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M. leprae Br4923 MLBr_01611 (rnhB)

annotation: ribonuclease HII
coordinates: 1935364 - 1936086
length: 240

ATTWPPCRIIRKSGGLRGMWTLEYELQRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGRLEESLDDSKK
LSAKGREMLFPLICRYALAYHVVFIPSVEVDRHGVQVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVP
SLPVVGGDAVVACIAAASVLAKVSRDRLMVAMDADYPGYGFAAHKGYCTRAHSLALTQLGPCPEHRYSFI
NVRRIVTRSNTRAVAGFTPAPPAEHGECR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01611rnhB-100% (240)ribonuclease HII

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2926crnhB1e-10477.14% (245) ribonuclease HII
M. gilvum PYR-GCKMflv_4168rnhB2e-9277.63% (219) ribonuclease HII
M. tuberculosis H37RvRv2902crnhB1e-10376.73% (245) ribonuclease HII
M. abscessus ATCC 19977MAB_3222crnhB2e-8469.96% (223) ribonuclease HII
M. marinum MMMAR_1806rnhB1e-10581.86% (237) ribonuclease HII protein RnhB
M. avium 104MAV_3757rnhB3e-9576.39% (233) ribonuclease HII
M. smegmatis MC2 155MSMEG_2442rnhB1e-9277.48% (222) ribonuclease HII
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2054rnhB1e-10581.86% (237) ribonuclease HII
M. vanbaalenii PYR-1Mvan_2194rnhB3e-9373.75% (240) ribonuclease HII

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1806|M.marinum_M               MATTWPPRTVIRKSSGLR---TLESALQRSGLGPVAGVDEVGRGACAGPL
MUL_2054|M.ulcerans_Agy99           MATTWPPRTVIRKSSGLR---TLESALQRSGLGPVAGVDEVGRGACAGPL
MLBr_01611|M.leprae_Br4923          MATTWPPCRIIRKSGGLRGMWTLEYELQRSGLGPVAGVDEVGRGACAGPL
Mb2926c|M.bovis_AF2122/97           MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPL
Rv2902c|M.tuberculosis_H37Rv        MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPL
Mflv_4168|M.gilvum_PYR-GCK          MPAVWPPRTVIRKSSGLR---TLESALYRAGLGPVAGVDEVGRGACAGPL
Mvan_2194|M.vanbaalenii_PYR-1       MPAAWPPRTVIRKSSGLR---TLESALYRAGLGPVAGVDEVGRGACAGPL
MAV_3757|M.avium_104                ---------MIRKSSGLR---TLESALYRSGLGPVAGVDEVGRGACAGPL
MSMEG_2442|M.smegmatis_MC2_155      MPGSWPPRTVIRKSSGLR---TLESALYRNGLGPVAGVDEVGRGACAGPL
MAB_3222c|M.abscessus_ATCC_199      MSTSWPPRTVIRKASGLR---TLELTLDRVGLGPVAGVDEAGRGACAGPL
                                             :***:.***   ***  * * **********.*********

MMAR_1806|M.marinum_M               VVAACALGPNRYESLAALDDSKKLTEKTREKLFPLICRYALAYHVVFIPS
MUL_2054|M.ulcerans_Agy99           VVAACALGPNRYESLAALDDSKKLTEKTREKLFPLICRYALAYHVVFIPS
MLBr_01611|M.leprae_Br4923          VVAACVLGPGRLE--ESLDDSKKLSAKGREMLFPLICRYALAYHVVFIPS
Mb2926c|M.bovis_AF2122/97           VVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPS
Rv2902c|M.tuberculosis_H37Rv        VVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPS
Mflv_4168|M.gilvum_PYR-GCK          VVAACILGPNRLESLSALDDSKKLNESERERLFPLIRRYAVAFHVVFIPS
Mvan_2194|M.vanbaalenii_PYR-1       VVAACVLGPNRLESLAALDDSKKLNENERERLFPLIRRYALAYHVVFIPS
MAV_3757|M.avium_104                VVAACVLGPGKLESLAALDDSKKLTESVRERLFPVIRRYALAYHVVFIPP
MSMEG_2442|M.smegmatis_MC2_155      VVAACVLGPNRLESLAALDDSKKLGEKERERLFPLIRRYALAYHVVFIPS
MAB_3222c|M.abscessus_ATCC_199      VIAACVLGSNQRKSLAALNDSKKLTEKMRETLFPLICRYAEAYHVVSVPA
                                    *:*** **..:     :*:*****  . ** ***:* *** *:*** :*.

MMAR_1806|M.marinum_M               VEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MUL_2054|M.ulcerans_Agy99           VEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MLBr_01611|M.leprae_Br4923          VEVDRHGVQVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVVGG
Mb2926c|M.bovis_AF2122/97           AEVDRHGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGG
Rv2902c|M.tuberculosis_H37Rv        AEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGG
Mflv_4168|M.gilvum_PYR-GCK          VEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVVGG
Mvan_2194|M.vanbaalenii_PYR-1       QEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLPMPSLPVVGG
MAV_3757|M.avium_104                AEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGG
MSMEG_2442|M.smegmatis_MC2_155      HEVDRRGVHVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVIGG
MAB_3222c|M.abscessus_ATCC_199      DEVDRIGVHVANIEGMRRAVAGLGVKPGYVLTDGFRVPGLPVPSLPVIGG
                                     **** **:**************.::*****:********.:*****:**

MMAR_1806|M.marinum_M               DAAAACIAAASVLAKVSRDRLMVAMDTQYPGYGFAEHKGYSTRAHTLALT
MUL_2054|M.ulcerans_Agy99           DAAAACIAAASVLAKVSRDRLMVAMDTQYPGYGFAEHKGYSTRAHTLALT
MLBr_01611|M.leprae_Br4923          DAVVACIAAASVLAKVSRDRLMVAMDADYPGYGFAAHKGYCTRAHSLALT
Mb2926c|M.bovis_AF2122/97           DAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALA
Rv2902c|M.tuberculosis_H37Rv        DAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALA
Mflv_4168|M.gilvum_PYR-GCK          DAAAACIAAASVLAKVSRDRLMVAMDQEHPGYGFADHKGYSTRAHSAALN
Mvan_2194|M.vanbaalenii_PYR-1       DAAAACIAAASVLAKVSRDRLMVAMEDEHPGYGFAEHKGYSTRAHSAALA
MAV_3757|M.avium_104                DAVAACIAAASVLAKVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALA
MSMEG_2442|M.smegmatis_MC2_155      DAAAACIAAASVLAKVSRDRLMVEMEEQHPGYGFAEHKGYITPAHTAALT
MAB_3222c|M.abscessus_ATCC_199      DASAACIAAASVLAKVSRDRVMVNMDSDHPGYGFAVHKGYSTAVHTEALR
                                    ** .****************:** :: ::****** **** * .*: ** 

MMAR_1806|M.marinum_M               QLGPCPEHRRSFINVRRVATRSNGAAAAER-----EADP---PQERDGTG
MUL_2054|M.ulcerans_Agy99           QLGPCPEHRRSFINVRRVATRSNGAATAER-----EADP---PQERDGTG
MLBr_01611|M.leprae_Br4923          QLGPCPEHRYSFINVRRIVTRSNTRAVAGF-----TPAP---PAEHGECR
Mb2926c|M.bovis_AF2122/97           RLGPCPQHRYSFINVRRVASGSNTAEVADG-----QPDPRDGTAQTGEGR
Rv2902c|M.tuberculosis_H37Rv        RLGPCPQHRYSFINVRRVASGSNTAEVADG-----QPDPRDGTAQTGEGR
Mflv_4168|M.gilvum_PYR-GCK          DLGPSTQHRFSFINVRRLVVDGEPGQGGE--------------LECGKLA
Mvan_2194|M.vanbaalenii_PYR-1       RLGPSSQHRYSFINVRRLVMDGEPEEHGE--------------VGCGKML
MAV_3757|M.avium_104                RLGPCPQHRHSFINVRR-VANGS----G------------------GRVV
MSMEG_2442|M.smegmatis_MC2_155      RHGPCVEHRYSYVNVRRAAEATGVRWASDRVGVRWSTESAAETEEVRRAL
MAB_3222c|M.abscessus_ATCC_199      RLGPSAQHRQSFVNVRNAAMGSSLMRPLAP-------------RESDTGG
                                      **. :** *::***. .                               

MMAR_1806|M.marinum_M               -------------------------
MUL_2054|M.ulcerans_Agy99           -------------------------
MLBr_01611|M.leprae_Br4923          -------------------------
Mb2926c|M.bovis_AF2122/97           WSKSSHPATMRATGRAQGT------
Rv2902c|M.tuberculosis_H37Rv        WSKSSHPATMRATGRAQGT------
Mflv_4168|M.gilvum_PYR-GCK          VDVPVDMPVDRVLREGQLSR-----
Mvan_2194|M.vanbaalenii_PYR-1       VD----MPVDGVLHEGQLSR-----
MAV_3757|M.avium_104                ADCKPDLPLQR--DEGR--------
MSMEG_2442|M.smegmatis_MC2_155      EAFEVEWVTAPVEHEDAACAKMGSG
MAB_3222c|M.abscessus_ATCC_199      -------------------------