For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MDVEALLQSIPPLMVYLVVGAVVGIESLGIPLPGEIVLVSAAVLSSHPELAVNPIGVGGAAVIGAVVGDS IGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFLGRFIALLRIFAGPLAGALKMPYP RFLAANVTGGICWAGGTTALVYFAGMAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHC RKAGTTAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2637 | dedA | - | 100% (218) | POSSIBLE TRANSMEMBRANE PROTEIN DEDA |
| M. tuberculosis H37Rv | Rv0364 | - | 7e-18 | 32.94% (170) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2670 | dedA | 1e-122 | 100.00% (218) | transmembrane protein DedA |
| M. gilvum PYR-GCK | Mflv_0237 | - | 3e-10 | 34.95% (103) | hypothetical protein Mflv_0237 |
| M. leprae Br4923 | MLBr_00467 | dedA | 5e-98 | 82.78% (209) | hypothetical protein MLBr_00467 |
| M. abscessus ATCC 19977 | MAB_4661 | - | 8e-19 | 33.12% (160) | hypothetical protein MAB_4661 |
| M. marinum M | MMAR_2063 | dedA | 1e-104 | 83.49% (218) | transmembrane protein DedA |
| M. avium 104 | MAV_3516 | - | 1e-97 | 85.00% (200) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_0750 | - | 6e-13 | 33.57% (140) | membrane protein |
| M. thermoresistible (build 8) | TH_1640 | - | 1e-16 | 30.94% (181) | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3280 | dedA | 1e-104 | 83.03% (218) | transmembrane protein DedA |
| M. vanbaalenii PYR-1 | Mvan_0668 | - | 1e-11 | 31.03% (174) | hypothetical protein Mvan_0668 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2637|M.tuberculosis_H37Rv -------------------MDVEALLQSIPPLMVYLVVG--AVVGIES--
Mb2670|M.bovis_AF2122/97 -------------------MDVEALLQSIPPLMVYLVVG--AVVGIES--
MAV_3516|M.avium_104 ------------------------------------MVG--GVVGIES--
MMAR_2063|M.marinum_M -------------------MDVEALLHTIPPLAVYILVG--AVVGVES--
MUL_3280|M.ulcerans_Agy99 -------------------MDVEALLHTIPPLAVYILVG--AVVGVES--
MLBr_00467|M.leprae_Br4923 -------------------MDVDALLQSIPPLAVYLLVS--GVVGVES--
Mflv_0237|M.gilvum_PYR-GCK -------MVVDNLALMPDFLDPINLLS---YFGTWALIGLLVVVFVESGV
Mvan_0668|M.vanbaalenii_PYR-1 -------MVVDNLALMPDFLDPINLLS---YFGTWALIGLLVVVFVESGV
MSMEG_0750|M.smegmatis_MC2_155 MIDTALPEVTTNLALMPDFMDPLNLIG---YFGTWALVGILLVVFIESGV
MAB_4661|M.abscessus_ATCC_1997 ---------MDMGLAPADVMDPMYWLGEGGLFGGAVLAGVMVIVFIETGL
TH_1640|M.thermoresistible__bu --------MSTTVMAMPGILDPMFWIGPDGLFAAAVLPAILIIVFIETGL
: . :* :*:
Rv2637|M.tuberculosis_H37Rv LGIPLPGEIVLVSAAVLSSHPELA----------VNPIGVGGAAVIGAVV
Mb2670|M.bovis_AF2122/97 LGIPLPGEIVLVSAAVLSSHPELA----------VNPIGVGGAAVIGAVV
MAV_3516|M.avium_104 LGIPLPGEIVLVTAALMSSHHDLA----------VNPLGVGVAAVIGAVI
MMAR_2063|M.marinum_M LGIPLPGEIVLVSAALLSSHHELA----------VNPVGVGAAAVIGAVI
MUL_3280|M.ulcerans_Agy99 LGIPLPGEIVLVSAALLSSHHELA----------VNPVGVGAAAVIGAVI
MLBr_00467|M.leprae_Br4923 LGIPLPGEVVLVSAALLSSRHDLA----------VSSIGVGVVAVIGAAV
Mflv_0237|M.gilvum_PYR-GCK LFPILPGDSLLFVAGMLAAGISAQSAEGNVAVVNFQLWQLLVFIPIAAVL
Mvan_0668|M.vanbaalenii_PYR-1 LFPVLPGDSLLFVAGMLAAGTAAASKEGNVANADFQLWQLLVFIPIAAVL
MSMEG_0750|M.smegmatis_MC2_155 LFPVLPGDSLLFVAGMLAAGTAAK---GTAVDANFQLWQLLVFIPIAAIL
MAB_4661|M.abscessus_ATCC_1997 LFPFLPGDTLLFSAGLIAAQPNSP----------VAIQVLAPCAALAALL
TH_1640|M.thermoresistible__bu LFPLLPGDSLLFTGGLLAAG--GT----------MNIWLLCITVTIVAIL
* ***: :*. ..:::: . : : * :
Rv2637|M.tuberculosis_H37Rv GDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFL
Mb2670|M.bovis_AF2122/97 GDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFL
MAV_3516|M.avium_104 GDSIGYAVGRRFGMPLFERLGRRFPKHFGPGHVALAEKLFNRWGARAVFL
MMAR_2063|M.marinum_M GDSIGYTIGRRFGMPLFDRLGRRFPKHFGPGHVALAERLFSRWGSRAVFF
MUL_3280|M.ulcerans_Agy99 GDSIGYTIGRRFGMPLFDRLGRRFPKHFGPGHVALAERLFSRWGSQAVFF
MLBr_00467|M.leprae_Br4923 GDSIGYAIGRRFGMPLFDHLGRRFPKHFGPGHVALVERLFNRWGVRAVFF
Mflv_0237|M.gilvum_PYR-GCK GAQVGYWIGRNVGTAMFTP-NARFLKQK---YLDEAHLFFEQRGPFAIVI
Mvan_0668|M.vanbaalenii_PYR-1 GAQVGYWIGRNVGTAMFKP-DARFLKQK---YLDEAHLFFEQRGPFAIVV
MSMEG_0750|M.smegmatis_MC2_155 GGQVGYIIGRTIGTSMFKP-EARILKQK---YLDEAHEFFEQRGPFAIVI
MAB_4661|M.abscessus_ATCC_1997 GSQCGYFIGRRLGPALFKKEDARFFKQR---YLTVSREFFDKHGPKTLLI
TH_1640|M.thermoresistible__bu GDQCAYYIGRRIGPALFNKEDSRFFKKS---YVEQSHEFFEKYGPYTIIL
* . .* :** .* .:* *: *: :: . :*.: * ::..
Rv2637|M.tuberculosis_H37Rv GRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAG--
Mb2670|M.bovis_AF2122/97 GRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAG--
MAV_3516|M.avium_104 GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYFAG--
MMAR_2063|M.marinum_M GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYYAG--
MUL_3280|M.ulcerans_Agy99 GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYYAG--
MLBr_00467|M.leprae_Br4923 GRFIALLRILAGPLAGALKMHYPRFLAANVSGAICWAGGTTALVYFAG--
Mflv_0237|M.gilvum_PYR-GCK ARFVPIVRTLAPITAGAAKMNYAVFTLYNAVGAIVWGVGLTLLGFFLGRI
Mvan_0668|M.vanbaalenii_PYR-1 ARFVPIVRTLAPITAGAAKMNYAVFTVYNAVGAVVWGAGLTLLGYWLGRF
MSMEG_0750|M.smegmatis_MC2_155 ARFVPIVRTLAPITAGAAKMRYPVFTAFNVLGAIVWGVGLTLLGYWLGQF
MAB_4661|M.abscessus_ATCC_1997 AQFIGVVRTFTPVIAGMSGMRYPTFLLYNAIGSAAWGTGLTVVGYFLGNI
TH_1640|M.thermoresistible__bu ARFVPIVRTYAPVLAGVSYMRYSVFLTFNAVGGIAWGTGVTLLGYFLGNI
.:*: ::* : ** * *. * *. *. *. * * : :: *
Rv2637|M.tuberculosis_H37Rv MAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGT
Mb2670|M.bovis_AF2122/97 MAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGT
MAV_3516|M.avium_104 VAAERWLERFSWIGLVVAVVAGLTAAILLRERTSRAIAELEAEHYRKTGN
MMAR_2063|M.marinum_M MAAEHWLQRFSWVGLVIAVVGGLIAAILLRERTARAIAELEEEHHRKAQT
MUL_3280|M.ulcerans_Agy99 MAAEHWLQRFSWVGLVIAVVGGLIAAILLRERTARAIAELEEEHHRKAQT
MLBr_00467|M.leprae_Br4923 MAAERWMERFSWIALIITVVVGIIAAILLRERTSRIIAELEMEYKNRRH-
Mflv_0237|M.gilvum_PYR-GCK EIIQKLLEPIVIGIVILSVLPIAIEWYKRRKAAKQAGI--ATPPMEAGEQ
Mvan_0668|M.vanbaalenii_PYR-1 EVIQKLLEPIVIGIVLLSVLPMLIEWYRRRKAAKQAGG--ATEAEPTG--
MSMEG_0750|M.smegmatis_MC2_155 EIIQKLLEPIFILIVVASVAPMFIEWYKRRRAAKRASS--TDTATDAASP
MAB_4661|M.abscessus_ATCC_1997 AFVGEHLDIIILVIAILSTLPAAATAAKVYLEKRRAVT-----------E
TH_1640|M.thermoresistible__bu TFVKENLEYMILLIVFLSVLPMIFSVTKGMLERRRARSGPALAAEPLPKQ
. :: : . :. :
Rv2637|M.tuberculosis_H37Rv TAA---
Mb2670|M.bovis_AF2122/97 TAA---
MAV_3516|M.avium_104 TATDPV
MMAR_2063|M.marinum_M AEA---
MUL_3280|M.ulcerans_Agy99 AEA---
MLBr_00467|M.leprae_Br4923 ------
Mflv_0237|M.gilvum_PYR-GCK AG----
Mvan_0668|M.vanbaalenii_PYR-1 ------
MSMEG_0750|M.smegmatis_MC2_155 AS----
MAB_4661|M.abscessus_ATCC_1997 NG----
TH_1640|M.thermoresistible__bu SG----