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VTGWVPDVLPGYWQCTIPLGPDPDDEGDIVATLVGRGPQTGKARGDTTGAHHTVLAVHGYTDYFFHTELA DHFANRGFAFYALDLRKCGRSRAPGQTPHFITDLARYDTELEHSLSIINEQNRSAKVLVYGHSAGGLIVS LWLDRLRQRGEITRAGVTGLVLNSPFLDLQGPAILRLPLTSAFFAAMARMRPKWVARPPKEGGYGCTLHR DYDGEFDYNLQWKPVGGFPVTFGWIHASRRGHARLHRGIDVGVPNLILCSDHTVREKADPATLHRGDAVL DVTHITRWAGCIGNRSTVIAVADAKHDVFLSLPQPRQMAYRRLDLWLDDYLGTHNDTDASASSGKG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2854 | - | - | 100% (346) | hypothetical protein Rv2854 |
| M. tuberculosis H37Rv | Rv0183 | - | 8e-05 | 32.29% (96) | lysophospholipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2879 | - | 0.0 | 100.00% (346) | hypothetical protein Mb2879 |
| M. gilvum PYR-GCK | Mflv_4053 | - | 1e-131 | 69.79% (331) | hypothetical protein Mflv_4053 |
| M. leprae Br4923 | MLBr_02603 | - | 5e-07 | 33.33% (87) | hypothetical protein MLBr_02603 |
| M. abscessus ATCC 19977 | MAB_3160 | - | 1e-104 | 58.56% (333) | hypothetical protein MAB_3160 |
| M. marinum M | MMAR_1880 | - | 1e-135 | 69.34% (349) | hypothetical protein MMAR_1880 |
| M. avium 104 | MAV_3709 | - | 1e-139 | 70.93% (344) | hypothetical protein MAV_3709 |
| M. smegmatis MC2 155 | MSMEG_2612 | - | 1e-128 | 65.87% (334) | hypothetical protein MSMEG_2612 |
| M. thermoresistible (build 8) | TH_1388 | - | 1e-133 | 67.35% (343) | HYPOTHETICAL PROTEIN Rv2854 |
| M. ulcerans Agy99 | MUL_2108 | - | 1e-133 | 68.48% (349) | hypothetical protein MUL_2108 |
| M. vanbaalenii PYR-1 | Mvan_2299 | - | 1e-135 | 68.50% (346) | hypothetical protein Mvan_2299 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2854|M.tuberculosis_H37Rv MTG----WVPDVLPGYWQCTIPLGPDPDDEGDIVATLVGRGPQ-------
Mb2879|M.bovis_AF2122/97 MTG----WVPDVLPGYWQCTIPLGPDPDDEGDIVATLVGRGPQ-------
MAV_3709|M.avium_104 --------MPDVLPGYWQRTLALGADPAGEGDIVATLIRRGDD-------
Mflv_4053|M.gilvum_PYR-GCK MSG----WEPDPLPGYRQRTFALGPDPDGEGDLEATLVRRGDP-------
Mvan_2299|M.vanbaalenii_PYR-1 MSG----WEPDVLPGYWQCTFALGPDPDGEGELEATLVRRGDP-------
MSMEG_2612|M.smegmatis_MC2_155 MTSREPSWEPDVLPGFWQRTIDLGPDPDGEGDLFATLVRRGDP-------
TH_1388|M.thermoresistible__bu --------VSDVLPGYWQRTLHLGPDPDGEGDLVATLVRRGVPTTPAPTT
MAB_3160|M.abscessus_ATCC_1997 -----MTWEPDVLDGYLRQTIDLGIDPDGEGVITATLVRPEIQ-------
MMAR_1880|M.marinum_M MSG----WVPDVLPGYEQYTIPLGPDPVDEGDIVATLVRRANA-------
MUL_2108|M.ulcerans_Agy99 MSG----WVPDVLPGYEQYTIPFGPDPVDEGDIVATLVRRANA-------
MLBr_02603|M.leprae_Br4923 ----------MTITRTERNFYGVG----GVRIVYDVWMPDTRP-------
: : .* . : . :
Rv2854|M.tuberculosis_H37Rv ----------TGKARGDTTGAHHTVLAVHGYTDYFFH-TELADHFANRGF
Mb2879|M.bovis_AF2122/97 ----------TGKARGDTTGAHHTVLAVHGYTDYFFH-TELADHFANRGF
MAV_3709|M.avium_104 ----------AAPA------ADHAVLAVHGYTDYFFH-TALADHFAARGF
Mflv_4053|M.gilvum_PYR-GCK ---------------DTR--ARHAVLMVHGFTDYFFN-TELADHFASRGF
Mvan_2299|M.vanbaalenii_PYR-1 ---------------EPS--ARHAVLVVHGFTDYFFN-TELADRFAARGF
MSMEG_2612|M.smegmatis_MC2_155 ---------------ESTGRAEHAVLALHGYTDYFFN-TELADRFAAHGF
TH_1388|M.thermoresistible__bu PDATTPDPTTPDPRRATTRAAAEAVLLVHGYTDYFFH-TELADHFATRGF
MAB_3160|M.abscessus_ATCC_1997 ------------------PENGRAVLMVHGYTDYFFH-TELAEHFLARGY
MMAR_1880|M.marinum_M ------------------APSAHAVLAVHGFTDYFFN-TALADHFADRGF
MUL_2108|M.ulcerans_Agy99 ------------------APSAHAVLAVHGFTDYFFN-TALADHFADRGF
MLBr_02603|M.leprae_Br4923 ---------------------RAVIILAHGFGEHARRYDHVAHYFAAAGL
.:: **: :: . :*. * *
Rv2854|M.tuberculosis_H37Rv AFYALDLRKCGRSRAPGQTPHFITDLARYDTELEHSLSIIN----EQNRS
Mb2879|M.bovis_AF2122/97 AFYALDLRKCGRSRAPGQTPHFITDLARYDTELEHSLSIIN----EQNRS
MAV_3709|M.avium_104 AFYALDLHKCGRSRRDGQTPHFVTDLANYDTELERALSVAS----GGNR-
Mflv_4053|M.gilvum_PYR-GCK AFYALDLHKCGRSHRDGQTPHFTTDLARYDVELERALAVIA----EESA-
Mvan_2299|M.vanbaalenii_PYR-1 AFYALDLHKCGRSHREGQTPHFTTDLARYDVELERALDAIA----AVGP-
MSMEG_2612|M.smegmatis_MC2_155 AFYALDLDKCGRSRRDGQTPHFTTDLTRYDAELEQALSIIG----YDTAG
TH_1388|M.thermoresistible__bu VFYALDLHKCGRSRRPGQTPHFTTDLARYDADLNAALAVIA----DDNPG
MAB_3160|M.abscessus_ATCC_1997 RFFALDLRKCGRSRHEHQTPHYISDLSLYDAELNAAIAIINGEAGGGTSE
MMAR_1880|M.marinum_M VFYALDLQKCGRSHRPGQTPHFTTDLAQYDVELQRALAVIG-EHTGSAGA
MUL_2108|M.ulcerans_Agy99 AFYALDLQKCGRSHRPGQTPHFTTDLTQYDVELQRALAVIG-EHTGAADA
MLBr_02603|M.leprae_Br4923 ATYALDLRGHGRSAG---KRVLVRDLSEYNADFDILVGIAT----RDHPG
:**** *** . **: *:.::: :
Rv2854|M.tuberculosis_H37Rv AKVLVYGHSAGGLIVSLWLDRLRQRGEITRAGVTGLVLNSPFLDLQGPAI
Mb2879|M.bovis_AF2122/97 AKVLVYGHSAGGLIVSLWLDRLRQRGEITRAGVTGLVLNSPFLDLQGPAI
MAV_3709|M.avium_104 -RVLVYGHSAGGLIVSLWLDRLRRRNPVAHSAVGGLVLNSPFLELPGPPI
Mflv_4053|M.gilvum_PYR-GCK ARVLVYGHSAGGLVVSLWLDRLRARGATASAGVAGLVLNAPWLDLQGHAI
Mvan_2299|M.vanbaalenii_PYR-1 ARVLVYGHSAGGLVVSLWLDRLRARRATARKGVSGLVLNSPWLDLQGPAI
MSMEG_2612|M.smegmatis_MC2_155 ARVCLYGHSAGGLIVTLFADRMRRRNRQATHNITGLVLNSPFFDLHGPGI
TH_1388|M.thermoresistible__bu ARVLICGHSAGGLIVSLWLDRLRRRRSPLRHRIGGLVLNSPFLDLPGRPI
MAB_3160|M.abscessus_ATCC_1997 APILVYGHSAGGLIVSLWLNRLRVSDRLG--RIAGLILNSPWLDLQGRPF
MMAR_1880|M.marinum_M AKVLVYGHSAGGLIVSLWLDRLRRRRLGAHGGVGGLVLNSPWLDLQGAAV
MUL_2108|M.ulcerans_Agy99 AKVLVYGHSAGGLIVSLWLDRLRRRRLGAHGGVGGLVLNSPWLDLQGAAV
MLBr_02603|M.leprae_Br4923 LKRIVAGHSMGGAIVFAYGVERPD-------NYDLMVLSGPAVAAQDMVS
: *** ** :* : . ::*..* . .
Rv2854|M.tuberculosis_H37Rv LRLPLTSAFFAAMARMRPKWVARPPKEGG-YGCTLHRDYDGEFDYNLQWK
Mb2879|M.bovis_AF2122/97 LRLPLTSAFFAAMARMRPKWVARPPKEGG-YGCTLHRDYDGEFDYNLQWK
MAV_3709|M.avium_104 LRHSLTVALIAGLSRVRSKGVARSPVQGG-YGTTLHRDYGGEFDYNLQWK
Mflv_4053|M.gilvum_PYR-GCK LRTPPITAALRAMARTRKHSVVRRPNPGGGYGATLHRDYAGEFDYNLQWK
Mvan_2299|M.vanbaalenii_PYR-1 LRTPPTSVALMAMRRVRKHRVVRRPTEGG-YGTTLHRDYFGEFEYNLQWK
MSMEG_2612|M.smegmatis_MC2_155 LRTAPTSLTLRALARWRKHTVIRKPTVGG-YGTTLHRDYHGEFEYNLDWK
TH_1388|M.thermoresistible__bu LRAPVTTAAIGALARWRKLHVVRPPAEGG-YGTTLHRDYAGEFDYDLRWK
MAB_3160|M.abscessus_ATCC_1997 LRSGGTTAAVKAISRFRAKQAIPLPHEGA-YGASLHKDFHGEFDYNLEWK
MMAR_1880|M.marinum_M LRLGVISAAIGAVSRVRPMWVLRARGEPG-YGSGLHRDYHGEFDFNLQWK
MUL_2108|M.ulcerans_Agy99 LRLGVISNAIGAVSRVRPMWVLRARGEPG-YGSGLHRDYHGEFDFNLQWK
MLBr_02603|M.leprae_Br4923 PLRAVVGKGLGLVAPGLPVHQLEVDAISR--NRAVVAAYK---DDPLVYH
. : . : : : * ::
Rv2854|M.tuberculosis_H37Rv PVGGFPVTFGWIHASRRGHARLHRGIDVGVPNLILCSDHTVREKADPATL
Mb2879|M.bovis_AF2122/97 PVGGFPVTFGWIHASRRGHARLHRGIDVGVPNLILCSDHTVREKADPATL
MAV_3709|M.avium_104 PVGGFPITFGWLHAVRRGQARLHRGLDVGVPNLILRSDHSVQETPDPASM
Mflv_4053|M.gilvum_PYR-GCK PIGGFPVTVGWIHAIRRGQAALHRGLDVGVPNLILRSDHSVREAPDPELI
Mvan_2299|M.vanbaalenii_PYR-1 PVGGFPVTVGWIHAIRRAQSRLHRGLDVGVPNLILRSDRSVREVADPASI
MSMEG_2612|M.smegmatis_MC2_155 PVGGFPITLGWINAIRRGQAQLHRGLDVGVPNLILRSDHSVRETDDPEAI
TH_1388|M.thermoresistible__bu PIGGFPITAGWLYAVRRGHARLHRGLDVGVPNLILRSDHSVPEDAEPDRL
MAB_3160|M.abscessus_ATCC_1997 PVGGFPVRFGWISAIRRGHAELHRGLDVGVPNLILRSDRSLPGDIDPAVA
MMAR_1880|M.marinum_M PLGGFPVTAGWFSAIRRGQARLHRGLDVGVPNLILRSDHSVPDSADPTAV
MUL_2108|M.ulcerans_Agy99 PLGGFPVTAGWFSAIRRGQARLHRGLDVGVPNLILRSDHSVPDSADPTAV
MLBr_02603|M.leprae_Br4923 --GKVPAGVGRV-MLQVGETMTRRAPVLTTPLLVVHGSE-----------
* .* * . : ..: :*. : .* *:: ...
Rv2854|M.tuberculosis_H37Rv HRGDAVLDVTHITRWAGCIGNRSTVIAVADAKHDVFLSLPQPRQMAYRRL
Mb2879|M.bovis_AF2122/97 HRGDAVLDVTHITRWAGCIGNRSTVIAVADAKHDVFLSLPQPRQMAYRRL
MAV_3709|M.avium_104 HCGDAVLDVTQIARWAGCIGNRSTIIPVADAKHDVFLSLPGPRAAAYRQL
Mflv_4053|M.gilvum_PYR-GCK QRGDAVLDVAQIARWAGCIGNRSTIVPVVDAKHDVFLSLPGPRAAAYAEL
Mvan_2299|M.vanbaalenii_PYR-1 QRGDAVLDVAQIARWAGCIGNRTTVVPVTDAKHDVFLSLPEPRRAAYAEL
MSMEG_2612|M.smegmatis_MC2_155 QRGDAVLDVRQIARWAGCVGGRSTIVAIPDAKHDVFLSLAEPRAQAYREL
TH_1388|M.thermoresistible__bu QRGDAVLDVTQIARWAGCIGNRTTVIPIVDAKHDVFLSLPEPRRTAYREL
MAB_3160|M.abscessus_ATCC_1997 LQGDLVLDVQQIARWAGCIGNDQRVVPIPGAKHDVFLSVAQSRARAYREL
MMAR_1880|M.marinum_M ERGDAVLDVTQIARWAGCIGNRSTVIPVPDAKHDVFLSLPQPRLTAYRQL
MUL_2108|M.ulcerans_Agy99 ERGDAVLDVTQIARWAGCIGNRSTVIPVPDAKHDVFLSLPQPRLTAYRQL
MLBr_02603|M.leprae_Br4923 ---DRLVLVDGSHRLVECVGSTDVELKVYPGLYHEVFNEPE-RDQVLEDV
* :: * * . *:*. : : . :. .:. . * . :
Rv2854|M.tuberculosis_H37Rv DLWLDDYLG--THNDTD---ASASSGKG----
Mb2879|M.bovis_AF2122/97 DLWLDDYLG--THNDTD---ASASSGKG----
MAV_3709|M.avium_104 DLWLDGYLRDRSTESTR---APASRDEG----
Mflv_4053|M.gilvum_PYR-GCK DRWLDSYPAGSAAPSTPSEPPPSDGSTPHG--
Mvan_2299|M.vanbaalenii_PYR-1 DRWLDWYLAEASATS-----PQSDGGAGHG--
MSMEG_2612|M.smegmatis_MC2_155 DRWLDEYLSLQNPTQR----LVRDR-------
TH_1388|M.thermoresistible__bu DCWLDWYASQPVPGTLRSEPVPQVRPERGESA
MAB_3160|M.abscessus_ATCC_1997 NSWLQWYETAE---------------------
MMAR_1880|M.marinum_M DRWLDHYLETIDADPSK----PLRKG------
MUL_2108|M.ulcerans_Agy99 DRWLDHYLETIDADPSK----PLRKG------
MLBr_02603|M.leprae_Br4923 VCWILKRL------------------------
*: