------