For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SDLARTDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAAESSGPWNNAGTGHSALCEMNYTPEMP DGSIDITKAVRVNEQFQVTRQFWAYAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLF AGTEFIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCVQNGTTALFGHEVRNLS RQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGDTLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTAS HRAKVYGFPAPGAPPLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLSVLGVGL TERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQRVQVIRRDERNGGVLEFGTTVIGDADG SIAGLLGGSPGASTAVAIMLDVLQKCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLG AA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2852c | mqo | - | 100% (493) | malate:quinone oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2877c | mqo | 0.0 | 100.00% (493) | malate:quinone oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4052 | - | 0.0 | 70.20% (490) | malate:quinone oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3159c | - | 0.0 | 67.51% (474) | malate:quinone oxidoreductase |
| M. marinum M | MMAR_1881 | mqo | 0.0 | 79.72% (493) | malate:quinone oxidoreductase Mqo |
| M. avium 104 | MAV_3708 | mqo | 0.0 | 76.67% (493) | malate:quinone oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2613 | mqo | 0.0 | 71.60% (486) | malate:quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_1387 | - | 0.0 | 71.52% (474) | PROBABLE MALATE:QUINONE OXIDOREDUCTASE MQO (MALATE |
| M. ulcerans Agy99 | MUL_2109 | mqo | 0.0 | 79.31% (493) | malate:quinone oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2300 | - | 0.0 | 70.00% (490) | malate:quinone oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4052|M.gilvum_PYR-GCK MSEA-----EKTDVLLVGAGIMSATLCALLRLLEPNWSMTLVERLDGAAA
Mvan_2300|M.vanbaalenii_PYR-1 MSEP-----HKTDVLLVGAGIMSATLSALLRLVEPNWSMTLVERLDGAAA
TH_1387|M.thermoresistible__bu ---------------------MSATLGALLRLVEPNWSITLIERLDGAAA
MSMEG_2613|M.smegmatis_MC2_155 MSEANAGTNAKTDVVLVGAGIMSATLGTLIKLLEPNWSITMIERLDGAAA
MAB_3159c|M.abscessus_ATCC_199 ---------------------MSATLGALLRLVEPDLSITLIERLDAAAS
Rv2852c|M.tuberculosis_H37Rv MSDLAR-----TDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAA
Mb2877c|M.bovis_AF2122/97 MSDLAR-----TDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAA
MMAR_1881|M.marinum_M MSESAR-----TDVVLVGAGIMSATLGAMLRRLEPDWSITLIERLDAVAA
MUL_2109|M.ulcerans_Agy99 MSESAR-----TDVVLVGAGIMSATLGAMLRRLEPDWSITLIERLDAVAA
MAV_3708|M.avium_104 MSSLART--TRTDVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAA
***** .::: ::*: *:*::****..*:
Mflv_4052|M.gilvum_PYR-GCK ESSDPWNNAGTGHSALCELNYTPARPDGSIDIAKAVNVNEQFQVSRQFWT
Mvan_2300|M.vanbaalenii_PYR-1 ESSDPWNNAGTGHSALCELNYTPARPDGSIDITKAVSVNEQFQVSRQFWT
TH_1387|M.thermoresistible__bu ESSDPWNNAGTGHSALCELNYTPQRPDGSIDTTKAIHVNEQFQVSRQFWA
MSMEG_2613|M.smegmatis_MC2_155 ESSDPWNNAGTGHSALCELNYTPALPDGTIDISKAVNVNEQFQVSRQFWA
MAB_3159c|M.abscessus_ATCC_199 ESSDPWNNAGTGHSALCELNYTPQKADGSIDITKAITVNEQFQVSRQFWA
Rv2852c|M.tuberculosis_H37Rv ESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWA
Mb2877c|M.bovis_AF2122/97 ESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWA
MMAR_1881|M.marinum_M ESSGPWNNAGTGHSALCELNYTPQRPDGSIDISKAVRINEEFQVTRQFWA
MUL_2109|M.ulcerans_Agy99 ESSGPWNNAGTGHSALCELNYTPQRPDGSIDISKAVRINEEFQVTRQFWA
MAV_3708|M.avium_104 ESSSPWNNAGTGHSALCELNYTPQRADGSIDIAKAVRINEQFQVTRQFWA
***.**************:**** .**:** :**: :**:***:****:
Mflv_4052|M.gilvum_PYR-GCK YAVENGVLPDVRSFLNPIPHVSFVTGADNVQYLRKRYEALVGNPLFGTME
Mvan_2300|M.vanbaalenii_PYR-1 YAVENGVLPDVRSFLNPIPHVSFVTGADNVQYLRRRYDALVTNPLFATME
TH_1387|M.thermoresistible__bu YAVENGVLPDVRSFLNPIPHVSFVQGAENIDYLRRRYEALVTNPLFASME
MSMEG_2613|M.smegmatis_MC2_155 HAVENGVLPDVRSFLNPVPHVSFVYGADNVQYLKARYNALVTNPLFASME
MAB_3159c|M.abscessus_ATCC_199 YAVENGVLPDVRGFLNPIPHVSYVHGADKVEFLRKRHEALVGNPLFAKME
Rv2852c|M.tuberculosis_H37Rv YAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTE
Mb2877c|M.bovis_AF2122/97 YAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTE
MMAR_1881|M.marinum_M YAAENGILNDVRSFLNPLPHVSFVHGAERVHQLRRRRDALAGNPLFAGAE
MUL_2109|M.ulcerans_Agy99 YAAENGILNDVRSFLNPLPHVSFVHGAERVHQLRRRRDALAGNPLFAGAE
MAV_3708|M.avium_104 YAVEDGMLTD-RGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIE
:*.*:*:* * *.*:.*:**.*:* *: :. *: * .**. ****. *
Mflv_4052|M.gilvum_PYR-GCK FIDDAGEFARRLPLMAEGRDLREPVGLNWTQDGTDVDFGALSRQLLGFGA
Mvan_2300|M.vanbaalenii_PYR-1 YIDDSDEFARRLPLMAEKRDFSNPVGLNWTQDGTDVDFGSLSRQLLGFGA
TH_1387|M.thermoresistible__bu FIDDHDEFSRRLPLMAYQRDFSEPVALNWTQDGTDVDFGSLSRQLIAYVA
MSMEG_2613|M.smegmatis_MC2_155 FIDDKDEFTRRLPLMAEKRDFSEPVALNWSQHGTDVDFGSLSRQLIGFAA
MAB_3159c|M.abscessus_ATCC_199 FIDDDDEFARRLPLMAAGRDFTDPVGLNWSQDGTDVDFGELSKQLVGFGV
Rv2852c|M.tuberculosis_H37Rv FIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCV
Mb2877c|M.bovis_AF2122/97 FIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCV
MMAR_1881|M.marinum_M WIDDPDEFARRLPLMAAKRVFSEPIALNWAADGTDVDFGALSRQLIGYCV
MUL_2109|M.ulcerans_Agy99 WIDDPDEFARRLPLMAAKRVFSEPIALNWAADGTDVDFGALSRQLIGYCV
MAV_3708|M.avium_104 LIEDADEFARRLPLMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCV
*:. .**:****:** * : :* .***: .******* *::**:.: .
Mflv_4052|M.gilvum_PYR-GCK QQGMDTLFGHDVTNLSQNSDSTWTVKVVNRRTGRKRTFNAKFVFVGAGGG
Mvan_2300|M.vanbaalenii_PYR-1 KHGMTTLFGHEVVNLTQGSDGTWTVKIANRRTGQKRTINAKFVFVGAGGG
TH_1387|M.thermoresistible__bu EHGMTTMFGHEVRDLVKQRDGGWLVKVVNRRTGARRRIKAKFVFVGAGGG
MSMEG_2613|M.smegmatis_MC2_155 GNGMTTMFGHDVRDLSKNSDGSWTVKVRNRRTGNNFKINAKFVFVGAGGG
MAB_3159c|M.abscessus_ATCC_199 RSGTSAVFGTEVRNISRESDGGWLLKLVNGRTGEKRKLKAKFVFVGAGGG
Rv2852c|M.tuberculosis_H37Rv QNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGD
Mb2877c|M.bovis_AF2122/97 QNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGD
MMAR_1881|M.marinum_M RNGAVALFGQEVRNLVRQPDGGWMLTVVNRRTGEKRKLKTKFVFVGAGGN
MUL_2109|M.ulcerans_Agy99 RNGAVALFGQEVRNLVRQPDGGWMLTVVNRRTGEKRKLKTKFVFVGAGGN
MAV_3708|M.avium_104 RGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHRCNAKFVFVGAGGD
* ::** :* :: : *. * : : * *** . ::*********.
Mflv_4052|M.gilvum_PYR-GCK ALPLLQKAGIKEAKGFGGFPVGGQWLRTGNPELTAKHQAKVYGLPPLGAP
Mvan_2300|M.vanbaalenii_PYR-1 ALPLLQKAGIKEAKGFGGFPVGGQWLRTGNQDLTARHQAKVYGLPPLGAP
TH_1387|M.thermoresistible__bu ALPLLQKAGIPEVKGFGGFPVGGQFLRTNDPALTAAHKAKVYGLPPLGAP
MSMEG_2613|M.smegmatis_MC2_155 ALPLLQKSGIPEAKGFGGFPVGGAFLRTNKQHLTSRHNAKVYGLPPLGAP
MAB_3159c|M.abscessus_ATCC_199 ALGLLQKAGIPEAKGFGGFPVSGAFLRTNSTDLTDGHKAKVYGFPPLGAP
Rv2852c|M.tuberculosis_H37Rv TLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAP
Mb2877c|M.bovis_AF2122/97 TLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAP
MMAR_1881|M.marinum_M ALSLLQRSGIKEINGFAGFPIGGRFLRTANPALTAAHRAKVYGVPAPGAP
MUL_2109|M.ulcerans_Agy99 ALSLLQRSGIKEINGFAGFPIGGRFSRTANTALTAAHRAKVYGVPAPGAP
MAV_3708|M.avium_104 ALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTAAHRAKVYGAPAPGAP
:* :**::** * .**.***:.* : *: . ** *.***** *. ***
Mflv_4052|M.gilvum_PYR-GCK PMSVPHLDTRVINDKSWLLFGPFAGWSPKFLKQGKVTDLPFSVKPDNLVS
Mvan_2300|M.vanbaalenii_PYR-1 PMSVPHLDTRVINEKSWLLFGPFAGWSPKFLKQGKVTDLPFSVRPDNLVS
TH_1387|M.thermoresistible__bu PMSVPHLDARVINRKSWLLFGPFAGWSPKFLKHGKITDLPFSVKPNNLAS
MSMEG_2613|M.smegmatis_MC2_155 PMSVPHLDTRVINGRQWLLFGPFAGWSPKFLKQGKVTDLPLSVKPNNLAS
MAB_3159c|M.abscessus_ATCC_199 PMSAPHLDTRVINGKEWLLFGPFAGWSPKFLKMGKVTDLPASIKPNNLLS
Rv2852c|M.tuberculosis_H37Rv PLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLS
Mb2877c|M.bovis_AF2122/97 PLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLS
MMAR_1881|M.marinum_M PLGALHLDLRYVNGKSWLMFGPFAGWSPKFLKRGHLRDLPGSIKPNNILS
MUL_2109|M.ulcerans_Agy99 PLGALHLDLRYVNGKSWLMFGPFAGWSPKFLKRGHLRDLPGSIKPNNILS
MAV_3708|M.avium_104 PLGALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVA
*:.. *** * :* : **:***:********* *:. *** *::*.*: :
Mflv_4052|M.gilvum_PYR-GCK MLGVGLTEMGLLKYLIGQLLLSEAARVENLREFAPSAKDSDWELDIAGQR
Mvan_2300|M.vanbaalenii_PYR-1 MLGVGLTEMGLLKYLIGQLLLSESARVENLRDFAPSARDSDWELDIAGQR
TH_1387|M.thermoresistible__bu MIGVGLTEMGLLKYLIGQLLMSEADRVEALREFAPSARDSDWELDIAGQR
MSMEG_2613|M.smegmatis_MC2_155 MLGVGLTEVGLLKYLIGQLLLSEPARVETLREFAPSAVDSDWELDIAGQR
MAB_3159c|M.abscessus_ATCC_199 MVGVGLTEFKLATFLLSQLALTPDDRIDMLREFAPKAQRADWELITAGQR
Rv2852c|M.tuberculosis_H37Rv VLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQR
Mb2877c|M.bovis_AF2122/97 VLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQR
MMAR_1881|M.marinum_M MVGVGVTQVTLLNYLIGQLRLSEPDRVAVLRKFVPSAADSDWELIVAGQR
MUL_2109|M.ulcerans_Agy99 MVGVGVTQVTLLNYLIGQLRLSEPDRVAVLREFVPSAADSDWELIVAGQR
MAV_3708|M.avium_104 LLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQR
::***:*: * :*:.** :: *: **.*.*.* :**** ****
Mflv_4052|M.gilvum_PYR-GCK VQVIRKAKGKGGVLEFGTTVLSAADGSIAGLLGASPGASTAVPAMFDVMK
Mvan_2300|M.vanbaalenii_PYR-1 VQVIRKAKGKGGVLEFGTTVLAAADGSIAGLLGASPGASTAVPAMFDVMK
TH_1387|M.thermoresistible__bu VQVIRR-KGRGGVLEFGTTVLSAADGSIAGLLGASPGASTAVPAMIEVME
MSMEG_2613|M.smegmatis_MC2_155 VQVIRR-KGAGGVLEFGTTVLAAADGSIAGLLGASPGASTAVPAMLDVLQ
MAB_3159c|M.abscessus_ATCC_199 VQVIRPAKGKGGALEFGTMVLNSADGSIAGLLGASPGASTAVPAMLDVMQ
Rv2852c|M.tuberculosis_H37Rv VQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQ
Mb2877c|M.bovis_AF2122/97 VQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQ
MMAR_1881|M.marinum_M VQVIRRDKRKGGVLEFGTTVVGEADGSIAGLLGGSPGASTAVPIMLEVLQ
MUL_2109|M.ulcerans_Agy99 VQVIRRDKRKGGVLEFDTTVVGEADGSIAGLLGGSPGASTAVPIMLEVLQ
MAV_3708|M.avium_104 VQVIRRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQ
***** . **.*:*.* *: .*********.********. *::*::
Mflv_4052|M.gilvum_PYR-GCK RCFADRYPSWEPKLKEMVPSLGVTLSDEPKLFEEVWARGTKVLKLDKPAG
Mvan_2300|M.vanbaalenii_PYR-1 RCFSDRYPSWEPKLKEMVPSLGTALSDEPKLFEEVWAHGTAVLKLDKPAS
TH_1387|M.thermoresistible__bu RCFSDRYQSWLPKLKEMVPSLGVELSKEPALFREVWAHGTKVLKLDQPAS
MSMEG_2613|M.smegmatis_MC2_155 RCFADRYQAWTPKLKEMVPSLGTKLSDEPKLFEEVWSWGTKVLKLDVQAN
MAB_3159c|M.abscessus_ATCC_199 RCFPDRYSNWMPKLKEMIPSLGISLSDEPSLFGEVWDWGTRVLGLEQ---
Rv2852c|M.tuberculosis_H37Rv KCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA--
Mb2877c|M.bovis_AF2122/97 KCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA--
MMAR_1881|M.marinum_M RCFTHRYQSWLPALKEMVPSLGANLSEEPVLYDEVRSWSSRALQLDAS--
MUL_2109|M.ulcerans_Agy99 RCFTHRYQSWLPALKEMVPSLGANLSEEPVLYDEVRSWSSRALQLDASGA
MAV_3708|M.avium_104 RCFADRYRSWLPALKEMVPSLGVTLSDEPALYEEVYSWGTKILGLDELDE
:**..** * * ****:**** **.** *: ** .: * *
Mflv_4052|M.gilvum_PYR-GCK AIPATTDGQSTAGTEHTPTAATV---------------------------
Mvan_2300|M.vanbaalenii_PYR-1 SIPATTADESTAGTEHSPAAATV---------------------------
TH_1387|M.thermoresistible__bu GLPSSSTEP--AGTEHTPTAATG---------------------------
MSMEG_2613|M.smegmatis_MC2_155 ------------TAEAANAPATV---------------------------
MAB_3159c|M.abscessus_ATCC_199 --------------------------------------------------
Rv2852c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2877c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1881|M.marinum_M --------------------------------------------------
MUL_2109|M.ulcerans_Agy99 KRCAVSGPKTLTYQPFTNCSSCGSRCSWSSRPAAIRSWTAVICSPRPATS
MAV_3708|M.avium_104 ERPK----------------------------------------------
Mflv_4052|M.gilvum_PYR-GCK --------
Mvan_2300|M.vanbaalenii_PYR-1 --------
TH_1387|M.thermoresistible__bu --------
MSMEG_2613|M.smegmatis_MC2_155 --------
MAB_3159c|M.abscessus_ATCC_199 --------
Rv2852c|M.tuberculosis_H37Rv --------
Mb2877c|M.bovis_AF2122/97 --------
MMAR_1881|M.marinum_M --------
MUL_2109|M.ulcerans_Agy99 GWKPPMAK
MAV_3708|M.avium_104 --------