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MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLVEPARLSLGGKAFGIGVGLTA YTLGLRHAFDADHIAAIDNTTRKLMSDGHRPLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSST LHHYTGLIGTSISGAFLYLIGILNVIVLVGIVRVFAHLRRGDYDEAELEQQLDNRGLLIRFLGRFTKSLT KSWHMYPVGFLFGLGFDTATEIALLVLAGTSAAAGLPWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWA FSSPVRKIYYNITVTGLSVAVALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFALTWAI ALLVWHYGRVEERWTPAPDRTT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2856 | nicT | - | 100% (372) | POSSIBLE NICKEL-TRANSPORT INTEGRAL MEMBRANE PROTEIN NICT |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2881 | nicT | 0.0 | 100.00% (372) | nickel-transport integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1897c | - | 1e-110 | 55.39% (334) | high-affinity nickel-transporter NicT |
| M. marinum M | MMAR_1873 | hoxN | 1e-170 | 75.54% (372) | high-affinity nickel permease, HoxN |
| M. avium 104 | MAV_3711 | - | 1e-170 | 75.67% (374) | transition metal uptake transporter, Ni2+-Co2+ transporter |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2856|M.tuberculosis_H37Rv MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLV
Mb2881|M.bovis_AF2122/97 MASSQLDRQRSRSAKMNRALTAAEWWRLGLMFAVIVALHLVGWLTVTLLV
MAV_3711|M.avium_104 MTSTEIDRWPARATRFLGALAPAEWWRLASMLGAILALHLIGWLTLVLLV
MMAR_1873|M.marinum_M MASNDLVSRSSWWSRLHSTLTPPEWWRLGAMFAFIAALHVVGWGTLVFLV
MAB_1897c|M.abscessus_ATCC_199 ------------------------------MSVAVIALHVLGWGMLIFLV
* : ***::** : :**
Rv2856|M.tuberculosis_H37Rv EPARLSLGGKAFGIGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMSDGHR
Mb2881|M.bovis_AF2122/97 EPARLSLGGKAFGIGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMSDGHR
MAV_3711|M.avium_104 APAQYSLGGKAFGVGVGLTAYTLGLRHAFDADHIAAIDNTTRKLMNDGQR
MMAR_1873|M.marinum_M EPAQLAVGSRAFGIGIGVTAYTLGMRHAFDADHIAAIDNTTRKLMNDGQR
MAB_1897c|M.abscessus_ATCC_199 APAHFTVQGSVFGVGLGVTAYTLGMRHAFDADHIAAIDNTTRKLVADGRR
**: :: . .**:*:*:******:*******************: **:*
Rv2856|M.tuberculosis_H37Rv PLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGT
Mb2881|M.bovis_AF2122/97 PLAVGFFFSLGHSTVVFGLAVMLVTGLKAIVGPVENDSSTLHHYTGLIGT
MAV_3711|M.avium_104 PLAVGFFFSLGHSTVVFALAVLLACGVRTVVGPVRDDSSALHHYTGLIGT
MMAR_1873|M.marinum_M PLATGFFFSLGHSTVVFGLAVLLATGIKTIIGPVREDSSRLHHYTGLIGT
MAB_1897c|M.abscessus_ATCC_199 PMSVGFWFSLGHSSIVFIMVGLLALGVKTLAANVSDEHSSLQQWTGVFGT
*::.**:******::** :. :*. *:::: . * :: * *:::**::**
Rv2856|M.tuberculosis_H37Rv SISGAFLYLIGILNVIVLVGIVRVFAHLRRGDYD----EAELEQQLDNRG
Mb2881|M.bovis_AF2122/97 SISGAFLYLIGILNVIVLVGIVRVFAHLRRGDYD----EAELEQQLDNRG
MAV_3711|M.avium_104 SVSGVFLYAIALLNVVVLVGILRVLARVRRGDYDPHTDAAELERQLDNRG
MMAR_1873|M.marinum_M SVSGLFLYLIAILNVIILAGILRVFFRLRRGEFS----EAELEEQLNNRG
MAB_1897c|M.abscessus_ATCC_199 AVSGTFLLLIGLLNLISLIGIYRIAKRMRGGEVD----EAALERELSNRG
::** ** *.:**:: * ** *: ::* *: . * **.:*.***
Rv2856|M.tuberculosis_H37Rv LLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGTSAAAGL
Mb2881|M.bovis_AF2122/97 LLIRFLGRFTKSLTKSWHMYPVGFLFGLGFDTATEIALLVLAGTSAAAGL
MAV_3711|M.avium_104 LMNRWLGRFTKSITQSWHCYPVGLLFGLGFDTATEVALLVLAGTSAAAGL
MMAR_1873|M.marinum_M LINRLLGRFTNSITKSWHMYPVGLLFGLGFDTATEIALLVLAGTSAAAGL
MAB_1897c|M.abscessus_ATCC_199 GLNRLFGPLMAAIRKPWQMYPVGLLFGLGFDTVTEVSLLVIAGGAAVTGL
: * :* : :: :.*: ****:********.**::***:** :*.:**
Rv2856|M.tuberculosis_H37Rv PWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTG
Mb2881|M.bovis_AF2122/97 PWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSSPVRKIYYNITVTG
MAV_3711|M.avium_104 PWYAILCLPVLFAAGMCLLDTIDGSFMNFAYGWAFSNPVRKIYYNIIITA
MMAR_1873|M.marinum_M PWYAILCLPVLFTAGMCLLDTIDGSFMNFAYGWAFSNPVRKIYYNITITA
MAB_1897c|M.abscessus_ATCC_199 PWYAILVLPILFSAGMSLFDSLDGSLMNFAYDWAFQEPARKIYYNLVVTG
****** **:**:***.*:*::***:*****.***..*.******: :*.
Rv2856|M.tuberculosis_H37Rv LSVAVALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFAL
Mb2881|M.bovis_AF2122/97 LSVAVALLIGSVELLGLIANQLGWQGPFWDWLGGLDLNTVGFVVVAMFAL
MAV_3711|M.avium_104 LSVAVAWVIGSIELLVLFADEFGWRGSFWDWLGGLDLNTVGYVVVGMFVL
MMAR_1873|M.marinum_M LSVAVALLIGSVELLGLFADEFGWRGAFWDWIAGLNLNLVGFLVVGMFVV
MAB_1897c|M.abscessus_ATCC_199 LSVAVAVLIGSQEIISILTEKLDITSGPLAAVGELDLAAMGYVIVALFIV
****** :*** *:: ::::::. . :. *:* :*:::*.:* :
Rv2856|M.tuberculosis_H37Rv TWAIALLVWHYGRVEERWTPAPDRTT-----
Mb2881|M.bovis_AF2122/97 TWAIALLVWHYGRVEERWTPAPDRTT-----
MAV_3711|M.avium_104 TWAVALLIWRYGRIEERWAGADPRAGTGREA
MMAR_1873|M.marinum_M TWAAAMLVWRFGRIEEKWTAAANSAT-----
MAB_1897c|M.abscessus_ATCC_199 TWAAAALGWRYTGVRRRWGG-----------
*** * * *:: :..:*