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RRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARGVPAVLMTFDPHPMEVVYP GSHPAQLTTLTRRAELVQDLGIEVFLVMPFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAG NVDTLRRAGERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPHRVEGVVVRGEGR GAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVTGTVVPGERYQAAVSVGTNPTFSGRTRTVEAFV LDTTADLYGQHVALDFVGRIRGQKKFESVRQLVAAMGADTERARDLLSTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2786c | ribF | - | 100% (331) | bifunctional riboflavin kinase/FMN adenylyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2809c | ribF | 0.0 | 100.00% (331) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. gilvum PYR-GCK | Mflv_4025 | - | 1e-152 | 84.59% (305) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. leprae Br4923 | MLBr_00852 | ribF | 1e-168 | 87.46% (327) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. abscessus ATCC 19977 | MAB_3109c | - | 1e-151 | 78.88% (322) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. marinum M | MMAR_1921 | ribF | 1e-176 | 92.59% (324) | bifunctional fad synthetase/riboflavin biosynthesis protein |
| M. avium 104 | MAV_3678 | ribF | 1e-163 | 91.21% (307) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. smegmatis MC2 155 | MSMEG_2653 | ribF | 1e-167 | 88.79% (321) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. thermoresistible (build 8) | TH_1280 | ribF | 1e-162 | 84.16% (322) | PROBABLE BIFUNCTIONAL FAD SYNTHETASE/RIBOFLAVIN BIOSYNTHESIS |
| M. ulcerans Agy99 | MUL_2146 | ribF | 1e-176 | 92.28% (324) | bifunctional riboflavin kinase/FMN adenylyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2348 | - | 1e-167 | 87.58% (322) | bifunctional riboflavin kinase/FMN adenylyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2786c|M.tuberculosis_H37Rv -MRRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAG
Mb2809c|M.bovis_AF2122/97 -MRRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAG
MMAR_1921|M.marinum_M --------MQRWRGQDEIPTDWGRCVLTVGVFDGVHRGHAELIAHAVKAG
MUL_2146|M.ulcerans_Agy99 --------MQRWRGQDEIPTDWGRCVLTVGVFDGVHRGHAELIAHAVKAG
MAV_3678|M.avium_104 -------------------------MLTIGVFDGVHRGHAELIAHAVKAG
MLBr_00852|M.leprae_Br4923 MGSRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHTELIAHTVQTG
TH_1280|M.thermoresistible__bu --------VQRWRGQEEIPTDWGRCVLTIGVFDGVHRGHTELIGQAVKSG
Mflv_4025|M.gilvum_PYR-GCK -------------------------MVTIGVFDGVHRGHQELIGRAVKAG
Mvan_2348|M.vanbaalenii_PYR-1 --------MQRWRGQDEIPTDWGRCVVTIGVFDGVHRGHQELISRAVKAG
MSMEG_2653|M.smegmatis_MC2_155 --------MQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELINHAVKAG
MAB_3109c|M.abscessus_ATCC_199 --------MQRWRGQDEIPSDWGRCVLTIGVFDGVHRGHAELIGRAVKAA
::*:********** *** ::*::.
Rv2786c|M.tuberculosis_H37Rv RARGVPAVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVQDLGIEVFLVM
Mb2809c|M.bovis_AF2122/97 RARGVPAVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVQDLGIEVFLVM
MMAR_1921|M.marinum_M RARGVPTVMMTFDPHPMEVVYPGSHPAQLTTLTRRAELVEELGIDVFLVM
MUL_2146|M.ulcerans_Agy99 RARGVPTVMMTFDPHPMEVVYPGSHPAQLTTLTRRAELVEELGIDVFLVM
MAV_3678|M.avium_104 RARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVEELGIDVFLVM
MLBr_00852|M.leprae_Br4923 RARNVPTVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELIEELGIDVFLVM
TH_1280|M.thermoresistible__bu RARGVPTVVMTFDPHPMEVVFPGSHPAMLTTLTRRAELIEELGVDVFLVM
Mflv_4025|M.gilvum_PYR-GCK RSRGVPTVLMTFDPHPMEVVFPGSHPAQLTTLTRRAELVEEMGIDVFLVM
Mvan_2348|M.vanbaalenii_PYR-1 RSRGVPVVLMTFDPHPMEVVFPGSHPAQLTTLTRRAELVEELGIDVFLVM
MSMEG_2653|M.smegmatis_MC2_155 RARGVPVVLMTFDPHPMEVVFPGNHPAQLTTLTRRAELVEELGIDVFLVM
MAB_3109c|M.abscessus_ATCC_199 RELNLKSVLMTFDPHPMEVVFPGTHPAQLTTLTRRAELAEELGVDVFLVV
* .: *:***********:**.*** ********** :::*::****:
Rv2786c|M.tuberculosis_H37Rv PFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGNVDTLRRA
Mb2809c|M.bovis_AF2122/97 PFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGNVDTLRRA
MMAR_1921|M.marinum_M PFTTDFMKLTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGSVDTLRHA
MUL_2146|M.ulcerans_Agy99 PFTTDFMKLTPDRFIHELLFEHLHVVEVVVGENFTFGKKAAGSVDTLRHA
MAV_3678|M.avium_104 PFTTDFMKLTPDRYVHELLVENLHVVEVVVGENFTFGKKATGNVETLRRA
MLBr_00852|M.leprae_Br4923 PFTTDFMKLTPDRYVHELLVEHLHVVEVVVGENFTFGKKAAGNVIMLRRA
TH_1280|M.thermoresistible__bu PFTADFMKLTPERYVHELLVERLHVVEVVVGENFTFGKKAAGNVEMLRQA
Mflv_4025|M.gilvum_PYR-GCK PFTSDFMKLTPERYVHELLVERLHVVEVVVGDNFTFGKKAAGNVELLRKA
Mvan_2348|M.vanbaalenii_PYR-1 PFTSDFMKLTPERYIHELLVERLHVVEVLVGENFTFGKKAAGNVDLLRKA
MSMEG_2653|M.smegmatis_MC2_155 PFTSDFMKLTPERYIHELLVEHLHVVEVVVGENFTFGKKAAGNVDMLRKA
MAB_3109c|M.abscessus_ATCC_199 PFTPEFMKLSPERYVHELLVERLHVAEVVVGENFTFGKKAAGNVQMLKKA
***.:****:*:*::****.*.***.**:**:********:*.* *::*
Rv2786c|M.tuberculosis_H37Rv GERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPH
Mb2809c|M.bovis_AF2122/97 GERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPH
MMAR_1921|M.marinum_M GERFGFAVEAMSLVSEHHSNETVTFSSTYIRSCVDAGDVMAATEALGRPH
MUL_2146|M.ulcerans_Agy99 GERFGFAVEAMSLVSEHHSNETVTFSSTYIRSCVDAGDVMAATEALGRPH
MAV_3678|M.avium_104 GERFGFAVEAMSLLSEHHSNQTVTFSSTYIRSCVDAGDVVAAMEALGRPH
MLBr_00852|M.leprae_Br4923 GQRFGFAVGSMSLLSEHRGNETVAFSSTYIRSCVDAGDMMAATEALGRPH
TH_1280|M.thermoresistible__bu GERFGFAVTAMSLVSEQTDGQRVTYSSTYIRSCVDAGDVVAAAEALGRPH
Mflv_4025|M.gilvum_PYR-GCK GDRFGFAVDSLSLVAEHHRDETVTFSSTYIRSCVDAGDMVAAEEALGRPH
Mvan_2348|M.vanbaalenii_PYR-1 GERFGFAVDSLSLVAEHHQDETVAFSSTYIRSCVDAGDMVAAAEALGRPH
MSMEG_2653|M.smegmatis_MC2_155 GERFGFAVEAMSLVAEHHRNETVTFSSTYIRACVDAGDMVAAAEALGRPH
MAB_3109c|M.abscessus_ATCC_199 GERFGFKVDAVTLVTEH----AVTFSSTYIRSCVDAGDMVAATEALGRPH
*:**** * :::*::*: *::******:******::** *******
Rv2786c|M.tuberculosis_H37Rv RVEGVVVRGEGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
Mb2809c|M.bovis_AF2122/97 RVEGVVVRGEGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
MMAR_1921|M.marinum_M RVEGVVVRGYGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
MUL_2146|M.ulcerans_Agy99 RVEGVVVRGYGRGAELGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
MAV_3678|M.avium_104 RVEGVVVRGEGRGIQLGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
MLBr_00852|M.leprae_Br4923 RVEGMVVRGQGRGTELGFPTANVASPMYSATPADGVYAAWFTVLGHGPVT
TH_1280|M.thermoresistible__bu RVEGVVVRGDGRGRGLGFPTANVAPPMYSAIPADGVYAAWFTVLGHGPVT
Mflv_4025|M.gilvum_PYR-GCK RVEGVVVRGDGRGRDLGFPTANVAPPMYAAIPADGVYAAWFTVLGHGPVV
Mvan_2348|M.vanbaalenii_PYR-1 RVEGVVVRGDGRGRVLGFPTANVAPPMYSAIPADGVYAAWFTVLGHSPVV
MSMEG_2653|M.smegmatis_MC2_155 RVEGVVVRGDGRGRVLGFPTANVAPPMYSAIPADGVYAAWFTVLGQGPQV
MAB_3109c|M.abscessus_ATCC_199 RVEGVVVRGDGRGRELGFPTANVAPPMFSAIPADGVYAAWFTLLGHGPTM
****:**** *** *********.**::* ***********:**:.*
Rv2786c|M.tuberculosis_H37Rv GTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTTADLYGQHVALDFVG
Mb2809c|M.bovis_AF2122/97 GTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTTADLYGQHVALDFVG
MMAR_1921|M.marinum_M GAVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTAADLYGQHVALDFVA
MUL_2146|M.ulcerans_Agy99 GAVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTAADLYGQHVALDFVA
MAV_3678|M.avium_104 GTVIPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTQADLYGQHVALDFVA
MLBr_00852|M.leprae_Br4923 GTVVPGECYQAAVSVGTNPTFSGRTRTVEAFVLDAVADLYGQHVALDFVG
TH_1280|M.thermoresistible__bu GTVIPGERYRAAVSIGTNPTFSGRTRTVEAFVLDTEADLYGQHVALDFVA
Mflv_4025|M.gilvum_PYR-GCK GTVTPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTEADLYGQHVAVDFVA
Mvan_2348|M.vanbaalenii_PYR-1 GTVTPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTSADLYGQHVAVDFVA
MSMEG_2653|M.smegmatis_MC2_155 GTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTFADLYGQHVAVDFVS
MAB_3109c|M.abscessus_ATCC_199 GTVVPGERYQAAVSVGSNPTFSGKARTVEAFILDTTADLYGQHVAVDFVA
*:* *** *:****:*:******::******:**: *********:***.
Rv2786c|M.tuberculosis_H37Rv RIRGQKKFESVRQLVAAMGADTERARDLLSTG-
Mb2809c|M.bovis_AF2122/97 RIRGQKKFESVRQLVAAMGADTERARDLLSTG-
MMAR_1921|M.marinum_M RIRGQKKFASVPELVAEIGADTERTRVLLSTG-
MUL_2146|M.ulcerans_Agy99 RIRGQKKFASVPELVAEIGADTERTRVLLSTG-
MAV_3678|M.avium_104 RIRGQHKFDSVDDLVVAMGQDTERARQLLSAG-
MLBr_00852|M.leprae_Br4923 RIRGQRKFDSVADLVAEMEKDIDRARALLAD--
TH_1280|M.thermoresistible__bu RIRGQEKFDSVDDLIAAMRRDTEQAREILSR--
Mflv_4025|M.gilvum_PYR-GCK RLRGQEKFGSVADLITAMEGDTERARTILSAQ-
Mvan_2348|M.vanbaalenii_PYR-1 RLRGQEKFDSVADLVTAMGADTERARALLSAH-
MSMEG_2653|M.smegmatis_MC2_155 RIRGQEKFDSVDDLVVAMERDVERARTILRDSV
MAB_3109c|M.abscessus_ATCC_199 RIRSMEKFKSIDDLVVAMGKDAEKARTILARN-
*:*. .** *: :*:. : * :::* :*