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SSLARTTRTDVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAAESSSPWNNAGTGHSALCELNYTP QRADGSIDIAKAVRINEQFQVTRQFWAYAVEDGMLTDRGFVTPIPHASFVRGARAVEYLRRRQQALAPNP LFAGIELIEDADEFARRLPLMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCVRGGATALFGHQVHN LTRESDGSWTLLIRNRRTGEKHRCNAKFVFVGAGGDALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLT AAHRAKVYGAPAPGAPPLGALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVALLGV GVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQRVQVIRRDRRRGGVLDFDTTVVAAG DGSIAGLLGGSPGASTAVPIMLDVLQRCFADRYRSWLPALKEMVPSLGVTLSDEPALYEEVYSWGTKILG LDELDEERPK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3708 | mqo | - | 100% (501) | malate:quinone oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2877c | mqo | 0.0 | 76.67% (493) | malate:quinone oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4052 | - | 0.0 | 68.90% (492) | malate:quinone oxidoreductase |
| M. tuberculosis H37Rv | Rv2852c | mqo | 0.0 | 76.67% (493) | malate:quinone oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3159c | - | 0.0 | 65.55% (476) | malate:quinone oxidoreductase |
| M. marinum M | MMAR_1881 | mqo | 0.0 | 75.76% (491) | malate:quinone oxidoreductase Mqo |
| M. smegmatis MC2 155 | MSMEG_2613 | mqo | 0.0 | 69.96% (486) | malate:quinone oxidoreductase |
| M. thermoresistible (build 8) | TH_1387 | - | 0.0 | 67.86% (476) | PROBABLE MALATE:QUINONE OXIDOREDUCTASE MQO (MALATE |
| M. ulcerans Agy99 | MUL_2109 | mqo | 0.0 | 75.05% (497) | malate:quinone oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2300 | - | 0.0 | 69.61% (487) | malate:quinone oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4052|M.gilvum_PYR-GCK MSEA-----EKTDVLLVGAGIMSATLCALLRLLEPNWSMTLVERLDGAAA
Mvan_2300|M.vanbaalenii_PYR-1 MSEP-----HKTDVLLVGAGIMSATLSALLRLVEPNWSMTLVERLDGAAA
TH_1387|M.thermoresistible__bu ---------------------MSATLGALLRLVEPNWSITLIERLDGAAA
MSMEG_2613|M.smegmatis_MC2_155 MSEANAGTNAKTDVVLVGAGIMSATLGTLIKLLEPNWSITMIERLDGAAA
MAB_3159c|M.abscessus_ATCC_199 ---------------------MSATLGALLRLVEPDLSITLIERLDAAAS
Mb2877c|M.bovis_AF2122/97 MSDLAR-----TDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAA
Rv2852c|M.tuberculosis_H37Rv MSDLAR-----TDVVLIGAGIMSATLGVLLRRLEPNWSITLIERLDAVAA
MMAR_1881|M.marinum_M MSESAR-----TDVVLVGAGIMSATLGAMLRRLEPDWSITLIERLDAVAA
MUL_2109|M.ulcerans_Agy99 MSESAR-----TDVVLVGAGIMSATLGAMLRRLEPDWSITLIERLDAVAA
MAV_3708|M.avium_104 MSSLART--TRTDVVLVGAGIMSATLGALLRRLQPDWSMTFVERLDAVAA
***** .::: ::*: *:*::****..*:
Mflv_4052|M.gilvum_PYR-GCK ESSDPWNNAGTGHSALCELNYTPARPDGSIDIAKAVNVNEQFQVSRQFWT
Mvan_2300|M.vanbaalenii_PYR-1 ESSDPWNNAGTGHSALCELNYTPARPDGSIDITKAVSVNEQFQVSRQFWT
TH_1387|M.thermoresistible__bu ESSDPWNNAGTGHSALCELNYTPQRPDGSIDTTKAIHVNEQFQVSRQFWA
MSMEG_2613|M.smegmatis_MC2_155 ESSDPWNNAGTGHSALCELNYTPALPDGTIDISKAVNVNEQFQVSRQFWA
MAB_3159c|M.abscessus_ATCC_199 ESSDPWNNAGTGHSALCELNYTPQKADGSIDITKAITVNEQFQVSRQFWA
Mb2877c|M.bovis_AF2122/97 ESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWA
Rv2852c|M.tuberculosis_H37Rv ESSGPWNNAGTGHSALCEMNYTPEMPDGSIDITKAVRVNEQFQVTRQFWA
MMAR_1881|M.marinum_M ESSGPWNNAGTGHSALCELNYTPQRPDGSIDISKAVRINEEFQVTRQFWA
MUL_2109|M.ulcerans_Agy99 ESSGPWNNAGTGHSALCELNYTPQRPDGSIDISKAVRINEEFQVTRQFWA
MAV_3708|M.avium_104 ESSSPWNNAGTGHSALCELNYTPQRADGSIDIAKAVRINEQFQVTRQFWA
***.**************:**** .**:** :**: :**:***:****:
Mflv_4052|M.gilvum_PYR-GCK YAVENGVLPDVRSFLNPIPHVSFVTGADNVQYLRKRYEALVGNPLFGTME
Mvan_2300|M.vanbaalenii_PYR-1 YAVENGVLPDVRSFLNPIPHVSFVTGADNVQYLRRRYDALVTNPLFATME
TH_1387|M.thermoresistible__bu YAVENGVLPDVRSFLNPIPHVSFVQGAENIDYLRRRYEALVTNPLFASME
MSMEG_2613|M.smegmatis_MC2_155 HAVENGVLPDVRSFLNPVPHVSFVYGADNVQYLKARYNALVTNPLFASME
MAB_3159c|M.abscessus_ATCC_199 YAVENGVLPDVRGFLNPIPHVSYVHGADKVEFLRKRHEALVGNPLFAKME
Mb2877c|M.bovis_AF2122/97 YAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTE
Rv2852c|M.tuberculosis_H37Rv YAAENGILTDVRSFLNPVPHVSFVHGSRGVEYLRRRQKALAGNPLFAGTE
MMAR_1881|M.marinum_M YAAENGILNDVRSFLNPLPHVSFVHGAERVHQLRRRRDALAGNPLFAGAE
MUL_2109|M.ulcerans_Agy99 YAAENGILNDVRSFLNPLPHVSFVHGAERVHQLRRRRDALAGNPLFAGAE
MAV_3708|M.avium_104 YAVEDGMLTD-RGFVTPIPHASFVRGARAVEYLRRRQQALAPNPLFAGIE
:*.*:*:* * *.*:.*:**.*:* *: :. *: * .**. ****. *
Mflv_4052|M.gilvum_PYR-GCK FIDDAGEFARRLPLMAEGRDLREPVGLNWTQDGTDVDFGALSRQLLGFGA
Mvan_2300|M.vanbaalenii_PYR-1 YIDDSDEFARRLPLMAEKRDFSNPVGLNWTQDGTDVDFGSLSRQLLGFGA
TH_1387|M.thermoresistible__bu FIDDHDEFSRRLPLMAYQRDFSEPVALNWTQDGTDVDFGSLSRQLIAYVA
MSMEG_2613|M.smegmatis_MC2_155 FIDDKDEFTRRLPLMAEKRDFSEPVALNWSQHGTDVDFGSLSRQLIGFAA
MAB_3159c|M.abscessus_ATCC_199 FIDDDDEFARRLPLMAAGRDFTDPVGLNWSQDGTDVDFGELSKQLVGFGV
Mb2877c|M.bovis_AF2122/97 FIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCV
Rv2852c|M.tuberculosis_H37Rv FIESPDEFARRLPFMAAKRAFSEPVALNWAADGTDVDFGALAKQLIGYCV
MMAR_1881|M.marinum_M WIDDPDEFARRLPLMAAKRVFSEPIALNWAADGTDVDFGALSRQLIGYCV
MUL_2109|M.ulcerans_Agy99 WIDDPDEFARRLPLMAAKRVFSEPIALNWAADGTDVDFGALSRQLIGYCV
MAV_3708|M.avium_104 LIEDADEFARRLPLMADRRDFSEPTALNWARHGTDVDFGALSRQLIGFCV
*:. .**:****:** * : :* .***: .******* *::**:.: .
Mflv_4052|M.gilvum_PYR-GCK QQGMDTLFGHDVTNLSQNSDSTWTVKVVNRRTGRKRTFNAKFVFVGAGGG
Mvan_2300|M.vanbaalenii_PYR-1 KHGMTTLFGHEVVNLTQGSDGTWTVKIANRRTGQKRTINAKFVFVGAGGG
TH_1387|M.thermoresistible__bu EHGMTTMFGHEVRDLVKQRDGGWLVKVVNRRTGARRRIKAKFVFVGAGGG
MSMEG_2613|M.smegmatis_MC2_155 GNGMTTMFGHDVRDLSKNSDGSWTVKVRNRRTGNNFKINAKFVFVGAGGG
MAB_3159c|M.abscessus_ATCC_199 RSGTSAVFGTEVRNISRESDGGWLLKLVNGRTGEKRKLKAKFVFVGAGGG
Mb2877c|M.bovis_AF2122/97 QNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGD
Rv2852c|M.tuberculosis_H37Rv QNGTTALFGHEVRNLSRQSDGSWTVTMCNRRTGEKRKLNTKFVFVGAGGD
MMAR_1881|M.marinum_M RNGAVALFGQEVRNLVRQPDGGWMLTVVNRRTGEKRKLKTKFVFVGAGGN
MUL_2109|M.ulcerans_Agy99 RNGAVALFGQEVRNLVRQPDGGWMLTVVNRRTGEKRKLKTKFVFVGAGGN
MAV_3708|M.avium_104 RGGATALFGHQVHNLTRESDGSWTLLIRNRRTGEKHRCNAKFVFVGAGGD
* ::** :* :: : *. * : : * *** . ::*********.
Mflv_4052|M.gilvum_PYR-GCK ALPLLQKAGIKEAKGFGGFPVGGQWLRTGNPELTAKHQAKVYGLPPLGAP
Mvan_2300|M.vanbaalenii_PYR-1 ALPLLQKAGIKEAKGFGGFPVGGQWLRTGNQDLTARHQAKVYGLPPLGAP
TH_1387|M.thermoresistible__bu ALPLLQKAGIPEVKGFGGFPVGGQFLRTNDPALTAAHKAKVYGLPPLGAP
MSMEG_2613|M.smegmatis_MC2_155 ALPLLQKSGIPEAKGFGGFPVGGAFLRTNKQHLTSRHNAKVYGLPPLGAP
MAB_3159c|M.abscessus_ATCC_199 ALGLLQKAGIPEAKGFGGFPVSGAFLRTNSTDLTDGHKAKVYGFPPLGAP
Mb2877c|M.bovis_AF2122/97 TLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAP
Rv2852c|M.tuberculosis_H37Rv TLPVLQKSGIKEVKGFAGFPIGGRFLRAGNPALTASHRAKVYGFPAPGAP
MMAR_1881|M.marinum_M ALSLLQRSGIKEINGFAGFPIGGRFLRTANPALTAAHRAKVYGVPAPGAP
MUL_2109|M.ulcerans_Agy99 ALSLLQRSGIKEINGFAGFPIGGRFSRTANTALTAAHRAKVYGVPAPGAP
MAV_3708|M.avium_104 ALPLLQKSGIGEARGFAGFPIGGRFLRADNPVLTAAHRAKVYGAPAPGAP
:* :**::** * .**.***:.* : *: . ** *.***** *. ***
Mflv_4052|M.gilvum_PYR-GCK PMSVPHLDTRVINDKSWLLFGPFAGWSPKFLKQGKVTDLPFSVKPDNLVS
Mvan_2300|M.vanbaalenii_PYR-1 PMSVPHLDTRVINEKSWLLFGPFAGWSPKFLKQGKVTDLPFSVRPDNLVS
TH_1387|M.thermoresistible__bu PMSVPHLDARVINRKSWLLFGPFAGWSPKFLKHGKITDLPFSVKPNNLAS
MSMEG_2613|M.smegmatis_MC2_155 PMSVPHLDTRVINGRQWLLFGPFAGWSPKFLKQGKVTDLPLSVKPNNLAS
MAB_3159c|M.abscessus_ATCC_199 PMSAPHLDTRVINGKEWLLFGPFAGWSPKFLKMGKVTDLPASIKPNNLLS
Mb2877c|M.bovis_AF2122/97 PLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLS
Rv2852c|M.tuberculosis_H37Rv PLGALHLDLRFVNGKSWLVFGPYAGWSPKFLKHGQISDLPRSIRPDNLLS
MMAR_1881|M.marinum_M PLGALHLDLRYVNGKSWLMFGPFAGWSPKFLKRGHLRDLPGSIKPNNILS
MUL_2109|M.ulcerans_Agy99 PLGALHLDLRYVNGKSWLMFGPFAGWSPKFLKRGHLRDLPGSIKPNNILS
MAV_3708|M.avium_104 PLGALHLDLRYVNGKPWLVFGPYAGWSPKFLKHGHFTDLPRSVRPHNLVA
*:.. *** * :* : **:***:********* *:. *** *::*.*: :
Mflv_4052|M.gilvum_PYR-GCK MLGVGLTEMGLLKYLIGQLLLSEAARVENLREFAPSAKDSDWELDIAGQR
Mvan_2300|M.vanbaalenii_PYR-1 MLGVGLTEMGLLKYLIGQLLLSESARVENLRDFAPSARDSDWELDIAGQR
TH_1387|M.thermoresistible__bu MIGVGLTEMGLLKYLIGQLLMSEADRVEALREFAPSARDSDWELDIAGQR
MSMEG_2613|M.smegmatis_MC2_155 MLGVGLTEVGLLKYLIGQLLLSEPARVETLREFAPSAVDSDWELDIAGQR
MAB_3159c|M.abscessus_ATCC_199 MVGVGLTEFKLATFLLSQLALTPDDRIDMLREFAPKAQRADWELITAGQR
Mb2877c|M.bovis_AF2122/97 VLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQR
Rv2852c|M.tuberculosis_H37Rv VLGVGLTERRLLNYLISQLRLSEPERVSALREFAPSAIDSDWELTIAGQR
MMAR_1881|M.marinum_M MVGVGVTQVTLLNYLIGQLRLSEPDRVAVLRKFVPSAADSDWELIVAGQR
MUL_2109|M.ulcerans_Agy99 MVGVGVTQVTLLNYLIGQLRLSEPDRVAVLREFVPSAADSDWELIVAGQR
MAV_3708|M.avium_104 LLGVGVTQLTLLRYLIGQLRLSAPDRMRMLREFAPTAVDSDWELTVAGQR
::***:*: * :*:.** :: *: **.*.*.* :**** ****
Mflv_4052|M.gilvum_PYR-GCK VQVIRKAKGKGGVLEFGTTVLSAADGSIAGLLGASPGASTAVPAMFDVMK
Mvan_2300|M.vanbaalenii_PYR-1 VQVIRKAKGKGGVLEFGTTVLAAADGSIAGLLGASPGASTAVPAMFDVMK
TH_1387|M.thermoresistible__bu VQVIRR-KGRGGVLEFGTTVLSAADGSIAGLLGASPGASTAVPAMIEVME
MSMEG_2613|M.smegmatis_MC2_155 VQVIRR-KGAGGVLEFGTTVLAAADGSIAGLLGASPGASTAVPAMLDVLQ
MAB_3159c|M.abscessus_ATCC_199 VQVIRPAKGKGGALEFGTMVLNSADGSIAGLLGASPGASTAVPAMLDVMQ
Mb2877c|M.bovis_AF2122/97 VQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQ
Rv2852c|M.tuberculosis_H37Rv VQVIRRDERNGGVLEFGTTVIGDADGSIAGLLGGSPGASTAVAIMLDVLQ
MMAR_1881|M.marinum_M VQVIRRDKRKGGVLEFGTTVVGEADGSIAGLLGGSPGASTAVPIMLEVLQ
MUL_2109|M.ulcerans_Agy99 VQVIRRDKRKGGVLEFDTTVVGEADGSIAGLLGGSPGASTAVPIMLEVLQ
MAV_3708|M.avium_104 VQVIRRDRRRGGVLDFDTTVVAAGDGSIAGLLGGSPGASTAVPIMLDVLQ
***** . **.*:*.* *: .*********.********. *::*::
Mflv_4052|M.gilvum_PYR-GCK RCFADRYPSWEPKLKEMVPSLGVTLSDEPKLFEEVWARGTKVLKLDKPAG
Mvan_2300|M.vanbaalenii_PYR-1 RCFSDRYPSWEPKLKEMVPSLGTALSDEPKLFEEVWAHGTAVLKLDKPAS
TH_1387|M.thermoresistible__bu RCFSDRYQSWLPKLKEMVPSLGVELSKEPALFREVWAHGTKVLKLDQPAS
MSMEG_2613|M.smegmatis_MC2_155 RCFADRYQAWTPKLKEMVPSLGTKLSDEPKLFEEVWSWGTKVLKLDVQAN
MAB_3159c|M.abscessus_ATCC_199 RCFPDRYSNWMPKLKEMIPSLGISLSDEPSLFGEVWDWGTRVLGLEQ---
Mb2877c|M.bovis_AF2122/97 KCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA--
Rv2852c|M.tuberculosis_H37Rv KCFANRYQSWLPTLKEMVPSLGVQLSNEPALFDEVWSWSTKALKLGAA--
MMAR_1881|M.marinum_M RCFTHRYQSWLPALKEMVPSLGANLSEEPVLYDEVRSWSSRALQLDAS--
MUL_2109|M.ulcerans_Agy99 RCFTHRYQSWLPALKEMVPSLGANLSEEPVLYDEVRSWSSRALQLDASGA
MAV_3708|M.avium_104 RCFADRYRSWLPALKEMVPSLGVTLSDEPALYEEVYSWGTKILGLDELDE
:**..** * * ****:**** **.** *: ** .: * *
Mflv_4052|M.gilvum_PYR-GCK AIPATTDGQSTAGTEHTPTAATV---------------------------
Mvan_2300|M.vanbaalenii_PYR-1 SIPATTADESTAGTEHSPAAATV---------------------------
TH_1387|M.thermoresistible__bu GLPSSSTEP--AGTEHTPTAATG---------------------------
MSMEG_2613|M.smegmatis_MC2_155 ------------TAEAANAPATV---------------------------
MAB_3159c|M.abscessus_ATCC_199 --------------------------------------------------
Mb2877c|M.bovis_AF2122/97 --------------------------------------------------
Rv2852c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1881|M.marinum_M --------------------------------------------------
MUL_2109|M.ulcerans_Agy99 KRCAVSGPKTLTYQPFTNCSSCGSRCSWSSRPAAIRSWTAVICSPRPATS
MAV_3708|M.avium_104 ERPK----------------------------------------------
Mflv_4052|M.gilvum_PYR-GCK --------
Mvan_2300|M.vanbaalenii_PYR-1 --------
TH_1387|M.thermoresistible__bu --------
MSMEG_2613|M.smegmatis_MC2_155 --------
MAB_3159c|M.abscessus_ATCC_199 --------
Mb2877c|M.bovis_AF2122/97 --------
Rv2852c|M.tuberculosis_H37Rv --------
MMAR_1881|M.marinum_M --------
MUL_2109|M.ulcerans_Agy99 GWKPPMAK
MAV_3708|M.avium_104 --------