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M. bovis AF2122 / 97 Mb2795c (dapB)

annotation: dihydrodipicolinate reductase
coordinates: 3038178 - 3038915
length: 245

MRVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTEVVIDFTHPDVVMGNLEFLIDNGI
HAVVGTTGFTAERFQQVESWLVAKPNTSVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKAEAP
SGTAARTAKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVLFGTEGEILTIRHD
SLDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2795cdapB-100% (245)dihydrodipicolinate reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_4013-1e-11281.15% (244) dihydrodipicolinate reductase
M. tuberculosis H37RvRv2773cdapB1e-13699.18% (245) dihydrodipicolinate reductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3096c-1e-9774.27% (241) dihydrodipicolinate reductase DapB
M. marinum MMMAR_1938dapB1e-12087.70% (244) dihydrodipicolinate reductase DapB
M. avium 104MAV_3662dapB1e-12490.57% (244) dihydrodipicolinate reductase
M. smegmatis MC2 155MSMEG_2664dapB1e-11584.02% (244) dihydrodipicolinate reductase
M. thermoresistible (build 8)TH_0697dapB1e-11282.50% (240) DIHYDRODIPICOLINATE REDUCTASE DAPB (DHPR)
M. ulcerans Agy99MUL_2164dapB1e-11987.30% (244) dihydrodipicolinate reductase
M. vanbaalenii PYR-1Mvan_2374-1e-11281.15% (244) dihydrodipicolinate reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2795c|M.bovis_AF2122/97           ---MRVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTE
Rv2773c|M.tuberculosis_H37Rv        ---MRVGVLGAKGKVGATMVRAVAAADDLTLSAELDAGDPLSLLTDGNTE
MAV_3662|M.avium_104                ---MRVGVLGAKGKVGSTMVAAVQAAEDLTLSAEVDAGDPLSLLTDGGTE
MMAR_1938|M.marinum_M               ---MRVGVLGAKGKVGATMVSAVESAADLTLSAEVDAGDPLSTLTETNTE
MUL_2164|M.ulcerans_Agy99           ---MRVGVLGAKGKVGATMVSAVESAADLTLSAEVDAGDPLSTLTETNTE
MSMEG_2664|M.smegmatis_MC2_155      ---MRVGVLGARGKVGATMVAAVEAAEDLTFSAGVDAGDDLSLLTESKTE
Mflv_4013|M.gilvum_PYR-GCK          ---MRVGVLGAKGKVGATMVAGVQAAEDLTFTTGIDAGDPLSALVDTDTE
Mvan_2374|M.vanbaalenii_PYR-1       ---MRVGVLGARGKVGATMVAGVEAADDLTFTTGVDAGDSLSALVDSDTE
TH_0697|M.thermoresistible__bu      -------VLGAKGKVGATMVQAVQAADDLTLSAEVDAGDPISALVDTDTE
MAB_3096c|M.abscessus_ATCC_199      MTNIATGVLGAQGKVGQAMCQAVDSAADLDLVAAVDKNDSLEALTAAS--
                                           ****:**** :*  .* :* ** : : :* .* :. *.     

Mb2795c|M.bovis_AF2122/97           VVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERFQQVESWLVAKPNT
Rv2773c|M.tuberculosis_H37Rv        VVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERFQQVESWLVAKPNT
MAV_3662|M.avium_104                AVIDFTHPDVVMGNLEFLVRNGIHAVVGTTGFTAERLAQVREWLVDSPGT
MMAR_1938|M.marinum_M               AVIDFTHPDVVMGNLEFLIDNGIHAVVGTTGFTAERVEQVQSWLAKKPST
MUL_2164|M.ulcerans_Agy99           AVIDFTHPDVVMGNLEFLIFNGIHAVVGTTGFTAERVEQVQSWLAKKPST
MSMEG_2664|M.smegmatis_MC2_155      VVIDFTHPDVVMDNLKFVIDNGIHAVVGTTGFTWERIEQVEAWVKAKPGA
Mflv_4013|M.gilvum_PYR-GCK          VVIDFTHPDVVMDNLKFLIENGIHAVVGTTGFTDERLDQVRKWLEAKPDV
Mvan_2374|M.vanbaalenii_PYR-1       VVIDFTHPSVVMDNLKFLIDNGIHAVVGTTGFTDERLDQVREWLAATPGA
TH_0697|M.thermoresistible__bu      VVIDFTHPDVVMDNLKFLIDNGIHAVVGTTGFTDERLDRVRDWLSAKPGV
MAB_3096c|M.abscessus_ATCC_199      VVIDFTHPDVVMDNLKFLIGKGIHAVVGTTGFTDERLDQVRSWLADSPGT
                                    .*******.***.**:*:: :************ **. :*. *:  .*..

Mb2795c|M.bovis_AF2122/97           SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKAEAPSGTAART
Rv2773c|M.tuberculosis_H37Rv        SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTAART
MAV_3662|M.avium_104                SVLIAPNFAIGAVLSMHFAKQAARFFDSAEVIELHHPHKADAPSGTATRT
MMAR_1938|M.marinum_M               AVLIAPNFAIGAVLSMHFAKQAAPFFDSAEIIELHHPQKADAPSGTATRT
MUL_2164|M.ulcerans_Agy99           AVLIAPNFAIGAVLSMHFAKQAAPFFDSAEIIELHHPQKADAPSGTATRT
MSMEG_2664|M.smegmatis_MC2_155      SVLIAPNFAIGAVLSMHFAKQAAKYFESVEIIELHHPHKADAPSGTAART
Mflv_4013|M.gilvum_PYR-GCK          SVLIAPNFAIGAVLSMHFAQQAAKHFESVEVIELHHPHKADAPSGTAART
Mvan_2374|M.vanbaalenii_PYR-1       SVLIAPNFAIGAVLSMHFAQQAAKYFESVEVIELHHPHKADAPSGTAMRT
TH_0697|M.thermoresistible__bu      GVLIAPNFAIGAVLCMQFARQAARFFESVEVIELHHPQKADAPSGTAART
MAB_3096c|M.abscessus_ATCC_199      GVLIAPNFAIGAVLSMKFAQQAARFFESVEIIELHHPNKADAPSGTATRT
                                    .*************.*:**:*** .*:*.*:******:**:****** **

Mb2795c|M.bovis_AF2122/97           AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
Rv2773c|M.tuberculosis_H37Rv        AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MAV_3662|M.avium_104                AKLIAEARKGLPPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEIL
MMAR_1938|M.marinum_M               AKLIAEAREGLAPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MUL_2164|M.ulcerans_Agy99           AKLIAEAREGLAPNPDATSTSLPGARGADVDGIPVHAVRLAGLVAHQEVL
MSMEG_2664|M.smegmatis_MC2_155      AKLIAEARKGLPPNPDATSTGLDGARGADVDGIPVHSVRLAGLVAHQEVL
Mflv_4013|M.gilvum_PYR-GCK          ARLIAEARKGMPPNPDATSTGLEGARGADVDGVPVHSIRLAGLVAHQEVL
Mvan_2374|M.vanbaalenii_PYR-1       ARLIAEARKGMPPNPDATSTGLDGARGADVDGVPVHSVRLAGLVAHQEVL
TH_0697|M.thermoresistible__bu      ARLIADARKGMPPNPDATSTALDGARGADVDGVPVHSVRLAGLVAHQEVL
MAB_3096c|M.abscessus_ATCC_199      ARLIAEARRGLPPSPDATSTGLEGARGADVDGVRVHAVRVSGLVAHQEVL
                                    *:***:**.*:.*.******.* *********: **::*::*******:*

Mb2795c|M.bovis_AF2122/97           FGTEGEILTIRHDSLDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH
Rv2773c|M.tuberculosis_H37Rv        FGTEGETLTIRHDSLDRTSFVPGVLLAVRRIAERPGLTVGLEPLLDLH
MAV_3662|M.avium_104                FGTEGETLSIRHDSLDRTSFVPGVLLAVRRIREHPGLTVGLEPLLDLG
MMAR_1938|M.marinum_M               FGTQGETLTIRHDSLDRTSFVPGVLLAVRRVRERPGLTIGIEPLLNLQ
MUL_2164|M.ulcerans_Agy99           FGTQGETLTIRHDSLDRTSFVPGVLLAVRRVRERPGLTIGIEPLLNLQ
MSMEG_2664|M.smegmatis_MC2_155      FGTQGETLTIRHDSLDRTSFVPGVLLAVRKISGLQGLTVGIEPLLDLS
Mflv_4013|M.gilvum_PYR-GCK          FGTLGETLTIRHDSIDRTSFVPGVLLAVRKIRENPGLTIGIESLLDLA
Mvan_2374|M.vanbaalenii_PYR-1       FGTMGETLTIRHDSIDRTSFVPGVLLAVRKIRERPGLTIGIEPLLDLK
TH_0697|M.thermoresistible__bu      FGTQGETLTIRHDSIDRTSFVPGVLLAVRNIARHPGLTIGIEPLLDLT
MAB_3096c|M.abscessus_ATCC_199      FGTTGETLTIRHDSIDRSSFAPGVLLAVRDIAKRPGLTIGIEPLLEL-
                                    *** ** *:*****:**:**.******** :    ***:*:*.**:*