For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTEVVIDFTHPDVVMGNLEFLIDNGIH AVVGTTGFTAERFQQVESWLVAKPNTSVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPS GTAARTAKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVLFGTEGETLTIRHDS LDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2773c | dapB | - | 100% (245) | dihydrodipicolinate reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2795c | dapB | 1e-136 | 99.18% (245) | dihydrodipicolinate reductase |
| M. gilvum PYR-GCK | Mflv_4013 | - | 1e-113 | 81.97% (244) | dihydrodipicolinate reductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3096c | - | 7e-99 | 75.10% (241) | dihydrodipicolinate reductase DapB |
| M. marinum M | MMAR_1938 | dapB | 1e-121 | 88.52% (244) | dihydrodipicolinate reductase DapB |
| M. avium 104 | MAV_3662 | dapB | 1e-125 | 91.39% (244) | dihydrodipicolinate reductase |
| M. smegmatis MC2 155 | MSMEG_2664 | dapB | 1e-116 | 84.84% (244) | dihydrodipicolinate reductase |
| M. thermoresistible (build 8) | TH_0697 | dapB | 1e-113 | 83.33% (240) | DIHYDRODIPICOLINATE REDUCTASE DAPB (DHPR) |
| M. ulcerans Agy99 | MUL_2164 | dapB | 1e-120 | 88.11% (244) | dihydrodipicolinate reductase |
| M. vanbaalenii PYR-1 | Mvan_2374 | - | 1e-113 | 81.97% (244) | dihydrodipicolinate reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2773c|M.tuberculosis_H37Rv ---MRVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTE
Mb2795c|M.bovis_AF2122/97 ---MRVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTE
MAV_3662|M.avium_104 ---MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTE
MMAR_1938|M.marinum_M ---MRVGVLGAKGKVGATMVSAVESAADLTLSAEVDAGDPLSTLTETNTE
MUL_2164|M.ulcerans_Agy99 ---MRVGVLGAKGKVGATMVSAVESAADLTLSAEVDAGDPLSTLTETNTE
MSMEG_2664|M.smegmatis_MC2_155 ---MRVGVLGARGKVGATMVAAVEAAEDLTFSAGVDAGDDLSLLTESKTE
Mflv_4013|M.gilvum_PYR-GCK ---MRVGVLGAKGKVGATMVAGVQAAEDLTFTTGIDAGDPLSALVDTDTE
Mvan_2374|M.vanbaalenii_PYR-1 ---MRVGVLGARGKVGATMVAGVEAADDLTFTTGVDAGDSLSALVDSDTE
TH_0697|M.thermoresistible__bu -------VLGAKGKVGATMVQAVQAADDLTLSAEVDAGDPISALVDTDTE
MAB_3096c|M.abscessus_ATCC_199 MTNIATGVLGAQGKVGQAMCQAVDSAADLDLVAAVDKNDSLEALTAAS--
****:**** :* .* :* ** : : :* .* :. *.
Rv2773c|M.tuberculosis_H37Rv VVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERFQQVESWLVAKPNT
Mb2795c|M.bovis_AF2122/97 VVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERFQQVESWLVAKPNT
MAV_3662|M.avium_104 AVIDFTHPDVVMGNLEFLVRNGIHAVVGTTGFTAERLAQVREWLVDSPGT
MMAR_1938|M.marinum_M AVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERVEQVQSWLAKKPST
MUL_2164|M.ulcerans_Agy99 AVIDFTHPDVVMGNLEFLIFNGIHAVVGTTGFTAERVEQVQSWLAKKPST
MSMEG_2664|M.smegmatis_MC2_155 VVIDFTHPDVVMDNLKFVIDNGIHAVVGTTGFTWERIEQVEAWVKAKPGA
Mflv_4013|M.gilvum_PYR-GCK VVIDFTHPDVVMDNLKFLIENGIHAVVGTTGFTDERLDQVRKWLEAKPDV
Mvan_2374|M.vanbaalenii_PYR-1 VVIDFTHPSVVMDNLKFLIDNGIHAVVGTTGFTDERLDQVREWLAATPGA
TH_0697|M.thermoresistible__bu VVIDFTHPDVVMDNLKFLIDNGIHAVVGTTGFTDERLDRVRDWLSAKPGV
MAB_3096c|M.abscessus_ATCC_199 VVIDFTHPDVVMDNLKFLIGKGIHAVVGTTGFTDERLDQVRSWLADSPGT
.*******.***.**:*:: :************ **. :*. *: .*..
Rv2773c|M.tuberculosis_H37Rv SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTAART
Mb2795c|M.bovis_AF2122/97 SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKAEAPSGTAART
MAV_3662|M.avium_104 SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTATRT
MMAR_1938|M.marinum_M AVLIAPNFAIGAVLSMHFAKQAAPFFDSAEIIELHHPQKADAPSGTATRT
MUL_2164|M.ulcerans_Agy99 AVLIAPNFAIGAVLSMHFAKQAAPFFDSAEIIELHHPQKADAPSGTATRT
MSMEG_2664|M.smegmatis_MC2_155 SVLIAPNFAIGAVLSMHFAKQAAKYFESVEIIELHHPHKADAPSGTAART
Mflv_4013|M.gilvum_PYR-GCK SVLIAPNFAIGAVLSMHFAQQAAKHFESVEVIELHHPHKADAPSGTAART
Mvan_2374|M.vanbaalenii_PYR-1 SVLIAPNFAIGAVLSMHFAQQAAKYFESVEVIELHHPHKADAPSGTAMRT
TH_0697|M.thermoresistible__bu GVLIAPNFAIGAVLCMQFARQAARFFESVEVIELHHPQKADAPSGTAART
MAB_3096c|M.abscessus_ATCC_199 GVLIAPNFAIGAVLSMKFAQQAARFFESVEIIELHHPNKADAPSGTATRT
.*************.*:**:*** .*:*.*:******:**:****** **
Rv2773c|M.tuberculosis_H37Rv AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
Mb2795c|M.bovis_AF2122/97 AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MAV_3662|M.avium_104 AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEIL
MMAR_1938|M.marinum_M AKLIAEAREGLAPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MUL_2164|M.ulcerans_Agy99 AKLIAEAREGLAPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MSMEG_2664|M.smegmatis_MC2_155 AKLIAEARKGLPPNPDATSTGLDGARGADVDGIPVHSVRLAGLVAHQEVL
Mflv_4013|M.gilvum_PYR-GCK ARLIAEARKGMPPNPDATSTGLEGARGADVDGVPVHSIRLAGLVAHQEVL
Mvan_2374|M.vanbaalenii_PYR-1 ARLIAEARKGMPPNPDATSTGLDGARGADVDGVPVHSVRLAGLVAHQEVL
TH_0697|M.thermoresistible__bu ARLIADARKGMPPNPDATSTALDGARGADVDGVPVHSVRLAGLVAHQEVL
MAB_3096c|M.abscessus_ATCC_199 ARLIAEARRGLPPSPDATSTGLEGARGADVDGVRVHAVRVSGLVAHQEVL
*:***:**.*:.*.******.* *********: **::*::*******:*
Rv2773c|M.tuberculosis_H37Rv FGTEGETLTIRHDSLDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH
Mb2795c|M.bovis_AF2122/97 FGTEGEILTIRHDSLDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH
MAV_3662|M.avium_104 FGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEPLLDLG
MMAR_1938|M.marinum_M FGTQGETLTIRHDSLDRTSFVPGVLLAVRRVRERPGLTIGIEPLLNLQ
MUL_2164|M.ulcerans_Agy99 FGTQGETLTIRHDSLDRTSFVPGVLLAVRRVRERPGLTIGIEPLLNLQ
MSMEG_2664|M.smegmatis_MC2_155 FGTQGETLTIRHDSLDRTSFVPGVLLAVRKISGLQGLTVGIEPLLDLS
Mflv_4013|M.gilvum_PYR-GCK FGTLGETLTIRHDSIDRTSFVPGVLLAVRKIRENPGLTIGIESLLDLA
Mvan_2374|M.vanbaalenii_PYR-1 FGTMGETLTIRHDSIDRTSFVPGVLLAVRKIRERPGLTIGIEPLLDLK
TH_0697|M.thermoresistible__bu FGTQGETLTIRHDSIDRTSFVPGVLLAVRNIARHPGLTIGIEPLLDLT
MAB_3096c|M.abscessus_ATCC_199 FGTTGETLTIRHDSIDRSSFAPGVLLAVRDIAKRPGLTIGIEPLLEL-
*** ** *:*****:**:**.******** : ***:*:*.**:*