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LGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVARSGTRTSRSKAT SRGASRSARSAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDI EPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPD SRPRLILGASLIGLSFLGLCHLWAGSPEAPESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLL LLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDGDDADTVEVARQDFSDGYYDEVPLCSDDGPPA WPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGA IGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKSAVGIE VPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLVS LLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDD FNDKVRSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPS VDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAV VTACKEQAEPEYTEGVTTAKPTAERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGR LMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGGE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2748c | ftsK | - | 100% (883) | POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK |
M. tuberculosis H37Rv | Rv3447c | - | 1e-16 | 26.45% (310) | hypothetical protein Rv3447c |
M. tuberculosis H37Rv | Rv3870 | - | 2e-15 | 26.27% (236) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2769c | ftsK | 0.0 | 100.00% (883) | cell division transmembrane protein FtsK |
M. gilvum PYR-GCK | Mflv_3994 | - | 0.0 | 73.29% (861) | cell divisionFtsK/SpoIIIE |
M. leprae Br4923 | MLBr_00977 | ftsK | 0.0 | 77.40% (885) | Cell division protein |
M. abscessus ATCC 19977 | MAB_3074c | - | 0.0 | 70.41% (838) | cell division protein FtsK |
M. marinum M | MMAR_1967 | ftsK | 0.0 | 82.42% (859) | cell division transmembrane protein FtsK |
M. avium 104 | MAV_3639 | - | 0.0 | 82.03% (768) | FtsK/SpoIIIE family protein |
M. smegmatis MC2 155 | MSMEG_2690 | - | 0.0 | 72.52% (888) | DNA translocase FtsK |
M. thermoresistible (build 8) | TH_0579 | ftsK | 0.0 | 75.82% (794) | POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK |
M. ulcerans Agy99 | MUL_3390 | ftsK | 0.0 | 82.04% (874) | cell division transmembrane protein FtsK |
M. vanbaalenii PYR-1 | Mvan_2393 | - | 0.0 | 73.50% (883) | cell divisionFtsK/SpoIIIE |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3994|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_2393|M.vanbaalenii_PYR-1 -------------------------------------MADGASEAFATRL MSMEG_2690|M.smegmatis_MC2_155 --MLIQRSLDGCPAYRENPFPNRFVPLSCYRYQAVTCVADGDSGADATRL TH_0579|M.thermoresistible__bu -------------------------------------------------- Rv2748c|M.tuberculosis_H37Rv MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRL Mb2769c|M.bovis_AF2122/97 MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRL MMAR_1967|M.marinum_M -------------------------------------------------- MUL_3390|M.ulcerans_Agy99 -------------------------------------MASGADDAIATSL MLBr_00977|M.leprae_Br4923 ------MIRVIRSSFYPRMLTIDLDAWEETKKQSIASVACSADDIIAIRL MAV_3639|M.avium_104 -------------------------------------------------- MAB_3074c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_3994|M.gilvum_PYR-GCK --MASKTAARSSAR----QTRSKPAPRGGGRS-ARPAAPRRKPA------ Mvan_2393|M.vanbaalenii_PYR-1 TPMASKTAARSAAR----QTRSKAPSRGGARP-ARPAARR---------- MSMEG_2690|M.smegmatis_MC2_155 ADMANKTAARSRARSESSSSRSSGRSRGGAKQGAQDGARRKPPTRP---- TH_0579|M.thermoresistible__bu -------------------------------------------------- Rv2748c|M.tuberculosis_H37Rv AVMSSKTVARSGTRTSRSKATSRGASRSARSAVPRKRSRPVKG------- Mb2769c|M.bovis_AF2122/97 AVMSSKTVARSGTRTSRSKATSRGASRSARSAVPRKRSRPVKG------- MMAR_1967|M.marinum_M --MASKTAARSGARTGRSKAASGGASRGGRATASAGPARPAKGTRKPAGK MUL_3390|M.ulcerans_Agy99 AGMASKTAARSGARTSRSKAASGGASRGGRATASAGPARPAKGTRKPAGK MLBr_00977|M.leprae_Br4923 VAMASKTVARSGNRTSSLKATSRGVSQSRRPVPP----RPRRN------- MAV_3639|M.avium_104 -------------------------------------------------- MAB_3074c|M.abscessus_ATCC_199 --MASKTVSRSRSRNTKPGPRSRNTAPTRRPAPRRRNQRR---------- Mflv_3994|M.gilvum_PYR-GCK ----PRKPARR-NSSAISTAGTAVGKGVRAGWLMVAKGAGSTARSVGRAR Mvan_2393|M.vanbaalenii_PYR-1 ------KPARR-HPSPVAAAGTAVGRGMRAGWLMLAKGAGSTARSVGRAR MSMEG_2690|M.smegmatis_MC2_155 APQQRRKPARRPQASPVALAGHKLGQGARAGWLMLAKGAGSTARSVGRAR TH_0579|M.thermoresistible__bu ---------------------------------MVAKGVGSAARSVGRAR Rv2748c|M.tuberculosis_H37Rv ----VGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRAR Mb2769c|M.bovis_AF2122/97 ----VGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRAR MMAR_1967|M.marinum_M PAKRVAKPIPRRNQSVLKVAGLAGGRAMRATWMMAAKGTGGAARSIGRAR MUL_3390|M.ulcerans_Agy99 PAKRVAKPIPRRNQSVLKVAGLAGGRAMRATWMMAAKGTGGAARSIGRAR MLBr_00977|M.leprae_Br4923 ------RPAERRNQSLLLAAGLTCGQAIRATWLVAAKGAGGAARSIGRAR MAV_3639|M.avium_104 --------------------------------MLAARGTGGAARSIGRAR MAB_3074c|M.abscessus_ATCC_199 -------------NQHWTAPLAALGRGARTGWHACAHGVGSLFRSVGRAH *:*.*. **:***: Mflv_3994|M.gilvum_PYR-GCK ELEPGHRRDGIALALLGLAVIVAASSWFDAARPVGAWIDTTVRVLIGAAV Mvan_2393|M.vanbaalenii_PYR-1 ELEPGHRRDGIALALLGLAVVVAASSWFDAARPVGAWIDTTVRIVIGSAV MSMEG_2690|M.smegmatis_MC2_155 DIEPGHRRDGIALALLGIAVVVAASSWFDAARPVGEWIDTALRTLVGGPV TH_0579|M.thermoresistible__bu DIDPGHRRDGIALVLLAVAVVVAASSWFDAARPVGEWLDTVLRMVIGSAV Rv2748c|M.tuberculosis_H37Rv DIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAV Mb2769c|M.bovis_AF2122/97 DIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAV MMAR_1967|M.marinum_M DIEPGHRRDGVALVVLGIAVVVAASSWFDAARPVGAWVDAVLRTFIGSAV MUL_3390|M.ulcerans_Agy99 DIEPGHRRDGVALVVLGIAVVVAASSWFDAARPVGAWVDAVLRTFIGSAV MLBr_00977|M.leprae_Br4923 DIEPGHRRDGIALALLGLAVVVAASSWFDAARPIGAWVDAVLRTFIGSAV MAV_3639|M.avium_104 DIDPGHRRDGIALLLLGFSVVVAASSWFHAAGPVGAWVDTALRTFIGAGV MAB_3074c|M.abscessus_ATCC_199 DIEHGHRRDGVALALLGVAFVVGASSWFHAAKPVGGWIDNAFRVVVGSGV ::: ******:** :*..:.:*.*****.** *:* *:* .* .:*. * Mflv_3994|M.gilvum_PYR-GCK VLVPVLLAVVGVTLMRSEPDPEARPRLILGSAMVALPAFGLWHLWAGAPA Mvan_2393|M.vanbaalenii_PYR-1 VLVPIVLATIGVILMRSEPDPESRPRLILGFAMVALPALGLWHLWSGAPQ MSMEG_2690|M.smegmatis_MC2_155 VLVPVLLAAIAVVLMRSEPDPEARPRLILGTAMIALPALGLWHLWAGSPT TH_0579|M.thermoresistible__bu VLVPIVVGGIAVVLMRSEPDPDTRPRLILGATMIALPVLGLWHLWSGAPD Rv2748c|M.tuberculosis_H37Rv VMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPE Mb2769c|M.bovis_AF2122/97 VMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPE MMAR_1967|M.marinum_M VLLPIVLAGTAIVLMRTEPNPDTRPRLILGSSLIALSFLGLRHLWAGSPE MUL_3390|M.ulcerans_Agy99 VLLPIVLAGTAIVLMRTESNPDTRPRLILGSSLIALSFLGLRHLWAGSPE MLBr_00977|M.leprae_Br4923 VVLPLVIAAVAVVLMRTQPNLDTRPRLILGATLIALSFLGLRHLWSGSPE MAV_3639|M.avium_104 LALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPG MAB_3074c|M.abscessus_ATCC_199 ALVPIIALVIAVFLMRTEPNPEERPRLLLGFAMVALPILGLWHLFAGSPD :*:: .: ***:..: : ****:** ::.*. :** **::*:* Mflv_3994|M.gilvum_PYR-GCK DPVERRHAGGFLGFALGGPLSDGLTAWIAAPLLFIGVLFGVLLLTGTTIR Mvan_2393|M.vanbaalenii_PYR-1 DPTARQHAAGFVGFVVGGPLSDGVTPWIAAPLLFIGVLFGLLLVTGTTIR MSMEG_2690|M.smegmatis_MC2_155 DPVGRRGAAGFVGFAIGGPLSDGLTAWIAAPLLFIGVLFGLLLITGTTIR TH_0579|M.thermoresistible__bu DPVARRHAAGFVGFAIGGPLADGLSVWIATPLLILGVLFGLLLITGTTIR Rv2748c|M.tuberculosis_H37Rv APESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIR Mb2769c|M.bovis_AF2122/97 APESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIR MMAR_1967|M.marinum_M SPELRQRAAGFIGFTIGGPLSDGLTVWIAAPLLFIGALFGLLLLTGTTIR MUL_3390|M.ulcerans_Agy99 SPELRQRAAGFIGFTIGGPLSDGLTVWIAAPLLFIGALFGLLLLTGTTIR MLBr_00977|M.leprae_Br4923 TPEVRRGAAGFLGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLTGTTVR MAV_3639|M.avium_104 DPDARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIR MAB_3074c|M.abscessus_ATCC_199 SPEGRSAAGGFVGFVIGGPLAQGLTAWIAAPLLVMAIVFGVLLLTGTTIR * * *.**:**.:****::*:: ***:***.:. :**:**::* *:* Mflv_3994|M.gilvum_PYR-GCK EVPATVRDMFTTRWR---DDDDEYYDDSYDGDESYDGDDYYDEDHDGDDD Mvan_2393|M.vanbaalenii_PYR-1 EVPAAVRDMFTTRWQREYDDEYDDYADEYDGDP--DADDDFSDGYYDDAD MSMEG_2690|M.smegmatis_MC2_155 EVPSTVRAMFSTRGF-----HDGEYDDEY------EYDEDYDDARYDERD TH_0579|M.thermoresistible__bu EVPSALRSLFTAHHD-----DGDDYDGDY-------AEDDYGDDHGADDD Rv2748c|M.tuberculosis_H37Rv EVPDAMRAMFGTRLL----------PREY--------ADDFEDFADFDGD Mb2769c|M.bovis_AF2122/97 EVPDAMRAMFGTRLL----------PREY--------ADDFEDFADFDGD MMAR_1967|M.marinum_M EVPDVLRGLFGTRLL----------QREYYDDE-FDDGDDYEGYSDFAGD MUL_3390|M.ulcerans_Agy99 EVPDVLRGLFGTRLL----------QREYYDDE-FDDGDDYEGYSDFAGD MLBr_00977|M.leprae_Br4923 EVPEVLRGMFDTGLF----------QRDY--------DDQYDAEYRYD-- MAV_3639|M.avium_104 ELPVVMRNLFHTRFV----------EDYT--------DEDYTDADYTDG- MAB_3074c|M.abscessus_ATCC_199 DVPDTLRNMFSPRDY-----------DEW--------DEEWDDPDYEDYE ::* .:* :* . : : Mflv_3994|M.gilvum_PYR-GCK R--DHDDRADDFSDGYYDEQIGDPDDEAQWPAAAQPTVPLTRPDG-PTGT Mvan_2393|M.vanbaalenii_PYR-1 P--GRDDAAWPTAN-QPTEPLEKPAAKAS-PAALPAALPATPPAALPAGS MSMEG_2690|M.smegmatis_MC2_155 -----GDFSDDFSDGYYDAEVPDEAAKTWPGSGPMAAIEAP---KAPAGT TH_0579|M.thermoresistible__bu R--DDDRGHADGSAGRRRSPQAAGADFSDGYYDDASAYGAEEPPAWPGGS Rv2748c|M.tuberculosis_H37Rv DADTVEVARQDFSDGYYDEVPLCSDDGPP--------------AWPS--- Mb2769c|M.bovis_AF2122/97 DADTVEVARQDFSDGYYDEVPLCSDDGPP--------------AWPS--- MMAR_1967|M.marinum_M DADTVEVAREDFSDGYYDEVPLRPDEELR--------------AWPSPNT MUL_3390|M.ulcerans_Agy99 DADTVEVAREDFSDGYYDEVPLRPDEELR--------------AWPSPNT MLBr_00977|M.leprae_Br4923 --DIPGAPPEDFSGCYDGSLVGGGDAEQK--------------VRGWPVT MAV_3639|M.avium_104 ---DYGDEPYDYAGEFDDATAQ-PEPEPA--------------AWAP--D MAB_3074c|M.abscessus_ATCC_199 D----GQSEGDYEATREFTRGATPMDNYP-------------------IE Mflv_3994|M.gilvum_PYR-GCK PMENYPLVDEDDDVAAPVAAP-AVTSRKKTPKEPK------------LSL Mvan_2393|M.vanbaalenii_PYR-1 PMDNYPIEDD----APTTPEP-AGRSRKKPRKEPA------------LSL MSMEG_2690|M.smegmatis_MC2_155 PMDNYPLEDA-----PTVPEP-AVKPRRKKPEAAKPANKAEEAAKETMVM TH_0579|M.thermoresistible__bu PMENYPLSDE----APTVPEPPARTSKRKSAKTAKTATARDP---QTGSL Rv2748c|M.tuberculosis_H37Rv ---AEVPQDD----TATIPEA---SAGRGSGRRGR--------RKDTQVL Mb2769c|M.bovis_AF2122/97 ---AEVPQDD----TATIPEA---SAGRGSGRRGR--------RKDTQVL MMAR_1967|M.marinum_M EPDGEIGEPD----APTVPEP---AVARGAGKAGKSGRSAPAEKQETLVL MUL_3390|M.ulcerans_Agy99 EPDGEIGEPD----APTVPEP---AVARGAGKAGKSGRSAPAEKQETLVL MLBr_00977|M.leprae_Br4923 DLAEVSLQDD----VPTTPEP---AVQAGTAEVHR-LTPRSAEEHRTQAL MAV_3639|M.avium_104 DDAQAALQDD----IPTVPEP---AVKTGRGRKRG----RAADNSDTIEL MAB_3074c|M.abscessus_ATCC_199 EEAAAAPEPP----APPAPKP---APVVKSTKKAK-------PKPQMPVV .. . . . : Mflv_3994|M.gilvum_PYR-GCK DRVVEGPYVLPPLDLLVAGEPPKRLTAANQQMTDAISSVLQQFKVDAAVT Mvan_2393|M.vanbaalenii_PYR-1 DRVVEGPYTLPPLDLLVAGDPPKRLTSANQQMTDAITSVLQQFKVDAAVT MSMEG_2690|M.smegmatis_MC2_155 DRVVEGPYVLPPLDLLIAGDPPKLRTAANDQMTDAITSVLEQFKVDAAVT TH_0579|M.thermoresistible__bu GRVVEGSYTLPSLGLLTAGDPPKKRSAANDRMVEAITQVLHEFKVDAAVT Rv2748c|M.tuberculosis_H37Rv DRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVT Mb2769c|M.bovis_AF2122/97 DRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVT MMAR_1967|M.marinum_M DRVVEGPYALPSMELLVAGDPPKKRSAANSHMAGAIGDVLTQFKVDAAVT MUL_3390|M.ulcerans_Agy99 DRVVEGPYALPSMELLVAGDPPKKRSAANSHMAGAIGDVLTQFKVDAAVT MLBr_00977|M.leprae_Br4923 DRAIEGSYTLPSMSLLLTGDPPKKCSAANNHMASAIGGVLTQFKVDAAVT MAV_3639|M.avium_104 DRVVEGPYVLPSLSLLVAGDPPKKRSAANNVMADAITEVLNQFKVDAAVT MAB_3074c|M.abscessus_ATCC_199 DRVIEGPYTLPSLDLLVAGDPPKESSAANDDMIAAITGVLEQFKVDAAVT .* :**.*.**.: ** :*:*** ::** * ** ** :******** Mflv_3994|M.gilvum_PYR-GCK GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS Mvan_2393|M.vanbaalenii_PYR-1 GCTRGPTVTRYEVELGPGVKVEKITALTRNIAYAVATESVRMLAPIPGKS MSMEG_2690|M.smegmatis_MC2_155 GCTRGPTVTRYEVELGPGVKVEKITALHRNIAYAVATESVRMLAPIPGKS TH_0579|M.thermoresistible__bu GCTRGPTVTRYEVELGPGVKVEKITALHRNIAYAVATESVRMLAPIPGKS Rv2748c|M.tuberculosis_H37Rv GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS Mb2769c|M.bovis_AF2122/97 GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS MMAR_1967|M.marinum_M GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS MUL_3390|M.ulcerans_Agy99 GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS MLBr_00977|M.leprae_Br4923 GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS MAV_3639|M.avium_104 GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS MAB_3074c|M.abscessus_ATCC_199 GFNRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATDSVRLLAPIPGKS * .************************ :********:***:******** Mflv_3994|M.gilvum_PYR-GCK AVGIEVPNIDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA Mvan_2393|M.vanbaalenii_PYR-1 AVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA MSMEG_2690|M.smegmatis_MC2_155 AVGIEVPNTDREMVRLSDVLTAPSTRRDHHPLVIGLGKDIEGDFVSANLA TH_0579|M.thermoresistible__bu AVGIEVPNTDREMVRLADVLTAPSTRRDDHPLVIGLGKDIEGEYISANLA Rv2748c|M.tuberculosis_H37Rv AVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLA Mb2769c|M.bovis_AF2122/97 AVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLA MMAR_1967|M.marinum_M AVGIEVPNTDREMVRLADVLTAPTTRRDHHPLVIGLGKDIEGDFISANLA MUL_3390|M.ulcerans_Agy99 AVGIEVPNTDREMVRLADVLTAPTTRRDHHPLVIGLGKDIEGDFISANLA MLBr_00977|M.leprae_Br4923 AVGIEVPNTDREAVRLADVLTAPSTRRDHHSLVIGLGKDIEGNFISANLA MAV_3639|M.avium_104 AVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA MAB_3074c|M.abscessus_ATCC_199 AVGIEVPNTDREMVRLADVLTAPETRRDHHPLVIGLGKDIEGDFISANLA ******** *** ***:***** ****.*.***********:::***** Mflv_3994|M.gilvum_PYR-GCK KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPDEVRMILIDPKMVELTPY Mvan_2393|M.vanbaalenii_PYR-1 KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY MSMEG_2690|M.smegmatis_MC2_155 KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY TH_0579|M.thermoresistible__bu KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPDEVRMILIDPKMVELTPY Rv2748c|M.tuberculosis_H37Rv KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY Mb2769c|M.bovis_AF2122/97 KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY MMAR_1967|M.marinum_M KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY MUL_3390|M.ulcerans_Agy99 KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY MLBr_00977|M.leprae_Br4923 KMPHLLVAGSTGSGKSSFVNSMLVSLLTRSTPEEVRMILIDPKMVELTPY MAV_3639|M.avium_104 KMPHLLVAGSTGSGKSSFVNSMLISLLARATPEEVRMILIDPKMVELTPY MAB_3074c|M.abscessus_ATCC_199 KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY ***********************:***:*:**:***************** Mflv_3994|M.gilvum_PYR-GCK EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNDKV Mvan_2393|M.vanbaalenii_PYR-1 EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNEKV MSMEG_2690|M.smegmatis_MC2_155 EGIPHLITPIITEPKKAAAALGWLVEEMEQRYQDMQASRVRHIDVFNEKV TH_0579|M.thermoresistible__bu EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNEKV Rv2748c|M.tuberculosis_H37Rv EGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKV Mb2769c|M.bovis_AF2122/97 EGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKV MMAR_1967|M.marinum_M EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNEKV MUL_3390|M.ulcerans_Agy99 EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNEKV MLBr_00977|M.leprae_Br4923 EGIPHLITPIITQPKKAAAALVWLVEEMEQRYQDMQASRVRHIDVFNEKV MAV_3639|M.avium_104 EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKV MAB_3074c|M.abscessus_ATCC_199 EGIPHLITPIITSPKKAASALAWLVEEMEQRYQDMQASRVRHINDFNAKV ************.*****:** ***:*****************: ** ** Mflv_3994|M.gilvum_PYR-GCK RSGEITAPLGSNRIYKPYPYILAIVDELADLMMTAPRDVEEAIVRITQKA Mvan_2393|M.vanbaalenii_PYR-1 RSGEITAPLGSNRVYKPYPYILAIVDELADLMMTAPRDVEEAIVRITQKA MSMEG_2690|M.smegmatis_MC2_155 RSGEISTPLGSERVYKPYPYIVAIVDELADLMMTAPRDVEDAIVRITQKA TH_0579|M.thermoresistible__bu RSGEITAPLGSKREYRPYPYILAIVDELADLMMTAPRDVEDAIVRITQKA Rv2748c|M.tuberculosis_H37Rv RSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA Mb2769c|M.bovis_AF2122/97 RSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA MMAR_1967|M.marinum_M RSGAITAPLGSQRVYKPYPYVVAIVDELADLMMTAPRDVEEAIVRITQKA MUL_3390|M.ulcerans_Agy99 RSGAITAPLGSQRVYKPYPYVVAIVDELADLMMTAPRDVEEAIVRITQKA MLBr_00977|M.leprae_Br4923 RSGEITAPLGSQRVYRPYPYILAIVDELADLMMTAPRDVEDAIVRITQKA MAV_3639|M.avium_104 RSGEITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA MAB_3074c|M.abscessus_ATCC_199 RSGEITTPLGSQREYRPYPYILAVVDELADLMMTAPRDVEDAIVRITQKA *** *::****:* *:****::*:****************:********* Mflv_3994|M.gilvum_PYR-GCK RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA Mvan_2393|M.vanbaalenii_PYR-1 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA MSMEG_2690|M.smegmatis_MC2_155 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA TH_0579|M.thermoresistible__bu RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA Rv2748c|M.tuberculosis_H37Rv RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA Mb2769c|M.bovis_AF2122/97 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA MMAR_1967|M.marinum_M RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA MUL_3390|M.ulcerans_Agy99 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA MLBr_00977|M.leprae_Br4923 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA MAV_3639|M.avium_104 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA MAB_3074c|M.abscessus_ATCC_199 RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA ***********************************************.** Mflv_3994|M.gilvum_PYR-GCK EKLIGMGDGLFLPMGANKPIRLQGAFITDEEIHAVVTATKDQAEPEFVEG Mvan_2393|M.vanbaalenii_PYR-1 EKLIGMGDGLFLPMGANKPIRLQGAFITDEEIHAVVSATKDQAEPEFVEG MSMEG_2690|M.smegmatis_MC2_155 EKLIGMGDGLFLPMGANKPIRMQGAFITDEEIHAVVAATKEQAEPEFVEG TH_0579|M.thermoresistible__bu EKLIGMGDGLFLPMGAGRPIRLQGAFVGDDEIHAVVNACKEQAEPEYTEG Rv2748c|M.tuberculosis_H37Rv EKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEG Mb2769c|M.bovis_AF2122/97 EKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEG MMAR_1967|M.marinum_M EKLIGMGDGLFLPMGAGKPIRLQGAFITDEEIHAVVTACKDQAEPEYTEG MUL_3390|M.ulcerans_Agy99 EKLIGMGDGLFLPMGAGKPIRLQGAFITDEEIHAVVTACKDQAEPEYTEG MLBr_00977|M.leprae_Br4923 EKLIGMGDGLFLPMGASKPVRLQGAFITDEEIHAVVTACKDQAEPEYTEG MAV_3639|M.avium_104 EKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQAEPEYTEG MAB_3074c|M.abscessus_ATCC_199 EKLIGMGDGLFLPMGAGRPIRMQGAFITDEEISAVVSACKEQAEPEYTEG ****************.:*:*:***:: *:** *** * *:*****:.** Mflv_3994|M.gilvum_PYR-GCK VTAVK-AGERK--DVDPDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV Mvan_2393|M.vanbaalenii_PYR-1 VTAVK-AGERK--DVDPDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV MSMEG_2690|M.smegmatis_MC2_155 VTAVK-AGERK--DVDPDIGDDLDVFLQAVELVVSSQFGSTSMLQRKLRV TH_0579|M.thermoresistible__bu VTAVK-TGERK--DVDPDIGDDMDLFLQAVELVVSSQFGSTSMLQRKLRV Rv2748c|M.tuberculosis_H37Rv VTTAKPTAERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV Mb2769c|M.bovis_AF2122/97 VTTAKPTAERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV MMAR_1967|M.marinum_M VTNAKPTGERT--DVDSDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV MUL_3390|M.ulcerans_Agy99 VTNAKPTGERT--DVDSDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV MLBr_00977|M.leprae_Br4923 VTTAKTTGERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV MAV_3639|M.avium_104 VTAVKTSSERA--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV MAB_3074c|M.abscessus_ATCC_199 VTTAKVGGGPGKDDVDPDIGDDMDAFLQAVELVVSSQFGSTSMLQRKLRV ** .* . ***.*****:* :************************ Mflv_3994|M.gilvum_PYR-GCK GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGGSDAN Mvan_2393|M.vanbaalenii_PYR-1 GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGGSDAN MSMEG_2690|M.smegmatis_MC2_155 GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPEDLAGTLALIRGGADAN TH_0579|M.thermoresistible__bu GFAKAGRLMDLMETRGIVGPSEGSKARQVLVKPEDLAATLASIRGGGEPD Rv2748c|M.tuberculosis_H37Rv GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGG-- Mb2769c|M.bovis_AF2122/97 GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGG-- MMAR_1967|M.marinum_M GFAKAGRLMDLMETRNIVGPSEGSKAREVLVKPDELAGTLALIRGGVA-- MUL_3390|M.ulcerans_Agy99 GFAKAGRLMDLMETRNIVGPSEGSKAREVLVKPDELAGTLALIRGGVA-- MLBr_00977|M.leprae_Br4923 GFAKAGRLMDLMETRSIVGPSEGSKAREVLVKADELAATLALIRGGAS-- MAV_3639|M.avium_104 GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGSGAGS MAB_3074c|M.abscessus_ATCC_199 GFAKAGRLMDLMETRGIVGPSEGSKAREVMVKPEDLAGVLASIRGGGGAD ***************.***********:*:**.::**..** ***. Mflv_3994|M.gilvum_PYR-GCK GADGED-DETDF Mvan_2393|M.vanbaalenii_PYR-1 GAEDPDGDEPDF MSMEG_2690|M.smegmatis_MC2_155 GAEPEDGEEF-- TH_0579|M.thermoresistible__bu DTDDTDDTAD-- Rv2748c|M.tuberculosis_H37Rv --E--------- Mb2769c|M.bovis_AF2122/97 --E--------- MMAR_1967|M.marinum_M --DDAPDED--- MUL_3390|M.ulcerans_Agy99 --DDAPDED--- MLBr_00977|M.leprae_Br4923 --ADGSNED--- MAV_3639|M.avium_104 ADADGGDPD--- MAB_3074c|M.abscessus_ATCC_199 EDEDDGGVPEDF