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VEHGVALGRMRGLTVTVHWSVVVIVWLFAWSLASTLPGSAPGYPDAVYWVAGFCGAALFAAGLLAHELAH AVVARRSGIPVPEITLWLFGGVARLAGEAKTPRDEFRMAAAGPALSLALSAVFAAVAAGLAGTGISPLAT EVAAWLAAANAVLAVFNLLPGAPLDGGRILRAYLWHRHGDPVRAAIGAARAGRVVAYLLIGLGLVEFLLG SLIGGAWLAFIGWFLLTAARDENAAVRARASLAGVRVAAVMTPNPRTVPESLSVQRFIDDHLLGDRHSAY PVTHPDGTCTGLVTLAQVRVVPPVERDTTRLADIAIPRNRMATADPGEPLVEVVQRLDRSTGNRIVVMAA DRAIGVVTAADVARMIDVRNLAAVGQPAGPGNG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1412 | - | - | 100% (383) | peptidase M50 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2658c | - | 1e-118 | 56.91% (369) | hypothetical protein Mb2658c |
| M. gilvum PYR-GCK | Mflv_3364 | - | 8e-06 | 36.08% (97) | hypothetical protein Mflv_3364 |
| M. tuberculosis H37Rv | Rv2625c | - | 1e-118 | 56.91% (369) | hypothetical protein Rv2625c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2075 | - | 1e-119 | 55.94% (379) | hypothetical protein MMAR_2075 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4327 | - | 3e-88 | 47.37% (380) | PUTATIVE putative peptidase M50 |
| M. ulcerans Agy99 | MUL_3269 | - | 1e-119 | 55.67% (379) | hypothetical protein MUL_3269 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2658c|M.bovis_AF2122/97 ------------------MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSL
Rv2625c|M.tuberculosis_H37Rv ------------------MRDAIPLGRIAGFVVNVHWSVLVILWLFTWSL
MMAR_2075|M.marinum_M MDRVGERCGAIRQVGGSAVSDEIPLGRIAGFAVKVHWSVLVILWLFTWSL
MUL_3269|M.ulcerans_Agy99 ------------------MSDEIPLGRIAGFAVKVHWSVLVILWLFTWSL
Mvan_1412|M.vanbaalenii_PYR-1 ------------------MEHGVALGRMRGLTVTVHWSVVVIVWLFAWSL
TH_4327|M.thermoresistible__bu -----------------VVKATVRLGRIAGIPVGVHWSVLGIVLLLVVGL
Mflv_3364|M.gilvum_PYR-GCK ------------------MNTAMSLLALLAFMLLTAGTAVFVAAEFSLTA
: : * : .: : . :.: : :
Mb2658c|M.bovis_AF2122/97 ATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVE
Rv2625c|M.tuberculosis_H37Rv ATMLPGTVGGYPAVVYWLLGAGGAVMLLASLLAHELAHAVVARRAGVSVE
MMAR_2075|M.marinum_M ATTLPETAKGYGAVVYWIAGGCGALVLLASLLAHELAHAIAARRAGVPVG
MUL_3269|M.ulcerans_Agy99 ATTLPETAKGYGAVVYWIAGGCGALVLLASLLAHELAHAIAARRAGVPVG
Mvan_1412|M.vanbaalenii_PYR-1 ASTLPGSAPGYPDAVYWVAGFCGAALFAAGLLAHELAHAVVARRSGIPVP
TH_4327|M.thermoresistible__bu SVQLQSVVGGYPQAAYITAAFGTAALFVLSLLAHELAHAVVARRNGVEVD
Mflv_3364|M.gilvum_PYR-GCK LERSTVEANVRSGDRRDAMVQRAHRSLSTQLSGAQVGISITTLATGFLAE
. : * . ::. ::.: *. .
Mb2658c|M.bovis_AF2122/97 SVTLWLFGG---VTALGGEAKTPKAAFRIAFAGPATSLALSATFG---AL
Rv2625c|M.tuberculosis_H37Rv SVTLWLFGG---VTALGGEAKTPKAAFRIAFAGPATSLALSATFG---AL
MMAR_2075|M.marinum_M NVTLWLFGG---VTTLGGEAKTPKAAFRIAFAGPATSLALSAMFT---AV
MUL_3269|M.ulcerans_Agy99 NVTLWLFGG---VTTLGGEAKTPKAAFRIAFAGPATSLALSAMFT---AV
Mvan_1412|M.vanbaalenii_PYR-1 EITLWLFGG---VARLAGEAKTPRDEFRMAAAGPALSLALSAVFA---AV
TH_4327|M.thermoresistible__bu GITLWLLGG---VARLRGDALTPGAAFRIAVVGPLTSLLMAAIFG---AA
Mflv_3364|M.gilvum_PYR-GCK PVVARLIHPGLTALNVPGQFVSGLSLFLAILIATSISMIFGELVPKNLAV
:. *: . : *: : * .. *: :. . *
Mb2658c|M.bovis_AF2122/97 AITLAGVRTPAIVISVAWWLAT---------VNLLLGLFNLLPGAPLDGG
Rv2625c|M.tuberculosis_H37Rv AITLAGVRTPAIVISVAWWLAT---------VNLLLGLFNLLPGAPLDGG
MMAR_2075|M.marinum_M AVALAMVRTPDLVVSVVWWLAA---------VNLMLGLFNLLPGAPLDGG
MUL_3269|M.ulcerans_Agy99 AVALAMVRTPDLVVSVVWWLAA---------VNLMLGLFNLLPGAPLDGG
Mvan_1412|M.vanbaalenii_PYR-1 AAGLAGTGISPLATEVAAWLAA---------ANAVLAVFNLLPGAPLDGG
TH_4327|M.thermoresistible__bu TWLAEGAGLGDLTHAVLLYLAI---------INVVLAVFNLIPAAPLDGG
Mflv_3364|M.gilvum_PYR-GCK AKPVPTARWSAPLQLMFSFLALPLIRLTNGTANWILRRLGIEPAEELRSA
: . : :** * :* :.: *. * ..
Mb2658c|M.bovis_AF2122/97 RLVRAYLWRRHGDSVRAGIGAARAGRVVALVLI----------------A
Rv2625c|M.tuberculosis_H37Rv RLVRAYLWRRHGDSVRAGIGAARAGRVVALVLI----------------A
MMAR_2075|M.marinum_M RLVRAYLWRRHGDIVRAGIGAARAGRVVALILI----------------I
MUL_3269|M.ulcerans_Agy99 RLVRAYLWRRHGDIVRAGIGAARAGRVVALVLI----------------I
Mvan_1412|M.vanbaalenii_PYR-1 RILRAYLWHRHGDPVRAAIGAARAGRVVAYLLI----------------G
TH_4327|M.thermoresistible__bu RILRAAIWAWRGDQYVATVWAARAGRLFGFTLI----------------A
Mflv_3364|M.gilvum_PYR-GCK RSPQELVSLVRSSAERGSLDPVTAQLVDRSLQFGDRTAEELMTPRSKIDT
* : : :.. . : .. * : :
Mb2658c|M.bovis_AF2122/97 LGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAM
Rv2625c|M.tuberculosis_H37Rv LGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFAGVRVADAM
MMAR_2075|M.marinum_M LGLAEFVAGGLVGGVWLAFIGWFIFAAAREEETRISTQQLFTGLRVADAM
MUL_3269|M.ulcerans_Agy99 LGLAEFVAGGLVGGVWLVFIGWFIFAAAREEETRISTQQLFTGLRVADAM
Mvan_1412|M.vanbaalenii_PYR-1 LGLVEFLLGSLIGGAWLAFIGWFLLTAARDENAAVRARASLAGVRVAAVM
TH_4327|M.thermoresistible__bu LGLVQAMTG--LGGLWYILLGLFIVTMAGAEEYQARTTAALAGVRVRDVM
Mflv_3364|M.gilvum_PYR-GCK LDADDTVLDLSEAAVSTGHSRFPVIHGDLDETIGMVHVKQVFEVPAVSRS
*. : : . .. :. * . : .
Mb2658c|M.bovis_AF2122/97 TA-------QPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVA
Rv2625c|M.tuberculosis_H37Rv TA-------QPHTAPGWINVEDFIQRYVLGERHSAYPVADRDGSITGLVA
MMAR_2075|M.marinum_M TA-------HPHTAPGWIDVDEFIARYVLGDRHSAYPVTERDGSITGLVT
MUL_3269|M.ulcerans_Agy99 TA-------HPHTAPGWIDVDEFIARYVLGDRHSAYPVTERDGSITGLVT
Mvan_1412|M.vanbaalenii_PYR-1 TP-------NPRTVPESLSVQRFIDDHLLGDRHSAYPVTHPDGTCTGLVT
TH_4327|M.thermoresistible__bu TP-------QPETVPGDLTVARFLHDVLLFRRHSAFPLVDAFGRVEGLIT
Mflv_3364|M.gilvum_PYR-GCK TTRLADLVQPLTKVPSTLDGDAVMAEVRANGLQTALVVDEYGGTAGMVTV
*. ..* : .: ::* : . * : .
Mb2658c|M.bovis_AF2122/97 LRQLRDVAPSRRSTTSVG--DIALP-----------LHSVPTARPQEPLT
Rv2625c|M.tuberculosis_H37Rv LRQLRDVAPSRRSTTSVG--DIALP-----------LHSVPTARPQEPLT
MMAR_2075|M.marinum_M LRQLRELAPERRGSTTVR--EIALP-----------LHDVPTATPQEPLT
MUL_3269|M.ulcerans_Agy99 LRQLRELAPERRGSTTVR--EIALP-----------LHDVPTATPQEPLT
Mvan_1412|M.vanbaalenii_PYR-1 LAQVRVVPPVERDTTRLA--DIAIP-----------RNRMATADPGEPLV
TH_4327|M.thermoresistible__bu LNRIRSLSPEERATALLR--QVACP-----------VNEVPTAAPDELLT
Mflv_3364|M.gilvum_PYR-GCK EDLIEEIVGDVRDEHDDEPPDVVAAGQGWQVSGLLRIDEVAEGTAFRAPE
:. : * ::. . . :. . . .
Mb2658c|M.bovis_AF2122/97 ALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTT
Rv2625c|M.tuberculosis_H37Rv ALLERMAPLGPRSRALVTEGSAVVGIVTPSDVARLIDVYRLAQPEPTFTT
MMAR_2075|M.marinum_M TLLERMAPAGRGSRALVLDGGGVVGIVAASDIARLINVYRLAGPGATADS
MUL_3269|M.ulcerans_Agy99 TLLERMAPAGRGSRALVLDGGAVVGIVAASDIARLINVYRLAGPGATADS
Mvan_1412|M.vanbaalenii_PYR-1 EVVQRLDRS-TGNRIVVMAADRAIGVVTAADVARMIDVRNLAAVGQPAGP
TH_4327|M.thermoresistible__bu DLLPRLGGCADG-RALVFERGRLVGIVSPTDISRAAALHGLTAEIGSGGP
Mflv_3364|M.gilvum_PYR-GCK GDYETIGGLILEKLGHIPDEGETVELTAFDPDGAIEDPVRWLATVIKMDG
: : . : :.: .
Mb2658c|M.bovis_AF2122/97 SPQDADRFSDAG-------------
Rv2625c|M.tuberculosis_H37Rv SPQDADRFSDAG-------------
MMAR_2075|M.marinum_M ADQ-HEKYSNAG-------------
MUL_3269|M.ulcerans_Agy99 ADQ-HEKYSNAG-------------
Mvan_1412|M.vanbaalenii_PYR-1 GNG----------------------
TH_4327|M.thermoresistible__bu DISPGHPWSR---------------
Mflv_3364|M.gilvum_PYR-GCK RRIDQLRLTRLGRLSDAPEGEDHRG