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RDAIPLGRIAGFVVNVHWSVLVILWLFTWSLATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHA VVARRAGVSVESVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAGVRTPAIVIS VAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSVRAGIGAARAGRVVALVLIALGLAEFVAGG LVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYP VADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTALLERMAPLGPRSRALVTEG SAVVGIVTPSDVARLIDVYRLAQPEPTFTTSPQDADRFSDAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2625c | - | - | 100% (393) | PROBABLE CONSERVED TRANSMEMBRANE ALANINE AND LEUCINE RICH PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2658c | - | 0.0 | 100.00% (393) | hypothetical protein Mb2658c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2075 | - | 1e-176 | 79.03% (391) | hypothetical protein MMAR_2075 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4327 | - | 2e-87 | 46.24% (372) | PUTATIVE putative peptidase M50 |
| M. ulcerans Agy99 | MUL_3269 | - | 1e-176 | 79.28% (391) | hypothetical protein MUL_3269 |
| M. vanbaalenii PYR-1 | Mvan_1412 | - | 1e-118 | 56.91% (369) | peptidase M50 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2625c|M.tuberculosis_H37Rv ------------------MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSL
Mb2658c|M.bovis_AF2122/97 ------------------MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSL
MMAR_2075|M.marinum_M MDRVGERCGAIRQVGGSAVSDEIPLGRIAGFAVKVHWSVLVILWLFTWSL
MUL_3269|M.ulcerans_Agy99 ------------------MSDEIPLGRIAGFAVKVHWSVLVILWLFTWSL
Mvan_1412|M.vanbaalenii_PYR-1 ------------------MEHGVALGRMRGLTVTVHWSVVVIVWLFAWSL
TH_4327|M.thermoresistible__bu -----------------VVKATVRLGRIAGIPVGVHWSVLGIVLLLVVGL
: : ***: *: * *****: *: *:. .*
Rv2625c|M.tuberculosis_H37Rv ATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVE
Mb2658c|M.bovis_AF2122/97 ATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVE
MMAR_2075|M.marinum_M ATTLPETAKGYGAVVYWIAGGCGALVLLASLLAHELAHAIAARRAGVPVG
MUL_3269|M.ulcerans_Agy99 ATTLPETAKGYGAVVYWIAGGCGALVLLASLLAHELAHAIAARRAGVPVG
Mvan_1412|M.vanbaalenii_PYR-1 ASTLPGSAPGYPDAVYWVAGFCGAALFAAGLLAHELAHAVVARRSGIPVP
TH_4327|M.thermoresistible__bu SVQLQSVVGGYPQAAYITAAFGTAALFVLSLLAHELAHAVVARRNGVEVD
: * . ** ..* . * :: .*********:.*** *: *
Rv2625c|M.tuberculosis_H37Rv SVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAG
Mb2658c|M.bovis_AF2122/97 SVTLWLFGGVTALGGEAKTPKAAFRIAFAGPATSLALSATFGALAITLAG
MMAR_2075|M.marinum_M NVTLWLFGGVTTLGGEAKTPKAAFRIAFAGPATSLALSAMFTAVAVALAM
MUL_3269|M.ulcerans_Agy99 NVTLWLFGGVTTLGGEAKTPKAAFRIAFAGPATSLALSAMFTAVAVALAM
Mvan_1412|M.vanbaalenii_PYR-1 EITLWLFGGVARLAGEAKTPRDEFRMAAAGPALSLALSAVFAAVAAGLAG
TH_4327|M.thermoresistible__bu GITLWLLGGVARLRGDALTPGAAFRIAVVGPLTSLLMAAIFGAATWLAEG
:****:***: * *:* ** **:* .** ** ::* * * :
Rv2625c|M.tuberculosis_H37Rv VRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSV
Mb2658c|M.bovis_AF2122/97 VRTPAIVISVAWWLATVNLLLGLFNLLPGAPLDGGRLVRAYLWRRHGDSV
MMAR_2075|M.marinum_M VRTPDLVVSVVWWLAAVNLMLGLFNLLPGAPLDGGRLVRAYLWRRHGDIV
MUL_3269|M.ulcerans_Agy99 VRTPDLVVSVVWWLAAVNLMLGLFNLLPGAPLDGGRLVRAYLWRRHGDIV
Mvan_1412|M.vanbaalenii_PYR-1 TGISPLATEVAAWLAAANAVLAVFNLLPGAPLDGGRILRAYLWHRHGDPV
TH_4327|M.thermoresistible__bu AGLGDLTHAVLLYLAIINVVLAVFNLIPAAPLDGGRILRAAIWAWRGDQY
. :. * :** * :*.:***:*.*******::** :* :**
Rv2625c|M.tuberculosis_H37Rv RAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREE
Mb2658c|M.bovis_AF2122/97 RAGIGAARAGRVVALVLIALGLAEFVAGGLVGGVWLAFIGWFIFAAAREE
MMAR_2075|M.marinum_M RAGIGAARAGRVVALILIILGLAEFVAGGLVGGVWLAFIGWFIFAAAREE
MUL_3269|M.ulcerans_Agy99 RAGIGAARAGRVVALVLIILGLAEFVAGGLVGGVWLVFIGWFIFAAAREE
Mvan_1412|M.vanbaalenii_PYR-1 RAAIGAARAGRVVAYLLIGLGLVEFLLGSLIGGAWLAFIGWFLLTAARDE
TH_4327|M.thermoresistible__bu VATVWAARAGRLFGFTLIALGLVQAMTG--LGGLWYILLGLFIVTMAGAE
* : ******:.. ** ***.: : * :** * ::* *:.: * *
Rv2625c|M.tuberculosis_H37Rv ETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPV
Mb2658c|M.bovis_AF2122/97 ETRISTQQLFAGVRVADAMTAQPHTAPGWINVEDFIQRYVLGERHSAYPV
MMAR_2075|M.marinum_M ETRISTQQLFTGLRVADAMTAHPHTAPGWIDVDEFIARYVLGDRHSAYPV
MUL_3269|M.ulcerans_Agy99 ETRISTQQLFTGLRVADAMTAHPHTAPGWIDVDEFIARYVLGDRHSAYPV
Mvan_1412|M.vanbaalenii_PYR-1 NAAVRARASLAGVRVAAVMTPNPRTVPESLSVQRFIDDHLLGDRHSAYPV
TH_4327|M.thermoresistible__bu EYQARTTAALAGVRVRDVMTPQPETVPGDLTVARFLHDVLLFRRHSAFPL
: : ::*:** .**.:*.*.* : * *: :* ****:*:
Rv2625c|M.tuberculosis_H37Rv ADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTA
Mb2658c|M.bovis_AF2122/97 ADRDGSITGLVALRQLRDVAPSRRSTTSVGDIALPLHSVPTARPQEPLTA
MMAR_2075|M.marinum_M TERDGSITGLVTLRQLRELAPERRGSTTVREIALPLHDVPTATPQEPLTT
MUL_3269|M.ulcerans_Agy99 TERDGSITGLVTLRQLRELAPERRGSTTVREIALPLHDVPTATPQEPLTT
Mvan_1412|M.vanbaalenii_PYR-1 THPDGTCTGLVTLAQVRVVPPVERDTTRLADIAIPRNRMATADPGEPLVE
TH_4327|M.thermoresistible__bu VDAFGRVEGLITLNRIRSLSPEERATALLRQVACPVNEVPTAAPDELLTD
.. * **::* ::* :.* .* :: : ::* * : :.** * * *.
Rv2625c|M.tuberculosis_H37Rv LLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTS
Mb2658c|M.bovis_AF2122/97 LLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTTS
MMAR_2075|M.marinum_M LLERMAPAGRGSRALVLDGGGVVGIVAASDIARLINVYRLAGPGATADSA
MUL_3269|M.ulcerans_Agy99 LLERMAPAGRGSRALVLDGGAVVGIVAASDIARLINVYRLAGPGATADSA
Mvan_1412|M.vanbaalenii_PYR-1 VVQRLDRS-TGNRIVVMAADRAIGVVTAADVARMIDVRNLAAVGQPAGPG
TH_4327|M.thermoresistible__bu LLPRLGGCADG-RALVFERGRLVGIVSPTDISRAAALHGLTAEIGSGGPD
:: *: * :* . :*:*:.:*::* : *: . .
Rv2625c|M.tuberculosis_H37Rv PQDADRFSDAG
Mb2658c|M.bovis_AF2122/97 PQDADRFSDAG
MMAR_2075|M.marinum_M DQ-HEKYSNAG
MUL_3269|M.ulcerans_Agy99 DQ-HEKYSNAG
Mvan_1412|M.vanbaalenii_PYR-1 NG---------
TH_4327|M.thermoresistible__bu ISPGHPWSR--