For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb2670 (dedA)

annotation: transmembrane protein DedA
coordinates: 2931048 - 2931704
length: 218

MDVEALLQSIPPLMVYLVVGAVVGIESLGIPLPGEIVLVSAAVLSSHPELAVNPIGVGGAAVIGAVVGDS
IGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFLGRFIALLRIFAGPLAGALKMPYP
RFLAANVTGGICWAGGTTALVYFAGMAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHC
RKAGTTAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2670dedA-100% (218)transmembrane protein DedA
M. bovis AF2122 / 97Mb0371-1e-1735.07% (134) transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_0237-3e-1034.95% (103) hypothetical protein Mflv_0237
M. tuberculosis H37RvRv2637dedA1e-122100.00% (218) transmembrane protein DedA
M. leprae Br4923MLBr_00467dedA5e-9882.78% (209) hypothetical protein MLBr_00467
M. abscessus ATCC 19977MAB_4661-8e-1933.12% (160) hypothetical protein MAB_4661
M. marinum MMMAR_2063dedA1e-10483.49% (218) transmembrane protein DedA
M. avium 104MAV_3516-1e-9785.00% (200) integral membrane protein
M. smegmatis MC2 155MSMEG_0750-6e-1333.57% (140) membrane protein
M. thermoresistible (build 8)TH_1640-1e-1630.94% (181) POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_3280dedA1e-10483.03% (218) transmembrane protein DedA
M. vanbaalenii PYR-1Mvan_0668-1e-1131.03% (174) hypothetical protein Mvan_0668

CLUSTAL 2.0.9 multiple sequence alignment


Mb2670|M.bovis_AF2122/97            -------------------MDVEALLQSIPPLMVYLVVG--AVVGIES--
Rv2637|M.tuberculosis_H37Rv         -------------------MDVEALLQSIPPLMVYLVVG--AVVGIES--
MAV_3516|M.avium_104                ------------------------------------MVG--GVVGIES--
MMAR_2063|M.marinum_M               -------------------MDVEALLHTIPPLAVYILVG--AVVGVES--
MUL_3280|M.ulcerans_Agy99           -------------------MDVEALLHTIPPLAVYILVG--AVVGVES--
MLBr_00467|M.leprae_Br4923          -------------------MDVDALLQSIPPLAVYLLVS--GVVGVES--
Mflv_0237|M.gilvum_PYR-GCK          -------MVVDNLALMPDFLDPINLLS---YFGTWALIGLLVVVFVESGV
Mvan_0668|M.vanbaalenii_PYR-1       -------MVVDNLALMPDFLDPINLLS---YFGTWALIGLLVVVFVESGV
MSMEG_0750|M.smegmatis_MC2_155      MIDTALPEVTTNLALMPDFMDPLNLIG---YFGTWALVGILLVVFIESGV
MAB_4661|M.abscessus_ATCC_1997      ---------MDMGLAPADVMDPMYWLGEGGLFGGAVLAGVMVIVFIETGL
TH_1640|M.thermoresistible__bu      --------MSTTVMAMPGILDPMFWIGPDGLFAAAVLPAILIIVFIETGL
                                                                        : .   :* :*:  

Mb2670|M.bovis_AF2122/97            LGIPLPGEIVLVSAAVLSSHPELA----------VNPIGVGGAAVIGAVV
Rv2637|M.tuberculosis_H37Rv         LGIPLPGEIVLVSAAVLSSHPELA----------VNPIGVGGAAVIGAVV
MAV_3516|M.avium_104                LGIPLPGEIVLVTAALMSSHHDLA----------VNPLGVGVAAVIGAVI
MMAR_2063|M.marinum_M               LGIPLPGEIVLVSAALLSSHHELA----------VNPVGVGAAAVIGAVI
MUL_3280|M.ulcerans_Agy99           LGIPLPGEIVLVSAALLSSHHELA----------VNPVGVGAAAVIGAVI
MLBr_00467|M.leprae_Br4923          LGIPLPGEVVLVSAALLSSRHDLA----------VSSIGVGVVAVIGAAV
Mflv_0237|M.gilvum_PYR-GCK          LFPILPGDSLLFVAGMLAAGISAQSAEGNVAVVNFQLWQLLVFIPIAAVL
Mvan_0668|M.vanbaalenii_PYR-1       LFPVLPGDSLLFVAGMLAAGTAAASKEGNVANADFQLWQLLVFIPIAAVL
MSMEG_0750|M.smegmatis_MC2_155      LFPVLPGDSLLFVAGMLAAGTAAK---GTAVDANFQLWQLLVFIPIAAIL
MAB_4661|M.abscessus_ATCC_1997      LFPFLPGDTLLFSAGLIAAQPNSP----------VAIQVLAPCAALAALL
TH_1640|M.thermoresistible__bu      LFPLLPGDSLLFTGGLLAAG--GT----------MNIWLLCITVTIVAIL
                                    *   ***: :*. ..::::               .    :     : * :

Mb2670|M.bovis_AF2122/97            GDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFL
Rv2637|M.tuberculosis_H37Rv         GDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFL
MAV_3516|M.avium_104                GDSIGYAVGRRFGMPLFERLGRRFPKHFGPGHVALAEKLFNRWGARAVFL
MMAR_2063|M.marinum_M               GDSIGYTIGRRFGMPLFDRLGRRFPKHFGPGHVALAERLFSRWGSRAVFF
MUL_3280|M.ulcerans_Agy99           GDSIGYTIGRRFGMPLFDRLGRRFPKHFGPGHVALAERLFSRWGSQAVFF
MLBr_00467|M.leprae_Br4923          GDSIGYAIGRRFGMPLFDHLGRRFPKHFGPGHVALVERLFNRWGVRAVFF
Mflv_0237|M.gilvum_PYR-GCK          GAQVGYWIGRNVGTAMFTP-NARFLKQK---YLDEAHLFFEQRGPFAIVI
Mvan_0668|M.vanbaalenii_PYR-1       GAQVGYWIGRNVGTAMFKP-DARFLKQK---YLDEAHLFFEQRGPFAIVV
MSMEG_0750|M.smegmatis_MC2_155      GGQVGYIIGRTIGTSMFKP-EARILKQK---YLDEAHEFFEQRGPFAIVI
MAB_4661|M.abscessus_ATCC_1997      GSQCGYFIGRRLGPALFKKEDARFFKQR---YLTVSREFFDKHGPKTLLI
TH_1640|M.thermoresistible__bu      GDQCAYYIGRRIGPALFNKEDSRFFKKS---YVEQSHEFFEKYGPYTIIL
                                    * . .* :** .* .:*     *: *:    ::   . :*.: *  ::..

Mb2670|M.bovis_AF2122/97            GRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAG--
Rv2637|M.tuberculosis_H37Rv         GRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAG--
MAV_3516|M.avium_104                GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYFAG--
MMAR_2063|M.marinum_M               GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYYAG--
MUL_3280|M.ulcerans_Agy99           GRFIALLRILAGPLAGALKMHYPRFLTANVSGAICWAGGTTALVYYAG--
MLBr_00467|M.leprae_Br4923          GRFIALLRILAGPLAGALKMHYPRFLAANVSGAICWAGGTTALVYFAG--
Mflv_0237|M.gilvum_PYR-GCK          ARFVPIVRTLAPITAGAAKMNYAVFTLYNAVGAIVWGVGLTLLGFFLGRI
Mvan_0668|M.vanbaalenii_PYR-1       ARFVPIVRTLAPITAGAAKMNYAVFTVYNAVGAVVWGAGLTLLGYWLGRF
MSMEG_0750|M.smegmatis_MC2_155      ARFVPIVRTLAPITAGAAKMRYPVFTAFNVLGAIVWGVGLTLLGYWLGQF
MAB_4661|M.abscessus_ATCC_1997      AQFIGVVRTFTPVIAGMSGMRYPTFLLYNAIGSAAWGTGLTVVGYFLGNI
TH_1640|M.thermoresistible__bu      ARFVPIVRTYAPVLAGVSYMRYSVFLTFNAVGGIAWGTGVTLLGYFLGNI
                                    .:*: ::*  :   **   * *. *   *. *.  *. * * : :: *  

Mb2670|M.bovis_AF2122/97            MAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGT
Rv2637|M.tuberculosis_H37Rv         MAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGT
MAV_3516|M.avium_104                VAAERWLERFSWIGLVVAVVAGLTAAILLRERTSRAIAELEAEHYRKTGN
MMAR_2063|M.marinum_M               MAAEHWLQRFSWVGLVIAVVGGLIAAILLRERTARAIAELEEEHHRKAQT
MUL_3280|M.ulcerans_Agy99           MAAEHWLQRFSWVGLVIAVVGGLIAAILLRERTARAIAELEEEHHRKAQT
MLBr_00467|M.leprae_Br4923          MAAERWMERFSWIALIITVVVGIIAAILLRERTSRIIAELEMEYKNRRH-
Mflv_0237|M.gilvum_PYR-GCK          EIIQKLLEPIVIGIVILSVLPIAIEWYKRRKAAKQAGI--ATPPMEAGEQ
Mvan_0668|M.vanbaalenii_PYR-1       EVIQKLLEPIVIGIVLLSVLPMLIEWYRRRKAAKQAGG--ATEAEPTG--
MSMEG_0750|M.smegmatis_MC2_155      EIIQKLLEPIFILIVVASVAPMFIEWYKRRRAAKRASS--TDTATDAASP
MAB_4661|M.abscessus_ATCC_1997      AFVGEHLDIIILVIAILSTLPAAATAAKVYLEKRRAVT-----------E
TH_1640|M.thermoresistible__bu      TFVKENLEYMILLIVFLSVLPMIFSVTKGMLERRRARSGPALAAEPLPKQ
                                        . :: :     . :.               :               

Mb2670|M.bovis_AF2122/97            TAA---
Rv2637|M.tuberculosis_H37Rv         TAA---
MAV_3516|M.avium_104                TATDPV
MMAR_2063|M.marinum_M               AEA---
MUL_3280|M.ulcerans_Agy99           AEA---
MLBr_00467|M.leprae_Br4923          ------
Mflv_0237|M.gilvum_PYR-GCK          AG----
Mvan_0668|M.vanbaalenii_PYR-1       ------
MSMEG_0750|M.smegmatis_MC2_155      AS----
MAB_4661|M.abscessus_ATCC_1997      NG----
TH_1640|M.thermoresistible__bu      SG----