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M. tuberculosis H37Rv Rv2594c (ruvC)

annotation: Holliday junction resolvase
coordinates: 2924817 - 2925383
length: 188

RVMGVDPGLTRCGLSLIESGRGRQLTALDVDVVRTPSDAALAQRLLAISDAVEHWLDTHHPEVVAIERVF
SQLNVTTVMGTAQAGGVIALAAAKRGVDVHFHTPSEVKAAVTGNGSADKAQVTAMVTKILALQAKPTPAD
AADALALAICHCWRAPTIARMAEATSRAEARAAQQRHAYLAKLKAAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2594cruvC-100% (188)Holliday junction resolvase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2625cruvC1e-102100.00% (188) Holliday junction resolvase
M. gilvum PYR-GCKMflv_3826ruvC5e-8080.11% (186) Holliday junction resolvase
M. leprae Br4923MLBr_00481ruvC7e-8380.98% (184) Holliday junction resolvase
M. abscessus ATCC 19977MAB_2884c-1e-6671.93% (171) crossover junction endodeoxyribonuclease RuvC
M. marinum MMMAR_2109ruvC1e-8584.57% (188) crossover junction endodeoxyribonuclease RuvC
M. avium 104MAV_3475ruvC4e-8483.87% (186) Holliday junction resolvase
M. smegmatis MC2 155MSMEG_2943ruvC3e-7977.13% (188) Holliday junction resolvase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1714ruvC7e-8684.57% (188) Holliday junction resolvase
M. vanbaalenii PYR-1Mvan_2573ruvC2e-7878.49% (186) Holliday junction resolvase

CLUSTAL 2.0.9 multiple sequence alignment


Rv2594c|M.tuberculosis_H37Rv        ----------------------------MRVMGVDPGLTRCGLSLIESGR
Mb2625c|M.bovis_AF2122/97           ----------------------------MRVMGVDPGLTRCGLSLIESGR
MMAR_2109|M.marinum_M               ----------------------------MRVMGVDPGLTRCGLSLIESGQ
MUL_1714|M.ulcerans_Agy99           ----------------------------MRVMGVDPGLTRCGLSLIESGQ
MLBr_00481|M.leprae_Br4923          ----------------------------MRVMGVDPGLTRCGLSVVENGR
MAV_3475|M.avium_104                ----------------------------MRVMGVDPGLTRCGLSVVESGR
Mflv_3826|M.gilvum_PYR-GCK          MRGARVPARSRRSQKLSSRTNVHRKGAGVRVMGVDPGLTRCGLSVIESGR
Mvan_2573|M.vanbaalenii_PYR-1       ----------------------------MRVMGVDPGLTRCGLSVIESGK
MSMEG_2943|M.smegmatis_MC2_155      ----------------------------MRVMGVDPGLTRCGLSMIESGK
MAB_2884c|M.abscessus_ATCC_199      --------------------------------------------MVEASS
                                                                                ::* . 

Rv2594c|M.tuberculosis_H37Rv        GRQLTALDVDVVRTPSDAALAQRLLAISDAVEHWLDTHHPEVVAIERVFS
Mb2625c|M.bovis_AF2122/97           GRQLTALDVDVVRTPSDAALAQRLLAISDAVEHWLDTHHPEVVAIERVFS
MMAR_2109|M.marinum_M               GRQLTALDVDVVRTPSDAPLSSRLLAINEAVEHWLETHRPDVVAIERVFS
MUL_1714|M.ulcerans_Agy99           GRQLTALDVDVVRTPSDAPLSSRLLAINEAVEHWLETHRPDVVAIERVFS
MLBr_00481|M.leprae_Br4923          GSQVVALDVDVVRTPSDAPVSKRLLAVSDVVEHWLDAHHPDVMAIERVFS
MAV_3475|M.avium_104                GRTVVALDVDVVRTPSDAPLAERLLSISDAVEHWLATHQPDVVAIERVFS
Mflv_3826|M.gilvum_PYR-GCK          GRQVIALDVDVVRTPSDHPLAHRLLAISNAVEHWLDTHRPDVIAIERVFS
Mvan_2573|M.vanbaalenii_PYR-1       GRQVIALDVDVVRTPAGHPLAHRLLAISDAVDHWLDTHRPDVIAIERVFS
MSMEG_2943|M.smegmatis_MC2_155      GRQVIALDVDVVRTPADTPLQKRLLTISDAAEHWMDTHRPDVIAIERVFA
MAB_2884c|M.abscessus_ATCC_199      GRKVVALDVDVVRTPANQPLPQRLLVISEVVEHWMETHRPDVVAIERVFA
                                    *  : **********:. .:  *** :.:..:**: :*:*:*:******:

Rv2594c|M.tuberculosis_H37Rv        QLNVTTVMGTAQAGGVIALAAAKRGVDVHFHTPSEVKAAVTGNGSADKAQ
Mb2625c|M.bovis_AF2122/97           QLNVTTVMGTAQAGGVIALAAAKRGVDVHFHTPSEVKAAVTGNGSADKAQ
MMAR_2109|M.marinum_M               QQNVKTVMGTAQAGGVVALAAAKRGVEVHFHTPSEVKAAVTGNGTADKAQ
MUL_1714|M.ulcerans_Agy99           QQNVKTVMGTAQAGGVVALAAAKRGVEVHFHTPSEVKAAVTGNGTADKAQ
MLBr_00481|M.leprae_Br4923          QQNVSTVMGTAQAGGVIALAAARRGIDVHFHTPSEVKAAVTGNGAANKAQ
MAV_3475|M.avium_104                QLNVTTVMGTAQAGGVVALAAAKRGIGVHFHTPSEVKAAVTGNGAANKAQ
Mflv_3826|M.gilvum_PYR-GCK          NQNANTAMGTAQAGGVVALAAARRDIDVHFHTPSEVKAAVTGNGRADKAQ
Mvan_2573|M.vanbaalenii_PYR-1       NQNANTAMGTAQAGGVIALAAARRDIDVHFHTPSEVKAAVTGNGRADKAQ
MSMEG_2943|M.smegmatis_MC2_155      NQNANTAMGTAQAGGVIALAAAKRDIEVHFHTPSEVKAAVTGSGRADKSQ
MAB_2884c|M.abscessus_ATCC_199      QQNVSTVMGTAQAGGVIALCAAKRGIEVYFHTPSEVKAAVTGNGRADKSQ
                                    : *..*.*********:**.**:*.: *:*************.* *:*:*

Rv2594c|M.tuberculosis_H37Rv        VTAMVTKILALQAKPTPADAADALALAICHCWRAPTIARMAEATSRAEAR
Mb2625c|M.bovis_AF2122/97           VTAMVTKILALQAKPTPADAADALALAICHCWRAPTIARMAEATSRAEAR
MMAR_2109|M.marinum_M               VTAMVTRILALQTKPTPADAADALALAICHCWRAPMIAQMAKAHALAE--
MUL_1714|M.ulcerans_Agy99           VTAMVTRILALQTKPTPADAADALALAICHCWRAPMIAQMAKAHALAE--
MLBr_00481|M.leprae_Br4923          VTAMVTRILALQAKPTPADAADALALAICHCWRAPMIARMAEAEALGARH
MAV_3475|M.avium_104                VTAMVTRILALQAKPTPADAADALALAICHCWRAPMIARMARAEALAAQQ
Mflv_3826|M.gilvum_PYR-GCK          VTEMVTRILALQQKPTPADAADALALAICHCWRAPMISRMAAAEEMAA--
Mvan_2573|M.vanbaalenii_PYR-1       VTEMVTRILALQQKPTPADAADALALAICHCWRAPMLGRMAAAEEMAA--
MSMEG_2943|M.smegmatis_MC2_155      VTEMVTRILALQAKPTPADAADALALAICHCWRAPMIARMAAAEAMAE--
MAB_2884c|M.abscessus_ATCC_199      VTAMVTRILNLQAAPKPADAADALALAICHCWRAPMLARMAKAEAVAE--
                                    ** ***:** **  *.******************* :.:** *   .   

Rv2594c|M.tuberculosis_H37Rv        AAQQRHAYLAKLKAAR----------
Mb2625c|M.bovis_AF2122/97           AAQQRHAYLAKLKAAR----------
MMAR_2109|M.marinum_M               --QQRRSYTAKLKAAR----------
MUL_1714|M.ulcerans_Agy99           --QQRRSYTAKLKAAR----------
MLBr_00481|M.leprae_Br4923          RQAYRAKVAGEVKATR----------
MAV_3475|M.avium_104                RQKYKDKVDATLRAAR----------
Mflv_3826|M.gilvum_PYR-GCK          --EQRRKYQATLKAKTR--QVSRSAR
Mvan_2573|M.vanbaalenii_PYR-1       --EQRRKYQATLKAKAKAAQMSRSTR
MSMEG_2943|M.smegmatis_MC2_155      --EQRRKFQAKIKAARG---------
MAB_2884c|M.abscessus_ATCC_199      --EQRKAFAARMKAAAR---------
                                        :    . ::*