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M. tuberculosis H37Rv Rv2748c (ftsK)

annotation: POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK
coordinates: 3059855 - 3062506
length: 883

LGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRLAVMSSKTVARSGTRTSRSKAT
SRGASRSARSAVPRKRSRPVKGVGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRARDI
EPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAVVMLPLVAAAVAVVLMRTSPNPD
SRPRLILGASLIGLSFLGLCHLWAGSPEAPESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLL
LLAGITIREVPDAMRAMFGTRLLPREYADDFEDFADFDGDDADTVEVARQDFSDGYYDEVPLCSDDGPPA
WPSAEVPQDDTATIPEASAGRGSGRRGRRKDTQVLDRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGA
IGEVLTQFKVDAAVTGCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKSAVGIE
VPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLAKMPHLLVAGSTGSGKSSFVNSMLVS
LLTRATPEEVRMILIDPKMVELTPYEGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDD
FNDKVRSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKARAAGIHLVLATQRPS
VDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGAEKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAV
VTACKEQAEPEYTEGVTTAKPTAERTDVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRVGFAKAGR
LMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGGE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2748cftsK-100% (883)POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK
M. tuberculosis H37RvRv3447c-1e-1626.45% (310) hypothetical protein Rv3447c
M. tuberculosis H37RvRv3870-2e-1526.27% (236) transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2769cftsK0.0100.00% (883) cell division transmembrane protein FtsK
M. gilvum PYR-GCKMflv_3994-0.073.29% (861) cell divisionFtsK/SpoIIIE
M. leprae Br4923MLBr_00977ftsK0.077.40% (885) Cell division protein
M. abscessus ATCC 19977MAB_3074c-0.070.41% (838) cell division protein FtsK
M. marinum MMMAR_1967ftsK0.082.42% (859) cell division transmembrane protein FtsK
M. avium 104MAV_3639-0.082.03% (768) FtsK/SpoIIIE family protein
M. smegmatis MC2 155MSMEG_2690-0.072.52% (888) DNA translocase FtsK
M. thermoresistible (build 8)TH_0579ftsK0.075.82% (794) POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK
M. ulcerans Agy99MUL_3390ftsK0.082.04% (874) cell division transmembrane protein FtsK
M. vanbaalenii PYR-1Mvan_2393-0.073.50% (883) cell divisionFtsK/SpoIIIE

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3994|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2393|M.vanbaalenii_PYR-1       -------------------------------------MADGASEAFATRL
MSMEG_2690|M.smegmatis_MC2_155      --MLIQRSLDGCPAYRENPFPNRFVPLSCYRYQAVTCVADGDSGADATRL
TH_0579|M.thermoresistible__bu      --------------------------------------------------
Rv2748c|M.tuberculosis_H37Rv        MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRL
Mb2769c|M.bovis_AF2122/97           MLGPPGTPRVGRRDAARSLVTLLRRPWQRGEQIAVTSVADGVDGVIATRL
MMAR_1967|M.marinum_M               --------------------------------------------------
MUL_3390|M.ulcerans_Agy99           -------------------------------------MASGADDAIATSL
MLBr_00977|M.leprae_Br4923          ------MIRVIRSSFYPRMLTIDLDAWEETKKQSIASVACSADDIIAIRL
MAV_3639|M.avium_104                --------------------------------------------------
MAB_3074c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_3994|M.gilvum_PYR-GCK          --MASKTAARSSAR----QTRSKPAPRGGGRS-ARPAAPRRKPA------
Mvan_2393|M.vanbaalenii_PYR-1       TPMASKTAARSAAR----QTRSKAPSRGGARP-ARPAARR----------
MSMEG_2690|M.smegmatis_MC2_155      ADMANKTAARSRARSESSSSRSSGRSRGGAKQGAQDGARRKPPTRP----
TH_0579|M.thermoresistible__bu      --------------------------------------------------
Rv2748c|M.tuberculosis_H37Rv        AVMSSKTVARSGTRTSRSKATSRGASRSARSAVPRKRSRPVKG-------
Mb2769c|M.bovis_AF2122/97           AVMSSKTVARSGTRTSRSKATSRGASRSARSAVPRKRSRPVKG-------
MMAR_1967|M.marinum_M               --MASKTAARSGARTGRSKAASGGASRGGRATASAGPARPAKGTRKPAGK
MUL_3390|M.ulcerans_Agy99           AGMASKTAARSGARTSRSKAASGGASRGGRATASAGPARPAKGTRKPAGK
MLBr_00977|M.leprae_Br4923          VAMASKTVARSGNRTSSLKATSRGVSQSRRPVPP----RPRRN-------
MAV_3639|M.avium_104                --------------------------------------------------
MAB_3074c|M.abscessus_ATCC_199      --MASKTVSRSRSRNTKPGPRSRNTAPTRRPAPRRRNQRR----------
                                                                                      

Mflv_3994|M.gilvum_PYR-GCK          ----PRKPARR-NSSAISTAGTAVGKGVRAGWLMVAKGAGSTARSVGRAR
Mvan_2393|M.vanbaalenii_PYR-1       ------KPARR-HPSPVAAAGTAVGRGMRAGWLMLAKGAGSTARSVGRAR
MSMEG_2690|M.smegmatis_MC2_155      APQQRRKPARRPQASPVALAGHKLGQGARAGWLMLAKGAGSTARSVGRAR
TH_0579|M.thermoresistible__bu      ---------------------------------MVAKGVGSAARSVGRAR
Rv2748c|M.tuberculosis_H37Rv        ----VGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRAR
Mb2769c|M.bovis_AF2122/97           ----VGRPSRRHHRSLLVSTGLACGRAMRAVWMMAAKGTGGAARSIGRAR
MMAR_1967|M.marinum_M               PAKRVAKPIPRRNQSVLKVAGLAGGRAMRATWMMAAKGTGGAARSIGRAR
MUL_3390|M.ulcerans_Agy99           PAKRVAKPIPRRNQSVLKVAGLAGGRAMRATWMMAAKGTGGAARSIGRAR
MLBr_00977|M.leprae_Br4923          ------RPAERRNQSLLLAAGLTCGQAIRATWLVAAKGAGGAARSIGRAR
MAV_3639|M.avium_104                --------------------------------MLAARGTGGAARSIGRAR
MAB_3074c|M.abscessus_ATCC_199      -------------NQHWTAPLAALGRGARTGWHACAHGVGSLFRSVGRAH
                                                                       *:*.*.  **:***:

Mflv_3994|M.gilvum_PYR-GCK          ELEPGHRRDGIALALLGLAVIVAASSWFDAARPVGAWIDTTVRVLIGAAV
Mvan_2393|M.vanbaalenii_PYR-1       ELEPGHRRDGIALALLGLAVVVAASSWFDAARPVGAWIDTTVRIVIGSAV
MSMEG_2690|M.smegmatis_MC2_155      DIEPGHRRDGIALALLGIAVVVAASSWFDAARPVGEWIDTALRTLVGGPV
TH_0579|M.thermoresistible__bu      DIDPGHRRDGIALVLLAVAVVVAASSWFDAARPVGEWLDTVLRMVIGSAV
Rv2748c|M.tuberculosis_H37Rv        DIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAV
Mb2769c|M.bovis_AF2122/97           DIEPGHRRDGIALVLLGLAVVVAASSWFDAARPLGAWVDALLRTFIGSAV
MMAR_1967|M.marinum_M               DIEPGHRRDGVALVVLGIAVVVAASSWFDAARPVGAWVDAVLRTFIGSAV
MUL_3390|M.ulcerans_Agy99           DIEPGHRRDGVALVVLGIAVVVAASSWFDAARPVGAWVDAVLRTFIGSAV
MLBr_00977|M.leprae_Br4923          DIEPGHRRDGIALALLGLAVVVAASSWFDAARPIGAWVDAVLRTFIGSAV
MAV_3639|M.avium_104                DIDPGHRRDGIALLLLGFSVVVAASSWFHAAGPVGAWVDTALRTFIGAGV
MAB_3074c|M.abscessus_ATCC_199      DIEHGHRRDGVALALLGVAFVVGASSWFHAAKPVGGWIDNAFRVVVGSGV
                                    ::: ******:** :*..:.:*.*****.** *:* *:*  .* .:*. *

Mflv_3994|M.gilvum_PYR-GCK          VLVPVLLAVVGVTLMRSEPDPEARPRLILGSAMVALPAFGLWHLWAGAPA
Mvan_2393|M.vanbaalenii_PYR-1       VLVPIVLATIGVILMRSEPDPESRPRLILGFAMVALPALGLWHLWSGAPQ
MSMEG_2690|M.smegmatis_MC2_155      VLVPVLLAAIAVVLMRSEPDPEARPRLILGTAMIALPALGLWHLWAGSPT
TH_0579|M.thermoresistible__bu      VLVPIVVGGIAVVLMRSEPDPDTRPRLILGATMIALPVLGLWHLWSGAPD
Rv2748c|M.tuberculosis_H37Rv        VMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPE
Mb2769c|M.bovis_AF2122/97           VMLPLVAAAVAVVLMRTSPNPDSRPRLILGASLIGLSFLGLCHLWAGSPE
MMAR_1967|M.marinum_M               VLLPIVLAGTAIVLMRTEPNPDTRPRLILGSSLIALSFLGLRHLWAGSPE
MUL_3390|M.ulcerans_Agy99           VLLPIVLAGTAIVLMRTESNPDTRPRLILGSSLIALSFLGLRHLWAGSPE
MLBr_00977|M.leprae_Br4923          VVLPLVIAAVAVVLMRTQPNLDTRPRLILGATLIALSFLGLRHLWSGSPE
MAV_3639|M.avium_104                LALPVVTAAVAVTLMRTEPDPDVRPRLILGAGLIALSVLGLRHLWSGSPG
MAB_3074c|M.abscessus_ATCC_199      ALVPIIALVIAVFLMRTEPNPEERPRLLLGFAMVALPILGLWHLFAGSPD
                                      :*::    .: ***:..: : ****:**  ::.*. :** **::*:* 

Mflv_3994|M.gilvum_PYR-GCK          DPVERRHAGGFLGFALGGPLSDGLTAWIAAPLLFIGVLFGVLLLTGTTIR
Mvan_2393|M.vanbaalenii_PYR-1       DPTARQHAAGFVGFVVGGPLSDGVTPWIAAPLLFIGVLFGLLLVTGTTIR
MSMEG_2690|M.smegmatis_MC2_155      DPVGRRGAAGFVGFAIGGPLSDGLTAWIAAPLLFIGVLFGLLLITGTTIR
TH_0579|M.thermoresistible__bu      DPVARRHAAGFVGFAIGGPLADGLSVWIATPLLILGVLFGLLLITGTTIR
Rv2748c|M.tuberculosis_H37Rv        APESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIR
Mb2769c|M.bovis_AF2122/97           APESRLRAAGFIGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLAGITIR
MMAR_1967|M.marinum_M               SPELRQRAAGFIGFTIGGPLSDGLTVWIAAPLLFIGALFGLLLLTGTTIR
MUL_3390|M.ulcerans_Agy99           SPELRQRAAGFIGFTIGGPLSDGLTVWIAAPLLFIGALFGLLLLTGTTIR
MLBr_00977|M.leprae_Br4923          TPEVRRGAAGFLGFAIGGPLSDGLTAWIAAPLLFIGALFGLLLLTGTTVR
MAV_3639|M.avium_104                DPDARRRAAGFIGFAIGGPLSDGLTPWIAAPLLFIGFMFGLLLLTGTTIR
MAB_3074c|M.abscessus_ATCC_199      SPEGRSAAGGFVGFVIGGPLAQGLTAWIAAPLLVMAIVFGVLLLTGTTIR
                                     *  *  *.**:**.:****::*:: ***:***.:. :**:**::* *:*

Mflv_3994|M.gilvum_PYR-GCK          EVPATVRDMFTTRWR---DDDDEYYDDSYDGDESYDGDDYYDEDHDGDDD
Mvan_2393|M.vanbaalenii_PYR-1       EVPAAVRDMFTTRWQREYDDEYDDYADEYDGDP--DADDDFSDGYYDDAD
MSMEG_2690|M.smegmatis_MC2_155      EVPSTVRAMFSTRGF-----HDGEYDDEY------EYDEDYDDARYDERD
TH_0579|M.thermoresistible__bu      EVPSALRSLFTAHHD-----DGDDYDGDY-------AEDDYGDDHGADDD
Rv2748c|M.tuberculosis_H37Rv        EVPDAMRAMFGTRLL----------PREY--------ADDFEDFADFDGD
Mb2769c|M.bovis_AF2122/97           EVPDAMRAMFGTRLL----------PREY--------ADDFEDFADFDGD
MMAR_1967|M.marinum_M               EVPDVLRGLFGTRLL----------QREYYDDE-FDDGDDYEGYSDFAGD
MUL_3390|M.ulcerans_Agy99           EVPDVLRGLFGTRLL----------QREYYDDE-FDDGDDYEGYSDFAGD
MLBr_00977|M.leprae_Br4923          EVPEVLRGMFDTGLF----------QRDY--------DDQYDAEYRYD--
MAV_3639|M.avium_104                ELPVVMRNLFHTRFV----------EDYT--------DEDYTDADYTDG-
MAB_3074c|M.abscessus_ATCC_199      DVPDTLRNMFSPRDY-----------DEW--------DEEWDDPDYEDYE
                                    ::* .:* :* .                          : :         

Mflv_3994|M.gilvum_PYR-GCK          R--DHDDRADDFSDGYYDEQIGDPDDEAQWPAAAQPTVPLTRPDG-PTGT
Mvan_2393|M.vanbaalenii_PYR-1       P--GRDDAAWPTAN-QPTEPLEKPAAKAS-PAALPAALPATPPAALPAGS
MSMEG_2690|M.smegmatis_MC2_155      -----GDFSDDFSDGYYDAEVPDEAAKTWPGSGPMAAIEAP---KAPAGT
TH_0579|M.thermoresistible__bu      R--DDDRGHADGSAGRRRSPQAAGADFSDGYYDDASAYGAEEPPAWPGGS
Rv2748c|M.tuberculosis_H37Rv        DADTVEVARQDFSDGYYDEVPLCSDDGPP--------------AWPS---
Mb2769c|M.bovis_AF2122/97           DADTVEVARQDFSDGYYDEVPLCSDDGPP--------------AWPS---
MMAR_1967|M.marinum_M               DADTVEVAREDFSDGYYDEVPLRPDEELR--------------AWPSPNT
MUL_3390|M.ulcerans_Agy99           DADTVEVAREDFSDGYYDEVPLRPDEELR--------------AWPSPNT
MLBr_00977|M.leprae_Br4923          --DIPGAPPEDFSGCYDGSLVGGGDAEQK--------------VRGWPVT
MAV_3639|M.avium_104                ---DYGDEPYDYAGEFDDATAQ-PEPEPA--------------AWAP--D
MAB_3074c|M.abscessus_ATCC_199      D----GQSEGDYEATREFTRGATPMDNYP-------------------IE
                                                                                      

Mflv_3994|M.gilvum_PYR-GCK          PMENYPLVDEDDDVAAPVAAP-AVTSRKKTPKEPK------------LSL
Mvan_2393|M.vanbaalenii_PYR-1       PMDNYPIEDD----APTTPEP-AGRSRKKPRKEPA------------LSL
MSMEG_2690|M.smegmatis_MC2_155      PMDNYPLEDA-----PTVPEP-AVKPRRKKPEAAKPANKAEEAAKETMVM
TH_0579|M.thermoresistible__bu      PMENYPLSDE----APTVPEPPARTSKRKSAKTAKTATARDP---QTGSL
Rv2748c|M.tuberculosis_H37Rv        ---AEVPQDD----TATIPEA---SAGRGSGRRGR--------RKDTQVL
Mb2769c|M.bovis_AF2122/97           ---AEVPQDD----TATIPEA---SAGRGSGRRGR--------RKDTQVL
MMAR_1967|M.marinum_M               EPDGEIGEPD----APTVPEP---AVARGAGKAGKSGRSAPAEKQETLVL
MUL_3390|M.ulcerans_Agy99           EPDGEIGEPD----APTVPEP---AVARGAGKAGKSGRSAPAEKQETLVL
MLBr_00977|M.leprae_Br4923          DLAEVSLQDD----VPTTPEP---AVQAGTAEVHR-LTPRSAEEHRTQAL
MAV_3639|M.avium_104                DDAQAALQDD----IPTVPEP---AVKTGRGRKRG----RAADNSDTIEL
MAB_3074c|M.abscessus_ATCC_199      EEAAAAPEPP----APPAPKP---APVVKSTKKAK-------PKPQMPVV
                                                   .. . .          .                 :

Mflv_3994|M.gilvum_PYR-GCK          DRVVEGPYVLPPLDLLVAGEPPKRLTAANQQMTDAISSVLQQFKVDAAVT
Mvan_2393|M.vanbaalenii_PYR-1       DRVVEGPYTLPPLDLLVAGDPPKRLTSANQQMTDAITSVLQQFKVDAAVT
MSMEG_2690|M.smegmatis_MC2_155      DRVVEGPYVLPPLDLLIAGDPPKLRTAANDQMTDAITSVLEQFKVDAAVT
TH_0579|M.thermoresistible__bu      GRVVEGSYTLPSLGLLTAGDPPKKRSAANDRMVEAITQVLHEFKVDAAVT
Rv2748c|M.tuberculosis_H37Rv        DRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVT
Mb2769c|M.bovis_AF2122/97           DRIVEGPYTLPSLDLLISGDPPKKRSAANTHMAGAIGEVLTQFKVDAAVT
MMAR_1967|M.marinum_M               DRVVEGPYALPSMELLVAGDPPKKRSAANSHMAGAIGDVLTQFKVDAAVT
MUL_3390|M.ulcerans_Agy99           DRVVEGPYALPSMELLVAGDPPKKRSAANSHMAGAIGDVLTQFKVDAAVT
MLBr_00977|M.leprae_Br4923          DRAIEGSYTLPSMSLLLTGDPPKKCSAANNHMASAIGGVLTQFKVDAAVT
MAV_3639|M.avium_104                DRVVEGPYVLPSLSLLVAGDPPKKRSAANNVMADAITEVLNQFKVDAAVT
MAB_3074c|M.abscessus_ATCC_199      DRVIEGPYTLPSLDLLVAGDPPKESSAANDDMIAAITGVLEQFKVDAAVT
                                    .* :**.*.**.: ** :*:***  ::**  *  **  ** :********

Mflv_3994|M.gilvum_PYR-GCK          GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS
Mvan_2393|M.vanbaalenii_PYR-1       GCTRGPTVTRYEVELGPGVKVEKITALTRNIAYAVATESVRMLAPIPGKS
MSMEG_2690|M.smegmatis_MC2_155      GCTRGPTVTRYEVELGPGVKVEKITALHRNIAYAVATESVRMLAPIPGKS
TH_0579|M.thermoresistible__bu      GCTRGPTVTRYEVELGPGVKVEKITALHRNIAYAVATESVRMLAPIPGKS
Rv2748c|M.tuberculosis_H37Rv        GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS
Mb2769c|M.bovis_AF2122/97           GCTRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATESVRMLAPIPGKS
MMAR_1967|M.marinum_M               GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS
MUL_3390|M.ulcerans_Agy99           GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS
MLBr_00977|M.leprae_Br4923          GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS
MAV_3639|M.avium_104                GCTRGPTVTRYEVELGPGVKVEKITALQKNIAYAVATESVRMLAPIPGKS
MAB_3074c|M.abscessus_ATCC_199      GFNRGPTVTRYEVELGPGVKVEKITALQRNIAYAVATDSVRLLAPIPGKS
                                    * .************************ :********:***:********

Mflv_3994|M.gilvum_PYR-GCK          AVGIEVPNIDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA
Mvan_2393|M.vanbaalenii_PYR-1       AVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA
MSMEG_2690|M.smegmatis_MC2_155      AVGIEVPNTDREMVRLSDVLTAPSTRRDHHPLVIGLGKDIEGDFVSANLA
TH_0579|M.thermoresistible__bu      AVGIEVPNTDREMVRLADVLTAPSTRRDDHPLVIGLGKDIEGEYISANLA
Rv2748c|M.tuberculosis_H37Rv        AVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLA
Mb2769c|M.bovis_AF2122/97           AVGIEVPNTDREMVRLADVLTARETRRDHHPLVIGLGKDIEGDFISANLA
MMAR_1967|M.marinum_M               AVGIEVPNTDREMVRLADVLTAPTTRRDHHPLVIGLGKDIEGDFISANLA
MUL_3390|M.ulcerans_Agy99           AVGIEVPNTDREMVRLADVLTAPTTRRDHHPLVIGLGKDIEGDFISANLA
MLBr_00977|M.leprae_Br4923          AVGIEVPNTDREAVRLADVLTAPSTRRDHHSLVIGLGKDIEGNFISANLA
MAV_3639|M.avium_104                AVGIEVPNTDREMVRLADVLTAPSTRRDHHPLVIGLGKDIEGDFISANLA
MAB_3074c|M.abscessus_ATCC_199      AVGIEVPNTDREMVRLADVLTAPETRRDHHPLVIGLGKDIEGDFISANLA
                                    ******** *** ***:*****  ****.*.***********:::*****

Mflv_3994|M.gilvum_PYR-GCK          KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPDEVRMILIDPKMVELTPY
Mvan_2393|M.vanbaalenii_PYR-1       KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY
MSMEG_2690|M.smegmatis_MC2_155      KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY
TH_0579|M.thermoresistible__bu      KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPDEVRMILIDPKMVELTPY
Rv2748c|M.tuberculosis_H37Rv        KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY
Mb2769c|M.bovis_AF2122/97           KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY
MMAR_1967|M.marinum_M               KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY
MUL_3390|M.ulcerans_Agy99           KMPHLLVAGSTGSGKSSFVNSMLVSLLTRATPEEVRMILIDPKMVELTPY
MLBr_00977|M.leprae_Br4923          KMPHLLVAGSTGSGKSSFVNSMLVSLLTRSTPEEVRMILIDPKMVELTPY
MAV_3639|M.avium_104                KMPHLLVAGSTGSGKSSFVNSMLISLLARATPEEVRMILIDPKMVELTPY
MAB_3074c|M.abscessus_ATCC_199      KMPHLLVAGSTGSGKSSFVNSMLVSLLARATPEEVRMILIDPKMVELTPY
                                    ***********************:***:*:**:*****************

Mflv_3994|M.gilvum_PYR-GCK          EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNDKV
Mvan_2393|M.vanbaalenii_PYR-1       EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNEKV
MSMEG_2690|M.smegmatis_MC2_155      EGIPHLITPIITEPKKAAAALGWLVEEMEQRYQDMQASRVRHIDVFNEKV
TH_0579|M.thermoresistible__bu      EGIPHLITPIITEPKKAAAALAWLVEEMEQRYQDMQASRVRHIDVFNEKV
Rv2748c|M.tuberculosis_H37Rv        EGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKV
Mb2769c|M.bovis_AF2122/97           EGIPHLITPIITQPKKAAAALAWLVDEMEQRYQDMQASRVRHIDDFNDKV
MMAR_1967|M.marinum_M               EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNEKV
MUL_3390|M.ulcerans_Agy99           EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNEKV
MLBr_00977|M.leprae_Br4923          EGIPHLITPIITQPKKAAAALVWLVEEMEQRYQDMQASRVRHIDVFNEKV
MAV_3639|M.avium_104                EGIPHLITPIITQPKKAAAALAWLVEEMEQRYQDMQASRVRHIDDFNAKV
MAB_3074c|M.abscessus_ATCC_199      EGIPHLITPIITSPKKAASALAWLVEEMEQRYQDMQASRVRHINDFNAKV
                                    ************.*****:** ***:*****************: ** **

Mflv_3994|M.gilvum_PYR-GCK          RSGEITAPLGSNRIYKPYPYILAIVDELADLMMTAPRDVEEAIVRITQKA
Mvan_2393|M.vanbaalenii_PYR-1       RSGEITAPLGSNRVYKPYPYILAIVDELADLMMTAPRDVEEAIVRITQKA
MSMEG_2690|M.smegmatis_MC2_155      RSGEISTPLGSERVYKPYPYIVAIVDELADLMMTAPRDVEDAIVRITQKA
TH_0579|M.thermoresistible__bu      RSGEITAPLGSKREYRPYPYILAIVDELADLMMTAPRDVEDAIVRITQKA
Rv2748c|M.tuberculosis_H37Rv        RSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA
Mb2769c|M.bovis_AF2122/97           RSGAITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA
MMAR_1967|M.marinum_M               RSGAITAPLGSQRVYKPYPYVVAIVDELADLMMTAPRDVEEAIVRITQKA
MUL_3390|M.ulcerans_Agy99           RSGAITAPLGSQRVYKPYPYVVAIVDELADLMMTAPRDVEEAIVRITQKA
MLBr_00977|M.leprae_Br4923          RSGEITAPLGSQRVYRPYPYILAIVDELADLMMTAPRDVEDAIVRITQKA
MAV_3639|M.avium_104                RSGEITAPLGSQREYRPYPYVVAIVDELADLMMTAPRDVEDAIVRITQKA
MAB_3074c|M.abscessus_ATCC_199      RSGEITTPLGSQREYRPYPYILAVVDELADLMMTAPRDVEDAIVRITQKA
                                    *** *::****:* *:****::*:****************:*********

Mflv_3994|M.gilvum_PYR-GCK          RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA
Mvan_2393|M.vanbaalenii_PYR-1       RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA
MSMEG_2690|M.smegmatis_MC2_155      RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
TH_0579|M.thermoresistible__bu      RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
Rv2748c|M.tuberculosis_H37Rv        RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
Mb2769c|M.bovis_AF2122/97           RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
MMAR_1967|M.marinum_M               RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
MUL_3390|M.ulcerans_Agy99           RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
MLBr_00977|M.leprae_Br4923          RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
MAV_3639|M.avium_104                RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQAGA
MAB_3074c|M.abscessus_ATCC_199      RAAGIHLVLATQRPSVDVVTGLIKTNVPSRLAFATSSLTDSRVILDQPGA
                                    ***********************************************.**

Mflv_3994|M.gilvum_PYR-GCK          EKLIGMGDGLFLPMGANKPIRLQGAFITDEEIHAVVTATKDQAEPEFVEG
Mvan_2393|M.vanbaalenii_PYR-1       EKLIGMGDGLFLPMGANKPIRLQGAFITDEEIHAVVSATKDQAEPEFVEG
MSMEG_2690|M.smegmatis_MC2_155      EKLIGMGDGLFLPMGANKPIRMQGAFITDEEIHAVVAATKEQAEPEFVEG
TH_0579|M.thermoresistible__bu      EKLIGMGDGLFLPMGAGRPIRLQGAFVGDDEIHAVVNACKEQAEPEYTEG
Rv2748c|M.tuberculosis_H37Rv        EKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEG
Mb2769c|M.bovis_AF2122/97           EKLIGMGDGLFLPMGASKPLRLQGAYVSDEEIHAVVTACKEQAEPEYTEG
MMAR_1967|M.marinum_M               EKLIGMGDGLFLPMGAGKPIRLQGAFITDEEIHAVVTACKDQAEPEYTEG
MUL_3390|M.ulcerans_Agy99           EKLIGMGDGLFLPMGAGKPIRLQGAFITDEEIHAVVTACKDQAEPEYTEG
MLBr_00977|M.leprae_Br4923          EKLIGMGDGLFLPMGASKPVRLQGAFITDEEIHAVVTACKDQAEPEYTEG
MAV_3639|M.avium_104                EKLIGMGDGLFLPMGASKPIRLQGAFITDEEIQAVVAACKDQAEPEYTEG
MAB_3074c|M.abscessus_ATCC_199      EKLIGMGDGLFLPMGAGRPIRMQGAFITDEEISAVVSACKEQAEPEYTEG
                                    ****************.:*:*:***:: *:** *** * *:*****:.**

Mflv_3994|M.gilvum_PYR-GCK          VTAVK-AGERK--DVDPDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV
Mvan_2393|M.vanbaalenii_PYR-1       VTAVK-AGERK--DVDPDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV
MSMEG_2690|M.smegmatis_MC2_155      VTAVK-AGERK--DVDPDIGDDLDVFLQAVELVVSSQFGSTSMLQRKLRV
TH_0579|M.thermoresistible__bu      VTAVK-TGERK--DVDPDIGDDMDLFLQAVELVVSSQFGSTSMLQRKLRV
Rv2748c|M.tuberculosis_H37Rv        VTTAKPTAERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV
Mb2769c|M.bovis_AF2122/97           VTTAKPTAERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV
MMAR_1967|M.marinum_M               VTNAKPTGERT--DVDSDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV
MUL_3390|M.ulcerans_Agy99           VTNAKPTGERT--DVDSDIGDDMDVLLQAVELVVSSQFGSTSMLQRKLRV
MLBr_00977|M.leprae_Br4923          VTTAKTTGERT--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV
MAV_3639|M.avium_104                VTAVKTSSERA--DVDPDIGDDMDVFLQAVELVVSSQFGSTSMLQRKLRV
MAB_3074c|M.abscessus_ATCC_199      VTTAKVGGGPGKDDVDPDIGDDMDAFLQAVELVVSSQFGSTSMLQRKLRV
                                    ** .*  .     ***.*****:* :************************

Mflv_3994|M.gilvum_PYR-GCK          GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGGSDAN
Mvan_2393|M.vanbaalenii_PYR-1       GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGGSDAN
MSMEG_2690|M.smegmatis_MC2_155      GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPEDLAGTLALIRGGADAN
TH_0579|M.thermoresistible__bu      GFAKAGRLMDLMETRGIVGPSEGSKARQVLVKPEDLAATLASIRGGGEPD
Rv2748c|M.tuberculosis_H37Rv        GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGG--
Mb2769c|M.bovis_AF2122/97           GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLAAIRGDGG--
MMAR_1967|M.marinum_M               GFAKAGRLMDLMETRNIVGPSEGSKAREVLVKPDELAGTLALIRGGVA--
MUL_3390|M.ulcerans_Agy99           GFAKAGRLMDLMETRNIVGPSEGSKAREVLVKPDELAGTLALIRGGVA--
MLBr_00977|M.leprae_Br4923          GFAKAGRLMDLMETRSIVGPSEGSKAREVLVKADELAATLALIRGGAS--
MAV_3639|M.avium_104                GFAKAGRLMDLMETRGIVGPSEGSKAREVLVKPDELAGTLALIRGSGAGS
MAB_3074c|M.abscessus_ATCC_199      GFAKAGRLMDLMETRGIVGPSEGSKAREVMVKPEDLAGVLASIRGGGGAD
                                    ***************.***********:*:**.::**..** ***.    

Mflv_3994|M.gilvum_PYR-GCK          GADGED-DETDF
Mvan_2393|M.vanbaalenii_PYR-1       GAEDPDGDEPDF
MSMEG_2690|M.smegmatis_MC2_155      GAEPEDGEEF--
TH_0579|M.thermoresistible__bu      DTDDTDDTAD--
Rv2748c|M.tuberculosis_H37Rv        --E---------
Mb2769c|M.bovis_AF2122/97           --E---------
MMAR_1967|M.marinum_M               --DDAPDED---
MUL_3390|M.ulcerans_Agy99           --DDAPDED---
MLBr_00977|M.leprae_Br4923          --ADGSNED---
MAV_3639|M.avium_104                ADADGGDPD---
MAB_3074c|M.abscessus_ATCC_199      EDEDDGGVPEDF